The network for 'regulation of histone acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of histone acetylation

Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.

NameDescriptionProbabilityFunc Analog Organism
WDR5WD repeat domain 50.941
MAPK14mitogen-activated protein kinase 140.511
MAPK3mitogen-activated protein kinase 30.446
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.267
ZNF496zinc finger protein 4960.255
HCFC1host cell factor C1 (VP16-accessory protein)0.243
MAPK1mitogen-activated protein kinase 10.224
CHD8chromodomain helicase DNA binding protein 80.204
ARRB2arrestin, beta 20.203
MBIPMAP3K12 binding inhibitory protein 10.200
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.173
BCL9B-cell CLL/lymphoma 90.163
SIN3ASIN3 homolog A, transcription regulator (yeast)0.157
SETD8SET domain containing (lysine methyltransferase) 80.155
TGIF1TGFB-induced factor homeobox 10.150
COASYCoA synthase0.144
ARRB1arrestin, beta 10.140
HIPK2homeodomain interacting protein kinase 20.137
ENGendoglin0.136
TAL1T-cell acute lymphocytic leukemia 10.131
VAC14Vac14 homolog (S. cerevisiae)0.129
RBBP5retinoblastoma binding protein 50.122
NRIP1nuclear receptor interacting protein 10.106
SUZ12suppressor of zeste 12 homolog (Drosophila)0.090
EP300E1A binding protein p3000.086
CDAN1congenital dyserythropoietic anemia, type I0.081
RUNX1runt-related transcription factor 10.080
RUVBL1RuvB-like 1 (E. coli)0.080
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.077
PAFAH1B3platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)0.076
MAP2K4mitogen-activated protein kinase kinase 40.076
DUSP1dual specificity phosphatase 10.076
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.075
CFL1cofilin 1 (non-muscle)0.072
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.072
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.072
MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)0.071
RB1retinoblastoma 10.068
YY1YY1 transcription factor0.065
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.059
SMC1Astructural maintenance of chromosomes 1A0.059
DUSP3dual specificity phosphatase 30.058
NCOA6nuclear receptor coactivator 60.055
CHEK2CHK2 checkpoint homolog (S. pombe)0.052
WWOXWW domain containing oxidoreductase0.051
CSNK2A1casein kinase 2, alpha 1 polypeptide0.051
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.050
EEDembryonic ectoderm development0.048
CTBP1C-terminal binding protein 10.047
BRCA1breast cancer 1, early onset0.047
EEF2Keukaryotic elongation factor-2 kinase0.046
GSK3Bglycogen synthase kinase 3 beta0.045
INO80INO80 homolog (S. cerevisiae)0.044
PMLpromyelocytic leukemia0.042
SRFserum response factor (c-fos serum response element-binding transcription factor)0.037
MRFAP1L1Morf4 family associated protein 1-like 10.037
CCDC101coiled-coil domain containing 1010.036
ATMataxia telangiectasia mutated0.035
BARD1BRCA1 associated RING domain 10.035
USP22ubiquitin specific peptidase 220.032
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.031
BAZ2Bbromodomain adjacent to zinc finger domain, 2B0.030
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.030
MATR3matrin 30.030
GNAQguanine nucleotide binding protein (G protein), q polypeptide0.029
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.029
MEN1multiple endocrine neoplasia I0.029
MAP2K1mitogen-activated protein kinase kinase 10.029
TLK1tousled-like kinase 10.028
HDAC1histone deacetylase 10.027
STAG1stromal antigen 10.027
SETD7SET domain containing (lysine methyltransferase) 70.026
KAT5K(lysine) acetyltransferase 50.026
USP5ubiquitin specific peptidase 5 (isopeptidase T)0.026
PEA15phosphoprotein enriched in astrocytes 150.025
IKZF3IKAROS family zinc finger 3 (Aiolos)0.025
TRRAPtransformation/transcription domain-associated protein0.024
PTPRJprotein tyrosine phosphatase, receptor type, J0.024
ESR1estrogen receptor 10.024
ATG7ATG7 autophagy related 7 homolog (S. cerevisiae)0.024
TBPTATA box binding protein0.023
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.023
PRKCAprotein kinase C, alpha0.023
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.023
MBPmyelin basic protein0.022
CREB1cAMP responsive element binding protein 10.022
SOX13SRY (sex determining region Y)-box 130.022
SKIv-ski sarcoma viral oncogene homolog (avian)0.022
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)0.022
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.022
TP53BP1tumor protein p53 binding protein 10.022
MYST1MYST histone acetyltransferase 10.021
ATXN7ataxin 70.021
PARP1poly (ADP-ribose) polymerase 10.021
FZD5frizzled homolog 5 (Drosophila)0.020
EIF3Ceukaryotic translation initiation factor 3, subunit C0.020
GDI1GDP dissociation inhibitor 10.020
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.020
GPBP1GC-rich promoter binding protein 10.020
C19orf46chromosome 19 open reading frame 460.020
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
dikdiskette0.401
kniknirps0.247
GmdGDP-mannose 4,6-dehydratase0.164
Sir2CG5216 gene product from transcript CG5216-RA0.152
CG9772CG9772 gene product from transcript CG9772-RB0.114
msl-3male-specific lethal 30.101
HcfHost cell factor0.079
SmoxSmad on X0.067
ushu-shaped0.065
Su(var)3-7Suppressor of variegation 3-70.052
Atg6Autophagy-specific gene 60.051
CG3363CG3363 gene product from transcript CG3363-RB0.048
simjsimjang0.047
D12CG13400 gene product from transcript CG13400-RA0.042
KrKruppel0.035
pashapartner of drosha0.035
DrefDNA replication-related element factor0.031
Gap1GTPase-activating protein 10.031
SuURSuppressor of Under-Replication0.026
btlbreathless0.022
krzkurtz0.021
bynbrachyenteron0.020
Gyc76CGuanylyl cyclase at 76C0.019
Jarid2CG3654 gene product from transcript CG3654-RD0.019
Tao-1CG14217 gene product from transcript CG14217-RF0.018
snasnail0.017
CG10990CG10990 gene product from transcript CG10990-RB0.016
msl-1male-specific lethal 10.015
slp1sloppy paired 10.014
l(3)05822lethal (3) 058220.014
Atg18Autophagy-specific gene 180.014
tldtolloid0.013
KrnKeren0.013
Chrac-14CG13399 gene product from transcript CG13399-RA0.012
CG6241CG6241 gene product from transcript CG6241-RA0.012
sinusinuous0.012
ScmSex comb on midleg0.012
fu2CG9233 gene product from transcript CG9233-RA0.011
pzgputzig0.011
emsempty spiracles0.010
nufnuclear fallout0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.864
Neurod1neurogenic differentiation 10.851
Ptenphosphatase and tensin homolog0.810
Tgfb1transforming growth factor, beta 10.670
Smad4MAD homolog 4 (Drosophila)0.663
Lepleptin0.593
Col1a1collagen, type I, alpha 10.572
Nos3nitric oxide synthase 3, endothelial cell0.441
Esr1estrogen receptor 1 (alpha)0.419
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.414
Il10interleukin 100.407
Otx2orthodenticle homolog 2 (Drosophila)0.389
Nos2nitric oxide synthase 2, inducible0.367
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.319
Shhsonic hedgehog0.298
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.283
Ascl1achaete-scute complex homolog 1 (Drosophila)0.266
Tal1T-cell acute lymphocytic leukemia 10.247
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.241
Runx1runt related transcription factor 10.229
Kiss1KiSS-1 metastasis-suppressor0.229
Leprleptin receptor0.222
Neurog2neurogenin 20.210
Gata1GATA binding protein 10.186
Cav1caveolin 1, caveolae protein0.163
Csf1colony stimulating factor 1 (macrophage)0.162
Ptpn11protein tyrosine phosphatase, non-receptor type 110.150
Emx1empty spiracles homolog 1 (Drosophila)0.144
Gata4GATA binding protein 40.143
Atg12autophagy-related 12 (yeast)0.142
Snai1snail homolog 1 (Drosophila)0.135
Vdrvitamin D receptor0.126
Ppargperoxisome proliferator activated receptor gamma0.121
Ptf1apancreas specific transcription factor, 1a0.117
Hand1heart and neural crest derivatives expressed transcript 10.113
Arrb2arrestin, beta 20.112
Pax6paired box gene 60.109
Gli2GLI-Kruppel family member GLI20.105
Nr5a1nuclear receptor subfamily 5, group A, member 10.101
Mab21l2mab-21-like 2 (C. elegans)0.100
Hrhairless0.097
Socs1suppressor of cytokine signaling 10.091
Zeb1zinc finger E-box binding homeobox 10.091
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.090
Brca2breast cancer 20.089
Smc3structural maintenace of chromosomes 30.085
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.084
Hdac2histone deacetylase 20.082
Msx1homeobox, msh-like 10.079
En1engrailed 10.078
Onecut1one cut domain, family member 10.077
Arandrogen receptor0.074
Neurod4neurogenic differentiation 40.073
Inhbainhibin beta-A0.072
Nhlh1nescient helix loop helix 10.072
Ikzf1IKAROS family zinc finger 10.069
Zfpm2zinc finger protein, multitype 20.068
Kitkit oncogene0.066
Fesfeline sarcoma oncogene0.065
Pax3paired box gene 30.065
MecomMDS1 and EVI1 complex locus0.064
Hba-xhemoglobin X, alpha-like embryonic chain in Hba complex0.064
Hdac1histone deacetylase 10.063
Hoxa1homeobox A10.063
Brca1breast cancer 10.063
Vegfavascular endothelial growth factor A0.063
Kitlkit ligand0.062
Hoxa10homeobox A100.061
Nos1nitric oxide synthase 1, neuronal0.061
Lhx9LIM homeobox protein 90.061
Tnftumor necrosis factor0.059
Foxn1forkhead box N10.059
Hand2heart and neural crest derivatives expressed transcript 20.058
Stat3signal transducer and activator of transcription 30.058
Rxraretinoid X receptor alpha0.056
Vaspvasodilator-stimulated phosphoprotein0.053
Esr2estrogen receptor 2 (beta)0.052
Tlx3T-cell leukemia, homeobox 30.051
Wfikkn2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.050
Slc4a1solute carrier family 4 (anion exchanger), member 10.049
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.049
Igf1insulin-like growth factor 10.048
Twist2twist homolog 2 (Drosophila)0.047
Rb1retinoblastoma 10.046
Lhx3LIM homeobox protein 30.046
Lmx1bLIM homeobox transcription factor 1 beta0.045
Gnrh1gonadotropin releasing hormone 10.045
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.044
Ciccapicua homolog (Drosophila)0.044
Fshrfollicle stimulating hormone receptor0.044
Foxd3forkhead box D30.044
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.043
Lhx5LIM homeobox protein 50.043
Apcadenomatosis polyposis coli0.043
Ep300E1A binding protein p3000.042
Prlrprolactin receptor0.042
Gata6GATA binding protein 60.042
Mmp9matrix metallopeptidase 90.041
Dsg4desmoglein 40.041
Neurog3neurogenin 30.041
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Stxbp3syntaxin binding protein 30.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
TRA1Tra1p0.357
HHT1Hht1p0.177
NGG1Ngg1p0.145
TAF6Taf6p0.125
MOT1Mot1p0.096
SET2Set2p0.094
BDF1Bdf1p0.069
SPT8Spt8p0.059
TAF12Taf12p0.044
NOP10Nop10p0.035
TAF8Taf8p0.034
SGF29Sgf29p0.033
ESF1Esf1p0.032
TEC1Tec1p0.032
TAF11Taf11p0.031
RCO1Rco1p0.031
UBP8Ubp8p0.031
SPT16Spt16p0.029
INO80Ino80p0.027
HIR1Hir1p0.026
FUS3Fus3p0.025
CTR9Ctr9p0.023
SRD1Srd1p0.022
HFI1Hfi1p0.020
YLR264C-Ahypothetical protein0.019
LEU2Leu2p0.019
TAF3Taf3p0.018
YLR162Whypothetical protein0.018
MSG5Msg5p0.018
TAF5Taf5p0.018
CUP1-1Cup1-1p0.017
ARG8Arg8p0.017
NUP157Nup157p0.017
DIG1Dig1p0.017
HXT3Hxt3p0.017
CCT8Cct8p0.017
CHD1Chd1p0.016
YLR042Chypothetical protein0.016
MRC1Mrc1p0.016
MER1Mer1p0.015
SWI1Swi1p0.015
YOL038C-Ahypothetical protein0.015
URA3Ura3p0.015
HIR2Hir2p0.015
SPL2Spl2p0.015
MF(ALPHA)2Mf(alpha)2p0.015
YIR035Chypothetical protein0.014
UME1Ume1p0.014
ARP10Arp10p0.014
YAR068Whypothetical protein0.014
YPR157Whypothetical protein0.014
YIL151Chypothetical protein0.014
ATP6Atp6p0.013
SKI2Ski2p0.013
RLF2Rlf2p0.013
MF(ALPHA)1Mf(alpha)1p0.013
CRP1Crp1p0.013
ARP4Arp4p0.013
ADA2Ada2p0.013
SPT20Spt20p0.013
RGD2Rgd2p0.012
OPT2Opt2p0.012
HOHop0.012
BSC1Bsc1p0.012
AUA1Aua1p0.012
PTP3Ptp3p0.012
SPT5Spt5p0.012
YBR013Chypothetical protein0.011
IZH4Izh4p0.011
HPF1Hpf1p0.011
UME6Ume6p0.011
FMT1Fmt1p0.011
SWC3Swc3p0.011
SDC1Sdc1p0.011
TYE7Tye7p0.011
YLR040Chypothetical protein0.011
SCM4Scm4p0.011
ZPS1Zps1p0.011
REV1Rev1p0.011
YOL013W-Ahypothetical protein0.011
YGR017Whypothetical protein0.011
KSS1Kss1p0.011
MDN1Mdn1p0.010
YJL181Whypothetical protein0.010
HST3Hst3p0.010
IOC2Ioc2p0.010
GBP2Gbp2p0.010
STE2Ste2p0.010
SPT7Spt7p0.010