The network for 'macrophage chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macrophage chemotaxis

The movement of a macrophage in response to an external stimulus.

NameDescriptionProbabilityFunc Analog Organism
CCR5chemokine (C-C motif) receptor 50.974
CCL4chemokine (C-C motif) ligand 40.793
IL8interleukin 80.784
TGIF1TGFB-induced factor homeobox 10.587
CXCL9chemokine (C-X-C motif) ligand 90.575
CCL5chemokine (C-C motif) ligand 50.574
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.525
IL1Binterleukin 1, beta0.507
CXCL2chemokine (C-X-C motif) ligand 20.505
CCL2chemokine (C-C motif) ligand 20.470
FN1fibronectin 10.467
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.398
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.372
FYNFYN oncogene related to SRC, FGR, YES0.361
CCR1chemokine (C-C motif) receptor 10.321
CXCL3chemokine (C-X-C motif) ligand 30.312
CXCL10chemokine (C-X-C motif) ligand 100.286
IL6interleukin 6 (interferon, beta 2)0.258
CCL7chemokine (C-C motif) ligand 70.245
DPP4dipeptidyl-peptidase 40.235
CCL8chemokine (C-C motif) ligand 80.222
CCL13chemokine (C-C motif) ligand 130.165
CALCOCO2calcium binding and coiled-coil domain 20.158
TIMP1TIMP metallopeptidase inhibitor 10.123
IL7Rinterleukin 7 receptor0.102
TNFtumor necrosis factor0.102
IDEinsulin-degrading enzyme0.097
ICAM1intercellular adhesion molecule 10.092
CXCL11chemokine (C-X-C motif) ligand 110.083
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.083
IL10interleukin 100.082
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.079
CXCL5chemokine (C-X-C motif) ligand 50.077
MMP12matrix metallopeptidase 12 (macrophage elastase)0.076
PDCD6IPprogrammed cell death 6 interacting protein0.063
CCL19chemokine (C-C motif) ligand 190.061
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.061
CCL22chemokine (C-C motif) ligand 220.060
CD63CD63 molecule0.060
RABAC1Rab acceptor 1 (prenylated)0.057
VCAM1vascular cell adhesion molecule 10.056
CCL20chemokine (C-C motif) ligand 200.053
TNFAIP6tumor necrosis factor, alpha-induced protein 60.050
FLNAfilamin A, alpha0.050
CA12carbonic anhydrase XII0.050
AQP9aquaporin 90.049
PLAURplasminogen activator, urokinase receptor0.049
TGFB1transforming growth factor, beta 10.047
CH25Hcholesterol 25-hydroxylase0.047
CXCL13chemokine (C-X-C motif) ligand 130.046
TLN1talin 10.045
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.045
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.044
TNFRSF9tumor necrosis factor receptor superfamily, member 90.044
CTNND1catenin (cadherin-associated protein), delta 10.043
CCR7chemokine (C-C motif) receptor 70.038
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.036
S100A6S100 calcium binding protein A60.036
EMP3epithelial membrane protein 30.035
IFNGinterferon, gamma0.034
MICAMHC class I polypeptide-related sequence A0.033
S100A10S100 calcium binding protein A100.030
BCL2A1BCL2-related protein A10.029
INHBAinhibin, beta A0.029
S100A11S100 calcium binding protein A110.029
CCR4chemokine (C-C motif) receptor 40.026
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.025
LRRC41leucine rich repeat containing 410.025
BCAR1breast cancer anti-estrogen resistance 10.023
DUSP10dual specificity phosphatase 100.023
CCL11chemokine (C-C motif) ligand 110.022
S100A4S100 calcium binding protein A40.022
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.022
VSIG4V-set and immunoglobulin domain containing 40.021
CD83CD83 molecule0.020
C5AR1complement component 5a receptor 10.020
CCL3chemokine (C-C motif) ligand 30.020
SELEselectin E0.020
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.020
MESTmesoderm specific transcript homolog (mouse)0.020
IL2RBinterleukin 2 receptor, beta0.019
PTPN1protein tyrosine phosphatase, non-receptor type 10.019
TMSB10thymosin beta 100.019
LGALS1lectin, galactoside-binding, soluble, 10.018
SOCS3suppressor of cytokine signaling 30.018
TLR2toll-like receptor 20.018
CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39)0.017
MMP3matrix metallopeptidase 3 (stromelysin 1, progelatinase)0.017
CFBcomplement factor B0.017
METmet proto-oncogene (hepatocyte growth factor receptor)0.016
PLAUplasminogen activator, urokinase0.016
C2complement component 20.016
PTPREprotein tyrosine phosphatase, receptor type, E0.016
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.015
EDN1endothelin 10.015
IL1RNinterleukin 1 receptor antagonist0.015
RGS1regulator of G-protein signaling 10.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
csf1racolony stimulating factor 1 receptor, a0.993
mpxmyeloid-specific peroxidase0.900
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.880
mmp9matrix metalloproteinase 90.865
fli1afriend leukemia integration 1a0.808
col12a1collagen, type XII, alpha 10.716
fli1bfriend leukemia integration 1b0.552
sox7SRY-box containing gene 70.525
etv2ets variant gene 20.522
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.509
cdh5cadherin 50.491
tie1endothelium-specific receptor tyrosine kinase 10.465
kdrlkinase insert domain receptor like0.465
yrkYes-related kinase0.443
csf3rcolony stimulating factor 3 receptor (granulocyte)0.427
gfi1.1growth factor independent 1.10.408
runx1runt-related transcription factor 10.379
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.311
ncf1neutrophil cytosolic factor 10.271
tie2endothelium-specific receptor tyrosine kinase 20.264
mitfamicrophthalmia-associated transcription factor a0.250
lcp1lymphocyte cytosolic plastin 10.249
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.244
mmp13amatrix metalloproteinase 13a0.192
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.186
hbbe1.1hemoglobin beta embryonic-1.10.177
vegfaavascular endothelial growth factor Aa0.163
dll4delta-like 4 (Drosophila)0.160
tal1T-cell acute lymphocytic leukemia 10.149
flt4fms-related tyrosine kinase 40.139
coro1acoronin, actin binding protein, 1A0.138
sgk1serum/glucocorticoid regulated kinase 10.134
mmp2matrix metalloproteinase 20.125
spi1lspleen focus forming virus (SFFV) proviral integration oncogene spi1 like0.123
dusp5dual specificity phosphatase 50.115
btkBruton agammaglobulinemia tyrosine kinase0.111
esamaendothelial cell adhesion molecule a0.100
plxnd1plexin D10.098
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.093
col5a2lcollagen, type V, alpha 2-like0.082
lrrc33leucine rich repeat containing 330.081
fmnl2aformin-like 2a0.080
hspg2heparan sulfate proteoglycan 20.078
mmp14bmatrix metalloproteinase 14b (membrane-inserted)0.074
gata1aGATA binding protein 1a0.072
timp2atissue inhibitor of metalloproteinase 2a0.067
arap3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 30.062
atoh8atonal homolog 80.061
cnn2calponin 20.061
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.057
ahr2aryl hydrocarbon receptor 20.052
ptprcprotein tyrosine phosphatase, receptor type, C0.050
stx11asyntaxin 11a0.050
efnb2aephrin B2a0.050
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.049
hbae1hemoglobin alpha embryonic-10.049
ctgfconnective tissue growth factor0.047
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.047
vsg1vessel-specific 10.046
lsrlipolysis stimulated lipoprotein receptor0.046
myd88myeloid differentiation primary response gene (88)0.045
pnp4apurine nucleoside phosphorylase 4a0.045
rhogbras homolog gene family, member Gb0.043
stab2stabilin 20.040
sox10SRY-box containing gene 100.040
mcambmelanoma cell adhesion molecule b0.040
col5a1procollagen, type V, alpha 10.040
cald1caldesmon 10.040
ccl25bchemokine (C-C motif) ligand 25b0.039
gmfgglia maturation factor, gamma0.039
LOC566752hypothetical protein LOC5667520.038
ntn4netrin 40.036
dab2disabled homolog 2 (Drosophila)0.036
ptpn6protein tyrosine phosphatase, non-receptor type 60.035
elmo1engulfment and cell motility 1 (ced-12 homolog, C. elegans)0.034
fevFEV (ETS oncogene family)0.033
LOC100151049lysosomal-associated protein transmembrane 50.033
metap2methionyl aminopeptidase 20.032
cdh23cadherin-like 230.032
col1a2collagen, type I, alpha 20.032
acvrl1activin A receptor type II-like 10.031
fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.030
cyp1acytochrome P450, family 1, subfamily A0.029
aox3aldehyde oxidase 30.029
agtr2angiotensin II receptor, type 20.028
pak2ap21 (CDKN1A)-activated kinase 2a0.028
samsn1aSAM domain, SH3 domain and nuclear localisation signals, 1a0.027
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccr2chemokine (C-C motif) receptor 20.995
Ccl2chemokine (C-C motif) ligand 20.935
Ccr1chemokine (C-C motif) receptor 10.793
Ccl3chemokine (C-C motif) ligand 30.711
Il1binterleukin 1 beta0.518
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.496
Fcgr1Fc receptor, IgG, high affinity I0.484
Selpselectin, platelet0.469
Csf1colony stimulating factor 1 (macrophage)0.467
Itgaxintegrin alpha X0.448
Il1rninterleukin 1 receptor antagonist0.431
Ccr5chemokine (C-C motif) receptor 50.370
Cd44CD44 antigen0.293
Ccl4chemokine (C-C motif) ligand 40.264
Lyz2lysozyme 20.244
Msr1macrophage scavenger receptor 10.191
Ccl9chemokine (C-C motif) ligand 90.178
Cxcr2chemokine (C-X-C motif) receptor 20.170
C3ar1complement component 3a receptor 10.167
Ccl7chemokine (C-C motif) ligand 70.156
S100a8S100 calcium binding protein A8 (calgranulin A)0.141
Cxcl13chemokine (C-X-C motif) ligand 130.140
Ccl17chemokine (C-C motif) ligand 170.125
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.118
Irg1immunoresponsive gene 10.106
Clec4dC-type lectin domain family 4, member d0.105
C5ar1complement component 5a receptor 10.097
Il1ainterleukin 1 alpha0.097
Ccl8chemokine (C-C motif) ligand 80.094
S100a9S100 calcium binding protein A9 (calgranulin B)0.093
Mmp8matrix metallopeptidase 80.091
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.086
Clec4eC-type lectin domain family 4, member e0.084
Has1hyaluronan synthase10.083
Ch25hcholesterol 25-hydroxylase0.081
Loxlysyl oxidase0.081
Ifnginterferon gamma0.079
Slfn1schlafen 10.078
Mmp3matrix metallopeptidase 30.077
Cd180CD180 antigen0.076
Ear2eosinophil-associated, ribonuclease A family, member 20.075
Ccl6chemokine (C-C motif) ligand 60.073
Cd96CD96 antigen0.072
Fpr2formyl peptide receptor 20.072
Cxcl2chemokine (C-X-C motif) ligand 20.070
Clec4a2C-type lectin domain family 4, member a20.069
Mmp12matrix metallopeptidase 120.069
Ifitm6interferon induced transmembrane protein 60.067
Batfbasic leucine zipper transcription factor, ATF-like0.065
Klrk1killer cell lectin-like receptor subfamily K, member 10.064
Folr2folate receptor 2 (fetal)0.063
Cd40CD40 antigen0.063
Aoahacyloxyacyl hydrolase0.062
SrcRous sarcoma oncogene0.062
BtkBruton agammaglobulinemia tyrosine kinase0.061
Slfn4schlafen 40.061
Ncr1natural cytotoxicity triggering receptor 10.060
Mmp9matrix metallopeptidase 90.059
Gzmagranzyme A0.058
Il18rapinterleukin 18 receptor accessory protein0.057
Il18r1interleukin 18 receptor 10.055
AF251705cDNA sequence AF2517050.053
Chi3l3chitinase 3-like 30.052
Ctswcathepsin W0.049
Fpr1formyl peptide receptor 10.048
Myo15myosin XV0.047
Fpr3formyl peptide receptor 30.047
Fbn1fibrillin 10.047
Plauplasminogen activator, urokinase0.046
Cx3cr1chemokine (C-X3-C) receptor 10.046
Col6a2collagen, type VI, alpha 20.044
Itgamintegrin alpha M0.044
Thbs2thrombospondin 20.044
Mitfmicrophthalmia-associated transcription factor0.044
Bdkrb1bradykinin receptor, beta 10.043
F2rl2coagulation factor II (thrombin) receptor-like 20.043
Ccl20chemokine (C-C motif) ligand 200.041
Xcr1chemokine (C motif) receptor 10.040
Dab2disabled homolog 2 (Drosophila)0.040
Il1rl1interleukin 1 receptor-like 10.039
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.038
Itgb2integrin beta 20.038
Itgalintegrin alpha L0.038
Clec4nC-type lectin domain family 4, member n0.038
Klra2killer cell lectin-like receptor, subfamily A, member 20.037
Icam1intercellular adhesion molecule 10.036
Ptgirprostaglandin I receptor (IP)0.036
Ccl12chemokine (C-C motif) ligand 120.036
Ush1cUsher syndrome 1C homolog (human)0.035
Ccr6chemokine (C-C motif) receptor 60.035
Cybbcytochrome b-245, beta polypeptide0.034
Wisp2WNT1 inducible signaling pathway protein 20.034
Col1a1collagen, type I, alpha 10.032
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.032
Ngpneutrophilic granule protein0.032
Cd7CD7 antigen0.032
Timp3tissue inhibitor of metalloproteinase 30.032
Htra3HtrA serine peptidase 30.032
Lilrb3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.031
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Timp1TIMP metallopeptidase inhibitor 10.448
Nkg7natural killer cell group 7 sequence0.287
Il2rbinterleukin 2 receptor, beta0.266
Cxcl10chemokine (C-X-C motif) ligand 100.254
Cd4Cd4 molecule0.238
Cd14CD14 molecule0.186
Slco2b1solute carrier organic anion transporter family, member 2b10.143
Hpgdshematopoietic prostaglandin D synthase0.140
S100a4S100 calcium-binding protein A40.116
Hmox1heme oxygenase (decycling) 10.095
Igsf6immunoglobulin superfamily, member 60.086
Anxa1annexin A10.080
Klrd1killer cell lectin-like receptor, subfamily D, member 10.078
P2rx7purinergic receptor P2X, ligand-gated ion channel, 70.074
Ctsbcathepsin B0.060
Ccr5chemokine (C-C motif) receptor 50.058
Ptger4prostaglandin E receptor 4 (subtype EP4)0.058
Tbxas1thromboxane A synthase 1, platelet0.056
Anxa2annexin A20.055
Itgamintegrin, alpha M0.055
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.053
Icam1intercellular adhesion molecule 10.052
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.052
Tlr7toll-like receptor 70.049
Stat6signal transducer and activator of transcription 60.049
Cd68Cd68 molecule0.048
Cd44Cd44 molecule0.048
S100a10S100 calcium binding protein A100.044
Arrdc1arrestin domain containing 10.041
Litaflipopolysaccharide-induced TNF factor0.040
Il1binterleukin 1 beta0.040
Gna11guanine nucleotide binding protein, alpha 110.039
PVRpoliovirus receptor0.038
Efnb1ephrin B10.037
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.037
G6pdglucose-6-phosphate dehydrogenase0.036
Pla1aphospholipase A1 member A0.034
Tcf4transcription factor 40.034
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.034
Clec4a3C-type lectin domain family 4, member a30.034
Fcn1ficolin (collagen/fibrinogen domain containing) 10.034
Lgals3lectin, galactoside-binding, soluble, 30.031
C1qccomplement component 1, q subcomponent, C chain0.030
Platplasminogen activator, tissue0.030
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.029
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.028
Capgcapping protein (actin filament), gelsolin-like0.028
Cd8aCD8a molecule0.027
Asgr2asialoglycoprotein receptor 20.027
Cd38CD38 molecule0.027
Sirpasignal-regulatory protein alpha0.027
Git1G protein-coupled receptor kinase interacting ArfGAP 10.026
Ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.026
Dab2disabled homolog 2 (Drosophila)0.026
Cd86CD86 molecule0.026
Dmbt1deleted in malignant brain tumors 10.025
Cmklr1chemokine-like receptor 10.025
Cybrd1cytochrome b reductase 10.025
Spp1secreted phosphoprotein 10.025
Cd53Cd53 molecule0.024
Calcrlcalcitonin receptor-like0.024
Itpr2inositol 1,4,5-triphosphate receptor, type 20.022
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.022
Gnb4guanine nucleotide binding protein (G protein), beta polypeptide 40.022
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.021
Gzmkgranzyme K0.021
Ly6cLy6-C antigen0.021
Ccr2chemokine (C-C motif) receptor 20.021
Prdm2PR domain containing 2, with ZNF domain0.021
Metrnlmeteorin, glial cell differentiation regulator-like0.021
Pacs1phosphofurin acidic cluster sorting protein 10.021
Ifitm3interferon induced transmembrane protein 30.020
Slit3slit homolog 3 (Drosophila)0.020
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.020
AhnakAHNAK nucleoprotein0.020
Pld4phospholipase D family, member 40.020
Ahraryl hydrocarbon receptor0.020
RT1-EC2RT1 class Ib, locus EC20.020
Gpnmbglycoprotein (transmembrane) nmb0.020
Eif2c2eukaryotic translation initiation factor 2C, 20.020
Cx3cl1chemokine (C-X3-C motif) ligand 10.019
Sult5a1sulfotransferase family 5A, member 10.019
Unc5bunc-5 homolog B (C. elegans)0.019
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.019
Sox17SRY (sex determining region Y)-box 170.019
Ptpreprotein tyrosine phosphatase, receptor type, E0.019
Xcl1chemokine (C motif) ligand 10.019
Clcn7chloride channel 70.018
Nos3nitric oxide synthase 3, endothelial cell0.018
TcrbT-cell receptor beta chain0.018
Fmnl1formin-like 10.017
Plaurplasminogen activator, urokinase receptor0.017
Cybbcytochrome b-245, beta polypeptide0.017
Lcklymphocyte-specific protein tyrosine kinase0.017
Timp3TIMP metallopeptidase inhibitor 30.017
Stk10serine/threonine kinase 100.017
RT1-A3RT1 class I, locus A30.017
Adcy4adenylate cyclase 40.017
Pde1bphosphodiesterase 1B, calmodulin-dependent0.016
P2ry12purinergic receptor P2Y, G-protein coupled, 120.016
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism