The network for 'negative regulation of voltage gated calcium channel activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of voltage gated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.

NameDescriptionProbabilityFunc Analog Organism
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 21.000
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit1.000
ADORA2Aadenosine A2a receptor0.996
CRHcorticotropin releasing hormone0.981
CALM1calmodulin 1 (phosphorylase kinase, delta)0.978
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.968
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.952
CAPNS1calpain, small subunit 10.685
ACTN4actinin, alpha 40.683
CAPZBcapping protein (actin filament) muscle Z-line, beta0.311
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.265
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.261
GFAPglial fibrillary acidic protein0.240
RGS6regulator of G-protein signaling 60.213
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.181
GNG5guanine nucleotide binding protein (G protein), gamma 50.172
NECAB2N-terminal EF-hand calcium binding protein 20.163
SPRED1sprouty-related, EVH1 domain containing 10.150
CALCAcalcitonin-related polypeptide alpha0.146
SLC6A7solute carrier family 6 (neurotransmitter transporter, L-proline), member 70.121
EMX1empty spiracles homeobox 10.117
CAPN2calpain 2, (m/II) large subunit0.116
AP2M1adaptor-related protein complex 2, mu 1 subunit0.108
RAMP2receptor (G protein-coupled) activity modifying protein 20.105
GNG2guanine nucleotide binding protein (G protein), gamma 20.097
GNG4guanine nucleotide binding protein (G protein), gamma 40.090
GNG7guanine nucleotide binding protein (G protein), gamma 70.089
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.086
NRBP1nuclear receptor binding protein 10.085
GABBR2gamma-aminobutyric acid (GABA) B receptor, 20.084
ACTL6Bactin-like 6B0.084
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 10.083
CLTBclathrin, light chain B0.081
KCNH1potassium voltage-gated channel, subfamily H (eag-related), member 10.078
CHRNA4cholinergic receptor, nicotinic, alpha 40.077
RAMP3receptor (G protein-coupled) activity modifying protein 30.076
CXCR5chemokine (C-X-C motif) receptor 50.071
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.068
PTGER1prostaglandin E receptor 1 (subtype EP1), 42kDa0.066
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.064
DRD2dopamine receptor D20.063
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.061
SLC5A5solute carrier family 5 (sodium iodide symporter), member 50.060
RIPK3receptor-interacting serine-threonine kinase 30.059
RHBDL1rhomboid, veinlet-like 1 (Drosophila)0.055
CCKBRcholecystokinin B receptor0.054
MAP3K3mitogen-activated protein kinase kinase kinase 30.053
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.051
HTR1A5-hydroxytryptamine (serotonin) receptor 1A0.051
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif, 70.049
HCRThypocretin (orexin) neuropeptide precursor0.047
ADRA1Dadrenergic, alpha-1D-, receptor0.046
GHSRgrowth hormone secretagogue receptor0.046
RHOrhodopsin0.045
CRYBB3crystallin, beta B30.045
CLCNKBchloride channel Kb0.045
ACHEacetylcholinesterase0.044
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.043
GUCA2Bguanylate cyclase activator 2B (uroguanylin)0.043
ATP1B2ATPase, Na+/K+ transporting, beta 2 polypeptide0.043
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.042
PAX8paired box 80.041
ARPC1Aactin related protein 2/3 complex, subunit 1A, 41kDa0.041
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.041
LBX1ladybird homeobox 10.040
PICK1protein interacting with PRKCA 10.039
GJD2gap junction protein, delta 2, 36kDa0.038
OPRD1opioid receptor, delta 10.038
ACTR1AARP1 actin-related protein 1 homolog A, centractin alpha (yeast)0.038
KRT83keratin 830.038
TSC22D1TSC22 domain family, member 10.038
FBN3fibrillin 30.038
ARF5ADP-ribosylation factor 50.037
MYL3myosin, light chain 3, alkali; ventricular, skeletal, slow0.036
CELF3CUGBP, Elav-like family member 30.035
SPTBspectrin, beta, erythrocytic0.035
CRHR1corticotropin releasing hormone receptor 10.035
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.035
GH2growth hormone 20.034
MASP2mannan-binding lectin serine peptidase 20.034
P2RX2purinergic receptor P2X, ligand-gated ion channel, 20.033
BCANbrevican0.033
NPPCnatriuretic peptide C0.032
KCNJ3potassium inwardly-rectifying channel, subfamily J, member 30.032
SLC2A4solute carrier family 2 (facilitated glucose transporter), member 40.032
EVX1even-skipped homeobox 10.032
ESRRBestrogen-related receptor beta0.031
HOXD8homeobox D80.031
TBXA2Rthromboxane A2 receptor0.030
EXTL1exostoses (multiple)-like 10.030
HCRTR1hypocretin (orexin) receptor 10.030
TACR1tachykinin receptor 10.029
PRKCGprotein kinase C, gamma0.029
CCND2cyclin D20.029
LHBluteinizing hormone beta polypeptide0.029
TEFthyrotrophic embryonic factor0.029
FOXD3forkhead box D30.029
HRH3histamine receptor H30.028
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.028
CNGB1cyclic nucleotide gated channel beta 10.028
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism