The network for 'regulation of catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
sem-5Protein SEM-50.598
hgrs-1Protein HGRS-10.369
rme-4Protein RME-40.349
egl-18Protein EGL-180.312
bet-2Protein BET-20.236
stam-1Protein STAM-10.217
unc-45Protein UNC-450.212
air-1Protein AIR-10.199
mrck-1Protein MRCK-10.197
CELE_F47G4.4Protein F47G4.40.194
daf-3Protein DAF-30.192
daf-1Protein DAF-10.191
sma-6Protein SMA-60.183
scd-1Protein SCD-10.180
daf-4Protein DAF-40.179
skn-1Protein SKN-10.179
tam-1Protein TAM-10.178
gpr-1Protein GPR-10.174
unc-62Protein UNC-620.174
rab-5Protein RAB-50.172
rpn-7Protein RPN-70.172
lag-1Protein LAG-10.169
cks-1Protein CKS-10.166
imb-2Protein IMB-20.163
atx-3Protein ATX-30.162
lsy-2Protein LSY-20.157
sel-2Protein SEL-20.155
goa-1Protein GOA-10.155
hmr-1Protein HMR-10.153
CELE_F25B4.5Protein F25B4.50.151
egl-13Protein EGL-130.148
mcm-7Protein MCM-70.146
trcs-2Protein TRCS-20.145
zoo-1Protein ZOO-10.133
miro-1Protein MIRO-10.133
mel-11Protein MEL-110.133
jnk-1Protein JNK-10.133
cki-2Protein CKI-20.133
rpn-6.1Protein RPN-6.10.128
cul-1Protein CUL-10.128
par-5Protein PAR-50.122
ifg-1Protein IFG-10.121
C11E4.6Protein C11E4.60.119
sur-2Protein SUR-20.119
ztf-7Protein ZTF-70.119
glit-1Protein GLIT-10.119
CELE_Y69A2AR.16Protein Y69A2AR.160.117
tpxl-1Protein TPXL-10.117
M88.7Protein M88.70.114
pabp-2Protein PABP-20.114
tag-343Protein TAG-3430.112
stau-1Protein STAU-10.112
smp-1Protein SMP-10.111
T23F11.1Protein T23F11.10.109
sea-2Protein SEA-20.108
ect-2Protein ECT-20.105
egl-8Protein EGL-80.105
unc-52Protein UNC-520.104
obr-3Protein OBR-30.102
R11A8.7Protein R11A8.70.102
vps-28Protein VPS-280.102
cand-1Protein CAND-10.101
rhgf-2Protein RHGF-20.100
smk-1Protein SMK-10.100
abts-1Protein ABTS-10.100
ykt-6Protein YKT-60.098
pat-12Protein PAT-120.096
csn-3Protein CSN-30.095
unc-70Protein UNC-700.095
dpy-31Protein DPY-310.095
itr-1Protein ITR-10.094
sli-1Protein SLI-10.094
mom-5Protein MOM-50.094
mtm-3Protein MTM-30.094
eor-1Protein EOR-10.094
CELE_B0285.4Protein B0285.40.093
mpk-1Protein MPK-10.090
sax-3Protein SAX-30.088
mex-5Protein MEX-50.087
unc-16Protein UNC-160.086
lin-45Protein LIN-450.086
ape-1Protein APE-10.085
atg-7Protein ATG-70.085
trr-1Protein TRR-10.083
let-60Protein LET-600.082
unc-14Protein UNC-140.081
sop-3Protein SOP-30.081
pde-4Protein PDE-40.080
ajm-1Protein AJM-10.080
sup-17Protein SUP-170.079
atg-11Protein ATG-110.079
arf-3Protein ARF-30.076
bar-1Protein BAR-10.076
F31C3.2Protein F31C3.20.076
CELE_Y57G11C.3Protein Y57G11C.30.076
madf-5Protein MADF-50.075
atg-2Protein ATG-20.075
gap-2Protein GAP-20.075
ttx-1Protein TTX-10.073
daf-14Protein DAF-140.073
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sox9aSRY-box containing gene 9a0.015
tnni2a.4troponin I, skeletal, fast 2a.40.014
sox32SRY-box containing gene 320.014
tbx1T-box 10.013
pcnaproliferating cell nuclear antigen0.012
chdchordin0.012
vangl2vang-like 2 (van gogh, Drosophila)0.011
ccnb1cyclin B10.011
acvr1bactivin A receptor, type IB0.011
bmp2bbone morphogenetic protein 2b0.011
arnt2aryl hydrocarbon receptor nuclear translocator 20.011
sox9bSRY-box containing gene 9b0.010
s1pr2sphingosine-1-phosphate receptor 20.010
itgb1bintegrin, beta 1b0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.998
Pi3K92ECG4141 gene product from transcript CG4141-RB0.996
Akt1CG4006 gene product from transcript CG4006-RA0.931
Stat92ESignal-transducer and activator of transcription protein at 92E0.921
InRInsulin-like receptor0.893
MadMothers against dpp0.881
NNotch0.869
PtenCG5671 gene product from transcript CG5671-RB0.832
Atg18Autophagy-specific gene 180.822
G-ialpha65AG protein alphai subunit 65A0.788
ttktramtrack0.780
Rho1CG8416 gene product from transcript CG8416-RB0.763
rlrolled0.757
SNF1ASNF1A/AMP-activated protein kinase0.727
Dcr-2Dicer-20.723
stgstring0.713
Hnf4Hepatocyte nuclear factor 40.710
RhebCG1081 gene product from transcript CG1081-RA0.701
giggigas0.687
CG11347CG11347 gene product from transcript CG11347-RE0.670
Atg2Autophagy-specific gene 20.669
mtsmicrotubule star0.655
Plc21CPhospholipase C at 21C0.650
RanGapRan GTPase activating protein0.646
saxsaxophone0.627
PknProtein kinase related to protein kinase N0.625
Rpd3CG7471 gene product from transcript CG7471-RA0.624
smosmoothened0.619
Atg1Autophagy-specific gene 10.616
TER94CG2331 gene product from transcript CG2331-RA0.606
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.604
SmoxSmad on X0.603
KhcKinesin heavy chain0.574
pucpuckered0.574
Atg8aAutophagy-specific gene 8a0.565
tkvthickveins0.559
neurneuralized0.558
tefutelomere fusion0.556
CycACyclin A0.536
mysmyospheroid0.520
Pi3K59FPhosphotidylinositol 3 kinase 59F0.501
mspsmini spindles0.499
SF2CG6987 gene product from transcript CG6987-RA0.497
nejnejire0.493
spinspinster0.492
drkdownstream of receptor kinase0.490
twstwins0.472
unc-104CG8566 gene product from transcript CG8566-RB0.468
Rbp6RNA-binding protein 60.461
msnmisshapen0.456
trpmltransient receptor potential mucolipin0.454
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.453
CSN4COP9 complex homolog subunit 40.452
Fmr1CG6203 gene product from transcript CG6203-RC0.450
SodSuperoxide dismutase0.449
EcREcdysone receptor0.447
MntCG13316 gene product from transcript CG13316-RD0.432
StamSignal transducing adaptor molecule0.430
nwknervous wreck0.427
cenG1Acentaurin gamma 1A0.427
dcodiscs overgrown0.425
p53CG33336 gene product from transcript CG33336-RB0.423
prodproliferation disrupter0.417
BEAF-32Boundary element-associated factor of 32kD0.410
bifbifocal0.406
drprdraper0.406
bskbasket0.375
Sir2CG5216 gene product from transcript CG5216-RA0.375
Mmp1Matrix metalloproteinase 10.370
Tsc1CG6147 gene product from transcript CG6147-RA0.369
jarjaguar0.369
CG2924CG2924 gene product from transcript CG2924-RA0.368
SbfSET domain binding factor0.361
carcarnation0.359
RagACG11968 gene product from transcript CG11968-RA0.357
p38bCG7393 gene product from transcript CG7393-RA0.354
stumpsCG31317 gene product from transcript CG31317-RC0.351
Cul-4Cullin-40.351
plexBplexin B0.342
Dhc64CDynein heavy chain 64C0.330
dysdysfusion0.324
Vha55Vacuolar H[+]-ATPase 55kD B subunit0.322
bazbazooka0.321
koiklaroid0.319
Zyx102EFCG32018 gene product from transcript CG32018-RA0.317
Su(H)Suppressor of Hairless0.316
CG3680CG3680 gene product from transcript CG3680-RA0.316
DabDisabled0.314
Su(dx)Suppressor of deltex0.312
Ard1Arrest defective 10.309
ththread0.308
trioCG18214 gene product from transcript CG18214-RA0.308
rapretina aberrant in pattern0.305
dltdiscs lost0.300
dncdunce0.292
chicoCG5686 gene product from transcript CG5686-RB0.289
egreiger0.288
eggeggless0.283
TlToll0.282
LanALaminin A0.281
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Mapre1microtubule-associated protein, RP/EB family, member 10.294
Homer1homer homolog 1 (Drosophila)0.249
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.205
Hk1hexokinase 10.204
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.178
Stxbp5syntaxin binding protein 5 (tomosyn)0.172
Caprin1cell cycle associated protein 10.168
Acadvlacyl-Coenzyme A dehydrogenase, very long chain0.160
Myl9myosin, light chain 9, regulatory0.156
Cyth1cytohesin 10.154
Anxa2annexin A20.148
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.144
Epas1endothelial PAS domain protein 10.142
Taglntransgelin0.140
Acta2smooth muscle alpha-actin0.138
Eef2eukaryotic translation elongation factor 20.138
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.137
Mapk9mitogen-activated protein kinase 90.135
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.134
Pja2praja 2, RING-H2 motif containing0.134
Vsnl1visinin-like 10.133
Gja1gap junction protein, alpha 10.128
Ubn2ubinuclein 20.127
Mgat5mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase0.124
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.120
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.118
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.117
Eci2enoyl-Coenzyme A delta isomerase 20.117
Arpc2actin related protein 2/3 complex, subunit 20.115
Akap1A kinase (PRKA) anchor protein 10.112
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.107
Gipgastric inhibitory polypeptide0.107
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.105
Ccr5chemokine (C-C motif) receptor 50.103
Sncasynuclein, alpha (non A4 component of amyloid precursor)0.102
Lphn2latrophilin 20.102
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.102
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.101
Capza2capping protein (actin filament) muscle Z-line, alpha 20.100
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.100
Myo1bmyosin Ib0.100
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.098
Nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.098
Mpripmyosin phosphatase Rho interacting protein0.098
Shank3SH3 and multiple ankyrin repeat domains 30.096
Csnk1g2casein kinase 1, gamma 20.094
Snap25synaptosomal-associated protein 250.092
Ear11eosinophil-associated, ribonuclease A family, member 110.092
Usf2upstream transcription factor 2, c-fos interacting0.092
Nrasneuroblastoma ras oncogene0.091
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.091
Klrb1akiller cell lectin-like receptor subfamily B, member 1A0.090
Junbjun B proto-oncogene0.089
Slc24a2solute carrier family 24 (sodium/potassium/calcium exchanger), member 20.089
Prdm2PR domain containing 2, with ZNF domain0.089
RGD1305793similar to hypothetical protein FLJ201540.087
Rap1bRAP1B, member of RAS oncogene family0.087
Racgap1Rac GTPase-activating protein 10.087
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.086
Hist1h1ahistone cluster 1, H1a0.085
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.083
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.083
Hand2heart and neural crest derivatives expressed 20.083
Ppm1bprotein phosphatase 1B, magnesium dependent, beta isoform0.083
Pla2g2cphospholipase A2, group IIC0.082
Ncanneurocan0.082
Slc25a42solute carrier family 25, member 420.081
Zfp260zinc finger protein 2600.079
Mapre3microtubule-associated protein, RP/EB family, member 30.077
Casp2caspase 20.077
Abi1abl-interactor 10.077
Sox17SRY (sex determining region Y)-box 170.076
Dlg3discs, large homolog 3 (Drosophila)0.076
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.076
Rgs19regulator of G-protein signaling 190.076
Cyb5r4cytochrome b5 reductase 40.075
Dgkadiacylglycerol kinase, alpha0.075
Tpm3tropomyosin 3, gamma0.075
Nckap1NCK-associated protein 10.074
Picalmphosphatidylinositol binding clathrin assembly protein0.074
Smg5Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)0.073
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.073
Cdk7cyclin-dependent kinase 70.073
Prrx1paired related homeobox 10.073
Gipc1GIPC PDZ domain containing family, member 10.073
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.072
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.072
Litaflipopolysaccharide-induced TNF factor0.072
Atf3activating transcription factor 30.072
Copb1coatomer protein complex, subunit beta 10.072
Ryr2ryanodine receptor 2, cardiac0.072
Snap29synaptosomal-associated protein 290.072
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.071
Irs1insulin receptor substrate 10.071
Crip2cysteine-rich protein 20.071
Cd36CD36 molecule (thrombospondin receptor)0.071
GraspGRP1 (general receptor for phosphoinositides 1)-associated scaffold protein0.070
Top2atopoisomerase (DNA) II alpha0.070
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.070
Ccnb1cyclin B10.070
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
KSP1Ksp1p0.504
PPH21Pph21p0.455
BCK1Bck1p0.443
CDC55Cdc55p0.381
RHO1Rho1p0.303
GLC7Glc7p0.302
CDC20Cdc20p0.285
HSV2Hsv2p0.246
ATG20Atg20p0.238
MIG1Mig1p0.237
CBF2Cbf2p0.229
FAR1Far1p0.223
STE11Ste11p0.213
CRZ1Crz1p0.213
HSP42Hsp42p0.208
PPZ1Ppz1p0.203
CLB3Clb3p0.200
STI1Sti1p0.196
CDC23Cdc23p0.193
MBF1Mbf1p0.192
CDC16Cdc16p0.191
BCY1Bcy1p0.190
YPT7Ypt7p0.186
BEM3Bem3p0.173
STE20Ste20p0.172
STE5Ste5p0.166
TOF2Tof2p0.164
PKH2Pkh2p0.159
GDS1Gds1p0.158
TOR1Tor1p0.157
CDC24Cdc24p0.154
KOG1Kog1p0.154
SGV1Sgv1p0.153
CAK1Cak1p0.153
DAM1Dam1p0.152
TRS65Trs65p0.152
SUI3Sui3p0.152
SNF4Snf4p0.149
SLT2Slt2p0.149
GLN3Gln3p0.144
ORC1Orc1p0.140
UBR1Ubr1p0.140
RGA2Rga2p0.138
CTF13Ctf13p0.137
IME2Ime2p0.136
HHT1Hht1p0.133
SHP1Shp1p0.133
APP1App1p0.132
FLO8Flo8p0.130
RAS2Ras2p0.128
SIP2Sip2p0.128
PKP2Pkp2p0.127
STE4Ste4p0.127
SEC4Sec4p0.127
RPO21Rpo21p0.126
ADR1Adr1p0.126
REG1Reg1p0.124
MMR1Mmr1p0.123
ERV25Erv25p0.123
NUP170Nup170p0.122
ROM2Rom2p0.122
BOI2Boi2p0.122
MAD2Mad2p0.122
SET2Set2p0.121
RPT6Rpt6p0.118
MND2Mnd2p0.117
YAK1Yak1p0.117
IML3Iml3p0.116
DCP2Dcp2p0.115
GSY2Gsy2p0.115
NEM1Nem1p0.115
EAF1Eaf1p0.115
NET1Net1p0.114
BMH2Bmh2p0.113
SGT2Sgt2p0.112
MLC1Mlc1p0.111
CLN3Cln3p0.111
TPK1Tpk1p0.111
SMC4Smc4p0.110
HSE1Hse1p0.109
CRN1Crn1p0.109
MKK1Mkk1p0.109
SWE1Swe1p0.108
MCM21Mcm21p0.106
TPK2Tpk2p0.106
ATG3Atg3p0.106
NBL1Nbl1p0.106
OKP1Okp1p0.104
CDC27Cdc27p0.104
YCR007Chypothetical protein0.104
SLI15Sli15p0.102
NTO1Nto1p0.102
HHO1Hho1p0.102
YPT31Ypt31p0.101
SCH9Sch9p0.100
SEC16Sec16p0.100
ABP1Abp1p0.099
PIG2Pig2p0.098
YPT53Ypt53p0.098
MSN5Msn5p0.097