The network for 'positive chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive chemotaxis

The directed movement of a motile cell or organism towards a higher concentration of a chemical.

NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.978
FGFR2fibroblast growth factor receptor 20.966
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.963
VEGFAvascular endothelial growth factor A0.949
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.920
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.920
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.883
TEKTEK tyrosine kinase, endothelial0.852
CCR5chemokine (C-C motif) receptor 50.797
DPP4dipeptidyl-peptidase 40.796
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.722
METmet proto-oncogene (hepatocyte growth factor receptor)0.676
PLCG1phospholipase C, gamma 10.661
FGFR1fibroblast growth factor receptor 10.650
PTPN1protein tyrosine phosphatase, non-receptor type 10.580
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.567
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.560
LATlinker for activation of T cells0.549
IL8interleukin 80.548
FGF1fibroblast growth factor 1 (acidic)0.546
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.520
PTPRCprotein tyrosine phosphatase, receptor type, C0.474
SEMA4Asema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A0.373
CXCL2chemokine (C-X-C motif) ligand 20.370
CDH5cadherin 5, type 2 (vascular endothelium)0.369
GAB1GRB2-associated binding protein 10.348
NRP1neuropilin 10.317
CXCL3chemokine (C-X-C motif) ligand 30.307
CXCL10chemokine (C-X-C motif) ligand 100.296
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.282
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.235
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.224
CCL8chemokine (C-C motif) ligand 80.223
CCL2chemokine (C-C motif) ligand 20.222
CTNND1catenin (cadherin-associated protein), delta 10.217
PLXNB1plexin B10.211
CXCL9chemokine (C-X-C motif) ligand 90.178
CCL5chemokine (C-C motif) ligand 50.172
NTRK2neurotrophic tyrosine kinase, receptor, type 20.157
BMPR1Abone morphogenetic protein receptor, type IA0.148
FN1fibronectin 10.143
CCL20chemokine (C-C motif) ligand 200.141
GRB7growth factor receptor-bound protein 70.130
NTRK1neurotrophic tyrosine kinase, receptor, type 10.128
CXCL11chemokine (C-X-C motif) ligand 110.125
CALCOCO2calcium binding and coiled-coil domain 20.119
CCL4chemokine (C-C motif) ligand 40.118
CNKSR2connector enhancer of kinase suppressor of Ras 20.114
APCadenomatous polyposis coli0.114
PTPRJprotein tyrosine phosphatase, receptor type, J0.111
DSG2desmoglein 20.111
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.107
SOS1son of sevenless homolog 1 (Drosophila)0.105
FGF10fibroblast growth factor 100.105
RND1Rho family GTPase 10.105
GHRgrowth hormone receptor0.099
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.096
IL6interleukin 6 (interferon, beta 2)0.094
FGAfibrinogen alpha chain0.093
TGIF1TGFB-induced factor homeobox 10.090
GAS6growth arrest-specific 60.089
CCL19chemokine (C-C motif) ligand 190.086
CCL3chemokine (C-C motif) ligand 30.079
CAV1caveolin 1, caveolae protein, 22kDa0.075
IL1Binterleukin 1, beta0.071
PLAUplasminogen activator, urokinase0.068
VCAM1vascular cell adhesion molecule 10.066
PLATplasminogen activator, tissue0.065
PGFplacental growth factor0.064
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.064
FGF7fibroblast growth factor 70.062
CCR7chemokine (C-C motif) receptor 70.062
PDGFCplatelet derived growth factor C0.061
PTGISprostaglandin I2 (prostacyclin) synthase0.061
CSNK1A1casein kinase 1, alpha 10.061
CCL7chemokine (C-C motif) ligand 70.060
CCR2chemokine (C-C motif) receptor 20.059
S100BS100 calcium binding protein B0.051
DPYSL4dihydropyrimidinase-like 40.050
CXCL5chemokine (C-X-C motif) ligand 50.050
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.049
CXCL13chemokine (C-X-C motif) ligand 130.048
CCR1chemokine (C-C motif) receptor 10.047
PLXND1plexin D10.046
SHC2SHC (Src homology 2 domain containing) transforming protein 20.044
UBDubiquitin D0.042
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.042
MMP12matrix metallopeptidase 12 (macrophage elastase)0.042
ANGPT2angiopoietin 20.041
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.041
PLXNB2plexin B20.040
PDGFAplatelet-derived growth factor alpha polypeptide0.040
CCL13chemokine (C-C motif) ligand 130.039
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.039
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.037
CCL14chemokine (C-C motif) ligand 140.037
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.037
IFNGinterferon, gamma0.036
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
daf-11Protein DAF-110.282
odr-3Protein ODR-30.249
tax-4Protein TAX-40.152
egl-18Protein EGL-180.122
che-1Protein CHE-10.104
tax-2Protein TAX-20.091
odr-1Protein ODR-10.076
flt-1Protein FLT-10.054
osm-3Protein OSM-30.048
cam-1Protein CAM-10.047
let-19Protein LET-190.045
sli-1Protein SLI-10.043
gcy-22Protein GCY-220.043
hlh-2Protein HLH-20.040
sel-12Protein SEL-120.040
elt-6Protein ELT-60.036
ttyh-1Protein TTYH-10.032
CELE_F25B4.2Protein F25B4.20.030
vab-1Protein VAB-10.030
daf-1Protein DAF-10.029
F13E6.1Protein F13E6.10.028
che-3Protein CHE-30.027
daf-7Protein DAF-70.023
F21A10.2Protein F21A10.20.022
nhr-67Protein NHR-670.021
cnd-1Protein CND-10.021
kvs-2Protein KVS-20.018
CELE_ZK682.2Protein ZK682.20.018
R148.5Protein R148.50.017
F28F5.4Protein F28F5.40.017
CELE_F53C11.4Protein F53C11.40.017
pqn-65Protein PQN-650.016
dpy-27Protein DPY-270.016
lin-25Protein LIN-250.016
tbb-4Protein TBB-40.016
Y110A7A.4Protein Y110A7A.40.016
CELE_C08H9.7Protein C08H9.70.016
pek-1Protein PEK-10.015
grk-2Protein GRK-20.015
K07E3.1Protein K07E3.10.014
col-105Protein COL-1050.014
lin-12Protein LIN-120.014
gap-2Protein GAP-20.014
daf-2Protein DAF-20.014
cpx-2Protein CPX-20.014
F54C9.7Protein F54C9.70.013
atf-6Protein ATF-60.013
nhr-4Protein NHR-40.013
C56G2.3Protein C56G2.30.013
CELE_C38C3.4Protein C38C3.40.013
nhr-189Protein NHR-1890.013
C06G1.2Protein C06G1.20.012
mig-2Protein MIG-20.012
nhr-6Protein NHR-60.012
ZK792.4Protein ZK792.40.012
ten-1Protein TEN-10.012
flh-2Protein FLH-20.012
col-56Protein COL-560.012
egl-46Protein EGL-460.012
swan-2Protein SWAN-20.012
C06G3.6Protein C06G3.60.012
eor-2Protein EOR-20.012
C32C4.3Protein C32C4.30.012
pup-2Protein PUP-20.012
lag-2Protein LAG-20.011
sax-3Protein SAX-30.011
dop-5Protein DOP-50.011
srbc-22Protein SRBC-220.011
bar-1Protein BAR-10.011
F35A5.4Protein F35A5.40.011
syg-1Protein SYG-10.011
tag-232Protein TAG-2320.011
che-2Protein CHE-20.011
pptr-2Protein PPTR-20.011
pat-3Protein PAT-30.011
ets-4Protein ETS-40.010
F52G3.1Protein F52G3.10.010
F16A11.1Protein F16A11.10.010
spat-3Protein SPAT-30.010
jac-1Protein JAC-10.010
R11.3Protein R11.30.010
set-16Protein SET-160.010
asic-1Protein ASIC-10.010
T23B3.6Protein T23B3.60.010
unc-7Protein UNC-70.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sema3dsemaphorin 3d0.289
aldh1a2aldehyde dehydrogenase 1 family, member A20.256
pea3ETS-domain transcription factor pea30.179
cdh5cadherin 50.161
kdrlkinase insert domain receptor like0.136
nrp2bneuropilin 2b0.131
meis1myeloid ecotropic viral integration 10.127
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.119
cdh2cadherin 2, neuronal0.113
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.096
cxcr4bchemokine (C-X-C motif), receptor 4b0.076
sulf1sulfatase 10.067
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.066
lef1lymphocyte enhancer binding factor 10.062
fgf3fibroblast growth factor 30.061
shhasonic hedgehog a0.059
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.059
notch3notch homolog 30.058
pcdh10bprotocadherin 10b0.052
mcambmelanoma cell adhesion molecule b0.051
hand2heart and neural crest derivatives expressed transcript 20.049
nr1h5nuclear receptor subfamily 1, group H, member 50.044
crip2cysteine-rich protein 20.042
epha4aeph receptor A4a0.039
plcg1phospholipase C, gamma 10.038
hmga1ahigh mobility group AT-hook 1a0.036
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.031
pax7bpaired box gene 7b0.031
hhiphedgehog interacting protein0.030
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.030
rhagRhesus blood group-associated glycoprotein0.029
tal1T-cell acute lymphocytic leukemia 10.029
bmp2bbone morphogenetic protein 2b0.028
vangl2vang-like 2 (van gogh, Drosophila)0.027
osr1odd-skipped related 1 (Drosophila)0.026
nrp2aneuropilin 2a0.025
lhx2bLIM homeobox 2b0.025
hmgb2bhigh-mobility group box 2b0.023
prdm16PR domain containing 160.022
gli2aGLI-Kruppel family member GLI2a0.022
akt2v-akt murine thymoma viral oncogene homolog 20.022
ptpn21protein tyrosine phosphatase, non-receptor type 210.021
hmgb1bhigh-mobility group box 1b0.021
olig2oligodendrocyte lineage transcription factor 20.020
ptprcprotein tyrosine phosphatase, receptor type, C0.020
gpc4glypican 40.020
grnagranulin a0.020
neo1neogenin 10.019
metmet proto-oncogene (hepatocyte growth factor receptor)0.019
lrrc33leucine rich repeat containing 330.018
myod1myogenic differentiation 10.018
h3f3aH3 histone, family 3A0.017
shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.017
nr2f2nuclear receptor subfamily 2, group F, member 20.016
vegfaavascular endothelial growth factor Aa0.016
hlxb9lbhomeo box HB9 like b0.016
enpp6ectonucleotide pyrophosphatase/phosphodiesterase 60.016
fgfr3fibroblast growth factor receptor 30.016
ptch2patched 20.015
kitakit receptor a0.014
tfectranscription factor EC0.014
sulf2lsulfatase 2, like0.014
rdh1retinol dehydrogenase 10.014
vsg1vessel-specific 10.013
hgfbhepatocyte growth factor b0.013
stat3signal transduction and activation of transcription 30.013
hmgb3ahigh-mobility group box 3a0.013
suv420h2suppressor of variegation 4-20 homolog 2 (Drosophila)0.012
kal1bKallmann syndrome 1b sequence0.012
restRE1-silencing transcription factor0.012
mrc1amannose receptor, C type 1a0.012
tie2endothelium-specific receptor tyrosine kinase 20.011
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.011
fevFEV (ETS oncogene family)0.011
tcf7l1btranscription factor 7-like 1b (T-cell specific, HMG-box)0.011
flt4fms-related tyrosine kinase 40.011
foxc1bforkhead box C1b0.011
fgf8afibroblast growth factor 8 a0.011
lama1laminin, alpha 10.011
ptpraprotein tyrosine phosphatase, receptor type, A0.011
bocbrother of CDO0.011
epb41l5erythrocyte membrane protein band 4.1 like 50.010
prdm14PR domain containing 140.010
s1pr2sphingosine-1-phosphate receptor 20.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
robo3CG5423 gene product from transcript CG5423-RA0.039
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.039
jingCG9397 gene product from transcript CG9397-RI0.033
trioCG18214 gene product from transcript CG18214-RA0.027
MrtfMyocardin-related transcription factor0.018
stumpsCG31317 gene product from transcript CG31317-RC0.018
reporeversed polarity0.017
plexBplexin B0.017
hipkhomeodomain interacting protein kinase0.017
Trim9CG31721 gene product from transcript CG31721-RB0.015
CG9650CG9650 gene product from transcript CG9650-RG0.014
Gbeta76CG protein beta-subunit 76C0.013
spensplit ends0.013
form3formin 30.013
SasSialic acid phosphate synthase0.013
ninaCneither inactivation nor afterpotential C0.012
S6kRPS6-p70-protein kinase0.012
inaDinactivation no afterpotential D0.011
zfh1Zn finger homeodomain 10.011
DadDaughters against dpp0.011
CG3371CG3371 gene product from transcript CG3371-RA0.011
Zasp66Z band alternatively spliced PDZ-motif protein 660.011
Gycalpha99BGuanylyl cyclase alpha-subunit at 99B0.011
Fas3Fasciclin 30.011
Pvf2PDGF- and VEGF-related factor 20.010
mewmultiple edematous wings0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgf8fibroblast growth factor 80.597
Slit3slit homolog 3 (Drosophila)0.567
Kdrkinase insert domain protein receptor0.465
Flt4FMS-like tyrosine kinase 40.404
Nos3nitric oxide synthase 3, endothelial cell0.337
Pecam1platelet/endothelial cell adhesion molecule 10.275
Flt1FMS-like tyrosine kinase 10.255
Gli3GLI-Kruppel family member GLI30.198
Pax3paired box gene 30.197
Plxnd1plexin D10.187
Tcf21transcription factor 210.171
Gab1growth factor receptor bound protein 2-associated protein 10.166
Fgfr2fibroblast growth factor receptor 20.156
Gli2GLI-Kruppel family member GLI20.137
Ldb3LIM domain binding 30.122
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.106
Slit2slit homolog 2 (Drosophila)0.100
Meox2mesenchyme homeobox 20.081
Mertkc-mer proto-oncogene tyrosine kinase0.076
Rarbretinoic acid receptor, beta0.074
Gli1GLI-Kruppel family member GLI10.073
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.070
Ptprbprotein tyrosine phosphatase, receptor type, B0.068
Notch2Notch gene homolog 2 (Drosophila)0.066
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.066
Retret proto-oncogene0.065
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.063
Zfpm2zinc finger protein, multitype 20.060
Acvr1activin A receptor, type 10.060
Edn3endothelin 30.057
Nkx2-1NK2 homeobox 10.056
Cxcl12chemokine (C-X-C motif) ligand 120.054
Nf2neurofibromatosis 20.054
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.054
Plcd1phospholipase C, delta 10.053
Ednraendothelin receptor type A0.052
Irs1insulin receptor substrate 10.052
Bdnfbrain derived neurotrophic factor0.052
Robo2roundabout homolog 2 (Drosophila)0.051
Sox18SRY-box containing gene 180.050
Acvrl1activin A receptor, type II-like 10.049
Akt1thymoma viral proto-oncogene 10.046
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.045
Pou3f3POU domain, class 3, transcription factor 30.044
Cdh5cadherin 50.042
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.041
Tekendothelial-specific receptor tyrosine kinase0.041
Tsc1tuberous sclerosis 10.041
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.040
AxlAXL receptor tyrosine kinase0.040
Cxcr4chemokine (C-X-C motif) receptor 40.038
Htr75-hydroxytryptamine (serotonin) receptor 70.038
Icam2intercellular adhesion molecule 20.037
Phox2bpaired-like homeobox 2b0.037
Gata6GATA binding protein 60.036
Wt1Wilms tumor 1 homolog0.034
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.034
Gata4GATA binding protein 40.033
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.033
Dnajb5DnaJ (Hsp40) homolog, subfamily B, member 50.033
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.032
Pitx2paired-like homeodomain transcription factor 20.032
Rasgrp1RAS guanyl releasing protein 10.032
Ccl9chemokine (C-C motif) ligand 90.031
Shesrc homology 2 domain-containing transforming protein E0.031
Robo1roundabout homolog 1 (Drosophila)0.031
Tgfb2transforming growth factor, beta 20.030
Adcy4adenylate cyclase 40.030
Bmp5bone morphogenetic protein 50.029
Shhsonic hedgehog0.029
Ece1endothelin converting enzyme 10.029
Rararetinoic acid receptor, alpha0.028
Pcdh12protocadherin 120.028
Fli1Friend leukemia integration 10.028
Grin2cglutamate receptor, ionotropic, NMDA2C (epsilon 3)0.028
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.027
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.027
Smad7MAD homolog 7 (Drosophila)0.026
Tbx1T-box 10.026
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.026
Mesp1mesoderm posterior 10.026
Phox2apaired-like homeobox 2a0.026
Lcn2lipocalin 20.025
Gsg1germ cell-specific gene 10.025
Apbb2amyloid beta (A4) precursor protein-binding, family B, member 20.025
Matn4matrilin 40.025
Cntn4contactin 40.025
Bcl2B-cell leukemia/lymphoma 20.024
F10coagulation factor X0.024
Epha3Eph receptor A30.024
Smad3MAD homolog 3 (Drosophila)0.024
Twist2twist homolog 2 (Drosophila)0.024
Smosmoothened homolog (Drosophila)0.024
Sufusuppressor of fused homolog (Drosophila)0.024
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.024
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gna12guanine nucleotide binding protein (G protein) alpha 120.038
Edn1endothelin 10.028
Cd83CD83 molecule0.028
Fgfr2fibroblast growth factor receptor 20.025
Ptafrplatelet-activating factor receptor0.023
Adora2aadenosine A2a receptor0.022
Arandrogen receptor0.020
Ptmaprothymosin alpha0.016
Ucp3uncoupling protein 3 (mitochondrial, proton carrier)0.015
Pcnaproliferating cell nuclear antigen0.015
Il8rainterleukin 8 receptor, alpha0.014
Sf1splicing factor 10.014
Slco2a1solute carrier organic anion transporter family, member 2a10.012
Tgfbr2transforming growth factor, beta receptor II0.012
Hist1h1ahistone cluster 1, H1a0.011
Dgkgdiacylglycerol kinase, gamma0.011
Fgf7fibroblast growth factor 70.011
Vom2r44vomeronasal 2 receptor 440.011
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.011
Cst7cystatin F (leukocystatin)0.010
Il8rbinterleukin 8 receptor, beta0.010
Hckhemopoietic cell kinase0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism