The network for 'regulation of dephosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of dephosphorylation

Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.

NameDescriptionProbabilityFunc Analog Organism
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.998
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.953
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.923
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.915
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.893
AKT1v-akt murine thymoma viral oncogene homolog 10.887
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.757
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.720
ACTBactin, beta0.682
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.655
PPP6Cprotein phosphatase 6, catalytic subunit0.586
CDK1cyclin-dependent kinase 10.564
FHL2four and a half LIM domains 20.533
RIPK3receptor-interacting serine-threonine kinase 30.470
ANKRD28ankyrin repeat domain 280.412
PTPRCprotein tyrosine phosphatase, receptor type, C0.381
PPP6R2protein phosphatase 6, regulatory subunit 20.377
LATlinker for activation of T cells0.348
TSC2tuberous sclerosis 20.346
MAPK1mitogen-activated protein kinase 10.333
MAP3K3mitogen-activated protein kinase kinase kinase 30.314
HDAC4histone deacetylase 40.313
BIRC2baculoviral IAP repeat containing 20.312
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.310
CASC5cancer susceptibility candidate 50.304
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.304
ADORA2Aadenosine A2a receptor0.277
ZFYVE9zinc finger, FYVE domain containing 90.264
KIAA1683KIAA16830.245
TCTEX1D4Tctex1 domain containing 40.229
SH3RF1SH3 domain containing ring finger 10.227
MPRIPmyosin phosphatase Rho interacting protein0.222
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.211
SHC1SHC (Src homology 2 domain containing) transforming protein 10.198
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.189
ANKRD52ankyrin repeat domain 520.188
AFF4AF4/FMR2 family, member 40.184
BMPR1Abone morphogenetic protein receptor, type IA0.183
PTENphosphatase and tensin homolog0.183
VEGFAvascular endothelial growth factor A0.178
TSSK2testis-specific serine kinase 20.176
GDAguanine deaminase0.176
SETSET nuclear oncogene0.174
CDK2cyclin-dependent kinase 20.171
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.155
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.148
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.143
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.141
PPP6R1protein phosphatase 6, regulatory subunit 10.140
PBKPDZ binding kinase0.139
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.135
PPP1R8protein phosphatase 1, regulatory (inhibitor) subunit 80.134
NRP1neuropilin 10.134
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.131
SNF8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.128
ADRB1adrenergic, beta-1-, receptor0.123
TGFBR1transforming growth factor, beta receptor 10.121
PKM2pyruvate kinase, muscle0.121
EAF1ELL associated factor 10.120
ACVR1Bactivin A receptor, type IB0.120
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.112
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.112
FANCCFanconi anemia, complementation group C0.110
RLN3relaxin 30.110
KLHL3kelch-like 3 (Drosophila)0.104
MYO10myosin X0.098
OPTNoptineurin0.097
PPP1R10protein phosphatase 1, regulatory (inhibitor) subunit 100.095
CCNB1cyclin B10.094
TP53BP2tumor protein p53 binding protein, 20.090
FASLGFas ligand (TNF superfamily, member 6)0.090
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.088
CDHR2cadherin-related family member 20.087
PPP1CBprotein phosphatase 1, catalytic subunit, beta isozyme0.087
SFNstratifin0.086
WWP2WW domain containing E3 ubiquitin protein ligase 20.085
FN1fibronectin 10.085
TRAF1TNF receptor-associated factor 10.085
LMTK2lemur tyrosine kinase 20.084
MARK2MAP/microtubule affinity-regulating kinase 20.084
ENGendoglin0.081
TFF1trefoil factor 10.081
ZBTB16zinc finger and BTB domain containing 160.081
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.081
C11orf66chromosome 11 open reading frame 660.080
BTBD10BTB (POZ) domain containing 100.079
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.078
KIAA1949KIAA19490.077
CDC25Bcell division cycle 25 homolog B (S. pombe)0.076
NOXA1NADPH oxidase activator 10.076
EPRSglutamyl-prolyl-tRNA synthetase0.075
PPP1R13Bprotein phosphatase 1, regulatory (inhibitor) subunit 13B0.075
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.075
BIRC3baculoviral IAP repeat containing 30.073
PPP2R2Cprotein phosphatase 2, regulatory subunit B, gamma0.073
SEMA6Asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.073
PPP1R15Bprotein phosphatase 1, regulatory (inhibitor) subunit 15B0.073
PFN1profilin 10.072
RASA1RAS p21 protein activator (GTPase activating protein) 10.070
CSNK2A2casein kinase 2, alpha prime polypeptide0.070
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
C17G10.1Protein C17G10.10.011
F33G12.2Protein F33G12.20.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Rpgrip1lRpgrip1-like0.607
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.543
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.431
Leprleptin receptor0.352
Tnftumor necrosis factor0.340
Dlg4discs, large homolog 4 (Drosophila)0.333
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.330
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.289
Ifnginterferon gamma0.284
Cdk1cyclin-dependent kinase 10.183
Map3k14mitogen-activated protein kinase kinase kinase 140.121
Ltalymphotoxin A0.116
Ncoa3nuclear receptor coactivator 30.114
Lrrk2leucine-rich repeat kinase 20.110
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.108
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.094
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.092
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.091
Cdkn1bcyclin-dependent kinase inhibitor 1B0.088
Acvr1activin A receptor, type 10.082
Ccna2cyclin A20.082
Nos3nitric oxide synthase 3, endothelial cell0.076
Snap25synaptosomal-associated protein 250.073
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.071
Hdac4histone deacetylase 40.067
Ltblymphotoxin B0.064
Tsc2tuberous sclerosis 20.063
Vdrvitamin D receptor0.061
Apcadenomatosis polyposis coli0.055
Agtr2angiotensin II receptor, type 20.053
Manfmesencephalic astrocyte-derived neurotrophic factor0.051
Csf1colony stimulating factor 1 (macrophage)0.048
Nf2neurofibromatosis 20.044
Agrpagouti related protein0.043
Trp53transformation related protein 530.042
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.041
Tgfbr2transforming growth factor, beta receptor II0.040
Mef2dmyocyte enhancer factor 2D0.038
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.038
Nodalnodal0.038
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.038
Ccnb1cyclin B10.035
Cxcr5chemokine (C-X-C motif) receptor 50.033
Retret proto-oncogene0.033
Nf1neurofibromatosis 10.032
Nos1nitric oxide synthase 1, neuronal0.031
Ppargc1bperoxisome proliferative activated receptor, gamma, coactivator 1 beta0.030
Rab25RAB25, member RAS oncogene family0.030
Plk1polo-like kinase 1 (Drosophila)0.029
Qkquaking0.028
Zeb2zinc finger E-box binding homeobox 20.028
Il7interleukin 70.027
Ube2cubiquitin-conjugating enzyme E2C0.027
Mgat3mannoside acetylglucosaminyltransferase 30.027
Prc1protein regulator of cytokinesis 10.026
Calm1calmodulin 10.026
Nedd4lneural precursor cell expressed, developmentally down-regulated gene 4-like0.025
Hdac5histone deacetylase 50.024
Il10interleukin 100.024
Kif20akinesin family member 20A0.024
Cd44CD44 antigen0.023
Ptpn12protein tyrosine phosphatase, non-receptor type 120.023
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.023
Hspa1bheat shock protein 1B0.023
Toxthymocyte selection-associated high mobility group box0.022
Ighimmunoglobulin heavy chain complex0.022
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.022
Adcy9adenylate cyclase 90.022
0610031J06RikRIKEN cDNA 0610031J06 gene0.021
Plxna4plexin A40.021
9130017N09RikRIKEN cDNA 9130017N09 gene0.020
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.019
Tlr2toll-like receptor 20.019
Syn2synapsin II0.019
Ptpn11protein tyrosine phosphatase, non-receptor type 110.019
Ttntitin0.018
Hspa5heat shock protein 50.018
Hand1heart and neural crest derivatives expressed transcript 10.018
Nptx1neuronal pentraxin 10.018
Wdr45WD repeat domain 450.017
Gja1gap junction protein, alpha 10.017
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.017
Kif22kinesin family member 220.017
Pcbp1poly(rC) binding protein 10.017
Ube2e1ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast)0.017
Grngranulin0.016
Sez6lseizure related 6 homolog like0.016
Aurkaaurora kinase A0.016
Ptgs2prostaglandin-endoperoxide synthase 20.016
Col4a3collagen, type IV, alpha 30.016
Hdac7histone deacetylase 70.015
Tgfb2transforming growth factor, beta 20.015
Cxcl13chemokine (C-X-C motif) ligand 130.015
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.015
Zeb1zinc finger E-box binding homeobox 10.015
Tsr1TSR1, 20S rRNA accumulation, homolog (yeast)0.015
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.015
Fam83gfamily with sequence similarity 83, member G0.015
Scn11asodium channel, voltage-gated, type XI, alpha0.015
Ckap2cytoskeleton associated protein 20.015
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Rpl11ribosomal protein L110.021
Rps27aribosomal protein S27a0.016
Rpl10ribosomal protein L100.014
Rpsaribosomal protein SA0.014
Rps16ribosomal protein S160.013
Rpl5ribosomal protein L50.012
Rpl37ribosomal protein L370.011
Rpl22ribosomal protein L220.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SDS22Sds22p0.581
CKS1Cks1p0.355
KDX1Kdx1p0.277
RSN1Rsn1p0.104
CLB1Clb1p0.098
PPZ1Ppz1p0.079
TFG2Tfg2p0.074
CLB3Clb3p0.065
RPB11Rpb11p0.064
YPI1Ypi1p0.058
BMH2Bmh2p0.053
CAB3Cab3p0.051
PDS1Pds1p0.050
ZPR1Zpr1p0.050
SFG1Sfg1p0.048
PKC1Pkc1p0.047
OSH2Osh2p0.046
CLB5Clb5p0.045
GIP2Gip2p0.042
SIC1Sic1p0.041
CLB4Clb4p0.040
YGR210Chypothetical protein0.038
CLN1Cln1p0.037
SWE1Swe1p0.036
FIN1Fin1p0.036
RRP17Rrp17p0.034
TYW1Tyw1p0.030
PTI1Pti1p0.029
PDS5Pds5p0.029
GIP3Gip3p0.028
GLC7Glc7p0.027
FPR3Fpr3p0.025
RHO1Rho1p0.025
IST2Ist2p0.024
CDC15Cdc15p0.024
LTV1Ltv1p0.023
PPQ1Ppq1p0.022
GCS1Gcs1p0.022
ABP140Abp140p0.022
POG1Pog1p0.022
CLN2Cln2p0.021
PTC3Ptc3p0.021
KEL3Kel3p0.021
WWM1Wwm1p0.021
SOK1Sok1p0.020
GAT1Gat1p0.020
YLR264C-Ahypothetical protein0.020
PSK1Psk1p0.019
CLB6Clb6p0.019
TED1Ted1p0.019
APM1Apm1p0.019
FPK1Fpk1p0.019
HAC1Hac1p0.019
URA3Ura3p0.019
SRD1Srd1p0.019
PAN1Pan1p0.018
WSC4Wsc4p0.018
SRP54Srp54p0.018
YLR162Whypothetical protein0.018
JIP4Jip4p0.018
PTC2Ptc2p0.018
LEU2Leu2p0.018
SAS10Sas10p0.018
SUI3Sui3p0.017
KSS1Kss1p0.017
YBL086Chypothetical protein0.017
IML1Iml1p0.017
FMP48Fmp48p0.017
CLB2Clb2p0.017
PLM2Plm2p0.016
HAL5Hal5p0.016
SPC1Spc1p0.016
YNL058Chypothetical protein0.016
BCK2Bck2p0.016
YOL038C-Ahypothetical protein0.016
YDL121Chypothetical protein0.016
ARP10Arp10p0.016
GEA2Gea2p0.016
YNR014Whypothetical protein0.016
DNF1Dnf1p0.016
RHO5Rho5p0.016
YSP2Ysp2p0.016
CUP1-1Cup1-1p0.016
ARG8Arg8p0.015
OYE2Oye2p0.015
YIR035Chypothetical protein0.015
SBE22Sbe22p0.015
CDC6Cdc6p0.015
ROM1Rom1p0.015
OSH3Osh3p0.015
MF(ALPHA)2Mf(alpha)2p0.015
STU1Stu1p0.015
YDL129Whypothetical protein0.015
SSK1Ssk1p0.014
LAC1Lac1p0.014
CPD1Cpd1p0.014
UTP20Utp20p0.014
ITR2Itr2p0.014
SSP1Ssp1p0.014
SPC97Spc97p0.014