The network for 'regulation of response to biotic stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to biotic stimulus

Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.

NameDescriptionProbabilityFunc Analog Organism
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.995
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.934
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.904
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.891
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.840
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.821
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.754
IFIT3interferon-induced protein with tetratricopeptide repeats 30.695
MAP3K8mitogen-activated protein kinase kinase kinase 80.621
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.614
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.609
IFIT5interferon-induced protein with tetratricopeptide repeats 50.570
IFIT1interferon-induced protein with tetratricopeptide repeats 10.495
STAT1signal transducer and activator of transcription 1, 91kDa0.488
TLR4toll-like receptor 40.482
IFI44interferon-induced protein 440.464
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.444
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.412
IFIT2interferon-induced protein with tetratricopeptide repeats 20.377
TNIP2TNFAIP3 interacting protein 20.374
SMAD4SMAD family member 40.363
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.351
DICER1dicer 1, ribonuclease type III0.350
RNF11ring finger protein 110.348
IFIH1interferon induced with helicase C domain 10.321
IL4Rinterleukin 4 receptor0.317
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.299
RXRAretinoid X receptor, alpha0.288
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.287
SMURF2SMAD specific E3 ubiquitin protein ligase 20.286
PLSCR1phospholipid scramblase 10.274
NCF1neutrophil cytosolic factor 10.270
MYD88myeloid differentiation primary response gene (88)0.257
JUNjun proto-oncogene0.255
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.247
IRAK1interleukin-1 receptor-associated kinase 10.229
IL8interleukin 80.215
TNFAIP3tumor necrosis factor, alpha-induced protein 30.214
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.203
NLRC4NLR family, CARD domain containing 40.192
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.189
PAX3paired box 30.175
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.174
MED15mediator complex subunit 150.173
SP110SP110 nuclear body protein0.172
SP100SP100 nuclear antigen0.170
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.167
SAMD9sterile alpha motif domain containing 90.161
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.159
CYLDcylindromatosis (turban tumor syndrome)0.155
NMIN-myc (and STAT) interactor0.148
HERC5hect domain and RLD 50.142
DAXXdeath-domain associated protein0.134
IL23Ainterleukin 23, alpha subunit p190.133
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.117
PCBP1poly(rC) binding protein 10.117
TRIM22tripartite motif containing 220.112
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.112
PMLpromyelocytic leukemia0.110
ATF3activating transcription factor 30.108
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.105
JUNBjun B proto-oncogene0.103
LY96lymphocyte antigen 960.095
MAP3K14mitogen-activated protein kinase kinase kinase 140.094
COPS6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.093
ATG3ATG3 autophagy related 3 homolog (S. cerevisiae)0.093
HDAC6histone deacetylase 60.092
TLR2toll-like receptor 20.092
FOSFBJ murine osteosarcoma viral oncogene homolog0.090
TRIM21tripartite motif containing 210.090
TMEM173transmembrane protein 1730.086
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.084
ISG15ISG15 ubiquitin-like modifier0.081
CXCL2chemokine (C-X-C motif) ligand 20.080
TRIM39tripartite motif containing 390.080
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.079
STAP2signal transducing adaptor family member 20.074
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.073
IFI16interferon, gamma-inducible protein 160.073
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.071
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.070
BIRC3baculoviral IAP repeat containing 30.070
NEDD4neural precursor cell expressed, developmentally down-regulated 40.069
GBP1guanylate binding protein 1, interferon-inducible0.068
PRKCAprotein kinase C, alpha0.068
NLRP3NLR family, pyrin domain containing 30.066
PVRL4poliovirus receptor-related 40.066
TLR1toll-like receptor 10.061
IRF2interferon regulatory factor 20.061
CXCL3chemokine (C-X-C motif) ligand 30.060
PARP9poly (ADP-ribose) polymerase family, member 90.059
NOD2nucleotide-binding oligomerization domain containing 20.057
TRAF6TNF receptor-associated factor 60.057
MOV10Mov10, Moloney leukemia virus 10, homolog (mouse)0.056
INSRinsulin receptor0.054
APOL6apolipoprotein L, 60.054
TDRD7tudor domain containing 70.053
IL15interleukin 150.053
CHUKconserved helix-loop-helix ubiquitous kinase0.052
MEFVMediterranean fever0.052
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nod1nucleotide-binding oligomerization domain containing 10.178
ripk2receptor-interacting serine-threonine kinase 20.171
socs3asuppressor of cytokine signaling 3a0.129
caspacaspase a0.090
gata5GATA-binding protein 50.086
gata6GATA-binding protein 60.082
LOC557072caspase recruitment domain-containing protein 11-like0.081
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.077
st3gal5lST3 beta-galactoside alpha-2,3-sialyltransferase 5, like0.070
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.068
ahcyS-adenosylhomocysteine hydrolase0.066
smyhc1slow myosin heavy chain 10.066
dhfrdihydrofolate reductase0.065
znf148zinc finger protein 1480.065
aldh1a2aldehyde dehydrogenase 1 family, member A20.061
tsen54tRNA splicing endonuclease 54 homolog (S. cerevisiae)0.053
LOC100004946transient receptor potential cation channel subfamily M member 4-like0.051
myod1myogenic differentiation 10.051
relv-rel reticuloendotheliosis viral oncogene homolog0.051
impdh2IMP (inosine monophosphate) dehydrogenase 20.051
pycardPYD and CARD domain containing0.050
tp53tumor protein p530.048
pdlim7PDZ and LIM domain 70.046
irak4interleukin-1 receptor-associated kinase 40.045
si:ch211-195h23.3si:ch211-195h23.30.043
zgc:92851zgc:928510.043
eng2aengrailed 2a0.042
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.042
LOC566708FL cytokine receptor-like0.042
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.042
il6stinterleukin 6 signal transducer0.040
si:dkey-236e20.2si:dkey-236e20.20.040
btg2B-cell translocation gene 20.039
hspa5heat shock protein 50.039
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.038
eporerythropoietin receptor0.038
aplnrbapelin receptor b0.037
unc5dbunc-5 homolog Db (C. elegans)0.037
pdcd2programmed cell death 20.036
nkx2.2aNK2 transcription factor related 2a0.036
spawsouthpaw0.035
fosv-fos FBJ murine osteosarcoma viral oncogene homolog0.035
klf2bKruppel-like factor 2b0.035
ppargperoxisome proliferator activated receptor gamma0.035
ef1aelongation factor 1-alpha0.034
unc5cunc-5 homolog C (C. elegans)0.034
card14caspase recruitment domain family, member 140.034
hmbsbhydroxymethylbilane synthase, b0.034
phlda2pleckstrin homology-like domain, family A, member 20.033
LOC100151531zinc finger protein Gfi-1b-like0.033
cdkrap3CDK5 regulatory subunit associated protein 30.033
si:dkeyp-7c9.1si:dkeyp-7c9.10.032
ip6k2inositol hexaphosphate kinase 20.032
slc4a4bsolute carrier family 4, sodium bicarbonate cotransporter, member 4b0.032
rhagRhesus blood group-associated glycoprotein0.032
sec24cSEC24 family, member C (S. cerevisiae)0.031
nfycnuclear transcription factor Y, gamma0.031
sp2sp2 transcription factor0.030
tax1bp1bTax1 (human T-cell leukemia virus type I) binding protein 1b0.030
ca2carbonic anhydrase II0.030
polr2apolymerase (RNA) II (DNA directed) polypeptide A0.030
LOC559454glypican-5-like0.030
zgc:110340zgc:1103400.030
otpborthopedia homolog b0.029
zgc:66286zgc:662860.029
smyd3SET and MYND domain containing 30.029
arl6ip1ADP-ribosylation factor-like 6 interacting protein 10.028
cyp2k16cytochrome P450, family 2, subfamily K, polypeptide160.028
fabp2fatty acid binding protein 2, intestinal0.028
mcl1amyeloid cell leukemia sequence 1a0.028
rorcaRAR-related orphan receptor C a0.028
stc1lstanniocalcin 1, like0.028
zgc:64141zgc:641410.028
trpv6transient receptor potential cation channel, subfamily V, member 60.028
zgc:66317zgc:663170.027
smoc2secreted modular calcium binding protein 20.027
smarcal1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 10.027
stat1bsignal transducer and activator of transcription 1b0.027
setd5SET domain containing 50.027
ogg18-oxoguanine DNA glycosylase0.027
ndr2nodal-related 20.026
trim55btripartite motif-containing 55b0.026
zgc:56518zgc:565180.026
plekha1pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 10.026
ptges3aprostaglandin E synthase 3a (cytosolic)0.026
zgc:56376zgc:563760.025
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.025
pdia4protein disulfide isomerase associated 40.025
lndc1ly6/neurotoxin domain containing 10.025
crip2cysteine-rich protein 20.025
ptpn9aprotein tyrosine phosphatase, non-receptor type 9, a0.025
gabarapaGABA(A) receptor-associated protein a0.025
etnk1ethanolamine kinase 10.025
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.025
metap2methionyl aminopeptidase 20.025
ptk6aPTK6 protein tyrosine kinase 6a0.024
npy8brneuropeptide Y receptor Y8b0.024
itih2inter-alpha (globulin) inhibitor H20.024
rab22aRAB22A, member RAS oncogene family0.024
zeb2bzinc finger E-box binding homeobox 2b0.024
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
RelRelish0.998
Mpk2CG5475 gene product from transcript CG5475-RB0.885
keykenny0.809
Spn27ASerpin 27A0.806
TlToll0.790
PGRP-LCPeptidoglycan recognition protein LC0.784
Spn1Serine protease inhibitor 10.741
ird5immune response deficient 50.738
DreddDeath related ced-3/Nedd2-like protein0.711
imdimmune deficiency0.670
p38bCG7393 gene product from transcript CG7393-RA0.662
PGRP-SAPeptidoglycan recognition protein SA0.614
SPESpatzle-Processing Enzyme0.595
spzspatzle0.554
Atg18Autophagy-specific gene 180.552
fonfondue0.529
Galpha49BG protein alpha49B0.517
Spn28DSerpin 28D0.498
grassGram-positive Specific Serine protease0.467
Toll-7CG8595 gene product from transcript CG8595-RA0.447
PGRP-SDCG7496 gene product from transcript CG7496-RA0.436
ird1immune response deficient 10.433
Mekk1CG7717 gene product from transcript CG7717-RB0.427
PGRP-LBPeptidoglycan recognition protein LB0.403
cactcactus0.379
DptBDiptericin B0.362
psqpipsqueak0.348
necnecrotic0.340
Ndae1Na[+]-driven anion exchanger 10.334
rprreaper0.323
BG4CG12297 gene product from transcript CG12297-RA0.319
Lis-1Lissencephaly-10.311
nubnubbin0.305
Myd88CG2078 gene product from transcript CG2078-RA0.254
MtkMetchnikowin0.249
pirkpoor Imd response upon knock-in0.232
AGO2Argonaute 20.224
LmptLimpet0.219
CG6664CG6664 gene product from transcript CG6664-RC0.218
tamoCG4057 gene product from transcript CG4057-RA0.208
egreiger0.200
Atg13Autophagy-specific gene 130.178
CG12766CG12766 gene product from transcript CG12766-RA0.173
18w18 wheeler0.163
Tak1TGF-beta activated kinase 10.161
rlrolled0.160
CG18594CG18594 gene product from transcript CG18594-RA0.156
whdwithered0.148
amosabsent MD neurons and olfactory sensilla0.137
mib1mind bomb 10.136
PGRP-LFPeptidoglycan recognition protein LF0.133
Adf1Adh transcription factor 10.132
CG9184CG9184 gene product from transcript CG9184-RB0.130
lolallola like0.130
ChcClathrin heavy chain0.128
krzkurtz0.128
AttCAttacin-C0.127
Sp7Serine protease 70.123
Trx-2thioredoxin-20.122
ScmSex comb on midleg0.121
upd2unpaired 20.120
Tab2TAK1-associated binding protein 20.120
nmonemo0.114
eaterCG6124 gene product from transcript CG6124-RB0.113
oddodd skipped0.112
Toll-6CG7250 gene product from transcript CG7250-RA0.108
CG15917CG15917 gene product from transcript CG15917-RA0.106
ushu-shaped0.101
pxplexus0.100
CG11286CG11286 gene product from transcript CG11286-RA0.098
CG7910CG7910 gene product from transcript CG7910-RA0.097
AttAAttacin-A0.095
DuoxDual oxidase0.095
PliPellino0.092
CG16718CG16718 gene product from transcript CG16718-RA0.090
StamSignal transducing adaptor molecule0.090
upd3unpaired 30.088
plepale0.087
subsubito0.084
Taf4TBP-associated factor 40.077
TolloCG6890 gene product from transcript CG6890-RA0.076
ArkApaf-1-related-killer0.076
pshpersephone0.076
p53CG33336 gene product from transcript CG33336-RB0.071
bskbasket0.070
CG10650CG10650 gene product from transcript CG10650-RA0.068
Wnt2Wnt oncogene analog 20.068
Pi3K59FPhosphotidylinositol 3 kinase 59F0.068
MadMothers against dpp0.067
Sema-1bCG6446 gene product from transcript CG6446-RA0.065
Uba1Ubiquitin activating enzyme 10.064
l(3)05822lethal (3) 058220.062
kaykayak0.061
Atg2Autophagy-specific gene 20.061
CG13641CG13641 gene product from transcript CG13641-RA0.061
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.060
Rbp6RNA-binding protein 60.060
hydhyperplastic discs0.060
lwrlesswright0.059
GNBP3Gram-negative bacteria binding protein 30.059
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Casp4caspase 4, apoptosis-related cysteine peptidase0.997
Casp1caspase 10.978
Trim30atripartite motif-containing 30A0.918
Gbp7guanylate binding protein 70.859
Gbp2guanylate binding protein 20.834
Gbp3guanylate binding protein 30.820
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.811
Ighimmunoglobulin heavy chain complex0.800
Iigp1interferon inducible GTPase 10.798
PycardPYD and CARD domain containing0.724
Irgm1immunity-related GTPase family M member 10.723
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.714
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.710
Trp53transformation related protein 530.683
Cyldcylindromatosis (turban tumor syndrome)0.654
Birc3baculoviral IAP repeat-containing 30.635
Lyz2lysozyme 20.604
Tnftumor necrosis factor0.594
Ikbkginhibitor of kappaB kinase gamma0.572
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.544
Trim21tripartite motif-containing 210.537
Cd40CD40 antigen0.532
Stat3signal transducer and activator of transcription 30.531
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.517
Ifi44interferon-induced protein 440.486
Sfpi1SFFV proviral integration 10.485
Isg15ISG15 ubiquitin-like modifier0.477
Stat1signal transducer and activator of transcription 10.448
Irgm2immunity-related GTPase family M member 20.399
Uba7ubiquitin-like modifier activating enzyme 70.399
Ifih1interferon induced with helicase C domain 10.393
Igtpinterferon gamma induced GTPase0.384
Unc93b1unc-93 homolog B1 (C. elegans)0.384
Ccl4chemokine (C-C motif) ligand 40.383
Ifi203interferon activated gene 2030.377
Ifi47interferon gamma inducible protein 470.374
SkilSKI-like0.357
Parp14poly (ADP-ribose) polymerase family, member 140.313
Rxraretinoid X receptor alpha0.306
Irf1interferon regulatory factor 10.277
Traf2TNF receptor-associated factor 20.273
Ticam1toll-like receptor adaptor molecule 10.270
Tgtp2T-cell specific GTPase 20.262
Nfkbienuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.262
Cxcl2chemokine (C-X-C motif) ligand 20.259
Traf6TNF receptor-associated factor 60.248
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.238
Tnfaip3tumor necrosis factor, alpha-induced protein 30.234
FosFBJ osteosarcoma oncogene0.228
Rtp4receptor transporter protein 40.221
Parp9poly (ADP-ribose) polymerase family, member 90.217
Mavsmitochondrial antiviral signaling protein0.216
Gbp6guanylate binding protein 60.200
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.198
Irf9interferon regulatory factor 90.192
Ifit1interferon-induced protein with tetratricopeptide repeats 10.188
Myd88myeloid differentiation primary response gene 880.183
Cxcl10chemokine (C-X-C motif) ligand 100.181
Socs1suppressor of cytokine signaling 10.177
Mndalmyeloid nuclear differentiation antigen like0.173
Irf8interferon regulatory factor 80.152
Erap1endoplasmic reticulum aminopeptidase 10.152
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.150
Mndamyeloid cell nuclear differentiation antigen0.149
Gbp5guanylate binding protein 50.147
Aim2absent in melanoma 20.144
Map3k8mitogen-activated protein kinase kinase kinase 80.141
Ikbkbinhibitor of kappaB kinase beta0.139
Atf3activating transcription factor 30.138
Hspa9heat shock protein 90.136
Serpinb9serine (or cysteine) peptidase inhibitor, clade B, member 90.131
BC006779cDNA sequence BC0067790.130
D14Ertd668eDNA segment, Chr 14, ERATO Doi 668, expressed0.129
Samd9lsterile alpha motif domain containing 9-like0.128
Nlrp3NLR family, pyrin domain containing 30.120
Gbp10guanylate-binding protein 100.117
2010106G01RikRIKEN cDNA 2010106G01 gene0.117
Ifit3interferon-induced protein with tetratricopeptide repeats 30.115
Irf7interferon regulatory factor 70.115
Socs3suppressor of cytokine signaling 30.114
Mknk2MAP kinase-interacting serine/threonine kinase 20.113
Rsad2radical S-adenosyl methionine domain containing 20.112
Oasl22'-5' oligoadenylate synthetase-like 20.111
Mapk14mitogen-activated protein kinase 140.108
Nfkbiznuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.107
Cd14CD14 antigen0.104
Gata4GATA binding protein 40.099
JunbJun-B oncogene0.099
Ccr2chemokine (C-C motif) receptor 20.092
Aicdaactivation-induced cytidine deaminase0.092
H2-M3histocompatibility 2, M region locus 30.091
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.087
Trim12atripartite motif-containing 12A0.085
Il1r1interleukin 1 receptor, type I0.085
Zfp36zinc finger protein 360.085
Ccl2chemokine (C-C motif) ligand 20.084
Pyhin1pyrin and HIN domain family, member 10.083
Il15rainterleukin 15 receptor, alpha chain0.080
Cdx2caudal type homeobox 20.080
Sfnstratifin0.079
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.014
Klrd1killer cell lectin-like receptor, subfamily D, member 10.012
Klra5killer cell lectin-like receptor, subfamily A, member 50.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism