The network for 'cellular response to fatty acid' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to fatty acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.

NameDescriptionProbabilityFunc Analog Organism
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.532
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.403
FYNFYN oncogene related to SRC, FGR, YES0.388
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.270
CKS1BCDC28 protein kinase regulatory subunit 1B0.144
GRB2growth factor receptor-bound protein 20.133
HNF4Ahepatocyte nuclear factor 4, alpha0.122
S100BS100 calcium binding protein B0.118
IL1RAPinterleukin 1 receptor accessory protein0.104
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.094
NME1non-metastatic cells 1, protein (NM23A) expressed in0.074
NME3non-metastatic cells 3, protein expressed in0.073
CDK2cyclin-dependent kinase 20.071
ALDH1A1aldehyde dehydrogenase 1 family, member A10.067
IL1R1interleukin 1 receptor, type I0.067
CCNE1cyclin E10.053
FDPSfarnesyl diphosphate synthase0.050
NME4non-metastatic cells 4, protein expressed in0.039
ESRRGestrogen-related receptor gamma0.039
SGK3serum/glucocorticoid regulated kinase family, member 30.024
CAV1caveolin 1, caveolae protein, 22kDa0.022
ARID1AAT rich interactive domain 1A (SWI-like)0.019
ACACAacetyl-CoA carboxylase alpha0.017
E2F4E2F transcription factor 4, p107/p130-binding0.017
MUC1mucin 1, cell surface associated0.016
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.015
BCAR1breast cancer anti-estrogen resistance 10.015
PKMYT1protein kinase, membrane associated tyrosine/threonine 10.012
IL1RNinterleukin 1 receptor antagonist0.012
CDK1cyclin-dependent kinase 10.012
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.011
MED15mediator complex subunit 150.011
SCDstearoyl-CoA desaturase (delta-9-desaturase)0.011
FDFT1farnesyl-diphosphate farnesyltransferase 10.010
MLLT6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 60.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
vcanaversican a0.212
rbp4retinol binding protein 4, plasma0.186
fgfr2fibroblast growth factor receptor 20.170
otx2orthodenticle homolog 20.130
otx1borthodenticle homolog 1b0.127
six3asine oculis homeobox homolog 3a0.110
fzd7bfrizzled homolog 7b0.091
raraaretinoic acid receptor, alpha a0.082
rx3retinal homeobox gene 30.080
six3bsine oculis homeobox homolog 3b0.075
mdkbmidkine-related growth factor b0.070
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.058
mcoln1mucolipin 10.057
tbx2bT-box 2b0.053
efnb2aephrin B2a0.053
fgf8afibroblast growth factor 8 a0.050
igfbp6ainsulin-like growth factor binding protein 6a0.049
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.045
spry4sprouty (Drosophila) homolog 40.045
mbnl2muscleblind-like 2 (Drosophila)0.045
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.044
sox2SRY-box containing gene 20.042
ca2carbonic anhydrase II0.042
fabp11afatty acid binding protein 11a0.040
nkx2.2aNK2 transcription factor related 2a0.037
hmx4H6 family homeobox 40.037
foxa3forkhead box A30.037
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.036
pax6bpaired box gene 6b0.035
gfergrowth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)0.034
pitx3paired-like homeodomain transcription factor 30.034
ef1aelongation factor 1-alpha0.033
wif1wnt inhibitory factor 10.032
LOC100003330melanocortin-2 receptor accessory protein 2-like0.029
metmet proto-oncogene (hepatocyte growth factor receptor)0.028
ptger4aprostaglandin E receptor 4 (subtype EP4) a0.028
lgals3llectin, galactoside-binding, soluble, 3 (galectin 3)-like0.028
rlbp1aretinaldehyde binding protein 1a0.028
ugt1b1UDP glucuronosyltransferase 1 family, polypeptide B10.025
slc3a2solute carrier family 3, member 20.025
prox1prospero-related homeobox gene 10.024
fbln4fibulin 40.024
crabp2acellular retinoic acid binding protein 2, a0.024
pck2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.024
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.024
her6hairy-related 60.023
gata3GATA-binding protein 30.021
rab11fip4aRAB11 family interacting protein 4 (class II) a0.020
ptch2patched 20.020
mnx1motor neuron and pancreas homeobox 10.020
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.019
rarabretinoic acid receptor, alpha b0.019
btg1B-cell translocation gene 10.019
adrb2aadrenergic receptor, beta 2a0.019
myh11amyosin, heavy polypeptide 11, smooth muscle a0.019
celf1cugbp, Elav-like family member 10.019
ntn2netrin 20.018
pglyrp5peptidoglycan recognition protein 50.018
lats1LATS, large tumor suppressor, homolog 1 (Drosophila)0.018
ghrlghrelin/obestatin preprohormone0.018
mgaMAX gene associated0.017
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.017
slc39a1solute carrier family 39 (zinc transporter), member 10.017
wnt8awingless-type MMTV integration site family, member 8a0.016
lsrlipolysis stimulated lipoprotein receptor0.016
sat1aspermidine/spermine N1-acetyltransferase 1a0.016
idh1isocitrate dehydrogenase 1 (NADP+), soluble0.016
has2hyaluronan synthase 20.016
keap1akelch-like ECH-associated protein 1a0.016
ppdpfapancreatic progenitor cell differentiation and proliferation factor a0.016
ptgs2aprostaglandin-endoperoxide synthase 2a0.016
mbnl1muscleblind-like (Drosophila)0.015
slc16a1solute carrier family 16 (monocarboxylic acid transporters), member 10.015
pomt2protein-O-mannosyltransferase 20.015
fn1fibronectin 10.015
gamtguanidinoacetate N-methyltransferase0.015
rasl11bRAS-like, family 11, member B0.014
gli2aGLI-Kruppel family member GLI2a0.014
bhmtbetaine-homocysteine methyltransferase0.014
nusap1nucleolar and spindle associated protein 10.014
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.014
clic4chloride intracellular channel 40.013
gartphosphoribosylglycinamide formyltransferase0.013
pax6apaired box gene 6a0.013
anxa5bannexin A5b0.013
pinx1pin2/trf1-interacting protein 10.013
igfbp6binsulin-like growth factor binding protein 6b0.013
rassf7bRas association (RalGDS/AF-6) domain family (N-terminal) member 7b0.013
e2f5E2F transcription factor 50.013
rxrgaretinoid x receptor, gamma a0.013
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.013
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.048
Trp53transformation related protein 530.046
Ppargperoxisome proliferator activated receptor gamma0.037
Leprleptin receptor0.026
Ptk2PTK2 protein tyrosine kinase 20.025
Sfrp2secreted frizzled-related protein 20.022
Nos1nitric oxide synthase 1, neuronal0.021
Cav1caveolin 1, caveolae protein0.020
Fasnfatty acid synthase0.018
Ep300E1A binding protein p3000.018
Adipoqadiponectin, C1Q and collagen domain containing0.017
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.014
Hprthypoxanthine guanine phosphoribosyl transferase0.012
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.012
Neurod1neurogenic differentiation 10.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Idi1isopentenyl-diphosphate delta isomerase 10.781
Fdpsfarnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)0.597
Hmgcr3-hydroxy-3-methylglutaryl-Coenzyme A reductase0.319
Sc4molsterol-C4-methyl oxidase-like0.217
Cyp51cytochrome P450, family 510.207
Sqlesqualene epoxidase0.153
Fdft1farnesyl diphosphate farnesyl transferase 10.093
Insig1insulin induced gene 10.053
Acat3acetyl-Coenzyme A acetyltransferase 30.033
FosFBJ osteosarcoma oncogene0.033
Dad1defender against cell death 10.032
Btg2BTG family, member 20.032
Nhp2NHP2 ribonucleoprotein homolog (yeast)0.026
Cpt1acarnitine palmitoyltransferase 1a, liver0.024
Fasnfatty acid synthase0.021
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)0.020
Junbjun B proto-oncogene0.020
Nme1non-metastatic cells 1, protein (NM23A) expressed in0.020
Atf3activating transcription factor 30.020
Dusp1dual specificity phosphatase 10.018
Mvdmevalonate (diphospho) decarboxylase0.018
Il1ainterleukin 1 alpha0.017
Aqp7aquaporin 70.017
Dhcr2424-dehydrocholesterol reductase0.016
Zfp36zinc finger protein 360.016
Ptprcprotein tyrosine phosphatase, receptor type, C0.015
Ephx1epoxide hydrolase 1, microsomal0.015
Gstm2glutathione S-transferase mu 20.015
Cybbcytochrome b-245, beta polypeptide0.014
Lsslanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)0.014
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.014
Ctsccathepsin C0.013
Dhcr77-dehydrocholesterol reductase0.013
Ghrgrowth hormone receptor0.012
Egr1early growth response 10.012
Plcb2phospholipase C, beta 20.012
AclyATP citrate lyase0.011
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)0.011
Il1binterleukin 1 beta0.011
Glud1glutamate dehydrogenase 10.011
Top2atopoisomerase (DNA) II alpha0.011
Slco2a1solute carrier organic anion transporter family, member 2a10.010
Ptpn6protein tyrosine phosphatase, non-receptor type 60.010
Abp1amiloride binding protein 1 (amine oxidase, copper-containing)0.010
Abhd14babhydrolase domain containing 14b0.010
Postnperiostin, osteoblast specific factor0.010
Bckdhabranched chain ketoacid dehydrogenase E1, alpha polypeptide0.010
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.010
CblCas-Br-M (murine) ecotropic retroviral transforming sequence0.010
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism