The network for 'protein acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein acetylation

The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.

NameDescriptionProbabilityFunc Analog Organism
WDR5WD repeat domain 51.000
TP53tumor protein p531.000
CREBBPCREB binding protein1.000
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)1.000
TRRAPtransformation/transcription domain-associated protein0.999
KAT2AK(lysine) acetyltransferase 2A0.996
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.996
KAT2BK(lysine) acetyltransferase 2B0.995
C20orf20chromosome 20 open reading frame 200.992
JUNjun proto-oncogene0.989
TBPTATA box binding protein0.976
HDAC1histone deacetylase 10.973
SIN3ASIN3 homolog A, transcription regulator (yeast)0.972
DUSP1dual specificity phosphatase 10.969
ACTL6Aactin-like 6A0.966
SIRT1sirtuin 10.955
RUVBL2RuvB-like 2 (E. coli)0.953
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa0.947
USP22ubiquitin specific peptidase 220.930
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.919
MORF4L1mortality factor 4 like 10.901
MYST1MYST histone acetyltransferase 10.897
HDAC2histone deacetylase 20.891
CBX5chromobox homolog 50.885
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.879
TRIM28tripartite motif containing 280.866
RBBP5retinoblastoma binding protein 50.865
HCFC1host cell factor C1 (VP16-accessory protein)0.859
NCOA6nuclear receptor coactivator 60.845
VPS72vacuolar protein sorting 72 homolog (S. cerevisiae)0.843
YY1YY1 transcription factor0.828
HIST1H3Bhistone cluster 1, H3b0.819
TAL1T-cell acute lymphocytic leukemia 10.818
NCOA1nuclear receptor coactivator 10.808
RBBP4retinoblastoma binding protein 40.806
EP300E1A binding protein p3000.797
NCOA2nuclear receptor coactivator 20.791
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.791
DAXXdeath-domain associated protein0.785
HIST2H3Chistone cluster 2, H3c0.772
KAT5K(lysine) acetyltransferase 50.765
RBBP7retinoblastoma binding protein 70.762
RB1retinoblastoma 10.736
MEN1multiple endocrine neoplasia I0.727
IKBKAPinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein0.699
ARandrogen receptor0.684
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.684
MBIPMAP3K12 binding inhibitory protein 10.647
LNX1ligand of numb-protein X 10.613
ING3inhibitor of growth family, member 30.606
MRFAP1Morf4 family associated protein 10.595
CFL1cofilin 1 (non-muscle)0.591
EPC2enhancer of polycomb homolog 2 (Drosophila)0.584
ELP2elongation protein 2 homolog (S. cerevisiae)0.581
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.580
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.566
DOT1LDOT1-like, histone H3 methyltransferase (S. cerevisiae)0.564
CXXC1CXXC finger protein 10.559
SMAD7SMAD family member 70.542
MAGEA3melanoma antigen family A, 30.535
BCL9B-cell CLL/lymphoma 90.531
CHD8chromodomain helicase DNA binding protein 80.501
PAX3paired box 30.489
CCNT1cyclin T10.487
STAG2stromal antigen 20.483
NCOA3nuclear receptor coactivator 30.479
TADA3transcriptional adaptor 30.474
POLE3polymerase (DNA directed), epsilon 3 (p17 subunit)0.470
UBE3Aubiquitin protein ligase E3A0.467
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit0.453
ELP4elongation protein 4 homolog (S. cerevisiae)0.448
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.436
SETD7SET domain containing (lysine methyltransferase) 70.435
POU3F2POU class 3 homeobox 20.429
LMO4LIM domain only 40.427
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.426
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.425
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.421
NSMCE1non-SMC element 1 homolog (S. cerevisiae)0.417
PAXIP1PAX interacting (with transcription-activation domain) protein 10.417
NSMCE4Anon-SMC element 4 homolog A (S. cerevisiae)0.408
TAF3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa0.406
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.403
ELP3elongation protein 3 homolog (S. cerevisiae)0.391
GSK3Bglycogen synthase kinase 3 beta0.390
BRCA1breast cancer 1, early onset0.389
ATXN7ataxin 70.384
MAGEA12melanoma antigen family A, 120.371
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.371
POU5F1POU class 5 homeobox 10.370
RUNX1runt-related transcription factor 10.361
SKIv-ski sarcoma viral oncogene homolog (avian)0.353
CTAG1Bcancer/testis antigen 1B0.352
NAP1L5nucleosome assembly protein 1-like 50.346
MAGEA6melanoma antigen family A, 60.345
MAPK14mitogen-activated protein kinase 140.342
APPamyloid beta (A4) precursor protein0.339
ZNF496zinc finger protein 4960.334
ZNF148zinc finger protein 1480.331
VAC14Vac14 homolog (S. cerevisiae)0.329
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
hat1histone acetyltransferase 10.586
mcmbpminichromosome maintenance complex binding protein0.408
cse1lchromosome segregation 1-like (S. cerevisiae)0.396
ash2lash2 (absent, small, or homeotic)-like (Drosophila)0.375
myogmyogenin0.336
ep300bE1A binding protein p300 b0.324
zc4h2zinc finger, C4H2 domain containing0.311
mcrs1microspherule protein 10.299
naspnuclear autoantigenic sperm protein (histone-binding)0.293
ube2iubiquitin-conjugating enzyme E2I0.274
ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.236
hcfc1ahost cell factor C1a0.213
pola1polymerase (DNA directed), alpha 10.200
rbb4retinoblastoma binding protein 40.199
rpa1replication protein A10.199
fen1flap structure-specific endonuclease 10.198
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.192
gtf2f2ageneral transcription factor IIF, polypeptide 2a0.187
rpa2replication protein A20.185
anp32bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.184
phf16PHD finger protein 160.168
nktrnatural killer-tumor recognition sequence0.162
mta2metastasis associated 1 family, member 20.160
hirip3HIRA interacting protein 30.154
ipo9importin 90.153
rnf2ring finger protein 20.146
cbx5chromobox homolog 5 (HP1 alpha homolog, Drosophila)0.142
tal1T-cell acute lymphocytic leukemia 10.141
ccnt2bcyclin T2b0.141
pom121POM121 membrane glycoprotein (rat)0.140
hdac1histone deacetylase 10.139
prmt5protein arginine methyltransferase 50.138
cuedc2CUE domain containing 20.136
usp1ubiquitin specific protease 10.136
cops2COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)0.132
suv420h2suppressor of variegation 4-20 homolog 2 (Drosophila)0.131
ss18synovial sarcoma translocation, chromosome 18 (H. sapiens)0.128
myf5myogenic factor 50.128
ppm1dprotein phosphatase 1D magnesium-dependent, delta isoform0.127
lztfl1leucine zipper transcription factor-like 10.124
morf4l1mortality factor 4 like 10.124
si:dkey-145p14.5si:dkey-145p14.50.124
phf6PHD finger protein 60.120
pcdh2acprotocadherin 2 alpha c0.120
crestincrestin0.119
nop58NOP58 ribonucleoprotein homolog (yeast)0.115
brd3abromodomain containing 3a0.114
wu:fq41a10wu:fq41a100.112
zgc:73345zgc:733450.110
zgc:172056zgc:1720560.110
dcaf7ddb1 and cul4 associated factor 70.109
mycl1av-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) a0.109
lima1LIM domain and actin binding 10.108
rbb4lretinoblastoma binding protein 4, like0.108
uba3ubiquitin-like modifier activating enzyme 30.107
apex1APEX nuclease (multifunctional DNA repair enzyme) 10.107
ube2nbubiquitin-conjugating enzyme E2Nb0.105
prp19PRP19/PSO4 homolog (S. cerevisiae)0.104
pbrm1lpolybromo 1, like0.104
dedd1death effector domain-containing 10.103
mpped2metallophosphoesterase domain containing 20.102
gle1GLE1 RNA export mediator homolog (yeast)0.102
zc3h13zinc finger CCCH-type containing 130.101
tbpTATA box binding protein0.101
rad51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.100
mcm7MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)0.098
prdm2bPR domain containing 2, with ZNF domain b0.097
zgc:114097zgc:1140970.096
mpxmyeloid-specific peroxidase0.096
cpsf3cleavage and polyadenylation specific factor 30.096
whsc1Wolf-Hirschhorn syndrome candidate 10.094
taf1TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.093
rag1recombination activating gene 10.093
larsleucyl-tRNA synthetase0.092
hmgb3ahigh-mobility group box 3a0.091
zgc:100817zgc:1008170.090
bsgbasigin0.089
eif3jaeukaryotic translation initiation factor 3, subunit Ja0.089
zgc:65861zgc:658610.089
cops3COP9 constitutive photomorphogenic homolog subunit 30.088
hp1bp3heterochromatin protein 1, binding protein 30.088
chek1CHK1 checkpoint homolog (S. pombe)0.088
zgc:112083zgc:1120830.087
uck2buridine-cytidine kinase 2b0.087
rif1RAP1 interacting factor homolog (yeast)0.087
zgc:77155zgc:771550.086
si:dkeyp-22b2.3si:dkeyp-22b2.30.086
tnpo3transportin 30.085
LOC100534742UBX domain-containing protein 1-like0.085
supv3l1suppressor of var1, 3-like 1 (S. cerevisiae)0.085
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.085
ankra2ankyrin repeat, family A (RFXANK-like), 20.084
gins2GINS complex subunit 20.084
cbx2chromobox homolog 2 (Drosophila Pc class)0.084
kdm1alysine (K)-specific demethylase 1a0.084
ilf2interleukin enhancer binding factor 20.083
macf1microtubule-actin crosslinking factor 10.083
med4mediator complex subunit 40.082
mknk2bMAP kinase-interacting serine/threonine kinase 2b0.082
uba2ubiquitin-like modifier activating enzyme 20.082
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
dikdiskette1.000
CG10414CG10414 gene product from transcript CG10414-RA0.999
HcfHost cell factor0.983
D12CG13400 gene product from transcript CG13400-RA0.981
Snr1Snf5-related 10.968
Mocs2Molybdopterin synthase 20.931
wdswill die slowly0.914
dcodiscs overgrown0.889
PcafCG4107 gene product from transcript CG4107-RA0.858
Atac1ATAC component 10.850
Sir2CG5216 gene product from transcript CG5216-RA0.815
CTCFCG8591 gene product from transcript CG8591-RA0.763
Chrac-14CG13399 gene product from transcript CG13399-RA0.678
brmbrahma0.670
CG3363CG3363 gene product from transcript CG3363-RB0.619
mofmales absent on the first0.618
ash1absent, small, or homeotic discs 10.618
CG13298CG13298 gene product from transcript CG13298-RA0.602
Sgf29CG30390 gene product from transcript CG30390-RA0.592
His2AvHistone H2A variant0.577
msl-3male-specific lethal 30.574
panpangolin0.572
Saf6SAGA factor-like TAF60.566
Su(var)3-3Suppressor of variegation 3-30.551
msl-1male-specific lethal 10.551
Gap1GTPase-activating protein 10.536
Nipped-ACG33554 gene product from transcript CG33554-RE0.502
e(y)3enhancer of yellow 30.420
lwrlesswright0.407
CG10107CG10107 gene product from transcript CG10107-RA0.394
eggeggless0.384
NC2betaCG4185 gene product from transcript CG4185-RA0.376
SuURSuppressor of Under-Replication0.350
RgaRegena0.333
noinoisette0.312
Rpd3CG7471 gene product from transcript CG7471-RA0.306
mod(mdg4)modifier of mdg40.299
bonbonus0.299
KrKruppel0.291
Tao-1CG14217 gene product from transcript CG14217-RF0.287
O-fut1O-fucosyltransferase 10.283
domdomino0.275
Rpb4CG33520 gene product from transcript CG33520-RF0.267
dalaoCG7055 gene product from transcript CG7055-RA0.260
slp1sloppy paired 10.251
Eip75BEcdysone-induced protein 75B0.225
Nf-YBNuclear factor Y-box B0.213
snostrawberry notch0.210
waplwings apart-like0.209
ScmSex comb on midleg0.203
ChroChromator0.178
cyccycle0.178
GmdGDP-mannose 4,6-dehydratase0.175
ksrkinase suppressor of ras0.164
AblAbl tyrosine kinase0.152
CG3995CG3995 gene product from transcript CG3995-RA0.143
ushu-shaped0.141
CG11242CG11242 gene product from transcript CG11242-RA0.140
SRm160CG11274 gene product from transcript CG11274-RA0.139
l(2)37Cblethal (2) 37Cb0.136
gloglorund0.136
HandCG18144 gene product from transcript CG18144-RA0.135
Deaf1Deformed epidermal autoregulatory factor-10.130
Mfap1Microfibril-associated protein 10.129
cwoclockwork orange0.129
Ino80CG31212 gene product from transcript CG31212-RA0.122
Su(var)3-7Suppressor of variegation 3-70.121
CtBPC-terminal Binding Protein0.115
Cdc27CG8610 gene product from transcript CG8610-RA0.114
egreiger0.113
SelDSelenide,water dikinase0.112
CSN5COP9 complex homolog subunit 50.112
CG42672CG42672 gene product from transcript CG42672-RD0.112
Ada2bCG9638 gene product from transcript CG9638-RA0.110
pxplexus0.110
krzkurtz0.108
dbedribble0.107
alyalways early0.107
bynbrachyenteron0.107
Caf1-180CG12109 gene product from transcript CG12109-RB0.107
Aut1CG6877 gene product from transcript CG6877-RA0.106
Bap55Brahma associated protein 55kD0.103
CG9018CG9018 gene product from transcript CG9018-RA0.100
CG8443CG8443 gene product from transcript CG8443-RA0.099
bratbrain tumor0.098
pr-set7CG3307 gene product from transcript CG3307-RC0.096
simjsimjang0.095
Spt5CG7626 gene product from transcript CG7626-RA0.095
Su(z)2Suppressor of zeste 20.094
pzgputzig0.093
CG32343CG32343 gene product from transcript CG32343-RB0.092
Taf6TBP-associated factor 60.092
l(3)mbtlethal (3) malignant brain tumor0.090
SMC1CG6057 gene product from transcript CG6057-RA0.090
Su(H)Suppressor of Hairless0.087
CG16812CG16812 gene product from transcript CG16812-RA0.084
HLH54FCG5005 gene product from transcript CG5005-RA0.084
PcPolycomb0.083
Kap-alpha3karyopherin alpha30.083
MadMothers against dpp0.077
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tmsb4xthymosin beta 4, X-linked0.024
Cfl1cofilin 1, non-muscle0.022
Tuba1ctubulin, alpha 1C0.020
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.015
Casp2caspase 20.013
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.012
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.011
Ubbubiquitin B0.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ADA2Ada2p1.000
TRA1Tra1p1.000
HHT1Hht1p0.998
TAF6Taf6p0.998
NGG1Ngg1p0.991
SPT8Spt8p0.982
GCN5Gcn5p0.975
SUS1Sus1p0.947
HFI1Hfi1p0.946
TAF12Taf12p0.893
TAF10Taf10p0.869
YAF9Yaf9p0.868
SPT7Spt7p0.848
SGF29Sgf29p0.842
EAF1Eaf1p0.803
SPT20Spt20p0.739
TAF9Taf9p0.704
SGF11Sgf11p0.694
TAF5Taf5p0.669
MAK10Mak10p0.623
EPL1Epl1p0.609
EAF6Eaf6p0.609
YNG1Yng1p0.592
ARP4Arp4p0.591
BDF1Bdf1p0.521
ISW1Isw1p0.481
ASF1Asf1p0.480
RTT106Rtt106p0.468
RCO1Rco1p0.423
MAK31Mak31p0.396
EAF5Eaf5p0.386
HAT1Hat1p0.352
HAT2Hat2p0.290
HHT2Hht2p0.254
UBP8Ubp8p0.247
RSC2Rsc2p0.239
TAF3Taf3p0.233
RSC4Rsc4p0.219
SPT15Spt15p0.217
CKB1Ckb1p0.213
HIF1Hif1p0.206
CAC2Cac2p0.199
MAK3Mak3p0.196
SPT3Spt3p0.195
SWI1Swi1p0.188
SGF73Sgf73p0.181
RPD3Rpd3p0.178
YNG2Yng2p0.165
NTO1Nto1p0.157
EAF3Eaf3p0.151
TAF14Taf14p0.133
RFC5Rfc5p0.132
RTT109Rtt109p0.131
SWC4Swc4p0.126
SNF5Snf5p0.125
ESA1Esa1p0.117
SAS5Sas5p0.116
YAT1Yat1p0.114
ORC4Orc4p0.114
EAF7Eaf7p0.113
HIR2Hir2p0.113
HIR1Hir1p0.110
MOT1Mot1p0.104
TEC1Tec1p0.100
SWI5Swi5p0.099
SDC1Sdc1p0.092
SWD3Swd3p0.091
HHO1Hho1p0.090
YLR455Whypothetical protein0.085
BDF2Bdf2p0.077
SET2Set2p0.076
VPS75Vps75p0.075
ELP4Elp4p0.073
HHF2Hhf2p0.069
RLF2Rlf2p0.068
MSB1Msb1p0.067
KEM1Kem1p0.065
RSC30Rsc30p0.062
PFD1Pfd1p0.058
ORC3Orc3p0.057
IKI1Iki1p0.057
NOP10Nop10p0.056
TAF13Taf13p0.053
YHB1Yhb1p0.052
ARP8Arp8p0.052
CTF8Ctf8p0.051
HDA2Hda2p0.050
HPC2Hpc2p0.049
LEO1Leo1p0.049
DCC1Dcc1p0.049
YIR035Chypothetical protein0.048
SAS3Sas3p0.048
RPT6Rpt6p0.047
ELP6Elp6p0.047
MED1Med1p0.046
SWI3Swi3p0.046
ORC1Orc1p0.044
SUV3Suv3p0.044
NSA1Nsa1p0.043
SWC5Swc5p0.043