The network for 'histone h4 k5 acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone h4 k5 acetylation

The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.

NameDescriptionProbabilityFunc Analog Organism
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.995
WDR5WD repeat domain 50.986
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.874
RBBP5retinoblastoma binding protein 50.657
HIST1H3Bhistone cluster 1, H3b0.543
TP53tumor protein p530.307
SMURF1SMAD specific E3 ubiquitin protein ligase 10.294
MYST1MYST histone acetyltransferase 10.204
DOT1LDOT1-like, histone H3 methyltransferase (S. cerevisiae)0.197
C20orf20chromosome 20 open reading frame 200.192
SIN3ASIN3 homolog A, transcription regulator (yeast)0.190
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.140
SETD1ASET domain containing 1A0.121
BARD1BRCA1 associated RING domain 10.113
FXR2fragile X mental retardation, autosomal homolog 20.104
VPS72vacuolar protein sorting 72 homolog (S. cerevisiae)0.101
DVL2dishevelled, dsh homolog 2 (Drosophila)0.082
MGEA5meningioma expressed antigen 5 (hyaluronidase)0.080
HCFC1host cell factor C1 (VP16-accessory protein)0.070
MYST2MYST histone acetyltransferase 20.070
SMAD1SMAD family member 10.058
MEN1multiple endocrine neoplasia I0.055
CHD8chromodomain helicase DNA binding protein 80.055
MED15mediator complex subunit 150.054
ING5inhibitor of growth family, member 50.052
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.050
INO80INO80 homolog (S. cerevisiae)0.048
SNAPINSNAP-associated protein0.048
MLL2myeloid/lymphoid or mixed-lineage leukemia 20.041
MESTmesoderm specific transcript homolog (mouse)0.038
DAXXdeath-domain associated protein0.038
CREBBPCREB binding protein0.036
TAF1DTATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa0.030
DMAP1DNA methyltransferase 1 associated protein 10.030
CEP70centrosomal protein 70kDa0.029
CCDC101coiled-coil domain containing 1010.029
CALCOCO2calcium binding and coiled-coil domain 20.029
USP42ubiquitin specific peptidase 420.028
CSNK2A2casein kinase 2, alpha prime polypeptide0.028
PAN3PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.027
THAP11THAP domain containing 110.027
IP6K2inositol hexakisphosphate kinase 20.026
UBE3Aubiquitin protein ligase E3A0.026
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.026
RBM23RNA binding motif protein 230.025
CXXC1CXXC finger protein 10.024
ZCCHC8zinc finger, CCHC domain containing 80.024
INO80EINO80 complex subunit E0.024
WDR82WD repeat domain 820.024
NQO1NAD(P)H dehydrogenase, quinone 10.023
PAPD7PAP associated domain containing 70.022
TP53BP1tumor protein p53 binding protein 10.021
ARIH2ariadne homolog 2 (Drosophila)0.020
SENP3SUMO1/sentrin/SMT3 specific peptidase 30.020
ZNF420zinc finger protein 4200.018
ZBTB8Azinc finger and BTB domain containing 8A0.018
PHC2polyhomeotic homolog 2 (Drosophila)0.018
CDK11Bcyclin-dependent kinase 11B0.018
ARandrogen receptor0.017
MAD2L1BPMAD2L1 binding protein0.017
CREBZFCREB/ATF bZIP transcription factor0.017
DPCDdeleted in primary ciliary dyskinesia homolog (mouse)0.016
PLEKHF2pleckstrin homology domain containing, family F (with FYVE domain) member 20.016
PAXIP1PAX interacting (with transcription-activation domain) protein 10.016
TADA3transcriptional adaptor 30.016
CCDC14coiled-coil domain containing 140.016
SYVN1synovial apoptosis inhibitor 1, synoviolin0.016
ZBTB17zinc finger and BTB domain containing 170.015
RASSF1Ras association (RalGDS/AF-6) domain family member 10.015
MBIPMAP3K12 binding inhibitory protein 10.015
MKRN1makorin ring finger protein 10.015
MSL2male-specific lethal 2 homolog (Drosophila)0.015
EP300E1A binding protein p3000.015
SAP30Sin3A-associated protein, 30kDa0.015
FBXL15F-box and leucine-rich repeat protein 150.014
PIP4K2Bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.014
YTHDF1YTH domain family, member 10.014
HIST2H3Chistone cluster 2, H3c0.014
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.014
POLBpolymerase (DNA directed), beta0.014
MLL4myeloid/lymphoid or mixed-lineage leukemia 40.013
C19orf50chromosome 19 open reading frame 500.013
SEPT8septin 80.013
PPFIA1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 10.013
KAT5K(lysine) acetyltransferase 50.013
ING4inhibitor of growth family, member 40.013
KDM2Alysine (K)-specific demethylase 2A0.012
TRAF4TNF receptor-associated factor 40.012
PLEKHO1pleckstrin homology domain containing, family O member 10.012
TRRAPtransformation/transcription domain-associated protein0.012
TNRC6Btrinucleotide repeat containing 6B0.012
SETD1BSET domain containing 1B0.012
HIST1H4Fhistone cluster 1, H4f0.012
ASXL1additional sex combs like 1 (Drosophila)0.012
RFWD2ring finger and WD repeat domain 20.012
ING2inhibitor of growth family, member 20.012
VEZTvezatin, adherens junctions transmembrane protein0.011
BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism