The network for 'positive regulation of axon extension' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of axon extension

Any process that activates or increases the frequency, rate or extent of axon extension.

NameDescriptionProbabilityFunc Analog Organism
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.999
APCadenomatous polyposis coli0.990
FLNAfilamin A, alpha0.983
NRP1neuropilin 10.943
VEGFAvascular endothelial growth factor A0.942
FYNFYN oncogene related to SRC, FGR, YES0.806
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.802
ITGB4integrin, beta 40.722
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.680
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.603
BCAR1breast cancer anti-estrogen resistance 10.582
CBX1chromobox homolog 10.514
ATXN1ataxin 10.487
LRRK2leucine-rich repeat kinase 20.462
MKL1megakaryoblastic leukemia (translocation) 10.458
NTRK1neurotrophic tyrosine kinase, receptor, type 10.443
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.436
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.424
FN1fibronectin 10.415
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.371
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.338
PRKG1protein kinase, cGMP-dependent, type I0.292
SPTBN1spectrin, beta, non-erythrocytic 10.283
GSK3Bglycogen synthase kinase 3 beta0.267
CFL1cofilin 1 (non-muscle)0.242
FLNBfilamin B, beta0.225
SIN3ASIN3 homolog A, transcription regulator (yeast)0.223
DCTN1dynactin 10.196
MYOD1myogenic differentiation 10.194
CAPZBcapping protein (actin filament) muscle Z-line, beta0.189
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.181
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.175
ATF7IPactivating transcription factor 7 interacting protein0.169
CDK9cyclin-dependent kinase 90.149
STRN3striatin, calmodulin binding protein 30.145
MARK1MAP/microtubule affinity-regulating kinase 10.143
MAPK8mitogen-activated protein kinase 80.141
ELOVL1elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 10.139
DCCdeleted in colorectal carcinoma0.139
CBX5chromobox homolog 50.134
RAB11FIP1RAB11 family interacting protein 1 (class I)0.132
MYH9myosin, heavy chain 9, non-muscle0.130
DPP4dipeptidyl-peptidase 40.127
MKL2MKL/myocardin-like 20.122
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.121
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.117
FYBFYN binding protein0.117
LMNAlamin A/C0.114
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.113
SNCAIPsynuclein, alpha interacting protein0.108
MYOGmyogenin (myogenic factor 4)0.108
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.105
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.104
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.104
PVRpoliovirus receptor0.104
ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)0.103
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.102
DISC1disrupted in schizophrenia 10.102
TNIKTRAF2 and NCK interacting kinase0.094
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.088
LRP6low density lipoprotein receptor-related protein 60.088
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.087
JAG2jagged 20.086
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.086
GFI1Bgrowth factor independent 1B transcription repressor0.086
FOSL1FOS-like antigen 10.085
RSU1Ras suppressor protein 10.077
ILKintegrin-linked kinase0.077
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.076
TRIOtriple functional domain (PTPRF interacting)0.076
PTPN1protein tyrosine phosphatase, non-receptor type 10.075
IQGAP1IQ motif containing GTPase activating protein 10.073
NCOR2nuclear receptor corepressor 20.072
ACVR1activin A receptor, type I0.072
BICD1bicaudal D homolog 1 (Drosophila)0.069
CTGFconnective tissue growth factor0.068
NINninein (GSK3B interacting protein)0.068
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.067
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.067
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.066
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.066
BMPR1Abone morphogenetic protein receptor, type IA0.065
PIAS2protein inhibitor of activated STAT, 20.062
PDLIM7PDZ and LIM domain 7 (enigma)0.062
CLIP1CAP-GLY domain containing linker protein 10.061
MMP14matrix metallopeptidase 14 (membrane-inserted)0.060
FLIIflightless I homolog (Drosophila)0.057
NRXN1neurexin 10.057
SYVN1synovial apoptosis inhibitor 1, synoviolin0.055
LTBP4latent transforming growth factor beta binding protein 40.055
ACTN1actinin, alpha 10.054
LIMS1LIM and senescent cell antigen-like domains 10.053
MACF1microtubule-actin crosslinking factor 10.052
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.052
SIAH1seven in absentia homolog 1 (Drosophila)0.051
ARL6IP1ADP-ribosylation factor-like 6 interacting protein 10.051
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-9Protein UNC-90.092
lin-17Protein LIN-170.077
ceh-20Protein CEH-200.047
somi-1Protein SOMI-10.045
egl-23Protein EGL-230.038
sax-3Protein SAX-30.038
acy-1Protein ACY-10.035
trim-9Protein TRIM-90.032
unc-40Protein UNC-400.030
let-413Protein LET-4130.028
pry-1Protein PRY-10.026
C11H1.3Protein C11H1.30.025
pha-4Protein PHA-40.024
sea-2Protein SEA-20.022
cwn-1Protein CWN-10.022
igcm-3Protein IGCM-30.021
tmc-2Protein TMC-20.021
cdh-3Protein CDH-30.020
F52G3.1Protein F52G3.10.020
tag-294Protein TAG-2940.019
unc-41Protein UNC-410.019
C46C11.3Protein C46C11.30.019
egl-30Protein EGL-300.019
jmjd-3.1Protein JMJD-3.10.018
F09A5.4Protein F09A5.40.017
ain-1Protein AIN-10.017
C27H2.2Protein C27H2.20.017
eva-1Protein EVA-10.017
ptp-1Protein PTP-10.016
vab-1Protein VAB-10.016
unc-86Protein UNC-860.015
lact-5Protein LACT-50.015
tag-303Protein TAG-3030.014
rpy-1Protein RPY-10.014
nhr-25Protein NHR-250.014
C35C5.6Protein C35C5.60.014
fmi-1Protein FMI-10.014
syd-9Protein SYD-90.013
shn-1Protein SHN-10.013
C05D10.4Protein C05D10.40.013
hbl-1Protein HBL-10.013
secs-1Protein SECS-10.013
inx-3Protein INX-30.013
rhgf-2Protein RHGF-20.013
fbn-1Protein FBN-10.012
F28E10.1Protein F28E10.10.012
ztf-19Protein ZTF-190.012
zoo-1Protein ZOO-10.012
elt-6Protein ELT-60.012
unc-53Protein UNC-530.012
asd-2Protein ASD-20.012
nsy-4Protein NSY-40.012
egl-18Protein EGL-180.011
egl-13Protein EGL-130.011
H11E01.3Protein H11E01.30.011
syg-2Protein SYG-20.011
rhgf-1Protein RHGF-10.011
snf-11Protein SNF-110.011
K10D6.2Protein K10D6.20.011
grl-1Protein GRL-10.010
kal-1Protein KAL-10.010
syg-1Protein SYG-10.010
attf-4Protein ATTF-40.010
mrck-1Protein MRCK-10.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cdh6cadherin 60.306
nrp1aneuropilin 1a0.137
slit3slit (Drosophila) homolog 30.113
phox2bpaired-like homeobox 2b0.105
slit1bslit homolog 1b (Drosophila)0.104
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.097
nrg2aneuregulin 2a0.089
sst1.1somatostatin 1, tandem duplicate 10.085
otx5orthodenticle homolog 50.085
mapk3mitogen-activated protein kinase 30.068
phox2apaired-like homeobox 2a0.063
nrp2bneuropilin 2b0.063
bmpr2abone morphogenetic protein receptor, type II a (serine/threonine kinase)0.060
ebf3early B-cell factor 30.050
cntn2contactin 20.045
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.043
nrp2aneuropilin 2a0.040
pdlim4PDZ and LIM domain 40.036
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.031
cdh5cadherin 50.025
robo2roundabout homolog 20.022
kdrlkinase insert domain receptor like0.021
pdlim2PDZ and LIM domain 2 (mystique)0.021
kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.020
slit1aslit homolog 1a (Drosophila)0.020
aplnrbapelin receptor b0.019
igfbp3insulin-like growth factor binding protein 30.018
myf5myogenic factor 50.017
ptpraprotein tyrosine phosphatase, receptor type, A0.017
pdlim5PDZ and LIM domain 50.016
nxph1neurexophilin 10.016
limk2LIM domain kinase 20.015
sox10SRY-box containing gene 100.015
myod1myogenic differentiation 10.015
atoh7atonal homolog 70.014
crxcone-rod homeobox0.014
vcanbversican b0.013
lhx2bLIM homeobox 2b0.013
evx1even-skipped homeobox 10.012
slit2slit (Drosophila) homolog 20.012
efna2ephrin A20.012
kal1aKallmann syndrome 1a sequence0.012
tbx20T-box 200.011
hmx2H6 family homeobox 20.011
neurodneurogenic differentiation0.011
cntn1acontactin 1a0.010
cntn1bcontactin 1b0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.710
Fas2Fasciclin 20.653
trioCG18214 gene product from transcript CG18214-RA0.600
endoAendophilin A0.405
DscamDown syndrome cell adhesion molecule0.371
stanstarry night0.255
futschCG34387 gene product from transcript CG34387-RC0.210
Sema-1aCG18405 gene product from transcript CG18405-RD0.190
AblAbl tyrosine kinase0.166
TBPHCG10327 gene product from transcript CG10327-RC0.155
Nrx-IVNeurexin IV0.149
Pi3K92ECG4141 gene product from transcript CG4141-RB0.126
KhcKinesin heavy chain0.124
RalaRas-related protein0.102
AcslAcyl-CoA synthetase long-chain0.100
DadDaughters against dpp0.097
CaMKIICalcium/calmodulin-dependent protein kinase II0.096
jingCG9397 gene product from transcript CG9397-RI0.089
robo3CG5423 gene product from transcript CG5423-RA0.079
stcksteamer duck0.075
CapsCalcium activated protein for secretion0.073
Gyc76CGuanylyl cyclase at 76C0.070
Dhc64CDynein heavy chain 64C0.069
MicalMolecule interacting with CasL0.065
Wnt5Wnt oncogene analog 50.064
beta-Specbeta Spectrin0.057
sqhspaghetti squash0.055
sec5CG8843 gene product from transcript CG8843-RA0.051
par-1CG8201 gene product from transcript CG8201-RA0.051
neuroliginCG13772 gene product from transcript CG13772-RA0.046
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.045
Trim9CG31721 gene product from transcript CG31721-RB0.043
CG12424CG12424 gene product from transcript CG12424-RC0.039
Ptp69DProtein tyrosine phosphatase 69D0.039
lolalongitudinals lacking0.039
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.038
DAAMDishevelled Associated Activator of Morphogenesis0.038
fz2frizzled 20.038
reporeversed polarity0.037
PvrPDGF- and VEGF-receptor related0.034
spensplit ends0.034
Sra-1specifically Rac1-associated protein 10.030
Dap160Dynamin associated protein 1600.030
wbwing blister0.030
jebjelly belly0.030
Syx1ASyntaxin 1A0.029
Wnt4Wnt oncogene analog 40.029
vvlventral veins lacking0.029
Ten-mTenascin major0.028
mbcmyoblast city0.027
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ntf3neurotrophin 30.999
Foxc1forkhead box C10.998
Bdnfbrain derived neurotrophic factor0.998
Tgfb2transforming growth factor, beta 20.990
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.983
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.978
Ctnnb1catenin (cadherin associated protein), beta 10.976
Foxc2forkhead box C20.974
Tgfbr2transforming growth factor, beta receptor II0.969
Nos3nitric oxide synthase 3, endothelial cell0.965
Apcadenomatosis polyposis coli0.962
Hand2heart and neural crest derivatives expressed transcript 20.957
Tcfap2atranscription factor AP-2, alpha0.952
Fgf8fibroblast growth factor 80.935
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.921
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.917
Gli3GLI-Kruppel family member GLI30.912
Tbx1T-box 10.901
Prrx1paired related homeobox 10.901
Shhsonic hedgehog0.891
Fgfr1fibroblast growth factor receptor 10.888
Fbn1fibrillin 10.871
Ptpn11protein tyrosine phosphatase, non-receptor type 110.860
Itgb1integrin beta 1 (fibronectin receptor beta)0.852
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.845
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.831
Fgfr2fibroblast growth factor receptor 20.824
Ednraendothelin receptor type A0.820
Gsk3bglycogen synthase kinase 3 beta0.799
Hoxa1homeobox A10.749
Isl1ISL1 transcription factor, LIM/homeodomain0.738
Dccdeleted in colorectal carcinoma0.722
Nrg1neuregulin 10.702
Pitx2paired-like homeodomain transcription factor 20.691
Retret proto-oncogene0.656
Sox9SRY-box containing gene 90.655
Ece1endothelin converting enzyme 10.650
Eya1eyes absent 1 homolog (Drosophila)0.637
Efnb2ephrin B20.637
Bmp4bone morphogenetic protein 40.634
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.583
Jag1jagged 10.557
Trp63transformation related protein 630.539
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.518
Unc5cunc-5 homolog C (C. elegans)0.516
Emx1empty spiracles homolog 1 (Drosophila)0.443
Phox2apaired-like homeobox 2a0.431
Plxnd1plexin D10.421
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.405
Hey2hairy/enhancer-of-split related with YRPW motif 20.394
Nrp1neuropilin 10.386
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.364
Col1a1collagen, type I, alpha 10.362
Otx2orthodenticle homolog 2 (Drosophila)0.329
Pax3paired box gene 30.319
Psen1presenilin 10.313
Rxraretinoid X receptor alpha0.310
Egfrepidermal growth factor receptor0.302
Flt4FMS-like tyrosine kinase 40.302
Kdrkinase insert domain protein receptor0.299
Cdh5cadherin 50.291
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.279
Smosmoothened homolog (Drosophila)0.277
Vegfavascular endothelial growth factor A0.271
Bmp2bone morphogenetic protein 20.267
Foxg1forkhead box G10.265
Prrx2paired related homeobox 20.260
Esr1estrogen receptor 1 (alpha)0.260
Nf1neurofibromatosis 10.260
Lrp1low density lipoprotein receptor-related protein 10.242
Slit2slit homolog 2 (Drosophila)0.239
Dlg4discs, large homolog 4 (Drosophila)0.229
Smad4MAD homolog 4 (Drosophila)0.229
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.219
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.211
Ptk2PTK2 protein tyrosine kinase 20.209
Robo1roundabout homolog 1 (Drosophila)0.206
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.204
Pbx1pre B-cell leukemia transcription factor 10.203
Gja1gap junction protein, alpha 10.196
Slit3slit homolog 3 (Drosophila)0.191
Ptprbprotein tyrosine phosphatase, receptor type, B0.179
Rdh10retinol dehydrogenase 10 (all-trans)0.172
Spna2spectrin alpha 20.171
Notch2Notch gene homolog 2 (Drosophila)0.163
Ntn1netrin 10.161
Nos1nitric oxide synthase 1, neuronal0.159
Vti1avesicle transport through interaction with t-SNAREs homolog 1A (yeast)0.159
Smad3MAD homolog 3 (Drosophila)0.153
Ddr2discoidin domain receptor family, member 20.152
Meox2mesenchyme homeobox 20.149
Rarbretinoic acid receptor, beta0.149
Nr2f1nuclear receptor subfamily 2, group F, member 10.144
Hoxa3homeobox A30.141
Epha3Eph receptor A30.140
Fbln1fibulin 10.139
Bmp7bone morphogenetic protein 70.137
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nfibnuclear factor I/B0.086
C1rcomplement component 1, r subcomponent0.062
Dlgap3discs, large (Drosophila) homolog-associated protein 30.042
Cst3cystatin C0.030
Zmym2zinc finger, MYM-type 20.029
Klc1kinesin light chain 10.029
Nrxn1neurexin 10.025
Srrm2serine/arginine repetitive matrix 20.020
Pxdnperoxidasin homolog (Drosophila)0.019
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.016
Cckbrcholecystokinin B receptor0.015
Arnt2aryl hydrocarbon receptor nuclear translocator 20.014
Klf13Kruppel-like factor 130.014
Ppap2bphosphatidic acid phosphatase type 2B0.014
Prkceprotein kinase C, epsilon0.013
Falzfetal Alzheimer antigen0.013
Tmod2tropomodulin 20.012
Znf644zinc finger protein 6440.012
Timp2TIMP metallopeptidase inhibitor 20.011
Tcf4transcription factor 40.011
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.011
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.011
Ftlferritin, light polypeptide0.011
Asap1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.011
Camk2gcalcium/calmodulin-dependent protein kinase II gamma0.010
Igf1insulin-like growth factor 10.010
Fstl1follistatin-like 10.010
Stxbp1syntaxin binding protein 10.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism