The network for 'sensory organ development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

sensory organ development

The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
CREBBPCREB binding protein0.965
RB1retinoblastoma 10.963
HDAC1histone deacetylase 10.912
EP300E1A binding protein p3000.830
CDK2cyclin-dependent kinase 20.768
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.754
RBBP4retinoblastoma binding protein 40.750
EGFRepidermal growth factor receptor0.745
JUNjun proto-oncogene0.695
SMAD2SMAD family member 20.694
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.610
COL1A1collagen, type I, alpha 10.605
CAV1caveolin 1, caveolae protein, 22kDa0.598
TP53tumor protein p530.520
SIN3ASIN3 homolog A, transcription regulator (yeast)0.510
CSNK1Ecasein kinase 1, epsilon0.475
FUSfused in sarcoma0.454
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.435
TAL1T-cell acute lymphocytic leukemia 10.423
APCadenomatous polyposis coli0.422
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.412
NR4A1nuclear receptor subfamily 4, group A, member 10.410
MCM7minichromosome maintenance complex component 70.388
FOSFBJ murine osteosarcoma viral oncogene homolog0.386
NOTCH1notch 10.367
SMAD4SMAD family member 40.366
YAP1Yes-associated protein 10.365
NCOR1nuclear receptor corepressor 10.320
PPARAperoxisome proliferator-activated receptor alpha0.312
PBX1pre-B-cell leukemia homeobox 10.310
NCOR2nuclear receptor corepressor 20.306
JUNBjun B proto-oncogene0.275
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.266
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.260
PRMT1protein arginine methyltransferase 10.257
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.253
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.251
NOTCH3notch 30.246
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.240
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.240
ESR1estrogen receptor 10.239
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.222
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.216
SP1Sp1 transcription factor0.206
HIC1hypermethylated in cancer 10.206
PTPN11protein tyrosine phosphatase, non-receptor type 110.199
SMAD3SMAD family member 30.196
ATF2activating transcription factor 20.193
CHAF1Achromatin assembly factor 1, subunit A (p150)0.190
FGFR1fibroblast growth factor receptor 10.185
JAG1jagged 10.179
APPamyloid beta (A4) precursor protein0.175
RUNX1runt-related transcription factor 10.174
DNM2dynamin 20.174
COL4A1collagen, type IV, alpha 10.173
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.172
POU3F2POU class 3 homeobox 20.170
BBS10Bardet-Biedl syndrome 100.168
MYOD1myogenic differentiation 10.164
DUSP1dual specificity phosphatase 10.161
HIPK2homeodomain interacting protein kinase 20.161
ENGendoglin0.159
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.157
GATA4GATA binding protein 40.142
TP53BP2tumor protein p53 binding protein, 20.139
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.138
SFPQsplicing factor proline/glutamine-rich0.137
ERBB2IPerbb2 interacting protein0.136
SOX1SRY (sex determining region Y)-box 10.135
NFYAnuclear transcription factor Y, alpha0.135
FSTL1follistatin-like 10.134
CHD3chromodomain helicase DNA binding protein 30.133
ADAM15ADAM metallopeptidase domain 150.132
DAXXdeath-domain associated protein0.131
MDM2Mdm2 p53 binding protein homolog (mouse)0.130
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.129
COL4A2collagen, type IV, alpha 20.128
SMAD1SMAD family member 10.127
COL2A1collagen, type II, alpha 10.126
SOX11SRY (sex determining region Y)-box 110.125
PMLpromyelocytic leukemia0.123
UHRF2ubiquitin-like with PHD and ring finger domains 20.123
SOX2SRY (sex determining region Y)-box 20.123
NRP1neuropilin 10.122
DVL3dishevelled, dsh homolog 3 (Drosophila)0.121
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.120
PTPN1protein tyrosine phosphatase, non-receptor type 10.117
SCHIP1schwannomin interacting protein 10.117
CASP3caspase 3, apoptosis-related cysteine peptidase0.116
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.115
CCT8chaperonin containing TCP1, subunit 8 (theta)0.115
COL1A2collagen, type I, alpha 20.111
ANAPC4anaphase promoting complex subunit 40.110
SIX6SIX homeobox 60.109
ZMYM2zinc finger, MYM-type 20.109
ANAPC5anaphase promoting complex subunit 50.109
LBX1ladybird homeobox 10.108
CRYBA2crystallin, beta A20.106
ATP6V0D1ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d10.106
INADLInaD-like (Drosophila)0.105
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
vab-3Protein VAB-30.027
egl-44Protein EGL-440.023
unc-73Protein UNC-730.022
pxf-1Protein PXF-10.020
bar-1Protein BAR-10.018
atn-1Protein ATN-10.017
pha-4Protein PHA-40.015
col-2Protein COL-20.014
hlh-1Protein HLH-10.014
sma-6Protein SMA-60.011
egl-46Protein EGL-460.011
irx-1Protein IRX-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
eya1eyes absent homolog 11.000
fgf3fibroblast growth factor 31.000
cdh2cadherin 2, neuronal1.000
irx3airoquois homeobox protein 3a0.999
sox9aSRY-box containing gene 9a0.998
atoh1aatonal homolog 1a0.998
rx1retinal homeobox gene 10.997
lmx1b.1LIM homeobox transcription factor 1, beta 10.996
sox2SRY-box containing gene 20.995
kif17kinesin family member 170.995
gdf6agrowth differentiation factor 6a0.995
sox10SRY-box containing gene 100.995
notch3notch homolog 30.994
bdnfbrain-derived neurotrophic factor0.993
fgfr1afibroblast growth factor receptor 1a0.993
pax2apaired box gene 2a0.993
tfap2atranscription factor AP-2 alpha0.993
aldh1a3aldehyde dehydrogenase 1 family, member A30.992
myo7aamyosin VIIAa0.992
twist3twist30.990
crabp2acellular retinoic acid binding protein 2, a0.990
aldh1a2aldehyde dehydrogenase 1 family, member A20.989
dlx3bdistal-less homeobox gene 3b0.987
gbx2gastrulation brain homeo box 20.987
six4bsine oculis homeobox homolog 4b0.985
col2a1acollagen type II, alpha-1a0.985
osr2odd-skipped related 2 (Drosophila)0.984
kitakit receptor a0.984
tbx1T-box 10.984
pcsk5aproprotein convertase subtilisin/kexin type 5a0.984
bmp2bbone morphogenetic protein 2b0.981
shhbsonic hedgehog b0.981
rx3retinal homeobox gene 30.981
lmo4aLIM domain only 4a0.980
stmstarmaker0.980
sox3SRY-box containing gene 30.980
pitx3paired-like homeodomain transcription factor 30.978
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.977
bmp4bone morphogenetic protein 40.977
dkk1bdickkopf 1b0.976
notch1anotch homolog 1a0.973
pax6bpaired box gene 6b0.971
ptf1apancreas specific transcription factor, 1a0.969
otx1aorthodenticle homolog 1a0.969
fgfr4fibroblast growth factor receptor 40.968
clrn1clarin 10.967
gpr126G protein-coupled receptor 1260.967
sox1aSRY-box containing gene 1a0.967
gli2aGLI-Kruppel family member GLI2a0.967
foxi1forkhead box I10.966
jag2jagged 20.965
hoxb1bhomeo box B1b0.964
cx30.3connexin 30.30.964
rorbRAR-related orphan receptor B0.963
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.963
fzd8afrizzled homolog 8a0.961
ndr2nodal-related 20.959
foxg1aforkhead box G1a0.956
fgf8afibroblast growth factor 8 a0.955
eve1even-skipped-like10.954
cdh6cadherin 60.953
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.952
tmietransmembrane inner ear0.948
dlx2adistal-less homeobox gene 2a0.947
axin2axin 2 (conductin, axil)0.945
flhfloating head0.945
dctn1adynactin 1a0.945
lamb1alaminin, beta 1a0.945
pou3f3bPOU class 3 homeobox 3b0.944
fgf10afibroblast growth factor 10a0.944
fn1fibronectin 10.943
igf1rbinsulin-like growth factor 1b receptor0.943
shhasonic hedgehog a0.940
hmx3homeo box (H6 family) 30.938
tbx2bT-box 2b0.938
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.933
zgc:112329zgc:1123290.933
epb41l5erythrocyte membrane protein band 4.1 like 50.929
tyrtyrosinase0.928
lama5laminin, alpha 50.928
traf4atnf receptor-associated factor 4a0.927
runx1runt-related transcription factor 10.927
bhlhe22basic helix-loop-helix family, member e220.924
ctbp2lC-terminal binding protein 2, like0.923
atp6v1e1bATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b0.923
hhiphedgehog interacting protein0.922
ndr1nodal-related 10.921
kdrlkinase insert domain receptor like0.921
tll1tolloid-like 10.918
rx2retinal homeobox gene 20.917
pvrl1apoliovirus receptor-related 1a0.914
crb2acrumbs homolog 2a0.913
dlx4bdistal-less homeobox gene 4b0.912
lama1laminin, alpha 10.910
dladeltaA0.907
scn1bbsodium channel, voltage-gated, type I, beta b0.906
ush1cUsher syndrome 1C (autosomal recessive, severe)0.906
gata3GATA-binding protein 30.905
gli2bGLI-Kruppel family member GLI2b0.903
wnt11wingless-type MMTV integration site family, member 110.903
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.429
Esr2estrogen receptor 2 (ER beta)0.365
Pou3f2POU class 3 homeobox 20.352
Actbactin, beta0.336
Tgfbr2transforming growth factor, beta receptor II0.289
RT1-EC2RT1 class Ib, locus EC20.269
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.255
Gja5gap junction protein, alpha 50.253
Casp3caspase 30.233
Sdc3syndecan 30.233
Mipmajor intrinsic protein of lens fiber0.220
Cryaacrystallin, alpha A0.214
Apoeapolipoprotein E0.208
Foxd3forkhead box D30.206
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.191
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.188
FosFBJ osteosarcoma oncogene0.184
Aebp1AE binding protein 10.177
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.172
Barhl2BarH-like homeobox 20.172
Cntn2contactin 2 (axonal)0.171
Lamc1laminin, gamma 10.170
St18suppression of tumorigenicity 180.163
Accn3amiloride-sensitive cation channel 30.161
Csf3colony stimulating factor 3 (granulocyte)0.160
Vax1ventral anterior homeobox 10.160
Mapre1microtubule-associated protein, RP/EB family, member 10.160
Crygccrystallin, gamma C0.157
Slc13a2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.151
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.145
Nr4a1nuclear receptor subfamily 4, group A, member 10.141
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.134
Fgf17fibroblast growth factor 170.129
Rararetinoic acid receptor, alpha0.128
Agtr1bangiotensin II receptor, type 1b0.123
Gria4glutamate receptor, ionotrophic, AMPA 40.122
Ctsql2cathepsin Q-like 20.120
Oprd1opioid receptor, delta 10.120
Lin7blin-7 homolog b (C. elegans)0.117
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.116
Egr2early growth response 20.116
Trim29tripartite motif-containing 290.112
Id3inhibitor of DNA binding 30.106
Krtap1-5keratin associated protein 1-50.106
Dusp4dual specificity phosphatase 40.106
Fgfr2fibroblast growth factor receptor 20.106
Tcfe2atranscription factor E2a0.105
Shox2short stature homeobox 20.105
Mapk3mitogen activated protein kinase 30.105
Ednraendothelin receptor type A0.105
Tbxa2rthromboxane A2 receptor0.103
Aldh3a1aldehyde dehydrogenase 3 family, member A10.102
Timm44translocase of inner mitochondrial membrane 44 homolog (yeast)0.102
Grifingalectin-related inter-fiber protein0.102
Atxn1ataxin 10.101
Colec12collectin sub-family member 120.100
Trhr2thyrotropin releasing hormone receptor 20.099
Opn1swopsin 1 (cone pigments), short-wave-sensitive0.098
Dusp1dual specificity phosphatase 10.096
Msx2msh homeobox 20.096
Col8a1collagen, type VIII, alpha 10.095
A4galtalpha 1,4-galactosyltransferase0.094
Adrb1adrenergic, beta-1-, receptor0.092
Lyve1lymphatic vessel endothelial hyaluronan receptor 10.092
Adam17ADAM metallopeptidase domain 170.091
Sbk1SH3-binding domain kinase 10.090
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.090
Chgbchromogranin B0.089
Sod3superoxide dismutase 3, extracellular0.089
Chrm1cholinergic receptor, muscarinic 10.089
Nr2f2nuclear receptor subfamily 2, group F, member 20.089
Eef2eukaryotic translation elongation factor 20.089
Junbjun B proto-oncogene0.089
Efna1ephrin A10.088
Cldn19claudin 190.087
RT1-CE12RT1 class I, locus CE120.086
Rhoaras homolog gene family, member A0.086
Tmsb4xthymosin beta 4, X-linked0.085
Ece1endothelin converting enzyme 10.083
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.083
Hoxd3homeo box D30.083
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.083
Ascl1achaete-scute complex homolog 1 (Drosophila)0.082
Pfn1profilin 10.082
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.082
Rgs19regulator of G-protein signaling 190.081
Timp2TIMP metallopeptidase inhibitor 20.080
Prl3b1Prolactin family 3, subfamily b, member 10.080
Atp7bATPase, Cu++ transporting, beta polypeptide0.080
Ltbrlymphotoxin beta receptor (TNFR superfamily, member 3)0.080
KlKlotho0.078
Fam70bfamily with sequence similarity 70, member B0.078
Ctsccathepsin C0.078
Nr4a2nuclear receptor subfamily 4, group A, member 20.077
Mettl7bmethyltransferase like 7B0.076
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.076
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.075
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.075
Nrxn3neurexin 30.074
Foxd1forkhead box D10.074
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism