The network for 'pattern specification involved in kidney development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pattern specification involved in kidney development

Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.

NameDescriptionProbabilityFunc Analog Organism
BMPR1Abone morphogenetic protein receptor, type IA1.000
FSTL1follistatin-like 11.000
NKX2-1NK2 homeobox 11.000
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.993
BBS1Bardet-Biedl syndrome 10.989
ZFYVE9zinc finger, FYVE domain containing 90.977
NOGnoggin0.956
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.921
BMPR1Bbone morphogenetic protein receptor, type IB0.678
WNT7Awingless-type MMTV integration site family, member 7A0.520
BMP4bone morphogenetic protein 40.505
BBS4Bardet-Biedl syndrome 40.500
IRX5iroquois homeobox 50.488
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.376
TGFB1transforming growth factor, beta 10.345
BMP2bone morphogenetic protein 20.341
BBS2Bardet-Biedl syndrome 20.332
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila)0.261
FGF4fibroblast growth factor 40.194
DLL3delta-like 3 (Drosophila)0.192
LHX1LIM homeobox 10.169
HNF1BHNF1 homeobox B0.140
WT1Wilms tumor 10.125
HOXA11homeobox A110.123
PAX7paired box 70.107
SIM2single-minded homolog 2 (Drosophila)0.106
HES2hairy and enhancer of split 2 (Drosophila)0.106
FSTfollistatin0.090
OLIG2oligodendrocyte lineage transcription factor 20.089
CDH16cadherin 16, KSP-cadherin0.087
C5orf38chromosome 5 open reading frame 380.086
PYYpeptide YY0.073
LBX1ladybird homeobox 10.071
COL2A1collagen, type II, alpha 10.070
OTOP2otopetrin 20.070
PAX8paired box 80.066
EDN1endothelin 10.065
GLI3GLI family zinc finger 30.057
GPR6G protein-coupled receptor 60.057
EFNA2ephrin-A20.054
IRX1iroquois homeobox 10.054
OVOL1ovo-like 1(Drosophila)0.052
FOXE1forkhead box E1 (thyroid transcription factor 2)0.051
HNF1AHNF1 homeobox A0.051
FZD8frizzled homolog 8 (Drosophila)0.043
CRHR1corticotropin releasing hormone receptor 10.040
BBS7Bardet-Biedl syndrome 70.040
WNT4wingless-type MMTV integration site family, member 40.038
TGFB2transforming growth factor, beta 20.038
PAX3paired box 30.038
FGF8fibroblast growth factor 8 (androgen-induced)0.037
FGF18fibroblast growth factor 180.035
POU3F3POU class 3 homeobox 30.034
HOXC12homeobox C120.034
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.033
NKX6-2NK6 homeobox 20.032
KLHL35kelch-like 35 (Drosophila)0.032
WNT1wingless-type MMTV integration site family, member 10.031
SLIT2slit homolog 2 (Drosophila)0.031
BHLHE23basic helix-loop-helix family, member e230.030
ONECUT2one cut homeobox 20.030
MYL3myosin, light chain 3, alkali; ventricular, skeletal, slow0.030
SOSTDC1sclerostin domain containing 10.028
ALDOBaldolase B, fructose-bisphosphate0.027
BMP6bone morphogenetic protein 60.027
GGNgametogenetin0.027
CDKN2Bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.026
HOXD13homeobox D130.026
LMX1BLIM homeobox transcription factor 1, beta0.026
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.026
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.025
HOXB8homeobox B80.025
CRLF1cytokine receptor-like factor 10.024
GSX2GS homeobox 20.024
BMP7bone morphogenetic protein 70.024
FOXC1forkhead box C10.024
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.023
CHRNA4cholinergic receptor, nicotinic, alpha 40.023
ATP4BATPase, H+/K+ exchanging, beta polypeptide0.023
HOXD11homeobox D110.022
HOXC5homeobox C50.022
ZNF503zinc finger protein 5030.022
INHBBinhibin, beta B0.022
SOX18SRY (sex determining region Y)-box 180.021
IRX4iroquois homeobox 40.021
F3coagulation factor III (thromboplastin, tissue factor)0.021
ALX4ALX homeobox 40.021
COL13A1collagen, type XIII, alpha 10.020
HOXD9homeobox D90.019
LHX2LIM homeobox 20.019
EPHA8EPH receptor A80.019
SUMF2sulfatase modifying factor 20.019
RTN4RL2reticulon 4 receptor-like 20.018
IRX2iroquois homeobox 20.018
FAM163Bfamily with sequence similarity 163, member B0.018
GBX2gastrulation brain homeobox 20.018
EMX1empty spiracles homeobox 10.018
EN2engrailed homeobox 20.018
IL11interleukin 110.018
TBX1T-box 10.017
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Otx2orthodenticle homolog 2 (Drosophila)0.994
Pax2paired box gene 20.994
Emx2empty spiracles homolog 2 (Drosophila)0.987
Shhsonic hedgehog0.979
Lhx1LIM homeobox protein 10.942
Foxc1forkhead box C10.935
Eya1eyes absent 1 homolog (Drosophila)0.786
Otx1orthodenticle homolog 1 (Drosophila)0.703
Hmx3H6 homeobox 30.669
Tbx1T-box 10.615
Dlx5distal-less homeobox 50.501
Lmx1aLIM homeobox transcription factor 1 alpha0.475
Hmx1H6 homeobox 10.469
Fgfr2fibroblast growth factor receptor 20.464
Fgf8fibroblast growth factor 80.404
Msx1homeobox, msh-like 10.393
Emx1empty spiracles homolog 1 (Drosophila)0.382
Nognoggin0.306
Hoxd3homeobox D30.283
Foxg1forkhead box G10.271
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.262
Hand1heart and neural crest derivatives expressed transcript 10.260
Pax8paired box gene 80.256
Gli3GLI-Kruppel family member GLI30.231
Nkx2-1NK2 homeobox 10.218
Lhx9LIM homeobox protein 90.204
Pax3paired box gene 30.200
Foxc2forkhead box C20.195
En1engrailed 10.174
Gscgoosecoid homeobox0.172
Hes5hairy and enhancer of split 5 (Drosophila)0.166
Vax1ventral anterior homeobox containing gene 10.151
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.148
Rargretinoic acid receptor, gamma0.146
Bmp4bone morphogenetic protein 40.143
Hoxd11homeobox D110.128
Tcfap2atranscription factor AP-2, alpha0.124
Foxa2forkhead box A20.118
Pax6paired box gene 60.115
Hoxa2homeobox A20.114
Wnt1wingless-related MMTV integration site 10.112
Hand2heart and neural crest derivatives expressed transcript 20.108
Irx5Iroquois related homeobox 5 (Drosophila)0.105
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.104
Hoxa1homeobox A10.103
Wnt9bwingless-type MMTV integration site 9B0.101
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.085
Pax9paired box gene 90.085
Gbx2gastrulation brain homeobox 20.079
Lmx1bLIM homeobox transcription factor 1 beta0.071
Sox2SRY-box containing gene 20.071
Six2sine oculis-related homeobox 2 homolog (Drosophila)0.062
Pitx2paired-like homeodomain transcription factor 20.059
Irx1Iroquois related homeobox 1 (Drosophila)0.054
Rarbretinoic acid receptor, beta0.052
Tlx3T-cell leukemia, homeobox 30.047
Neurog1neurogenin 10.047
Ascl1achaete-scute complex homolog 1 (Drosophila)0.045
Irx2Iroquois related homeobox 2 (Drosophila)0.042
Nr5a1nuclear receptor subfamily 5, group A, member 10.042
Bnc1basonuclin 10.038
UncxUNC homeobox0.038
Rararetinoic acid receptor, alpha0.037
Hoxa11homeobox A110.037
Wnt3awingless-related MMTV integration site 3A0.036
Foxi1forkhead box I10.036
Tbrachyury0.035
Pdx1pancreatic and duodenal homeobox 10.034
Lhx5LIM homeobox protein 50.033
Foxa1forkhead box A10.033
FevFEV (ETS oncogene family)0.030
Hoxb1homeobox B10.029
Gdnfglial cell line derived neurotrophic factor0.029
Bmp7bone morphogenetic protein 70.028
Pou4f2POU domain, class 4, transcription factor 20.028
Irx3Iroquois related homeobox 3 (Drosophila)0.027
Smosmoothened homolog (Drosophila)0.027
Hoxb2homeobox B20.027
Hoxd9homeobox D90.026
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.025
Prrx1paired related homeobox 10.023
Hoxa3homeobox A30.021
Zfp503zinc finger protein 5030.021
Pbx1pre B-cell leukemia transcription factor 10.020
Efnb2ephrin B20.020
Msx2homeobox, msh-like 20.020
Lhx3LIM homeobox protein 30.020
Wt1Wilms tumor 1 homolog0.019
Tcfap2ctranscription factor AP-2, gamma0.018
Hoxd1homeobox D10.018
Fgf15fibroblast growth factor 150.018
Cdx1caudal type homeobox 10.018
Chd7chromodomain helicase DNA binding protein 70.017
Foxb1forkhead box B10.017
Hes3hairy and enhancer of split 3 (Drosophila)0.016
Pitx3paired-like homeodomain transcription factor 30.016
Nkx6-1NK6 homeobox 10.016
Hoxb3homeobox B30.015
Dlx2distal-less homeobox 20.015
Gas1growth arrest specific 10.015
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism