The network for 'plasma membrane organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

plasma membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.

NameDescriptionProbabilityFunc Analog Organism
GRB2growth factor receptor-bound protein 20.998
BCL2L1BCL2-like 10.995
ACTBactin, beta0.994
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.986
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.972
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.969
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.933
FASLGFas ligand (TNF superfamily, member 6)0.928
NCF1neutrophil cytosolic factor 10.920
FHL2four and a half LIM domains 20.912
C1QAcomplement component 1, q subcomponent, A chain0.908
DNM2dynamin 20.908
DNM1dynamin 10.884
FN1fibronectin 10.882
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.880
SNX9sorting nexin 90.874
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.854
PACSIN1protein kinase C and casein kinase substrate in neurons 10.837
FLNAfilamin A, alpha0.836
APCadenomatous polyposis coli0.830
KRT18keratin 180.796
FYNFYN oncogene related to SRC, FGR, YES0.793
RHOAras homolog gene family, member A0.790
PSEN1presenilin 10.784
S100BS100 calcium binding protein B0.772
SPTBspectrin, beta, erythrocytic0.765
S100A6S100 calcium binding protein A60.760
S100A9S100 calcium binding protein A90.757
HTThuntingtin0.756
EHD1EH-domain containing 10.733
STX12syntaxin 120.707
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.706
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.702
EZRezrin0.695
IQGAP1IQ motif containing GTPase activating protein 10.692
FLOT2flotillin 20.674
DAAM1dishevelled associated activator of morphogenesis 10.673
PLECplectin0.671
BCRbreakpoint cluster region0.655
APPamyloid beta (A4) precursor protein0.641
ITGB4integrin, beta 40.638
EXOC1exocyst complex component 10.634
ACTG1actin, gamma 10.630
SNAP23synaptosomal-associated protein, 23kDa0.613
APPL2adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 20.604
PXNpaxillin0.603
KRT8keratin 80.599
GGA3golgi-associated, gamma adaptin ear containing, ARF binding protein 30.561
EXOC7exocyst complex component 70.548
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.545
BCL2B-cell CLL/lymphoma 20.508
FYBFYN binding protein0.501
ENGendoglin0.479
NCF2neutrophil cytosolic factor 20.461
SH3GL3SH3-domain GRB2-like 30.450
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.437
CALM1calmodulin 1 (phosphorylase kinase, delta)0.432
NCF4neutrophil cytosolic factor 4, 40kDa0.424
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.424
PFN1profilin 10.422
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.419
COL1A1collagen, type I, alpha 10.418
SCHIP1schwannomin interacting protein 10.415
KRT6Bkeratin 6B0.411
COL3A1collagen, type III, alpha 10.410
MYH9myosin, heavy chain 9, non-muscle0.410
S100A8S100 calcium binding protein A80.409
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.408
CAPZA2capping protein (actin filament) muscle Z-line, alpha 20.404
EXOC8exocyst complex component 80.402
AKT1v-akt murine thymoma viral oncogene homolog 10.400
ZYXzyxin0.398
AP2B1adaptor-related protein complex 2, beta 1 subunit0.398
VAMP3vesicle-associated membrane protein 3 (cellubrevin)0.393
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.390
DSPdesmoplakin0.384
AP2A2adaptor-related protein complex 2, alpha 2 subunit0.384
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.375
FLOT1flotillin 10.369
BCL2L11BCL2-like 11 (apoptosis facilitator)0.367
JUPjunction plakoglobin0.364
EPS8epidermal growth factor receptor pathway substrate 80.345
CTTNcortactin0.343
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.334
COL4A1collagen, type IV, alpha 10.334
WASLWiskott-Aldrich syndrome-like0.333
STX4syntaxin 40.331
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.326
FNBP1formin binding protein 10.318
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.316
INADLInaD-like (Drosophila)0.312
SPTA1spectrin, alpha, erythrocytic 1 (elliptocytosis 2)0.312
PSEN2presenilin 2 (Alzheimer disease 4)0.305
CFL1cofilin 1 (non-muscle)0.304
LMAN1lectin, mannose-binding, 10.300
S100A1S100 calcium binding protein A10.297
C1QCcomplement component 1, q subcomponent, C chain0.295
HCKhemopoietic cell kinase0.294
DSG2desmoglein 20.287
MARK3MAP/microtubule affinity-regulating kinase 30.287
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
gpb-1Protein GPB-10.078
goa-1Protein GOA-10.063
lin-36Protein LIN-360.042
egl-44Protein EGL-440.035
ina-1Protein INA-10.032
vav-1Protein VAV-10.024
hmr-1Protein HMR-10.024
sur-2Protein SUR-20.023
sma-1Protein SMA-10.022
ret-1Protein RET-10.021
unc-115Protein UNC-1150.020
scd-1Protein SCD-10.020
tag-343Protein TAG-3430.020
unc-68Protein UNC-680.019
miz-1Protein MIZ-10.017
rab-1Protein RAB-10.016
trcs-2Protein TRCS-20.015
ykt-6Protein YKT-60.014
unc-43Protein UNC-430.014
helq-1Protein HELQ-10.014
pat-3Protein PAT-30.014
let-607Protein LET-6070.014
kin-4Protein KIN-40.014
T19A6.1Protein T19A6.10.012
csnk-1Protein CSNK-10.012
pxf-1Protein PXF-10.012
sem-5Protein SEM-50.012
K10C3.4Protein K10C3.40.012
CELE_F53C11.5Protein F53C11.50.012
eat-20Protein EAT-200.012
dnj-27Protein DNJ-270.012
rho-1Protein RHO-10.011
F41H10.4Protein F41H10.40.011
B0395.3Protein B0395.30.011
thoc-2Protein THOC-20.011
cpt-1Protein CPT-10.011
unc-83Protein UNC-830.011
ehs-1Protein EHS-10.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
anxa2aannexin A2a0.027
itgb1b.2integrin, beta 1b.20.021
cdh2cadherin 2, neuronal0.011
anxa1aannexin A1a0.011
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rab11Rab-protein 110.913
crbcrumbs0.594
Fas2Fasciclin 20.566
didumdilute class unconventional myosin0.545
Pi3K92ECG4141 gene product from transcript CG4141-RB0.210
mysmyospheroid0.161
cpacapping protein alpha0.160
WASpCG1520 gene product from transcript CG1520-RA0.156
sqhspaghetti squash0.141
Arc-p34CG10954 gene product from transcript CG10954-RA0.127
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.125
cpbcapping protein beta0.105
sec5CG8843 gene product from transcript CG8843-RA0.095
lqfRliquid facets-Related0.095
l(2)gllethal (2) giant larvae0.089
stcksteamer duck0.086
poepurity of essence0.084
Rho1CG8416 gene product from transcript CG8416-RB0.080
shotshort stop0.077
CG3033CG3033 gene product from transcript CG3033-RA0.071
Hip14Huntingtin-interacting protein 140.071
sggshaggy0.070
Nrx-IVNeurexin IV0.068
bazbazooka0.067
zipzipper0.065
Cdc42CG12530 gene product from transcript CG12530-RA0.065
sec6CG5341 gene product from transcript CG5341-RA0.062
eglegalitarian0.062
Pk61CProtein kinase 61C0.059
CaMKIICalcium/calmodulin-dependent protein kinase II0.057
exo84CG6095 gene product from transcript CG6095-RA0.056
CG13089CG13089 gene product from transcript CG13089-RA0.056
frcfringe connection0.054
Pink1PTEN-induced putative kinase 10.053
GugGrunge0.049
MoeMoesin0.048
Snap25Synapse protein 250.047
eIF4Geukaryotic translation initiation factor 4G0.046
ttvtout-velu0.046
inscinscuteable0.045
c11.1CG12132 gene product from transcript CG12132-RA0.044
fryfurry0.043
RhebCG1081 gene product from transcript CG1081-RA0.041
kstkarst0.041
diadiaphanous0.041
mavmaverick0.040
alpha-Specalpha Spectrin0.038
eghegghead0.036
Sop2Suppressor of profilin 20.035
KhcKinesin heavy chain0.035
l(2)k14710lethal (2) k147100.034
icsicarus0.034
CG8004CG8004 gene product from transcript CG8004-RA0.034
elavembryonic lethal abnormal vision0.033
staistathmin0.033
gekgenghis khan0.033
certceramide transfer protein0.032
cindrCIN85 and CD2AP orthologue0.032
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.032
auxauxillin0.031
CG10222CG10222 gene product from transcript CG10222-RA0.031
neuroliginCG13772 gene product from transcript CG13772-RA0.031
enaenabled0.031
giggigas0.030
Syx1ASyntaxin 1A0.030
beta4GalNAcTACG8536 gene product from transcript CG8536-RA0.030
cdmcadmus0.030
neurneuralized0.030
witwishful thinking0.030
PatjCG12021 gene product from transcript CG12021-RC0.029
Rme-8Receptor mediated endocytosis 80.029
Tsp3ATetraspanin 3A0.029
CragCalmodulin-binding protein related to a Rab3 GDP/GTP exchange protein0.029
CG7806CG7806 gene product from transcript CG7806-RA0.029
Vps16AVacuolar protein sorting 16A0.029
Smg1CG32743 gene product from transcript CG32743-RA0.028
rtGEFrho-type guanine exchange factor0.028
CG11665CG11665 gene product from transcript CG11665-RA0.028
DadDaughters against dpp0.028
tkvthickveins0.028
sec8CG2095 gene product from transcript CG2095-RA0.027
uspultraspiracle0.027
nudECG8104 gene product from transcript CG8104-RB0.026
Arf51FADP ribosylation factor 51F0.026
rheaCG6831 gene product from transcript CG6831-RA0.026
ChcClathrin heavy chain0.026
wunwunen0.026
Orc6Origin recognition complex subunit 60.026
vibvibrator0.025
unc-104CG8566 gene product from transcript CG8566-RB0.025
CG12945CG12945 gene product from transcript CG12945-RB0.024
Plc21CPhospholipase C at 21C0.024
trptransient receptor potential0.024
babobaboon0.024
Rac1CG2248 gene product from transcript CG2248-RA0.024
scuscully0.023
LaspCG3849 gene product from transcript CG3849-RB0.023
par-1CG8201 gene product from transcript CG8201-RA0.023
Pp2A-29BProtein phosphatase 2A at 29B0.023
Ank2Ankyrin 20.023
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Appamyloid beta (A4) precursor protein0.919
Anxa2annexin A20.798
Prnpprion protein0.763
S100a6S100 calcium binding protein A6 (calcyclin)0.718
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.657
Rnf208ring finger protein 2080.655
Lama5laminin, alpha 50.650
Slc34a1solute carrier family 34 (sodium phosphate), member 10.628
Nf2neurofibromatosis 20.621
Ctnna1catenin (cadherin associated protein), alpha 10.566
Spnb2spectrin beta 20.520
Lcklymphocyte protein tyrosine kinase0.515
S100a4S100 calcium binding protein A40.486
Anxa1annexin A10.461
Ptrfpolymerase I and transcript release factor0.444
Lamc1laminin, gamma 10.428
Dlg4discs, large homolog 4 (Drosophila)0.423
Ccr1chemokine (C-C motif) receptor 10.399
Nrxn1neurexin I0.392
Cd44CD44 antigen0.389
S100a13S100 calcium binding protein A130.389
Capn2calpain 20.387
S100a8S100 calcium binding protein A8 (calgranulin A)0.387
Add1adducin 1 (alpha)0.384
Gsk3bglycogen synthase kinase 3 beta0.384
Dlg1discs, large homolog 1 (Drosophila)0.374
Cttncortactin0.372
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.367
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.359
Retret proto-oncogene0.356
Ccr2chemokine (C-C motif) receptor 20.353
Ctnnd1catenin (cadherin associated protein), delta 10.337
Ptprcprotein tyrosine phosphatase, receptor type, C0.331
Ash1lash1 (absent, small, or homeotic)-like (Drosophila)0.329
S100a9S100 calcium binding protein A9 (calgranulin B)0.329
Dmddystrophin, muscular dystrophy0.319
Lmnalamin A0.297
Tsc1tuberous sclerosis 10.275
Apcadenomatosis polyposis coli0.273
Spna2spectrin alpha 20.267
Egln1EGL nine homolog 1 (C. elegans)0.267
Gja1gap junction protein, alpha 10.265
Bcl2B-cell leukemia/lymphoma 20.261
L1camL1 cell adhesion molecule0.251
Fliiflightless I homolog (Drosophila)0.251
Fjx1four jointed box 1 (Drosophila)0.247
Grap2GRB2-related adaptor protein 20.247
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.244
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.241
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.239
Cdh5cadherin 50.238
Pdcd6ipprogrammed cell death 6 interacting protein0.231
Fechferrochelatase0.224
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.217
Itgb1integrin beta 1 (fibronectin receptor beta)0.216
Drd2dopamine receptor D20.212
Fgfr1fibroblast growth factor receptor 10.208
Plcb1phospholipase C, beta 10.204
Msnmoesin0.203
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.201
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.198
Nf1neurofibromatosis 10.196
Nos1nitric oxide synthase 1, neuronal0.191
Rac1RAS-related C3 botulinum substrate 10.189
S100a11S100 calcium binding protein A11 (calgizzarin)0.188
Maptmicrotubule-associated protein tau0.186
St8sia5ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 50.185
Fgfr2fibroblast growth factor receptor 20.184
Capzbcapping protein (actin filament) muscle Z-line, beta0.180
Gabrdgamma-aminobutyric acid (GABA) A receptor, subunit delta0.176
Syt6synaptotagmin VI0.172
Fgfbp1fibroblast growth factor binding protein 10.172
Prkczprotein kinase C, zeta0.169
Pip5k1cphosphatidylinositol-4-phosphate 5-kinase, type 1 gamma0.168
S100a10S100 calcium binding protein A10 (calpactin)0.168
Rps3ribosomal protein S30.167
Slc4a1solute carrier family 4 (anion exchanger), member 10.166
Vapavesicle-associated membrane protein, associated protein A0.165
Kif3akinesin family member 3A0.163
Nrxn3neurexin III0.163
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.162
Wnk2WNK lysine deficient protein kinase 20.158
IhhIndian hedgehog0.158
Largelike-glycosyltransferase0.158
Tpm4tropomyosin 40.151
Sema3bsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B0.151
Iqgap1IQ motif containing GTPase activating protein 10.149
Myh14myosin, heavy polypeptide 140.148
Cnr1cannabinoid receptor 1 (brain)0.147
Dag1dystroglycan 10.146
Ctnnb1catenin (cadherin associated protein), beta 10.145
Dync1h1dynein cytoplasmic 1 heavy chain 10.143
Capza2capping protein (actin filament) muscle Z-line, alpha 20.142
Glg1golgi apparatus protein 10.141
Ptprnprotein tyrosine phosphatase, receptor type, N0.140
Sh3gl2SH3-domain GRB2-like 20.140
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.139
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.138
Efna1ephrin A10.137
Rhoaras homolog gene family, member A0.137
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Serpinb6aserine (or cysteine) peptidase inhibitor, clade B, member 6a0.047
S100a8S100 calcium binding protein A80.047
Anxa2annexin A20.046
Capn2calpain 20.046
AhnakAHNAK nucleoprotein0.034
Pfn1profilin 10.032
S100a11S100 calcium binding protein A11 (calizzarin)0.031
Vimvimentin0.031
Nrxn1neurexin 10.030
Anxa5annexin A50.028
Myadmmyeloid-associated differentiation marker0.028
Nlgn3neuroligin 30.027
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.026
Anxa1annexin A10.026
FauFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed0.024
Cd151CD151 molecule (Raph blood group)0.020
Elnelastin0.020
S100a6S100 calcium binding protein A60.020
S100a10S100 calcium binding protein A100.020
Stx1asyntaxin 1A (brain)0.019
Anxa4annexin A40.017
Itgb1integrin, beta 10.017
Wdr1WD repeat domain 10.016
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.016
Hk1hexokinase 10.016
Atp6v0a1ATPase, H+ transporting, lysosomal V0 subunit A10.016
Cttncortactin0.015
Syngr2synaptogyrin 20.014
Arhgap1Rho GTPase activating protein 10.014
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.014
Tecrtrans-2,3-enoyl-CoA reductase0.013
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.013
Amphamphiphysin0.013
LOC683626similar to limb-bud and heart0.012
Mtpnmyotrophin0.012
Dnm1dynamin 10.012
Vamp3vesicle-associated membrane protein 30.012
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.012
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.011
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.011
Dctn1dynactin 10.011
Rab7aRAB7A, member RAS oncogene family0.011
Syn1synapsin I0.011
Sdcbpsyndecan binding protein0.011
Nfe2l2nuclear factor, erythroid derived 2, like 20.011
Rhoaras homolog gene family, member A0.011
Stxbp1syntaxin binding protein 10.011
Exoc7exocyst complex component 70.011
S100a4S100 calcium-binding protein A40.010
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.010
Map6microtubule-associated protein 60.010
Cd5Cd5 molecule0.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
APL3Apl3p0.148
MYO5Myo5p0.125
SNC2Snc2p0.119
SEC1Sec1p0.109
SSO1Sso1p0.105
APS2Aps2p0.092
YTA6Yta6p0.086
ALG8Alg8p0.070
YPT1Ypt1p0.067
ARC40Arc40p0.067
VPS1Vps1p0.066
CNB1Cnb1p0.060
PMP3Pmp3p0.059
GCS1Gcs1p0.059
SSO2Sso2p0.056
SHE3She3p0.055
UGO1Ugo1p0.049
SEC21Sec21p0.047
APE3Ape3p0.047
GLO3Glo3p0.045
PSD2Psd2p0.045
YPT31Ypt31p0.043
EFR3Efr3p0.041
KAP104Kap104p0.039
YKT6Ykt6p0.036
SYS1Sys1p0.036
KES1Kes1p0.035
ARP2Arp2p0.034
ARL3Arl3p0.033
VPS17Vps17p0.032
YPT10Ypt10p0.032
PNS1Pns1p0.031
NGR1Ngr1p0.031
YMR086Whypothetical protein0.030
EHT1Eht1p0.030
PLB2Plb2p0.029
SAR1Sar1p0.028
CSR1Csr1p0.028
TLG1Tlg1p0.028
APM1Apm1p0.026
BSP1Bsp1p0.026
RAS2Ras2p0.024
KTR6Ktr6p0.023
CRN1Crn1p0.023
LSP1Lsp1p0.023
ARC35Arc35p0.023
INP52Inp52p0.023
VPS13Vps13p0.022
ENT3Ent3p0.022
ERD2Erd2p0.022
YPT6Ypt6p0.021
TCP1Tcp1p0.021
SLA2Sla2p0.021
BTN2Btn2p0.021
MDN1Mdn1p0.020
MDM32Mdm32p0.020
YKR051Whypothetical protein0.020
VPS38Vps38p0.020
ALO1Alo1p0.020
PEP1Pep1p0.020
APS1Aps1p0.020
VPS28Vps28p0.019
SNC1Snc1p0.019
CCC1Ccc1p0.019
GSP2Gsp2p0.019
APL2Apl2p0.018
HOC1Hoc1p0.018
VTI1Vti1p0.018
NMT1Nmt1p0.018
YIR035Chypothetical protein0.018
PEP4Pep4p0.018
PER1Per1p0.017
YLR264C-Ahypothetical protein0.017
SHE9She9p0.017
SRD1Srd1p0.017
YNL108Chypothetical protein0.017
ABP140Abp140p0.017
YPC1Ypc1p0.017
AAC3Aac3p0.017
YKL077Whypothetical protein0.017
YLR162Whypothetical protein0.017
YOL014Whypothetical protein0.016
GIP4Gip4p0.016
APL1Apl1p0.016
SRO7Sro7p0.016
YIP1Yip1p0.016
MIG1Mig1p0.016
MSO1Mso1p0.016
CPD1Cpd1p0.016
YIF1Yif1p0.016
YJR116Whypothetical protein0.016
RSN1Rsn1p0.016
ACC1Acc1p0.015
YCK1Yck1p0.015
AKL1Akl1p0.015
CWP2Cwp2p0.015
ARF2Arf2p0.015
LAT1Lat1p0.015
ERD1Erd1p0.015
PMP2Pmp2p0.015