The network for 'embryonic placenta development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic placenta development

The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.

NameDescriptionProbabilityFunc Analog Organism
SP1Sp1 transcription factor1.000
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.996
EP300E1A binding protein p3000.996
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.952
EPAS1endothelial PAS domain protein 10.951
NCOA3nuclear receptor coactivator 30.947
CREBBPCREB binding protein0.937
SMAD3SMAD family member 30.934
ESR1estrogen receptor 10.902
STK4serine/threonine kinase 40.842
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.838
EGR1early growth response 10.820
NCOR1nuclear receptor corepressor 10.798
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.777
NCOA2nuclear receptor coactivator 20.776
KRT6Bkeratin 6B0.766
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.687
SKILSKI-like oncogene0.631
NR4A1nuclear receptor subfamily 4, group A, member 10.631
POU5F1POU class 5 homeobox 10.612
RARAretinoic acid receptor, alpha0.601
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.570
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.544
KAT2BK(lysine) acetyltransferase 2B0.541
MAPK14mitogen-activated protein kinase 140.531
RUNX1runt-related transcription factor 10.486
FBXL12F-box and leucine-rich repeat protein 120.485
FGF1fibroblast growth factor 1 (acidic)0.483
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.473
PKD2polycystic kidney disease 2 (autosomal dominant)0.455
NCOA1nuclear receptor coactivator 10.429
TAL1T-cell acute lymphocytic leukemia 10.426
MLL3myeloid/lymphoid or mixed-lineage leukemia 30.425
ST14suppression of tumorigenicity 14 (colon carcinoma)0.412
GADD45Bgrowth arrest and DNA-damage-inducible, beta0.406
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.402
RXRAretinoid X receptor, alpha0.390
CREB1cAMP responsive element binding protein 10.373
STK3serine/threonine kinase 30.358
HSPB1heat shock 27kDa protein 10.356
PKD1polycystic kidney disease 1 (autosomal dominant)0.325
SAV1salvador homolog 1 (Drosophila)0.305
FGF10fibroblast growth factor 100.301
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.298
PTPN11protein tyrosine phosphatase, non-receptor type 110.297
MAPK1mitogen-activated protein kinase 10.289
SMAD2SMAD family member 20.281
HIPK2homeodomain interacting protein kinase 20.278
BHLHE40basic helix-loop-helix family, member e400.278
DUSP1dual specificity phosphatase 10.270
SMAD4SMAD family member 40.268
FAM46Afamily with sequence similarity 46, member A0.265
TP53tumor protein p530.262
NCOR2nuclear receptor corepressor 20.254
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.254
AHRaryl hydrocarbon receptor0.249
BAG1BCL2-associated athanogene0.247
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.245
MTA1metastasis associated 10.242
NOTCH1notch 10.241
BAG3BCL2-associated athanogene 30.232
YY1YY1 transcription factor0.228
MED13mediator complex subunit 130.225
PUM2pumilio homolog 2 (Drosophila)0.225
MAXMYC associated factor X0.218
TCF4transcription factor 40.211
NIPBLNipped-B homolog (Drosophila)0.211
AKT1v-akt murine thymoma viral oncogene homolog 10.209
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.204
PIAS1protein inhibitor of activated STAT, 10.204
KRT18keratin 180.200
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.198
JUNjun proto-oncogene0.193
EGLN3egl nine homolog 3 (C. elegans)0.193
ARNTaryl hydrocarbon receptor nuclear translocator0.190
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.190
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.187
HSPA8heat shock 70kDa protein 80.187
STAT5Asignal transducer and activator of transcription 5A0.186
CTGFconnective tissue growth factor0.183
EGLN1egl nine homolog 1 (C. elegans)0.181
FOSFBJ murine osteosarcoma viral oncogene homolog0.181
VEZF1vascular endothelial zinc finger 10.177
JUBjub, ajuba homolog (Xenopus laevis)0.174
CENPJcentromere protein J0.164
SPENspen homolog, transcriptional regulator (Drosophila)0.157
PEBP4phosphatidylethanolamine-binding protein 40.157
TCF12transcription factor 120.157
EFTUD2elongation factor Tu GTP binding domain containing 20.155
FGF7fibroblast growth factor 70.153
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.151
MTA3metastasis associated 1 family, member 30.148
IER2immediate early response 20.144
MAP1Smicrotubule-associated protein 1S0.139
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.137
TRRAPtransformation/transcription domain-associated protein0.135
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.134
MED25mediator complex subunit 250.134
CEBPDCCAAT/enhancer binding protein (C/EBP), delta0.132
TRIM33tripartite motif containing 330.130
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Ptpn11protein tyrosine phosphatase, non-receptor type 111.000
Shhsonic hedgehog0.999
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.999
Fgf8fibroblast growth factor 80.998
Foxc1forkhead box C10.998
Pitx2paired-like homeodomain transcription factor 20.997
Hand2heart and neural crest derivatives expressed transcript 20.996
Ctnnb1catenin (cadherin associated protein), beta 10.994
Itgb1integrin beta 1 (fibronectin receptor beta)0.993
Hand1heart and neural crest derivatives expressed transcript 10.992
Hif1ahypoxia inducible factor 1, alpha subunit0.991
Gata4GATA binding protein 40.989
Fgf10fibroblast growth factor 100.985
Notch2Notch gene homolog 2 (Drosophila)0.980
Egfrepidermal growth factor receptor0.980
Gata6GATA binding protein 60.978
Rxraretinoid X receptor alpha0.978
Gli3GLI-Kruppel family member GLI30.976
Foxc2forkhead box C20.967
Jag1jagged 10.965
Foxa2forkhead box A20.963
Vegfavascular endothelial growth factor A0.960
Ptenphosphatase and tensin homolog0.957
Cdx2caudal type homeobox 20.954
Efnb2ephrin B20.946
Otx2orthodenticle homolog 2 (Drosophila)0.942
Pax2paired box gene 20.939
Leprleptin receptor0.928
Smad6MAD homolog 6 (Drosophila)0.922
Foxg1forkhead box G10.921
Stat3signal transducer and activator of transcription 30.918
Rargretinoic acid receptor, gamma0.911
Tbx3T-box 30.897
Hoxd13homeobox D130.896
Pitx1paired-like homeodomain transcription factor 10.892
Bmp4bone morphogenetic protein 40.875
Tcfap2ctranscription factor AP-2, gamma0.875
Ptgs2prostaglandin-endoperoxide synthase 20.875
Neurog1neurogenin 10.871
Wt1Wilms tumor 1 homolog0.870
Dlx5distal-less homeobox 50.866
Tbx1T-box 10.861
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.857
Krt17keratin 170.854
Tcfap2atranscription factor AP-2, alpha0.850
Hoxa1homeobox A10.849
Sox9SRY-box containing gene 90.846
Nr3c1nuclear receptor subfamily 3, group C, member 10.843
Adra2badrenergic receptor, alpha 2b0.839
Tlx3T-cell leukemia, homeobox 30.834
Nos3nitric oxide synthase 3, endothelial cell0.825
FosFBJ osteosarcoma oncogene0.824
MecomMDS1 and EVI1 complex locus0.818
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.802
Vhlvon Hippel-Lindau tumor suppressor0.801
Neurog2neurogenin 20.796
Tbx5T-box 50.792
Pcdh12protocadherin 120.783
Notch1Notch gene homolog 1 (Drosophila)0.781
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.779
Tal1T-cell acute lymphocytic leukemia 10.779
Alx4aristaless-like homeobox 40.777
Padi3peptidyl arginine deiminase, type III0.774
Pax3paired box gene 30.772
Trp63transformation related protein 630.765
Hes5hairy and enhancer of split 5 (Drosophila)0.762
Wnt7awingless-related MMTV integration site 7A0.761
Vangl2vang-like 2 (van gogh, Drosophila)0.754
Sox2SRY-box containing gene 20.754
Hoxd11homeobox D110.750
Lhx3LIM homeobox protein 30.745
Pax8paired box gene 80.731
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.725
Dkk1dickkopf homolog 1 (Xenopus laevis)0.724
Chd7chromodomain helicase DNA binding protein 70.722
Esr1estrogen receptor 1 (alpha)0.722
Myod1myogenic differentiation 10.716
Wnt5awingless-related MMTV integration site 5A0.713
Kitkit oncogene0.710
Ror2receptor tyrosine kinase-like orphan receptor 20.705
Tbx2T-box 20.704
Csf1colony stimulating factor 1 (macrophage)0.703
Gdnfglial cell line derived neurotrophic factor0.702
CrebbpCREB binding protein0.698
Wnt3awingless-related MMTV integration site 3A0.696
Krt5keratin 50.694
Gpc3glypican 30.688
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.653
Tgfb2transforming growth factor, beta 20.643
Gli2GLI-Kruppel family member GLI20.641
Nodalnodal0.633
JunJun oncogene0.626
Ntf3neurotrophin 30.623
Lhx1LIM homeobox protein 10.622
Hes1hairy and enhancer of split 1 (Drosophila)0.617
Hoxa13homeobox A130.610
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.607
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.600
Epas1endothelial PAS domain protein 10.591
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Junbjun B proto-oncogene0.472
Krt18keratin 180.180
Egr1early growth response 10.159
Errfi1ERBB receptor feedback inhibitor 10.082
Cald1caldesmon 10.078
CblCas-Br-M (murine) ecotropic retroviral transforming sequence0.071
Nfyanuclear transcription factor-Y alpha0.057
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.053
Ier3immediate early response 30.041
Gna12guanine nucleotide binding protein (G protein) alpha 120.035
Jak1Janus kinase 10.035
RGD1564560similar to RCK0.034
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.033
Marcksmyristoylated alanine rich protein kinase C substrate0.032
Vegfavascular endothelial growth factor A0.029
Sp1Sp1 transcription factor0.029
Zfp36zinc finger protein 360.029
Jarid1ajumonji, AT rich interactive domain 1A (Rbp2 like)0.026
Stk3serine/threonine kinase 3 (STE20 homolog, yeast)0.026
Tgfbr2transforming growth factor, beta receptor II0.026
Foxe3forkhead box E30.025
Nab1Ngfi-A binding protein 10.025
CebpdCCAAT/enhancer binding protein (C/EBP), delta0.025
Cyth1cytohesin 10.025
JunJun oncogene0.024
Smad7SMAD family member 70.024
Hnrnplheterogeneous nuclear ribonucleoprotein L0.023
Arf5ADP-ribosylation factor 50.022
Ptpn12protein tyrosine phosphatase, non-receptor type 120.022
Hfehemochromatosis0.021
RGD1309414similar to KIAA0913 protein0.021
Cd38CD38 molecule0.020
Bmp4bone morphogenetic protein 40.020
Add3adducin 3 (gamma)0.020
Foxo1forkhead box O10.020
Mapk1mitogen activated protein kinase 10.019
Zbtb41zinc finger and BTB domain containing 410.019
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.019
Cpne3copine III0.019
Slco2b1solute carrier organic anion transporter family, member 2b10.019
Sf1splicing factor 10.018
Dusp1dual specificity phosphatase 10.018
St13suppression of tumorigenicity 130.018
Casp1caspase 10.018
Nr2f2nuclear receptor subfamily 2, group F, member 20.018
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.018
Picalmphosphatidylinositol binding clathrin assembly protein0.017
Krt19keratin 190.017
RGD1310351similar to RIKEN cDNA 4732418C070.017
Cpb1carboxypeptidase B1 (tissue)0.017
Ash1lash1 (absent, small, or homeotic)-like (Drosophila)0.017
Btg2BTG family, member 20.017
Akap1A kinase (PRKA) anchor protein 10.016
Kif15kinesin family member 150.016
Hspa1aheat shock 70kD protein 1A0.016
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.016
Bmp7bone morphogenetic protein 70.016
Wipf1WAS/WASL interacting protein family, member 10.016
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.016
GperG protein-coupled estrogen receptor 10.016
Cyfip1cytoplasmic FMR1 interacting protein 10.016
Cyb5r1cytochrome b5 reductase 10.016
Sdc3syndecan 30.016
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.016
Bglapbone gamma-carboxyglutamate (gla) protein0.015
FosFBJ osteosarcoma oncogene0.015
Prkcaprotein kinase C, alpha0.015
Epcamepithelial cell adhesion molecule0.015
Slc44a4solute carrier family 44, member 40.015
Itga1integrin, alpha 10.015
Fmr1fragile X mental retardation 10.015
Nfianuclear factor I/A0.015
Mpripmyosin phosphatase Rho interacting protein0.015
Socs2suppressor of cytokine signaling 20.014
Cpsf2cleavage and polyadenylation specific factor 20.014
MgaMAX gene associated0.014
Vdac1voltage-dependent anion channel 10.014
Adam9ADAM metallopeptidase domain 9 (meltrin gamma)0.014
Sppl2asignal peptide peptidase-like 2A0.014
Casp3caspase 30.014
Mapk6mitogen-activated protein kinase 60.014
Aqp9aquaporin 90.014
Zbtb20zinc finger and BTB domain containing 200.014
Trim23tripartite motif-containing 230.014
Fosl2fos-like antigen 20.013
Vhlvon Hippel-Lindau tumor suppressor0.013
Ube2aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.013
Bat2d1BAT2 domain containing 10.013
Kcnj16potassium inwardly-rectifying channel, subfamily J, member 160.013
Dhx30DEAH (Asp-Glu-Ala-His) box polypeptide 300.013
Fkbp4FK506 binding protein 40.013
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.013
Cpb2carboxypeptidase B2 (plasma)0.013
Cishcytokine inducible SH2-containing protein0.013
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.013
Pyypeptide YY (mapped)0.013
A1bgalpha-1-B glycoprotein0.012
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.012
Gdf15growth differentiation factor 150.012
WaslWiskott-Aldrich syndrome-like0.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism