The network for 'negative regulation of interleukin 13 secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of interleukin 13 secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-13 secretion.

NameDescriptionProbabilityFunc Analog Organism
SNAP23synaptosomal-associated protein, 23kDa0.993
IFNA4interferon, alpha 40.881
IFNA21interferon, alpha 210.692
IFNA17interferon, alpha 170.677
IFNA16interferon, alpha 160.616
IFNA10interferon, alpha 100.552
IFNA14interferon, alpha 140.544
APPamyloid beta (A4) precursor protein0.520
IFNA7interferon, alpha 70.330
TAS2R16taste receptor, type 2, member 160.249
CYLC1cylicin, basic protein of sperm head cytoskeleton 10.243
IFNA13interferon, alpha 130.206
COLEC10collectin sub-family member 10 (C-type lectin)0.139
C6orf10chromosome 6 open reading frame 100.132
GYPBglycophorin B (MNS blood group)0.080
HTN1histatin 10.070
IFNA2interferon, alpha 20.067
OR7A10olfactory receptor, family 7, subfamily A, member 100.064
OR2B2olfactory receptor, family 2, subfamily B, member 20.064
TAS2R7taste receptor, type 2, member 70.061
AFMafamin0.055
CTAGE1cutaneous T-cell lymphoma-associated antigen 10.055
HTN3histatin 30.054
TSHBthyroid stimulating hormone, beta0.054
IAPPislet amyloid polypeptide0.052
CYLC2cylicin, basic protein of sperm head cytoskeleton 20.050
STAT5Asignal transducer and activator of transcription 5A0.050
IFNA8interferon, alpha 80.049
GYPAglycophorin A (MNS blood group)0.049
OR52A1olfactory receptor, family 52, subfamily A, member 10.049
CSN1S1casein alpha s10.048
RRHretinal pigment epithelium-derived rhodopsin homolog0.048
IFNA5interferon, alpha 50.046
FGL1fibrinogen-like 10.046
STATHstatherin0.044
ANGPTL3angiopoietin-like 30.041
TRIM48tripartite motif containing 480.040
SPO11SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)0.040
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.040
SEMG2semenogelin II0.039
LIPFlipase, gastric0.038
STX11syntaxin 110.037
LUZP4leucine zipper protein 40.036
IL21interleukin 210.035
PDCphosducin0.034
PSMD5proteasome (prosome, macropain) 26S subunit, non-ATPase, 50.033
CRISP1cysteine-rich secretory protein 10.032
GNAT2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.032
TAS2R8taste receptor, type 2, member 80.032
CLDN17claudin 170.032
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.032
CSN3casein kappa0.031
SLCO1B1solute carrier organic anion transporter family, member 1B10.028
RGSL1regulator of G-protein signaling like 10.028
FSHRfollicle stimulating hormone receptor0.028
HNF4Ghepatocyte nuclear factor 4, gamma0.027
ODAModontogenic, ameloblast asssociated0.027
CSN2casein beta0.027
HIST1H3Jhistone cluster 1, H3j0.027
GCNT4glucosaminyl (N-acetyl) transferase 4, core 20.026
FABP2fatty acid binding protein 2, intestinal0.026
TAAR2trace amine associated receptor 20.026
F13Bcoagulation factor XIII, B polypeptide0.025
GPR22G protein-coupled receptor 220.025
SNTG1syntrophin, gamma 10.024
CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 10.024
MTMR7myotubularin related protein 70.024
KRTAP1-1keratin associated protein 1-10.023
NMBRneuromedin B receptor0.023
CNGB3cyclic nucleotide gated channel beta 30.023
CDH9cadherin 9, type 2 (T1-cadherin)0.023
GNGT1guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 10.023
C1orf129chromosome 1 open reading frame 1290.023
GYPEglycophorin E (MNS blood group)0.023
PDE6Hphosphodiesterase 6H, cGMP-specific, cone, gamma0.022
OMGoligodendrocyte myelin glycoprotein0.022
MORC1MORC family CW-type zinc finger 10.022
IMPG2interphotoreceptor matrix proteoglycan 20.022
HYAL4hyaluronoglucosaminidase 40.022
SPTA1spectrin, alpha, erythrocytic 1 (elliptocytosis 2)0.022
BAATbile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)0.022
ANP32Cacidic (leucine-rich) nuclear phosphoprotein 32 family, member C0.021
TNFSF18tumor necrosis factor (ligand) superfamily, member 180.021
ADAM2ADAM metallopeptidase domain 20.021
ART4ADP-ribosyltransferase 4 (Dombrock blood group)0.021
PMP2peripheral myelin protein 20.021
HESX1HESX homeobox 10.021
ZNF81zinc finger protein 810.021
KIR3DL1killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 10.021
CTNNA3catenin (cadherin-associated protein), alpha 30.020
TM4SF20transmembrane 4 L six family member 200.020
ANXA10annexin A100.020
GNRHRgonadotropin-releasing hormone receptor0.020
ZNF157zinc finger protein 1570.020
MS4A5membrane-spanning 4-domains, subfamily A, member 50.020
IFNA6interferon, alpha 60.020
GABRA3gamma-aminobutyric acid (GABA) A receptor, alpha 30.020
PLSCR2phospholipid scramblase 20.020
PLAC1placenta-specific 10.020
LECT2leukocyte cell-derived chemotaxin 20.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tnftumor necrosis factor0.980
Map3k14mitogen-activated protein kinase kinase kinase 140.913
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.875
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.825
Nos2nitric oxide synthase 2, inducible0.728
Ighimmunoglobulin heavy chain complex0.698
Ltalymphotoxin A0.641
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.546
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.461
Traf2TNF receptor-associated factor 20.433
Traf6TNF receptor-associated factor 60.413
Ifnginterferon gamma0.401
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.369
Cd40lgCD40 ligand0.358
Ifna9interferon alpha 90.310
BtkBruton agammaglobulinemia tyrosine kinase0.306
Ccl2chemokine (C-C motif) ligand 20.287
Smr3asubmaxillary gland androgen regulated protein 3A0.118
Ifna2interferon alpha 20.115
Car1carbonic anhydrase 10.110
Siglecesialic acid binding Ig-like lectin E0.098
Csn1s1casein alpha s10.091
Sprr2ksmall proline-rich protein 2K0.088
Bcl3B-cell leukemia/lymphoma 30.086
Fut1fucosyltransferase 10.084
S1pr2sphingosine-1-phosphate receptor 20.084
Il10interleukin 100.083
Il6interleukin 60.076
Pax4paired box gene 40.074
Prkcdprotein kinase C, delta0.068
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.066
Ubdubiquitin D0.062
Itgb2lintegrin beta 2-like0.061
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.060
Zanzonadhesin0.058
Ifnabinterferon alpha B0.057
Csf1colony stimulating factor 1 (macrophage)0.052
Galr3galanin receptor 30.052
Hrh2histamine receptor H20.050
Cd19CD19 antigen0.050
Mx2myxovirus (influenza virus) resistance 20.049
Sykbspleen tyrosine kinase0.046
Bcl6B-cell leukemia/lymphoma 60.046
Gm12597predicted gene 125970.046
Tlr4toll-like receptor 40.042
Itln1intelectin 1 (galactofuranose binding)0.042
Cd40CD40 antigen0.041
Pla2g1bphospholipase A2, group IB, pancreas0.041
Sprr1bsmall proline-rich protein 1B0.040
Colqcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase0.040
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.040
Ltblymphotoxin B0.040
Hbb-bh1hemoglobin Z, beta-like embryonic chain0.040
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.039
Ifna5interferon alpha 50.039
Ifna12interferon alpha 120.038
G6pd2glucose-6-phosphate dehydrogenase 20.035
Ccl4chemokine (C-C motif) ligand 40.035
Aireautoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)0.035
Mc1rmelanocortin 1 receptor0.034
C5ar1complement component 5a receptor 10.034
Ptgs2prostaglandin-endoperoxide synthase 20.034
Csf3colony stimulating factor 3 (granulocyte)0.034
Map3k7mitogen-activated protein kinase kinase kinase 70.033
Fpr3formyl peptide receptor 30.032
Ifnb1interferon beta 1, fibroblast0.032
Crygdcrystallin, gamma D0.032
Socs1suppressor of cytokine signaling 10.031
AA516738expressed sequence AA5167380.031
Mocs1molybdenum cofactor synthesis 10.029
Gm12185predicted gene 121850.029
Hes2hairy and enhancer of split 2 (Drosophila)0.029
Tspo2translocator protein 20.028
Snai1snail homolog 1 (Drosophila)0.028
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.027
Gpr44G protein-coupled receptor 440.027
Sprr2ismall proline-rich protein 2I0.027
Bfsp1beaded filament structural protein 1, in lens-CP940.027
Ccr8chemokine (C-C motif) receptor 80.027
Gja10gap junction protein, alpha 100.026
Amelxamelogenin X chromosome0.026
Pramel7preferentially expressed antigen in melanoma like 70.026
Tnfaip3tumor necrosis factor, alpha-induced protein 30.026
1810030J14RikRIKEN cDNA 1810030J14 gene0.025
Tff3trefoil factor 3, intestinal0.025
MefvMediterranean fever0.024
Omt2boocyte maturation, beta0.024
Olfr49olfactory receptor 490.024
Tshbthyroid stimulating hormone, beta subunit0.024
Gp9glycoprotein 9 (platelet)0.024
Olfr159olfactory receptor 1590.023
Il3interleukin 30.023
2810449G22RikRIKEN cDNA 2810449G22 gene0.022
Plauplasminogen activator, urokinase0.022
Spp1secreted phosphoprotein 10.022
Ifna1interferon alpha 10.021
Slc22a12solute carrier family 22 (organic anion/cation transporter), member 120.021
Gastgastrin0.021
Ikbkginhibitor of kappaB kinase gamma0.021
Prl8a6prolactin family 8, subfamily a, member 60.020
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism