The network for 'regulation of male gonad development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of male gonad development

Any process that modulates the frequency, rate or extent of male gonad development.

NameDescriptionProbabilityFunc Analog Organism
POU3F2POU class 3 homeobox 20.999
PAX3paired box 30.998
HIPK2homeodomain interacting protein kinase 20.942
PROX1prospero homeobox 10.925
MEOX2mesenchyme homeobox 20.801
SMAD7SMAD family member 70.717
FGF18fibroblast growth factor 180.496
DVL3dishevelled, dsh homolog 3 (Drosophila)0.491
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.466
HNF4Ahepatocyte nuclear factor 4, alpha0.439
WNT1wingless-type MMTV integration site family, member 10.347
SOX21SRY (sex determining region Y)-box 210.294
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.267
MARCKSL1MARCKS-like 10.256
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.229
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.212
FOXG1forkhead box G10.205
SALL2sal-like 2 (Drosophila)0.184
OLIG2oligodendrocyte lineage transcription factor 20.177
PAX6paired box 60.143
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.140
WIF1WNT inhibitory factor 10.128
C1QL1complement component 1, q subcomponent-like 10.127
SOX1SRY (sex determining region Y)-box 10.127
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.125
EP300E1A binding protein p3000.125
SFRP1secreted frizzled-related protein 10.122
GATA4GATA binding protein 40.119
AQP5aquaporin 50.116
ADRA1Dadrenergic, alpha-1D-, receptor0.111
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.110
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.108
POU3F1POU class 3 homeobox 10.108
SOX11SRY (sex determining region Y)-box 110.105
FGF4fibroblast growth factor 40.103
LBX1ladybird homeobox 10.102
TBX2T-box 20.098
HOXD13homeobox D130.087
NR0B1nuclear receptor subfamily 0, group B, member 10.086
POU3F3POU class 3 homeobox 30.085
MMP11matrix metallopeptidase 11 (stromelysin 3)0.085
FGF8fibroblast growth factor 8 (androgen-induced)0.084
COL2A1collagen, type II, alpha 10.083
ELK1ELK1, member of ETS oncogene family0.082
FOXD3forkhead box D30.082
WNT6wingless-type MMTV integration site family, member 60.082
BMP7bone morphogenetic protein 70.081
HES2hairy and enhancer of split 2 (Drosophila)0.080
CXXC5CXXC finger protein 50.078
SHHsonic hedgehog0.075
SOX5SRY (sex determining region Y)-box 50.075
TAOK1TAO kinase 10.071
OTPorthopedia homeobox0.069
INHBBinhibin, beta B0.068
FOXE1forkhead box E1 (thyroid transcription factor 2)0.067
HOXD9homeobox D90.064
GDNFglial cell derived neurotrophic factor0.062
WNT3wingless-type MMTV integration site family, member 30.059
DVL1dishevelled, dsh homolog 1 (Drosophila)0.058
MSX1msh homeobox 10.058
GJC2gap junction protein, gamma 2, 47kDa0.058
SMAD5SMAD family member 50.057
HOXD3homeobox D30.057
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.056
TBX1T-box 10.056
HOXB13homeobox B130.055
HOXD1homeobox D10.054
CDX1caudal type homeobox 10.054
PAX7paired box 70.054
SOX9SRY (sex determining region Y)-box 90.054
WT1Wilms tumor 10.054
SALL3sal-like 3 (Drosophila)0.053
SIX2SIX homeobox 20.053
DLX4distal-less homeobox 40.051
SMURF2SMAD specific E3 ubiquitin protein ligase 20.051
SIM2single-minded homolog 2 (Drosophila)0.050
SMAD4SMAD family member 40.050
ENTPD2ectonucleoside triphosphate diphosphohydrolase 20.050
GUCA2Aguanylate cyclase activator 2A (guanylin)0.049
PAX2paired box 20.048
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.046
TTYH1tweety homolog 1 (Drosophila)0.046
MMP16matrix metallopeptidase 16 (membrane-inserted)0.046
KCNK12potassium channel, subfamily K, member 120.046
HES5hairy and enhancer of split 5 (Drosophila)0.045
HIC1hypermethylated in cancer 10.045
GRIN2Dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.045
GBX2gastrulation brain homeobox 20.044
ZIC3Zic family member 3 (odd-paired homolog, Drosophila)0.044
MAGmyelin associated glycoprotein0.043
SFRP5secreted frizzled-related protein 50.043
GRIK3glutamate receptor, ionotropic, kainate 30.043
HCRTR1hypocretin (orexin) receptor 10.043
IHHIndian hedgehog0.043
BMP8Abone morphogenetic protein 8a0.043
FSCN2fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)0.043
WNT10Awingless-type MMTV integration site family, member 10A0.042
FGF3fibroblast growth factor 30.042
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gata4GATA binding protein 40.966
Kiss1KiSS-1 metastasis-suppressor0.832
Ptpn11protein tyrosine phosphatase, non-receptor type 110.495
Lhx9LIM homeobox protein 90.358
Amhr2anti-Mullerian hormone type 2 receptor0.330
Gata6GATA binding protein 60.263
Rxraretinoid X receptor alpha0.199
Esr1estrogen receptor 1 (alpha)0.143
Nab2Ngfi-A binding protein 20.132
Nr0b1nuclear receptor subfamily 0, group B, member 10.111
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.105
Pitx1paired-like homeodomain transcription factor 10.081
Gnrhrgonadotropin releasing hormone receptor0.079
Hand2heart and neural crest derivatives expressed transcript 20.069
Arandrogen receptor0.067
Fgf8fibroblast growth factor 80.066
Fshrfollicle stimulating hormone receptor0.065
Nr5a1nuclear receptor subfamily 5, group A, member 10.065
Fgfr2fibroblast growth factor receptor 20.064
Irs2insulin receptor substrate 20.059
Osr1odd-skipped related 1 (Drosophila)0.058
Plxna4plexin A40.053
Lhcgrluteinizing hormone/choriogonadotropin receptor0.052
Lhx1LIM homeobox protein 10.047
Emx2empty spiracles homolog 2 (Drosophila)0.044
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.043
Pitx2paired-like homeodomain transcription factor 20.039
Kiss1rKISS1 receptor0.038
Ntf3neurotrophin 30.036
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.035
Gnrh1gonadotropin releasing hormone 10.033
Inhainhibin alpha0.032
Gata5GATA binding protein 50.028
Hey2hairy/enhancer-of-split related with YRPW motif 20.027
Nab1Ngfi-A binding protein 10.024
Egr1early growth response 10.023
Wnt6wingless-related MMTV integration site 60.022
Dhhdesert hedgehog0.022
Utf1undifferentiated embryonic cell transcription factor 10.021
Pou5f1POU domain, class 5, transcription factor 10.021
Nhlh2nescient helix loop helix 20.020
Shhsonic hedgehog0.019
Pax2paired box gene 20.019
Foxc1forkhead box C10.019
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.019
JunbJun-B oncogene0.018
Egr2early growth response 20.018
Lhx3LIM homeobox protein 30.018
Ednraendothelin receptor type A0.017
Bmp4bone morphogenetic protein 40.016
FosFBJ osteosarcoma oncogene0.016
Jag1jagged 10.016
Acvr1activin A receptor, type 10.016
Tgfb2transforming growth factor, beta 20.016
Tbx1T-box 10.015
Dlg4discs, large homolog 4 (Drosophila)0.014
Nr4a1nuclear receptor subfamily 4, group A, member 10.014
Vegfavascular endothelial growth factor A0.013
Bmpr1abone morphogenetic protein receptor, type 1A0.013
Onecut3one cut domain, family member 30.013
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.012
Wt1Wilms tumor 1 homolog0.012
Nkx6-1NK6 homeobox 10.012
Rararetinoic acid receptor, alpha0.012
Prox1prospero-related homeobox 10.011
Sall4sal-like 4 (Drosophila)0.011
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.011
Ror1receptor tyrosine kinase-like orphan receptor 10.010
Mark4MAP/microtubule affinity-regulating kinase 40.010
Lama5laminin, alpha 50.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism