The network for 'cell cell junction maintenance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell cell junction maintenance

The maintenance of junctions between cells.

NameDescriptionProbabilityFunc Analog Organism
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.847
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.719
CDH5cadherin 5, type 2 (vascular endothelium)0.690
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.608
VEGFAvascular endothelial growth factor A0.511
PDGFAplatelet-derived growth factor alpha polypeptide0.489
KITLGKIT ligand0.346
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.296
GAB1GRB2-associated binding protein 10.273
LATlinker for activation of T cells0.270
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.249
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.215
PDGFCplatelet derived growth factor C0.168
PLCG1phospholipase C, gamma 10.123
LLGL2lethal giant larvae homolog 2 (Drosophila)0.107
NRP1neuropilin 10.107
BCAR1breast cancer anti-estrogen resistance 10.105
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.080
FGFR1fibroblast growth factor receptor 10.074
PGFplacental growth factor0.071
SOS1son of sevenless homolog 1 (Drosophila)0.071
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.064
PRKCZprotein kinase C, zeta0.061
ACAP3ArfGAP with coiled-coil, ankyrin repeat and PH domains 30.055
PLCB3phospholipase C, beta 3 (phosphatidylinositol-specific)0.053
GAB2GRB2-associated binding protein 20.040
PTPRJprotein tyrosine phosphatase, receptor type, J0.036
AXLAXL receptor tyrosine kinase0.035
SOCS6suppressor of cytokine signaling 60.033
C10orf118chromosome 10 open reading frame 1180.032
CMIPc-Maf-inducing protein0.031
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.031
LDLRlow density lipoprotein receptor0.030
CTNND1catenin (cadherin-associated protein), delta 10.030
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.028
TEAD3TEA domain family member 30.025
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.025
KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.025
SHC2SHC (Src homology 2 domain containing) transforming protein 20.025
KIF3Akinesin family member 3A0.025
GTPBP5GTP binding protein 5 (putative)0.022
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.022
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.021
CD33CD33 molecule0.021
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.021
EGFRepidermal growth factor receptor0.020
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.020
PROM1prominin 10.020
SQSTM1sequestosome 10.020
LLGL1lethal giant larvae homolog 1 (Drosophila)0.020
CCDC115coiled-coil domain containing 1150.019
RAI1retinoic acid induced 10.019
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.018
ASRGL1asparaginase like 10.018
HSPG2heparan sulfate proteoglycan 20.017
ARHGEF9Cdc42 guanine nucleotide exchange factor (GEF) 90.016
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide0.016
PRKCQprotein kinase C, theta0.015
MAPTmicrotubule-associated protein tau0.015
SPTBN1spectrin, beta, non-erythrocytic 10.015
PHACTR3phosphatase and actin regulator 30.015
ENAHenabled homolog (Drosophila)0.015
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.015
MAP2microtubule-associated protein 20.015
LOC283278hypothetical protein LOC2832780.015
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.015
ZNF784zinc finger protein 7840.014
PPP1R13Bprotein phosphatase 1, regulatory (inhibitor) subunit 13B0.014
C1QAcomplement component 1, q subcomponent, A chain0.014
NRBP2nuclear receptor binding protein 20.014
PNMA1paraneoplastic antigen MA10.013
JAM3junctional adhesion molecule 30.013
INSRinsulin receptor0.013
MON1AMON1 homolog A (yeast)0.012
PLEKHA6pleckstrin homology domain containing, family A member 60.012
F13A1coagulation factor XIII, A1 polypeptide0.012
SOS2son of sevenless homolog 2 (Drosophila)0.012
F11RF11 receptor0.012
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein0.012
RHPN1rhophilin, Rho GTPase binding protein 10.012
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.011
COL1A1collagen, type I, alpha 10.011
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.011
JAM2junctional adhesion molecule 20.011
PLEKHA7pleckstrin homology domain containing, family A member 70.011
FCGR3BFc fragment of IgG, low affinity IIIb, receptor (CD16b)0.011
GGT5gamma-glutamyltransferase 50.011
CD248CD248 molecule, endosialin0.011
PTPN4protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)0.011
ARHGAP32Rho GTPase activating protein 320.010
ERGv-ets erythroblastosis virus E26 oncogene homolog (avian)0.010
CARD11caspase recruitment domain family, member 110.010
CEP350centrosomal protein 350kDa0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mbpmyelin basic protein0.390
pax7bpaired box gene 7b0.215
epb41l5erythrocyte membrane protein band 4.1 like 50.103
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.095
pnp4apurine nucleoside phosphorylase 4a0.083
trpm7transient receptor potential cation channel, subfamily M, member 70.068
ltkleukocyte tyrosine kinase0.066
guca1cguanylate cyclase activator 1C0.059
LOC100007758novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3)0.054
ntrk2bneurotrophic tyrosine kinase, receptor, type 2b0.052
pmelapremelanosome protein a0.049
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.045
mitfamicrophthalmia-associated transcription factor a0.038
crb2acrumbs homolog 2a0.036
cdh23cadherin-like 230.035
plp1bproteolipid protein 1b0.034
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.033
synj1synaptojanin 10.032
kitakit receptor a0.031
ilkintegrin linked kinase0.028
LOC100003514protein kinase C alpha type-like0.028
gpm6bbglycoprotein M6Bb0.028
enpp6ectonucleotide pyrophosphatase/phosphodiesterase 60.026
dlg1discs, large (Drosophila) homolog 10.025
olig1oligodendrocyte lineage transcription factor 10.025
supt6hsuppressor of Ty 6 homolog0.024
mpzmyelin protein zero0.023
plxnb2aplexin b2a0.022
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.021
tuba8l3tubulin, alpha 8 like 30.019
slc45a2solute carrier family 45, member 20.018
avpr1barginine vasopressin receptor 1B0.018
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.018
st14asuppression of tumorigenicity 14 (colon carcinoma) a0.017
acp5bacid phosphatase 5b, tartrate resistant0.017
apcadenomatosis polyposis coli0.016
entpd3ectonucleoside triphosphate diphosphohydrolase 30.016
krit1KRIT1, ankyrin repeat containing0.016
grifingalectin related inter-fiber protein0.015
tjp2atight junction protein 2a (zona occludens 2)0.015
ptpraprotein tyrosine phosphatase, receptor type, A0.015
rcn1reticulocalbin 1, EF-hand calcium binding domain0.015
vaspvasodilator-stimulated phosphoprotein0.015
prkczprotein kinase C, zeta0.015
csadcysteine sulfinic acid decarboxylase0.015
ntrk2aneurotrophic tyrosine kinase, receptor, type 2a0.014
slc6a4asolute carrier family 6 (neurotransmitter transporter, serotonin), member 4A0.014
sardhsarcosine dehydrogenase0.014
waslbWiskott-Aldrich syndrome-like b0.014
nadl1.1neural adhesion molecule L1.10.014
bnc2basonuclin 20.013
ptgdsprostaglandin D2 synthase0.013
fasFas (TNF receptor superfamily, member 6)0.013
mgpmatrix Gla protein0.013
ighzimmunoglobulin heavy constant zeta0.012
slc24a5solute carrier family 24, member 50.012
tnfatumor necrosis factor a (TNF superfamily, member 2)0.012
dlg4discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)0.012
adipor1badiponectin receptor 1b0.011
sox10SRY-box containing gene 100.011
drgxdorsal root ganglia homeobox0.011
dpysl2bdihydropyrimidinase-like 2b0.011
prkcbbprotein kinase C, beta b0.011
rpe65bretinal pigment epithelium-specific protein 65b0.011
lamb2llaminin, beta 2-like0.010
atp6v0d1ATPase, H+ transporting, V0 subunit D isoform 10.010
stc1lstanniocalcin 1, like0.010
b3galt2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 20.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.122
phlpole hole0.043
EgfrEpidermal growth factor receptor0.030
EcREcdysone receptor0.012
E(z)Enhancer of zeste0.011
Rho1CG8416 gene product from transcript CG8416-RB0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Csf1colony stimulating factor 1 (macrophage)0.552
TyrobpTYRO protein tyrosine kinase binding protein0.206
C1qbcomplement component 1, q subcomponent, beta polypeptide0.107
Vhlvon Hippel-Lindau tumor suppressor0.105
Cdh1cadherin 10.073
C1qacomplement component 1, q subcomponent, alpha polypeptide0.059
C1qccomplement component 1, q subcomponent, C chain0.057
Ly86lymphocyte antigen 860.038
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.033
Ripk4receptor-interacting serine-threonine kinase 40.030
Fam83hfamily with sequence similarity 83, member H0.030
Lyz1lysozyme 10.029
Cdcp1CUB domain containing protein 10.027
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.026
Itga3integrin alpha 30.025
Spint1serine protease inhibitor, Kunitz type 10.022
Crb2crumbs homolog 2 (Drosophila)0.021
Wwc1WW, C2 and coiled-coil domain containing 10.020
Rhpn2rhophilin, Rho GTPase binding protein 20.020
Phlda2pleckstrin homology-like domain, family A, member 20.020
Pld4phospholipase D family, member 40.019
Aif1allograft inflammatory factor 10.019
Cd52CD52 antigen0.019
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.019
Esrp1epithelial splicing regulatory protein 10.019
Ptprfprotein tyrosine phosphatase, receptor type, F0.018
Fzd6frizzled homolog 6 (Drosophila)0.018
Dsg2desmoglein 20.017
Rassf7Ras association (RalGDS/AF-6) domain family (N-terminal) member 70.017
Baiap2l1BAI1-associated protein 2-like 10.017
Ctsscathepsin S0.017
Epha2Eph receptor A20.016
Leprleptin receptor0.016
Irf6interferon regulatory factor 60.016
Rab25RAB25, member RAS oncogene family0.016
Llgl2lethal giant larvae homolog 2 (Drosophila)0.016
Actn4actinin alpha 40.016
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.014
Lama5laminin, alpha 50.014
Esrp2epithelial splicing regulatory protein 20.014
Zfp185zinc finger protein 1850.014
9030409G11RikRIKEN cDNA 9030409G11 gene0.014
Cd151CD151 antigen0.014
Vegfavascular endothelial growth factor A0.014
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.013
Alox5aparachidonate 5-lipoxygenase activating protein0.013
Mpeg1macrophage expressed gene 10.013
Mrc1mannose receptor, C type 10.013
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.013
Fcgr3Fc receptor, IgG, low affinity III0.013
SrcRous sarcoma oncogene0.013
Grb7growth factor receptor bound protein 70.013
Dnalc4dynein, axonemal, light chain 40.012
Krt7keratin 70.012
Celsr1cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)0.012
Tuft1tuftelin 10.012
Nphs2nephrosis 2 homolog, podocin (human)0.012
Tgfb1transforming growth factor, beta 10.012
H2-Aahistocompatibility 2, class II antigen A, alpha0.012
Pak4p21 protein (Cdc42/Rac)-activated kinase 40.012
Smurf2SMAD specific E3 ubiquitin protein ligase 20.012
Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)0.012
PawrPRKC, apoptosis, WT1, regulator0.011
Tjp2tight junction protein 20.011
Spint2serine protease inhibitor, Kunitz type 20.011
Cd68CD68 antigen0.011
AW555464expressed sequence AW5554640.011
Lrrc16aleucine rich repeat containing 16A0.011
PerpPERP, TP53 apoptosis effector0.011
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.011
Tmem30btransmembrane protein 30B0.011
Mpzl2myelin protein zero-like 20.011
Pard6bpar-6 (partitioning defective 6) homolog beta (C. elegans)0.011
Mtap7microtubule-associated protein 70.011
Prss8protease, serine, 8 (prostasin)0.011
Prkczprotein kinase C, zeta0.011
Krt8keratin 80.011
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.010
Itgb4integrin beta 40.010
Cyb561cytochrome b-5610.010
Unc93b1unc-93 homolog B1 (C. elegans)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism