The network for 'negative regulation of interleukin 1 mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of interleukin 1 mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.

NameDescriptionProbabilityFunc Analog Organism
ZNF43zinc finger protein 431.000
ZNF675zinc finger protein 6750.999
ZNF253zinc finger protein 2530.998
ZNF273zinc finger protein 2730.995
IL1R1interleukin 1 receptor, type I0.992
ZNF91zinc finger protein 910.984
ZNF680zinc finger protein 6800.955
ZNF93zinc finger protein 930.923
ZNF85zinc finger protein 850.903
ZNF430zinc finger protein 4300.870
ZNF708zinc finger protein 7080.798
ZNF254zinc finger protein 2540.675
ZNF117zinc finger protein 1170.586
ZNF92zinc finger protein 920.423
IL1RAPinterleukin 1 receptor accessory protein0.345
IL1Binterleukin 1, beta0.325
ZNF107zinc finger protein 1070.247
IL1RNinterleukin 1 receptor antagonist0.244
DOCK7dedicator of cytokinesis 70.159
ZNF682zinc finger protein 6820.153
IL1R2interleukin 1 receptor, type II0.139
IL8interleukin 80.091
TRAF6TNF receptor-associated factor 60.090
ZNF100zinc finger protein 1000.053
ZNF136zinc finger protein 1360.051
ZNF506zinc finger protein 5060.051
MDFIMyoD family inhibitor0.049
C7orf64chromosome 7 open reading frame 640.044
CCL20chemokine (C-C motif) ligand 200.042
ZNF195zinc finger protein 1950.041
TP63tumor protein p630.040
TICAM2toll-like receptor adaptor molecule 20.039
ZNF138zinc finger protein 1380.039
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.037
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.036
CXCL2chemokine (C-X-C motif) ligand 20.035
TMSB4Xthymosin beta 4, X-linked0.034
ZNF665zinc finger protein 6650.034
ZNF493zinc finger protein 4930.034
RBAKRB-associated KRAB zinc finger0.034
ZFP30zinc finger protein 30 homolog (mouse)0.032
ZNF480zinc finger protein 4800.031
ZNF567zinc finger protein 5670.030
PI3peptidase inhibitor 3, skin-derived0.028
ZNF84zinc finger protein 840.027
CXCL3chemokine (C-X-C motif) ligand 30.025
SIKE1suppressor of IKBKE 10.025
PLAURplasminogen activator, urokinase receptor0.025
ZNF492zinc finger protein 4920.024
ANXA7annexin A70.022
SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 20.022
EXT2exostosin 20.019
ZNF320zinc finger protein 3200.019
ZNF813zinc finger protein 8130.019
TREM1triggering receptor expressed on myeloid cells 10.018
GPR109BG protein-coupled receptor 109B0.018
ZNF223zinc finger protein 2230.018
ZNF614zinc finger protein 6140.017
ZNF681zinc finger protein 6810.017
IRAK2interleukin-1 receptor-associated kinase 20.017
ARG1arginase, liver0.017
ZNF124zinc finger protein 1240.016
ZMYM5zinc finger, MYM-type 50.016
ZNF684zinc finger protein 6840.016
ZC3H12Azinc finger CCCH-type containing 12A0.016
MTERFmitochondrial transcription termination factor0.016
ZNF141zinc finger protein 1410.016
ZNF486zinc finger protein 4860.016
IL6interleukin 6 (interferon, beta 2)0.015
ZNF780Azinc finger protein 780A0.015
ZNF440zinc finger protein 4400.014
NAA16N(alpha)-acetyltransferase 16, NatA auxiliary subunit0.014
S100A8S100 calcium binding protein A80.014
ZNF347zinc finger protein 3470.013
A1BGalpha-1-B glycoprotein0.013
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.013
RFX7regulatory factor X, 70.013
ZNF816zinc finger protein 8160.013
IL1Ainterleukin 1, alpha0.013
ZNF763zinc finger protein 7630.013
IL1F9interleukin 1 family, member 90.012
ZNF10zinc finger protein 100.012
SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 130.012
CCL4chemokine (C-C motif) ligand 40.012
ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif, 100.012
ZNF700zinc finger protein 7000.012
S100A12S100 calcium binding protein A120.012
ZNF140zinc finger protein 1400.012
ZNF441zinc finger protein 4410.012
ZNF180zinc finger protein 1800.012
AQP9aquaporin 90.012
ZNF426zinc finger protein 4260.012
CA14carbonic anhydrase XIV0.012
ZNF260zinc finger protein 2600.011
BCL2A1BCL2-related protein A10.011
TRIM24tripartite motif containing 240.011
ZNF345zinc finger protein 3450.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism