The network for 'positive regulation of protein polymerization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of protein polymerization

Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.

NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.999
IQGAP1IQ motif containing GTPase activating protein 10.994
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.989
BCAR1breast cancer anti-estrogen resistance 10.985
GAS7growth arrest-specific 70.981
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.974
FASLGFas ligand (TNF superfamily, member 6)0.972
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.967
ARPC3actin related protein 2/3 complex, subunit 3, 21kDa0.960
ABI1abl-interactor 10.947
WASLWiskott-Aldrich syndrome-like0.946
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.935
GRB2growth factor receptor-bound protein 20.934
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.923
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.910
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.872
FYNFYN oncogene related to SRC, FGR, YES0.831
DAAM1dishevelled associated activator of morphogenesis 10.824
PTK2PTK2 protein tyrosine kinase 20.809
PFN1profilin 10.797
TRIP10thyroid hormone receptor interactor 100.781
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.743
UNC119unc-119 homolog (C. elegans)0.741
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.732
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.706
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.690
VAV1vav 1 guanine nucleotide exchange factor0.669
MED15mediator complex subunit 150.635
FNBP1Lformin binding protein 1-like0.596
ARPC1Bactin related protein 2/3 complex, subunit 1B, 41kDa0.548
BAIAP2BAI1-associated protein 20.464
MAPRE1microtubule-associated protein, RP/EB family, member 10.418
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.403
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.400
CXCL2chemokine (C-X-C motif) ligand 20.397
TPM4tropomyosin 40.372
WASF1WAS protein family, member 10.357
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.356
NCKAP1NCK-associated protein 10.348
ARFIP2ADP-ribosylation factor interacting protein 20.340
DNM2dynamin 20.294
LRRK2leucine-rich repeat kinase 20.290
CTTNcortactin0.288
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.276
CCL5chemokine (C-C motif) ligand 50.276
NCF2neutrophil cytosolic factor 20.265
MTORmechanistic target of rapamycin (serine/threonine kinase)0.258
MAP3K11mitogen-activated protein kinase kinase kinase 110.251
FASFas (TNF receptor superfamily, member 6)0.243
FMR1fragile X mental retardation 10.241
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.237
ADAM19ADAM metallopeptidase domain 190.221
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.212
CXCL9chemokine (C-X-C motif) ligand 90.211
ADAM17ADAM metallopeptidase domain 170.198
RHOAras homolog gene family, member A0.198
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.188
TSC22D1TSC22 domain family, member 10.186
WDR1WD repeat domain 10.182
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.177
WBP11WW domain binding protein 110.170
CYFIP2cytoplasmic FMR1 interacting protein 20.162
ABI2abl-interactor 20.158
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.154
PFDN1prefoldin subunit 10.148
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.147
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.145
RASA1RAS p21 protein activator (GTPase activating protein) 10.145
PACSIN1protein kinase C and casein kinase substrate in neurons 10.143
TRIM39tripartite motif containing 390.140
NCKIPSDNCK interacting protein with SH3 domain0.139
NAV1neuron navigator 10.139
HTThuntingtin0.135
CCL4chemokine (C-C motif) ligand 40.133
FNBP1formin binding protein 10.127
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.124
PICALMphosphatidylinositol binding clathrin assembly protein0.124
RHOUras homolog gene family, member U0.123
CCR5chemokine (C-C motif) receptor 50.122
PRR5proline rich 5 (renal)0.121
ITSN1intersectin 1 (SH3 domain protein)0.121
HIPK2homeodomain interacting protein kinase 20.116
WASF2WAS protein family, member 20.114
PRKCAprotein kinase C, alpha0.113
FKBP1AFK506 binding protein 1A, 12kDa0.108
MEFVMediterranean fever0.100
CCL8chemokine (C-C motif) ligand 80.100
SORBS3sorbin and SH3 domain containing 30.100
RPTORregulatory associated protein of MTOR, complex 10.100
ZYXzyxin0.096
C4orf14chromosome 4 open reading frame 140.095
SOS1son of sevenless homolog 1 (Drosophila)0.093
PAK4p21 protein (Cdc42/Rac)-activated kinase 40.093
CYFIP1cytoplasmic FMR1 interacting protein 10.092
MAPKAP1mitogen-activated protein kinase associated protein 10.092
ARPC1Aactin related protein 2/3 complex, subunit 1A, 41kDa0.087
CCL2chemokine (C-C motif) ligand 20.086
TUBA4Atubulin, alpha 4a0.084
CORO1Ccoronin, actin binding protein, 1C0.083
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
vps-37Protein VPS-370.070
mig-2Protein MIG-20.055
praf-3Protein PRAF-30.019
smg-8Protein SMG-80.017
lin-24Protein LIN-240.014
arx-5Protein ARX-50.012
cdc-42Protein CDC-420.011
tag-232Protein TAG-2320.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fam49bafamily with sequence similarity 49, member Ba0.491
cotl1coactosin-like 1 (Dictyostelium)0.487
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.370
btkBruton agammaglobulinemia tyrosine kinase0.252
caspacaspase a0.231
ptpn6protein tyrosine phosphatase, non-receptor type 60.182
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.167
pfn1profilin 10.158
rab5cRAB5C, member RAS oncogene family0.157
zgc:64051zgc:640510.155
arhgdigRho GDP dissociation inhibitor (GDI) gamma0.151
ptprcprotein tyrosine phosphatase, receptor type, C0.144
gmfgglia maturation factor, gamma0.136
col6a6collagen, type VI, alpha 60.135
arpc4actin related protein 2/3 complex, subunit 40.134
lyzlysozyme0.133
zgc:92360zgc:923600.129
myl9lmyosin, light polypeptide 9, like0.117
nbl1neuroblastoma, suppression of tumorigenicity 10.116
cybacytochrome b-245, alpha polypeptide0.113
zgc:153867zgc:1538670.111
arpc5bactin related protein 2/3 complex, subunit 5B0.107
klf2bKruppel-like factor 2b0.105
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.105
colec11collectin sub-family member 110.104
s1pr2sphingosine-1-phosphate receptor 20.101
zgc:66317zgc:663170.099
arpc5aactin related protein 2/3 complex, subunit 5A0.092
pi4kbphosphatidylinositol 4-kinase, catalytic, beta0.089
myd88myeloid differentiation primary response gene (88)0.082
sept2septin 20.080
lasp1LIM and SH3 protein 10.078
twf1atwinfilin, actin-binding protein, homolog 1a0.070
c6orf115c6orf115 homolog (H. sapiens)0.070
zc4h2zinc finger, C4H2 domain containing0.068
plxnb2aplexin b2a0.067
fmo5flavin containing monooxygenase 50.066
slc25a25asolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a0.066
s100a10bS100 calcium binding protein A10b0.065
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.064
slc2a11lsolute carrier family 2 (facilitated glucose transporter), member 11-like0.062
iqgap1IQ motif containing GTPase activating protein 10.058
wdr1WD repeat domain 10.058
cyp2k16cytochrome P450, family 2, subfamily K, polypeptide160.057
hoxc11ahomeo box C11a0.056
gpt2lglutamic pyruvate transaminase (alanine aminotransferase) 2, like0.056
pnxposterior neuron-specific homeobox0.056
capza1acapping protein (actin filament) muscle Z-line, alpha 1a0.056
foxn1forkhead box N10.055
arf5ADP-ribosylation factor 50.055
sb:eu1555sb:eu15550.053
csf3rcolony stimulating factor 3 receptor (granulocyte)0.053
LOC100151049lysosomal-associated protein transmembrane 50.052
zgc:171553zgc:1715530.052
zgc:112355zgc:1123550.051
tp63tumor protein p630.051
cfl1cofilin 1 (non-muscle)0.051
tbeta-abeta thymosin-like protein 20.050
rc3rabconnectin 30.050
prkab1bprotein kinase, AMP-activated, beta 1 non-catalytic subunit, b0.050
hint2histidine triad nucleotide binding protein 20.050
lrrc33leucine rich repeat containing 330.049
zgc:85889zgc:858890.049
runx3runt-related transcription factor 30.048
wnt5awingless-type MMTV integration site family, member 5a0.048
abp1amiloride binding protein 1 (amine oxidase (copper-containing))0.047
nrg2aneuregulin 2a0.047
ncs1aneuronal calcium sensor 1a0.046
dlg2discs, large (Drosophila) homolog 20.046
zgc:114201zgc:1142010.046
mmp15amatrix metallopeptidase 15a0.045
sb:cb1091sb:cb10910.044
actr3ARP3 actin-related protein 3 homolog (yeast)0.044
id:ibd2217id:ibd22170.044
hmgn3high mobility group nucleosomal binding domain 30.043
sept7bseptin 7b0.043
npsnnephrosin0.042
zgc:152984zgc:1529840.042
tmem59ltransmembrane protein 59-like and transmembrane protein 59-like0.042
rac2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.042
nkx2.3NK2 transcription factor related 30.042
id:ibd2799id:ibd27990.042
scinlascinderin like a0.042
prph2aperipherin 2a (retinal degeneration, slow)0.042
plagl2pleiomorphic adenoma gene-like 20.042
wnt9awingless-type MMTV integration site family, member 9A0.042
LOC100006043Kruppel-like factor 5-like0.041
zgc:110409zgc:1104090.041
nadkaNAD kinase a0.041
snx1sorting nexin 10.041
far1fatty acyl CoA reductase 10.041
vegfabvascular endothelial growth factor Ab0.041
aldh3d1aldehyde dehydrogenase 3 family, member D10.040
ptger2aprostaglandin E receptor 2a (subtype EP2)0.040
klf4aKruppel-like transcription factor 4a0.040
nadl1.2neural adhesion molecule L1.20.040
eno2enolase 20.040
caspbcaspase b and caspase b-like0.040
lad1ladinin0.039
ulk2unc-51-like kinase 2 (C. elegans)0.039
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Arp66BActin-related protein 66B0.732
Vrp1Verprolin 10.448
katanin-60katanin 600.406
mbcmyoblast city0.364
twftwinfilin0.157
chicchickadee0.147
shotshort stop0.131
Arf51FADP ribosylation factor 51F0.108
Sra-1specifically Rac1-associated protein 10.090
bifbifocal0.084
Arc-p34CG10954 gene product from transcript CG10954-RA0.070
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.069
CkIIbetaCasein kinase II beta subunit0.068
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.065
ttktramtrack0.061
cpacapping protein alpha0.060
slssallimus0.059
S6kRPS6-p70-protein kinase0.059
didumdilute class unconventional myosin0.052
roboroundabout0.051
Cdc42CG12530 gene product from transcript CG12530-RA0.047
WASpCG1520 gene product from transcript CG1520-RA0.046
SosSon of sevenless0.046
cpbcapping protein beta0.041
twstwins0.040
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.039
Rho1CG8416 gene product from transcript CG8416-RB0.038
RalaRas-related protein0.034
wispwispy0.033
mtsmicrotubule star0.033
cindrCIN85 and CD2AP orthologue0.031
Ten-mTenascin major0.030
Pak3CG14895 gene product from transcript CG14895-RA0.028
CG12112CG12112 gene product from transcript CG12112-RA0.027
zipzipper0.025
CortactinCG3637 gene product from transcript CG3637-RA0.024
RhoGAP92BCG4755 gene product from transcript CG4755-RA0.024
Ras64BRas oncogene at 64B0.024
LaspCG3849 gene product from transcript CG3849-RB0.023
Arc-p20CG5972 gene product from transcript CG5972-RA0.023
HemHEM-protein0.023
par-6CG5884 gene product from transcript CG5884-RA0.021
Rab5Rab-protein 50.020
p16-ARCCG9881 gene product from transcript CG9881-RA0.020
Rac1CG2248 gene product from transcript CG2248-RA0.020
Pk61CProtein kinase 61C0.020
Dap160Dynamin associated protein 1600.020
Akt1CG4006 gene product from transcript CG4006-RA0.020
benbendless0.019
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.019
PakPAK-kinase0.019
Mob2CG11711 gene product from transcript CG11711-RC0.019
Mlc-cMyosin light chain cytoplasmic0.019
CG10641CG10641 gene product from transcript CG10641-RA0.018
MtlMig-2-like0.018
CG8578CG8578 gene product from transcript CG8578-RA0.018
staistathmin0.017
futschCG34387 gene product from transcript CG34387-RC0.017
mei-41meiotic 410.017
Eb1CG3265 gene product from transcript CG3265-RF0.017
kuzkuzbanian0.016
tmodtropomodulin0.016
MicalMolecule interacting with CasL0.016
kirrekin of irre0.016
CG31224CG31224 gene product from transcript CG31224-RA0.016
CG31048CG31048 gene product from transcript CG31048-RB0.016
shrbshrub0.016
CadNCadherin-N0.016
spospook0.015
foxoforkhead box, sub-group O0.015
fz2frizzled 20.015
beta-Specbeta Spectrin0.015
SybSynaptobrevin0.015
DAAMDishevelled Associated Activator of Morphogenesis0.014
Sema-1aCG18405 gene product from transcript CG18405-RD0.014
SdcSyndecan0.014
vihvihar0.013
snssticks and stones0.013
jarjaguar0.013
giggigas0.013
lunaCG33473 gene product from transcript CG33473-RB0.013
ShcSHC-adaptor protein0.013
trctricornered0.013
Cks30ACyclin-dependent kinase subunit 30A0.012
stgstring0.012
Vap-33-1CG5014 gene product from transcript CG5014-RB0.012
Dlc90FDynein light chain 90F0.012
htshu li tai shao0.012
p120ctnAdherens junction protein p1200.012
taytay bridge0.012
ndlnudel0.011
l(1)10Bblethal (1) 10Bb0.011
eglegalitarian0.011
CdsACDP diglyceride synthetase0.011
Act88FActin 88F0.011
vavCG7893 gene product from transcript CG7893-RB0.011
rheaCG6831 gene product from transcript CG6831-RA0.011
CG32528CG32528 gene product from transcript CG32528-RA0.011
cnocanoe0.011
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.011
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.201
Pfn1profilin 10.165
Mapre1microtubule-associated protein, RP/EB family, member 10.123
LOC100362824caveolin 2-like0.096
NsfN-ethylmaleimide-sensitive factor0.074
Arpc5actin related protein 2/3 complex, subunit 50.068
Tpm4tropomyosin 40.058
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.056
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.046
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.045
Efhd2EF-hand domain family, member D20.045
Map2k1mitogen activated protein kinase kinase 10.043
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.035
Dnm1ldynamin 1-like0.035
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.034
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.031
Srisorcin0.030
Rnf4ring finger protein 40.029
Rab7aRAB7A, member RAS oncogene family0.028
Arpc2actin related protein 2/3 complex, subunit 20.027
Syt4synaptotagmin IV0.025
Tpm3tropomyosin 3, gamma0.025
Atp6v1b2ATPase, H transporting, lysosomal V1 subunit B20.020
Camk2gcalcium/calmodulin-dependent protein kinase II gamma0.018
Wdr1WD repeat domain 10.018
Map1amicrotubule-associated protein 1A0.017
Clic1chloride intracellular channel 10.016
Eif4heukaryotic translation initiation factor 4H0.016
Scamp2secretory carrier membrane protein 20.014
Jak1Janus kinase 10.014
Arf1ADP-ribosylation factor 10.013
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.013
Cugbp2CUG triplet repeat, RNA binding protein 20.013
Irf1interferon regulatory factor 10.012
Gria2glutamate receptor, ionotropic, AMPA 20.012
Tubb5tubulin, beta 50.012
Cav1caveolin 1, caveolae protein0.012
S100a10S100 calcium binding protein A100.012
Arf6ADP-ribosylation factor 60.012
Bcat1branched chain aminotransferase 1, cytosolic0.012
Il17rainterleukin 17 receptor A0.011
Rhoaras homolog gene family, member A0.011
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.011
Vamp1vesicle-associated membrane protein 10.011
Mapk1mitogen activated protein kinase 10.011
Emp1epithelial membrane protein 10.010
Lcp1lymphocyte cytosolic protein 10.010
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ASK1Ask1p0.998
DAD4Dad4p0.987
SPC34Spc34p0.987
DAD2Dad2p0.983
DAD1Dad1p0.982
SPC19Spc19p0.960
DUO1Duo1p0.943
DAM1Dam1p0.699
LSB1Lsb1p0.672
ARP2Arp2p0.664
ARC19Arc19p0.564
MYO5Myo5p0.555
HSK3Hsk3p0.512
ARC40Arc40p0.481
ARC35Arc35p0.350
TCO89Tco89p0.281
ARP3Arp3p0.247
ARC15Arc15p0.197
DAD3Dad3p0.150
ABP1Abp1p0.106
RVS167Rvs167p0.090
SLA2Sla2p0.077
AVO1Avo1p0.061
CAP2Cap2p0.051
SSK2Ssk2p0.046
KOG1Kog1p0.032
LAS17Las17p0.032
AIP1Aip1p0.029
YPL108Whypothetical protein0.028
SAC6Sac6p0.028
ARP10Arp10p0.027
RHO1Rho1p0.026
SRV2Srv2p0.023
SRD1Srd1p0.023
LEU2Leu2p0.022
AIM7Aim7p0.021
GYL1Gyl1p0.021
CRN1Crn1p0.020
YLR162Whypothetical protein0.020
MER1Mer1p0.020
YOL038C-Ahypothetical protein0.019
CHA1Cha1p0.019
YIR035Chypothetical protein0.019
YLR264C-Ahypothetical protein0.019
YPL014Whypothetical protein0.018
YBR016Whypothetical protein0.018
BBC1Bbc1p0.017
URA3Ura3p0.017
SPL2Spl2p0.017
ACT1Act1p0.017
PAN1Pan1p0.016
VRP1Vrp1p0.016
YLR042Chypothetical protein0.016
PRS2Prs2p0.016
ARG8Arg8p0.016
EHT1Eht1p0.016
REE1Ree1p0.016
BUL1Bul1p0.016
BTN2Btn2p0.015
CRP1Crp1p0.015
YBR013Chypothetical protein0.015
YAR068Whypothetical protein0.015
ZPS1Zps1p0.015
AUA1Aua1p0.015
STU2Stu2p0.015
SRO77Sro77p0.015
HXT3Hxt3p0.015
PEP1Pep1p0.014
CUP1-1Cup1-1p0.014
KAR9Kar9p0.014
INP52Inp52p0.014
ATP6Atp6p0.014
CPD1Cpd1p0.014
TRI1Tri1p0.014
YJL107Chypothetical protein0.014
TSC11Tsc11p0.014
YPK1Ypk1p0.014
SFT1Sft1p0.014
SWM2Swm2p0.014
PCL9Pcl9p0.013
YOL013W-Ahypothetical protein0.013
SWC7Swc7p0.013
YLR108Chypothetical protein0.013
ADH2Adh2p0.013
YPR157Whypothetical protein0.013
DUR1,2Dur1,2p0.013
FMT1Fmt1p0.013
RHO5Rho5p0.013
UPS3Ups3p0.013
PPH21Pph21p0.013
OPT2Opt2p0.013
MF(ALPHA)2Mf(alpha)2p0.013
PTR2Ptr2p0.012
SCP1Scp1p0.012
ICS2Ics2p0.012
BIT61Bit61p0.012
YIL151Chypothetical protein0.012
IZH4Izh4p0.012
HPF1Hpf1p0.012
YPR096Chypothetical protein0.012