The network for 'ovarian follicle development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ovarian follicle development

The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.

Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.776
NRP1neuropilin 10.533
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.431
BCL2L1BCL2-like 10.356
EIF2B4eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa0.244
TIMP2TIMP metallopeptidase inhibitor 20.221
POU5F1POU class 5 homeobox 10.159
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.155
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.140
TEKTEK tyrosine kinase, endothelial0.120
PCGF2polycomb group ring finger 20.097
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.063
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.052
BCL2B-cell CLL/lymphoma 20.048
FGFR2fibroblast growth factor receptor 20.041
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.038
HDAC6histone deacetylase 60.035
BAK1BCL2-antagonist/killer 10.031
SHC2SHC (Src homology 2 domain containing) transforming protein 20.030
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.026
RNR2l-rRNA0.026
PPP5Cprotein phosphatase 5, catalytic subunit0.022
FOXO1forkhead box O10.020
HTThuntingtin0.019
TBPTATA box binding protein0.017
BADBCL2-associated agonist of cell death0.017
PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.016
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.016
MYLK2myosin light chain kinase 20.015
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.014
RNF144Bring finger protein 144B0.013
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.013
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.013
GDF5growth differentiation factor 50.012
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.011
KITLGKIT ligand0.011
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.011
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.011
BCL2L11BCL2-like 11 (apoptosis facilitator)0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cyp19a1acytochrome P450, family 19, subfamily A, polypeptide 1a0.728
bdnfbrain-derived neurotrophic factor0.321
paqr7bprogestin and adipoQ receptor family member VII, b0.303
bmp2bbone morphogenetic protein 2b0.298
gdf9growth differentiation factor 90.276
bmp15bone morphogenetic protein 150.222
rag1recombination activating gene 10.202
igf3insulin-like growth factor 30.192
paqr8progestin and adipoQ receptor family member VIII0.178
cldn2claudin 20.172
ptgs1prostaglandin-endoperoxide synthase 10.154
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.152
fshrfollicle stimulating hormone receptor0.138
sox7SRY-box containing gene 70.137
esr1estrogen receptor 10.134
gnrh2gonadotropin-releasing hormone 20.123
cpla2cytosolic phospholipase a20.109
gscgoosecoid0.109
hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.106
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.094
runx1runt-related transcription factor 10.089
hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.081
csf1racolony stimulating factor 1 receptor, a0.080
ptgs2aprostaglandin-endoperoxide synthase 2a0.080
cldndclaudin d0.077
fabp11afatty acid binding protein 11a0.077
cyp17a1cytochrome P450, family 17, subfamily A, polypeptide 10.072
pitx2paired-like homeodomain transcription factor 20.070
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.067
kiss1rbKISS1 receptor b0.065
tbx2bT-box 2b0.064
rbm24aRNA binding motif protein 24a0.064
igf1insulin-like growth factor 10.063
pou1f1POU domain, class 1, transcription factor 10.060
mmp9matrix metalloproteinase 90.059
inhbaainhibin, beta Aa0.058
acvr2aactivin receptor IIa0.058
osr1odd-skipped related 1 (Drosophila)0.057
hsd17b3hydroxysteroid (17-beta) dehydrogenase 30.056
ptprbprotein tyrosine phosphatase, receptor type, b0.055
prdm1aPR domain containing 1a, with ZNF domain0.052
dact2dapper homolog 2, antagonist of beta-catenin (xenopus)0.050
ptgeslprostaglandin E synthase 2-like0.048
vegfaavascular endothelial growth factor Aa0.048
brca2breast cancer 2, early onset0.048
starsteroidogenic acute regulatory protein0.047
hbbe1.1hemoglobin beta embryonic-1.10.047
prox1prospero-related homeobox gene 10.047
spry4sprouty (Drosophila) homolog 40.047
cdh23cadherin-like 230.047
bbc3BCL2 binding component 30.046
spns2spinster homolog 2 (Drosophila)0.045
frzbfrizzled-related protein0.045
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.045
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.043
cdh5cadherin 50.043
vasavasa homolog0.042
fabp10afatty acid binding protein 10a, liver basic0.042
aplnrbapelin receptor b0.042
plcg1phospholipase C, gamma 10.041
cbr1lcarbonyl reductase 1-like0.040
cdkn1acyclin-dependent kinase inhibitor 1A0.039
bmperBMP binding endothelial regulator0.039
baxabcl2-associated X protein, a0.038
sod2superoxide dismutase 2, mitochondrial0.037
lhbluteinizing hormone, beta polypeptide0.037
rspo1R-spondin homolog (Xenopus laevis)0.037
aldh1a2aldehyde dehydrogenase 1 family, member A20.036
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.036
klf4Kruppel-like factor 40.036
nanos3nanos homolog 30.035
ddx41DEAD (Asp-Glu-Ala-Asp) box polypeptide 410.035
fanciFanconi anemia, complementation group I0.035
tagln2transgelin 20.035
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.035
per2period homolog 2 (Drosophila)0.034
syce2synaptonemal complex central element protein 20.034
amotl2aangiomotin like 2a0.033
epas1bendothelial PAS domain protein 1b0.033
fanclFanconi anemia, complementation group L0.033
smyd3SET and MYND domain containing 30.033
evx1even-skipped homeobox 10.032
mt2metallothionein 20.032
foxo3bforkhead box O3b0.032
podxlpodocalyxin-like0.031
zgc:111821zgc:1118210.031
arid4aAT rich interactive domain 4A (RBP1-like)0.031
ldb2bLIM-domain binding factor 2b0.030
appaamyloid beta (A4) precursor protein a0.030
esr2bestrogen receptor 2b0.030
kiss1KiSS-1 metastasis-suppressor0.030
bcl2l1bcl2-like 10.029
tbx20T-box 200.029
tnfaip1tumor necrosis factor, alpha-induced protein 1 (endothelial)0.029
pomcaproopiomelanocortin a0.029
si:dkey-22a1.3si:dkey-22a1.30.029
alcamaactivated leukocyte cell adhesion molecule a0.028
cry1acryptochrome 1a0.028
fzd7afrizzled homolog 7a0.028
cyp2p6cytochrome P450, family 2, subfamily P, polypeptide 60.027
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ptenphosphatase and tensin homolog1.000
Amhr2anti-Mullerian hormone type 2 receptor0.999
Nos3nitric oxide synthase 3, endothelial cell0.999
Fshrfollicle stimulating hormone receptor0.999
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.998
Kiss1KiSS-1 metastasis-suppressor0.996
Pax8paired box gene 80.995
Trp53transformation related protein 530.995
Tgfbr2transforming growth factor, beta receptor II0.994
Nr5a1nuclear receptor subfamily 5, group A, member 10.983
Fgfr2fibroblast growth factor receptor 20.979
Bcl2B-cell leukemia/lymphoma 20.962
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.961
Csf1colony stimulating factor 1 (macrophage)0.958
Esr1estrogen receptor 1 (alpha)0.951
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.938
Ptpn11protein tyrosine phosphatase, non-receptor type 110.918
Arandrogen receptor0.915
Inhbainhibin beta-A0.913
Nr0b1nuclear receptor subfamily 0, group B, member 10.895
Tgfb2transforming growth factor, beta 20.842
Ghrgrowth hormone receptor0.819
Kitkit oncogene0.811
Cdk2cyclin-dependent kinase 20.806
Nognoggin0.788
Lhcgrluteinizing hormone/choriogonadotropin receptor0.784
Pax2paired box gene 20.762
Ctnnb1catenin (cadherin associated protein), beta 10.755
Egfrepidermal growth factor receptor0.746
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.706
Esr2estrogen receptor 2 (beta)0.660
Vegfavascular endothelial growth factor A0.656
Bmp4bone morphogenetic protein 40.650
Fbn1fibrillin 10.635
Fstfollistatin0.621
Loxlysyl oxidase0.620
Flt4FMS-like tyrosine kinase 40.595
BaxBCL2-associated X protein0.580
Nkx2-1NK2 homeobox 10.561
Apcadenomatosis polyposis coli0.554
Hoxa1homeobox A10.549
Tgfbr3transforming growth factor, beta receptor III0.544
Duox2dual oxidase 20.539
Foxc1forkhead box C10.536
Notch2Notch gene homolog 2 (Drosophila)0.535
Fgfr1fibroblast growth factor receptor 10.522
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.502
Kiss1rKISS1 receptor0.492
Amhanti-Mullerian hormone0.489
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.473
Kdrkinase insert domain protein receptor0.469
Lhx3LIM homeobox protein 30.455
Ldlrlow density lipoprotein receptor0.449
Fgfr3fibroblast growth factor receptor 30.449
Leprleptin receptor0.448
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.434
Notch1Notch gene homolog 1 (Drosophila)0.426
CblCasitas B-lineage lymphoma0.400
Mmp9matrix metallopeptidase 90.369
Tgfb1transforming growth factor, beta 10.351
Klklotho0.330
Engendoglin0.314
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.303
Gnrhrgonadotropin releasing hormone receptor0.302
Mmp2matrix metallopeptidase 20.293
Foxc2forkhead box C20.289
Jag1jagged 10.280
Dhhdesert hedgehog0.272
Gnrh1gonadotropin releasing hormone 10.266
Cdh5cadherin 50.258
Psen1presenilin 10.254
Sall4sal-like 4 (Drosophila)0.252
Fgf8fibroblast growth factor 80.247
Pgrprogesterone receptor0.245
Hoxd9homeobox D90.239
Col1a1collagen, type I, alpha 10.237
Cgaglycoprotein hormones, alpha subunit0.231
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.228
Adam17a disintegrin and metallopeptidase domain 170.226
Cdk6cyclin-dependent kinase 60.222
Bmpr1abone morphogenetic protein receptor, type 1A0.221
Acvrl1activin A receptor, type II-like 10.215
Rxraretinoid X receptor alpha0.213
Tcl1T-cell lymphoma breakpoint 10.212
Acvr1activin A receptor, type 10.211
Efnb2ephrin B20.209
Meox2mesenchyme homeobox 20.202
Shhsonic hedgehog0.201
Klf5Kruppel-like factor 50.191
Hif1ahypoxia inducible factor 1, alpha subunit0.187
Tgfbr1transforming growth factor, beta receptor I0.177
Inhbbinhibin beta-B0.172
Runx2runt related transcription factor 20.170
Smad3MAD homolog 3 (Drosophila)0.169
Lepleptin0.167
Gata6GATA binding protein 60.166
Prlrprolactin receptor0.164
Stat3signal transducer and activator of transcription 30.155
Tbx1T-box 10.153
Kitlkit ligand0.151
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ednraendothelin receptor type A0.030
Pipprolactin induced protein0.028
Prrx1paired related homeobox 10.026
Castcalpastatin0.023
Fgf10fibroblast growth factor 100.021
Homer3homer homolog 3 (Drosophila)0.021
Arnt2aryl hydrocarbon receptor nuclear translocator 20.020
Igfbp5insulin-like growth factor binding protein 50.020
Smad7SMAD family member 70.019
Foxd3forkhead box D30.019
Tgfbr3transforming growth factor, beta receptor III0.017
F13a1coagulation factor XIII, A1 polypeptide0.017
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.017
LOC100360587hypothetical protein LOC1003605870.017
Ucnurocortin0.016
Lamc1laminin, gamma 10.016
Pik3r3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.016
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.016
Padi1peptidyl arginine deiminase, type I0.016
RGD1564327similar to integrin alpha 80.016
Git1G protein-coupled receptor kinase interacting ArfGAP 10.016
Galr2galanin receptor 20.015
Foxs1forkhead box S10.015
Adamts13ADAM metallopeptidase with thrombospondin type 1 motif, 130.015
Serpina5serine (or cysteine) peptidase inhibitor, clade A, member 50.015
Efnb1ephrin B10.015
Ptger2prostaglandin E receptor 2 (subtype EP2)0.015
Mtus1mitochondrial tumor suppressor 10.014
Defb1defensin beta 10.014
Leprleptin receptor0.014
Slc22a2solute carrier family 22 (organic cation transporter), member 20.014
Tgfbr2transforming growth factor, beta receptor II0.014
Cpxm2carboxypeptidase X (M14 family), member 20.014
Ccr1chemokine (C-C motif) receptor 10.014
Gucy2fguanylate cyclase 2F0.013
Cyb5r1cytochrome b5 reductase 10.013
Starsteroidogenic acute regulatory protein0.013
Tymsthymidylate synthetase0.013
Shc3SHC (Src homology 2 domain containing) transforming protein 30.013
Gja5gap junction protein, alpha 50.013
Chadchondroadherin0.013
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.013
Cercamcerebral endothelial cell adhesion molecule0.013
Emp1epithelial membrane protein 10.013
Arntaryl hydrocarbon receptor nuclear translocator0.012
Vcanversican0.012
Tpothyroid peroxidase0.012
Maneamannosidase, endo-alpha0.012
Wnt5awingless-type MMTV integration site family, member 5A0.012
Ctrcchymotrypsin C (caldecrin)0.012
Nedd4neural precursor cell expressed, developmentally down-regulated 40.012
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.012
Crygccrystallin, gamma C0.012
Mybphmyosin binding protein H0.012
KitlgKIT ligand0.012
Chrnb4cholinergic receptor, nicotinic, beta 40.012
Kcna6potassium voltage gated channel, shaker related subfamily, member 60.012
Ccl28chemokine (C-C motif) ligand 280.012
Tcof1Treacher Collins-Franceschetti syndrome 1 homolog (human)0.012
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.012
Gja4gap junction protein, alpha 40.012
RY2G5potential ligand-binding protein0.012
Pdynprodynorphin0.012
Tpc1808tropic 18080.012
Olfml2bolfactomedin-like 2B0.011
Il12binterleukin 12B0.011
Pdpnpodoplanin0.011
Angptl4angiopoietin-like 40.011
Sirpasignal-regulatory protein alpha0.011
Plinperilipin0.011
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.011
Celcarboxyl ester lipase0.011
A3galt2alpha 1,3-galactosyltransferase 20.011
Lin7clin-7 homolog C (C. elegans)0.011
Adcy5adenylate cyclase 50.011
Cdc25acell division cycle 25 homolog A (S. pombe)0.011
Ucn2urocortin 20.011
Ednrbendothelin receptor type B0.011
Ptgfrprostaglandin F receptor0.011
Fbln5fibulin 50.011
Il1rapinterleukin 1 receptor accessory protein0.011
Bst1bone marrow stromal cell antigen 10.011
Sulf1sulfatase 10.011
LOC286980putative pheromone receptor (Go-VN13B)0.011
Ddr2discoidin domain receptor tyrosine kinase 20.011
Lmnalamin A0.010
Trhrthyrotropin releasing hormone receptor0.010
Foxd4forkhead box D40.010
Pthparathyroid hormone0.010
Nos2nitric oxide synthase 2, inducible0.010
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.010
Rfc1replication factor C (activator 1) 10.010
Adrb1adrenergic, beta-1-, receptor0.010
Gria4glutamate receptor, ionotrophic, AMPA 40.010
Ldhclactate dehydrogenase C0.010
Ampd1adenosine monophosphate deaminase 1 (isoform M)0.010
Acaa2acetyl-Coenzyme A acyltransferase 20.010
Csf3colony stimulating factor 3 (granulocyte)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism