The network for 'positive regulation of cellular protein metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cellular protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.013
mpk-1Protein MPK-10.013
CELE_C01G6.5Protein C01G6.50.012
rps-2Protein RPS-20.011
pmk-1Protein PMK-10.011
K10D6.4Protein K10D6.40.011
cam-1Protein CAM-10.010
mig-38Protein MIG-380.010
pry-1Protein PRY-10.010
hsp-1Protein HSP-10.010
lin-36Protein LIN-360.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pcnaproliferating cell nuclear antigen0.448
bmp2bbone morphogenetic protein 2b0.228
tp53tumor protein p530.223
evx1even-skipped homeobox 10.195
fgfr1afibroblast growth factor receptor 1a0.187
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.158
ef1aelongation factor 1-alpha0.154
fzd7afrizzled homolog 7a0.154
nanos3nanos homolog 30.139
foxa2forkhead box A20.133
her6hairy-related 60.132
bocbrother of CDO0.121
smad9MAD homolog 9 (Drosophila)0.118
kdrlkinase insert domain receptor like0.118
tp53bp2tumor protein p53 binding protein, 20.115
shhasonic hedgehog a0.114
twist1atwist1a0.112
tbpl2TATA box binding protein like 20.107
pou5f1POU domain, class 5, transcription factor 10.106
acvr2aactivin receptor IIa0.101
mycamyelocytomatosis oncogene a0.094
baxabcl2-associated X protein, a0.083
sox9aSRY-box containing gene 9a0.082
fn1fibronectin 10.081
bmp2abone morphogenetic protein 2a0.077
cmybtranscription factor cmyb0.077
pkd2polycystic kidney disease 20.076
furinafurin (paired basic amino acid cleaving enzyme) a0.076
tgfb3transforming growth factor, beta 30.075
oepone-eyed pinhead0.074
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.074
sall4sal-like 4 (Drosophila)0.074
cnn2calponin 20.073
wnt1wingless-type MMTV integration site family, member 10.073
wnt10awingless-type MMTV integration site family, member 10a0.069
id3inhibitor of DNA binding 30.069
neo1neogenin 10.068
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.068
epas1bendothelial PAS domain protein 1b0.067
ptenaphosphatase and tensin homolog A0.065
neurog1neurogenin 10.065
dzip1DAZ interacting protein 10.065
mapk4mitogen-activated protein kinase 40.065
gata6GATA-binding protein 60.064
fesfeline sarcoma oncogene0.063
dharmadharma0.063
disp1dispatched homolog 1 (Drosophila)0.062
fstl1bfollistatin-like 1b0.062
igf1rainsulin-like growth factor 1a receptor0.059
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.057
mmp2matrix metalloproteinase 20.055
dnmt7DNA (cytosine-5-)-methyltransferase 70.054
fzd7bfrizzled homolog 7b0.054
dlx5adistal-less homeobox gene 5a0.053
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.052
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.052
ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.051
wu:fv91b12wu:fv91b120.049
tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.049
rarabretinoic acid receptor, alpha b0.049
p4ha2procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 20.048
npm1nucleophosmin 10.048
tnfsf10ltumor necrosis factor (ligand) superfamily, member 10 like0.048
ssrp1astructure specific recognition protein 1a0.048
inka1ainduced in neural crest by AP2, 1a0.047
hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.047
rargaretinoic acid receptor gamma a0.045
lyzlysozyme0.045
nkd1naked cuticle homolog 1 (Drosophila)0.044
wnt11rwingless-type MMTV integration site family, member 11, related0.044
sumo1SMT3 suppressor of mif two 3 homolog 1 (yeast)0.043
rspo3R-spondin 3 homolog (Xenopus laevis)0.043
tpm3tropomyosin 30.043
ube2naubiquitin-conjugating enzyme E2Na0.042
dag1dystroglycan 10.041
trpm7transient receptor potential cation channel, subfamily M, member 70.041
arf2ADP-ribosylation factor 20.041
ptrfbpolymerase I and transcript release factor b0.041
khdrbs1bKH domain containing, RNA binding, signal transduction associated 1b0.040
hmga1ahigh mobility group AT-hook 1a0.040
pak1p21/Cdc42/Rac1-activated kinase 10.040
inspreproinsulin0.040
ihhaIndian hedgehog homolog a0.039
cdh1cadherin 1, epithelial0.039
hbbe1.1hemoglobin beta embryonic-1.10.039
runx2brunt-related transcription factor 2b0.039
sulf1sulfatase 10.038
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.038
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.037
piwil1piwi-like 1 (Drosophila)0.037
jag2jagged 20.037
pax6bpaired box gene 6b0.037
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.037
igf1rbinsulin-like growth factor 1b receptor0.037
nrg1neuregulin 10.037
tfectranscription factor EC0.036
bnc2basonuclin 20.035
aox3aldehyde oxidase 30.035
si:ch211-212m21.5si:ch211-212m21.50.035
stc1lstanniocalcin 1, like0.035
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.996
rlrolled0.919
slmbsupernumerary limbs0.863
p53CG33336 gene product from transcript CG33336-RB0.861
CycECyclin E0.857
Fmr1CG6203 gene product from transcript CG6203-RC0.819
MadMothers against dpp0.794
mtsmicrotubule star0.757
twstwins0.746
lwrlesswright0.736
wtswarts0.736
drkdownstream of receptor kinase0.694
Rab11Rab-protein 110.632
shotshort stop0.629
E(spl)Enhancer of split0.616
Rho1CG8416 gene product from transcript CG8416-RB0.590
ykiyorkie0.583
dapdacapo0.580
dmdiminutive0.575
Rac1CG2248 gene product from transcript CG2248-RA0.571
Atg1Autophagy-specific gene 10.570
B52CG10851 gene product from transcript CG10851-RB0.561
Sin3ACG8815 gene product from transcript CG8815-RC0.556
Akt1CG4006 gene product from transcript CG4006-RA0.556
poloCG12306 gene product from transcript CG12306-RA0.542
bchsblue cheese0.533
Su(H)Suppressor of Hairless0.527
CycBCyclin B0.510
nejnejire0.505
bratbrain tumor0.501
PknProtein kinase related to protein kinase N0.494
RhebCG1081 gene product from transcript CG1081-RA0.491
Kap-alpha3karyopherin alpha30.464
tefutelomere fusion0.452
pucpuckered0.440
wgwingless0.439
S6kRPS6-p70-protein kinase0.438
LIMK1LIM-kinase10.422
rapretina aberrant in pattern0.415
PcPolycomb0.410
trbltribbles0.410
eyaeyes absent0.406
kaykayak0.394
Rac2CG8556 gene product from transcript CG8556-RA0.391
TomTwin of m40.389
stcksteamer duck0.384
bab2CG9102 gene product from transcript CG9102-RA0.377
SmoxSmad on X0.362
loqsloquacious0.351
Su(var)3-3Suppressor of variegation 3-30.349
kiskismet0.349
shnschnurri0.347
belbelle0.346
Dcp-1Death caspase-10.344
JraJun-related antigen0.342
pydpolychaetoid0.330
scbscab0.325
Dcr-1Dicer-10.321
dupdouble parked0.310
ththread0.308
DabDisabled0.306
DadDaughters against dpp0.304
lunaCG33473 gene product from transcript CG33473-RB0.295
kluklumpfuss0.292
trctricornered0.292
babobaboon0.285
FhosCG42610 gene product from transcript CG42610-RC0.283
SaraSmad anchor for receptor activation0.281
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.278
jubAjuba LIM protein0.277
CycACyclin A0.276
TER94CG2331 gene product from transcript CG2331-RA0.273
cicubitus interruptus0.265
phlpole hole0.259
ttvtout-velu0.258
chbchromosome bows0.257
Tsc1CG6147 gene product from transcript CG6147-RA0.251
CycGCyclin G0.250
effeffete0.246
aopanterior open0.245
Mekk1CG7717 gene product from transcript CG7717-RB0.245
Cdc42CG12530 gene product from transcript CG12530-RA0.243
katanin-60katanin 600.243
Pi3K92ECG4141 gene product from transcript CG4141-RB0.242
HLHmgammaE(spl) region transcript mgamma0.238
RelRelish0.234
Cul-5Cullin-50.229
eggeggless0.229
jarjaguar0.221
pzgputzig0.220
Stat92ESignal-transducer and activator of transcription protein at 92E0.218
rheaCG6831 gene product from transcript CG6831-RA0.214
jumujumeau0.212
RYBPRing and YY1 Binding Protein0.211
putpunt0.203
EgfrEpidermal growth factor receptor0.198
ctpcut up0.195
AGO2Argonaute 20.194
UbqnUbiquilin0.193
msnmisshapen0.193
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Jak2Janus kinase 20.619
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.433
Akt1v-akt murine thymoma viral oncogene homolog 10.406
Creb1cAMP responsive element binding protein 10.395
Sirpasignal-regulatory protein alpha0.392
Mpeg1macrophage expressed 10.368
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.345
Wdr26WD repeat domain 260.337
Prkcdprotein kinase C, delta0.334
Ptafrplatelet-activating factor receptor0.334
Agtr1aangiotensin II receptor, type 1a0.317
Cd4Cd4 molecule0.308
Metmet proto-oncogene0.300
Fgfr2fibroblast growth factor receptor 20.284
Il1r1interleukin 1 receptor, type I0.282
Ccr5chemokine (C-C motif) receptor 50.279
Crtapcartilage associated protein0.278
S100a8S100 calcium binding protein A80.266
S1pr2sphingosine-1-phosphate receptor 20.257
Nedd4neural precursor cell expressed, developmentally down-regulated 40.255
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.245
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.244
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.243
Cd38CD38 molecule0.240
HrasHarvey rat sarcoma virus oncogene0.233
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.228
Ptgfrnprostaglandin F2 receptor negative regulator0.217
Ciitaclass II, major histocompatibility complex, transactivator0.213
Gata4GATA binding protein 40.210
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.204
Mapk3mitogen activated protein kinase 30.200
Adarb2adenosine deaminase, RNA-specific, B20.195
Hoxa1homeo box A10.195
Mamdc4MAM domain containing 40.194
A3galt2alpha 1,3-galactosyltransferase 20.194
Bcanbrevican0.193
Smad1SMAD family member 10.192
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.192
Plauplasminogen activator, urokinase0.191
Nek9NIMA (never in mitosis gene a)- related kinase 90.191
Gna12guanine nucleotide binding protein (G protein) alpha 120.190
Rasa1RAS p21 protein activator (GTPase activating protein) 10.190
Jak1Janus kinase 10.189
Ccnd1cyclin D10.189
Ptprqprotein tyrosine phosphatase, receptor type, Q0.189
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.188
Calcrlcalcitonin receptor-like0.186
Myo1bmyosin Ib0.185
Arpc1bactin related protein 2/3 complex, subunit 1B0.182
Rab13RAB13, member RAS oncogene family0.181
RGD1564664similar to LOC387763 protein0.180
Itpr2inositol 1,4,5-triphosphate receptor, type 20.180
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.178
Olr1654olfactory receptor 16540.177
Casp2caspase 20.177
Mapk14mitogen activated protein kinase 140.174
Tpm3tropomyosin 3, gamma0.172
Adam17ADAM metallopeptidase domain 170.169
Rgs12regulator of G-protein signaling 120.169
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.168
Tgfatransforming growth factor alpha0.168
Tp53tumor protein p530.168
Fgf5fibroblast growth factor 50.166
Inhbainhibin beta-A0.166
Ednrbendothelin receptor type B0.165
Cdh5cadherin 50.163
Anxa4annexin A40.163
Ghrgrowth hormone receptor0.161
Rgs14regulator of G-protein signaling 140.161
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.161
Muskmuscle, skeletal, receptor tyrosine kinase0.160
Notch3Notch homolog 3 (Drosophila)0.160
Klf6Kruppel-like factor 60.160
Eif4heukaryotic translation initiation factor 4H0.160
Nrg1neuregulin 10.159
Il8rainterleukin 8 receptor, alpha0.158
Bcl2B-cell CLL/lymphoma 20.157
Oprm1opioid receptor, mu 10.157
Cd53Cd53 molecule0.157
Rbbp7retinoblastoma binding protein 70.157
Smad4SMAD family member 40.153
Inpp5dinositol polyphosphate-5-phosphatase D0.151
Anxa2annexin A20.150
Ncr1natural cytotoxicity triggering receptor 10.150
LOC100361261rCG23560-like0.150
Pld2phospholipase D20.149
Grb2growth factor receptor bound protein 20.148
Il18interleukin 180.147
Olr1500olfactory receptor 15000.147
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.147
Adora2aadenosine A2a receptor0.146
Gzmkgranzyme K0.146
Rac1ras-related C3 botulinum toxin substrate 10.145
Hpcahippocalcin0.144
Clcn5chloride channel 50.144
Arnt2aryl hydrocarbon receptor nuclear translocator 20.143
Myo1emyosin IE0.142
Myd88myeloid differentiation primary response gene 880.142
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.142
Adora3adenosine A3 receptor0.141
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PBS2Pbs2p0.940
HSL1Hsl1p0.698
RSP5Rsp5p0.628
BMH1Bmh1p0.463
MYO5Myo5p0.461
STE7Ste7p0.386
LSM1Lsm1p0.372
HOG1Hog1p0.371
SNF1Snf1p0.364
STE5Ste5p0.300
NBP2Nbp2p0.290
STE11Ste11p0.282
CDC12Cdc12p0.245
CDC55Cdc55p0.239
SSK2Ssk2p0.219
IMD3Imd3p0.216
CTR9Ctr9p0.205
CLA4Cla4p0.201
CKA2Cka2p0.198
CLB3Clb3p0.190
SDS22Sds22p0.173
CLB6Clb6p0.172
RPT6Rpt6p0.168
RTF1Rtf1p0.167
ECM29Ecm29p0.167
AHP1Ahp1p0.160
SSN3Ssn3p0.156
MSG5Msg5p0.156
SIP1Sip1p0.152
MGE1Mge1p0.150
PDE2Pde2p0.147
PBP4Pbp4p0.145
RAD23Rad23p0.144
CDC10Cdc10p0.141
MMS21Mms21p0.137
PAF1Paf1p0.134
BRO1Bro1p0.134
CMK1Cmk1p0.132
PSP2Psp2p0.129
PTP2Ptp2p0.128
SET2Set2p0.128
SSK1Ssk1p0.127
APC2Apc2p0.124
TPS1Tps1p0.122
RED1Red1p0.122
TIF1Tif1p0.122
SPT8Spt8p0.122
DST1Dst1p0.118
RAD16Rad16p0.117
SIC1Sic1p0.116
SGS1Sgs1p0.116
TIF4632Tif4632p0.114
ZIP1Zip1p0.113
ATG1Atg1p0.112
HYP2Hyp2p0.112
AEP1Aep1p0.111
FUS3Fus3p0.111
RHO1Rho1p0.110
TRA1Tra1p0.107
RPP2ARpp2ap0.106
SSK22Ssk22p0.105
GLN3Gln3p0.105
ARC1Arc1p0.104
DAP1Dap1p0.104
RPP1BRpp1bp0.104
ERO1Ero1p0.103
DNM1Dnm1p0.100
CIS1Cis1p0.100
RPG1Rpg1p0.099
RPP0Rpp0p0.099
RIM13Rim13p0.098
KSS1Kss1p0.097
CST9Cst9p0.095
MON2Mon2p0.094
SGV1Sgv1p0.093
PKH1Pkh1p0.092
SNF3Snf3p0.091
UBC13Ubc13p0.089
MEC1Mec1p0.088
RPB5Rpb5p0.088
CKS1Cks1p0.088
TEF1Tef1p0.087
DCC1Dcc1p0.087
PTP3Ptp3p0.087
MRM1Mrm1p0.085
HIR1Hir1p0.085
CBS1Cbs1p0.084
RNA15Rna15p0.084
RPL10Rpl10p0.083
SKI8Ski8p0.083
SEC12Sec12p0.083
PPH3Pph3p0.082
HAL5Hal5p0.082
PCH2Pch2p0.082
STE20Ste20p0.081
TOD6Tod6p0.081
MSH4Msh4p0.080
CLB5Clb5p0.080
CDC23Cdc23p0.080
PAN1Pan1p0.080