The network for 'positive regulation of mononuclear cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of mononuclear cell proliferation

Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.

NameDescriptionProbabilityFunc Analog Organism
GRB2growth factor receptor-bound protein 20.999
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.985
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.954
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.951
FGFR2fibroblast growth factor receptor 20.943
BCL2B-cell CLL/lymphoma 20.883
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.864
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.829
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.798
CD80CD80 molecule0.766
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.744
IL1R1interleukin 1 receptor, type I0.733
PTPN1protein tyrosine phosphatase, non-receptor type 10.692
BTN3A3butyrophilin, subfamily 3, member A30.648
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.634
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.631
SOCS3suppressor of cytokine signaling 30.617
IRAK1interleukin-1 receptor-associated kinase 10.595
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.545
CTLA4cytotoxic T-lymphocyte-associated protein 40.506
CCR5chemokine (C-C motif) receptor 50.499
LCKlymphocyte-specific protein tyrosine kinase0.496
TICAM2toll-like receptor adaptor molecule 20.485
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.481
CD86CD86 molecule0.479
LST1leukocyte specific transcript 10.476
ICAM1intercellular adhesion molecule 10.474
CCL4chemokine (C-C motif) ligand 40.446
BCL2L1BCL2-like 10.428
IL2RBinterleukin 2 receptor, beta0.418
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.400
LATlinker for activation of T cells0.398
CCR7chemokine (C-C motif) receptor 70.391
CXCL9chemokine (C-X-C motif) ligand 90.382
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.364
IL1Binterleukin 1, beta0.359
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.345
IL8interleukin 80.303
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.298
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.298
CCL2chemokine (C-C motif) ligand 20.295
PTPN6protein tyrosine phosphatase, non-receptor type 60.295
SYKspleen tyrosine kinase0.284
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.276
IL6interleukin 6 (interferon, beta 2)0.263
CCL22chemokine (C-C motif) ligand 220.261
BTN3A2butyrophilin, subfamily 3, member A20.257
CCL13chemokine (C-C motif) ligand 130.255
JAK1Janus kinase 10.247
BCL10B-cell CLL/lymphoma 100.241
IL2RGinterleukin 2 receptor, gamma0.241
TRAF3IP3TRAF3 interacting protein 30.237
TRAF6TNF receptor-associated factor 60.232
CCL8chemokine (C-C motif) ligand 80.221
CXCL2chemokine (C-X-C motif) ligand 20.213
RUNX1runt-related transcription factor 10.210
PLCG1phospholipase C, gamma 10.209
IRF4interferon regulatory factor 40.200
SLASrc-like-adaptor0.198
BCL2L11BCL2-like 11 (apoptosis facilitator)0.197
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.191
FGF1fibroblast growth factor 1 (acidic)0.182
MYD88myeloid differentiation primary response gene (88)0.178
GAS7growth arrest-specific 70.177
IRAK2interleukin-1 receptor-associated kinase 20.177
STAT4signal transducer and activator of transcription 40.172
INSRinsulin receptor0.170
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.167
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.164
FGFR1fibroblast growth factor receptor 10.159
IL10interleukin 100.158
HDAC9histone deacetylase 90.157
CASP10caspase 10, apoptosis-related cysteine peptidase0.152
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.150
BTKBruton agammaglobulinemia tyrosine kinase0.148
GRB10growth factor receptor-bound protein 100.148
BCAR1breast cancer anti-estrogen resistance 10.143
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.139
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.139
IL4Rinterleukin 4 receptor0.138
NLRP3NLR family, pyrin domain containing 30.137
SIGLEC7sialic acid binding Ig-like lectin 70.132
PILRApaired immunoglobin-like type 2 receptor alpha0.131
TRAF1TNF receptor-associated factor 10.131
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.129
CXCL3chemokine (C-X-C motif) ligand 30.129
BTN3A1butyrophilin, subfamily 3, member A10.125
TAL1T-cell acute lymphocytic leukemia 10.125
GRAP2GRB2-related adaptor protein 20.121
CCR1chemokine (C-C motif) receptor 10.118
BIDBH3 interacting domain death agonist0.117
AOAHacyloxyacyl hydrolase (neutrophil)0.114
CD3GCD3g molecule, gamma (CD3-TCR complex)0.112
IL1R2interleukin 1 receptor, type II0.110
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.109
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.108
HCKhemopoietic cell kinase0.107
CD1CCD1c molecule0.106
SLAMF1signaling lymphocytic activation molecule family member 10.106
CSKc-src tyrosine kinase0.104
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-Db1RT1 class II, locus Db10.209
RT1-DaRT1 class II, locus Da0.132
Cd247Cd247 molecule0.115
TcrbT-cell receptor beta chain0.088
RT1-BaRT1 class II, locus Ba0.064
Cd5Cd5 molecule0.052
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.050
Lcp1lymphocyte cytosolic protein 10.048
Cd53Cd53 molecule0.047
Il10interleukin 100.046
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.045
Cd37CD37 molecule0.042
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.040
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.040
Il1binterleukin 1 beta0.038
Ptger4prostaglandin E receptor 4 (subtype EP4)0.036
Gzmkgranzyme K0.035
Ptprcprotein tyrosine phosphatase, receptor type, C0.033
KlKlotho0.032
Sash3SAM and SH3 domain containing 30.032
Klrd1killer cell lectin-like receptor, subfamily D, member 10.031
Cd2Cd2 molecule0.029
Hckhemopoietic cell kinase0.029
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.028
Calcrcalcitonin receptor0.027
Il1rl1interleukin 1 receptor-like 10.027
Itgadintegrin, alpha D0.025
Plinperilipin0.024
Trpm8transient receptor potential cation channel, subfamily M, member 80.024
Ncr1natural cytotoxicity triggering receptor 10.024
Mmp10matrix metallopeptidase 100.024
Prss1protease, serine, 1 (trypsin 1)0.024
Il1r1interleukin 1 receptor, type I0.024
Inpp5dinositol polyphosphate-5-phosphatase D0.023
Syt8synaptotagmin VIII0.023
Ccl5chemokine (C-C motif) ligand 50.023
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.023
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.023
Prl8a9prolactin family 8, subfamily a, member 90.022
Ptafrplatelet-activating factor receptor0.022
Arhgap4Rho GTPase activating protein 40.022
Pspparotid secretory protein0.022
Scn11asodium channel, voltage-gated, type XI, alpha0.021
Vipvasoactive intestinal peptide0.020
Vom1r90vomeronasal 1 receptor 900.020
Nkg7natural killer cell group 7 sequence0.019
Olr1500olfactory receptor 15000.019
Reg3gregenerating islet-derived 3 gamma0.019
Il2rbinterleukin 2 receptor, beta0.019
Cfpcomplement factor properdin0.019
Itgb7integrin, beta 70.019
Oprk1opioid receptor, kappa 10.018
Zbp1Z-DNA binding protein 10.018
Spnsialophorin0.018
Reg3bregenerating islet-derived 3 beta0.017
Impg2interphotoreceptor matrix proteoglycan 20.017
Inhbeinhibin beta E0.017
Pthparathyroid hormone0.017
Csn1s1casein alpha s10.017
Npy5rneuropeptide Y receptor Y50.017
Trhthyrotropin releasing hormone0.017
Lhfpl2lipoma HMGIC fusion partner-like 20.017
Olr1496olfactory receptor 14960.016
Dnase1l3deoxyribonuclease 1-like 30.016
Ucnurocortin0.015
Ccr5chemokine (C-C motif) receptor 50.015
Il6interleukin 60.015
Laptm5lysosomal protein transmembrane 50.015
Crisp1cysteine-rich secretory protein 10.015
Crygccrystallin, gamma C0.015
Chrnb3cholinergic receptor, nicotinic, beta 30.015
Il4interleukin 40.014
Kcnv1potassium channel, subfamily V, member 10.014
Slco1a5solute carrier organic anion transporter family, member 1a50.014
Ptpn6protein tyrosine phosphatase, non-receptor type 60.014
Ugt2b7UDP glucuronosyltransferase 2 family, polypeptide B70.014
Pmfbp1polyamine modulated factor 1 binding protein 10.014
FaslgFas ligand (TNF superfamily, member 6)0.014
Srd5a2steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)0.014
Olaholeoyl-ACP hydrolase0.014
Napsanapsin A aspartic peptidase0.014
Kcng3potassium voltage-gated channel, subfamily G, member 30.014
Psg19pregnancy specific glycoprotein 190.014
Dgkgdiacylglycerol kinase, gamma0.014
Vom2r32vomeronasal 2 receptor, 320.014
Scp2sterol carrier protein 20.014
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.014
Casp1caspase 10.013
LOC689770similar to osteoclast inhibitory lectin0.013
Gja3gap junction protein, alpha 30.013
Ncf4neutrophil cytosolic factor 40.013
Mamdc4MAM domain containing 40.013
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.013
Metmet proto-oncogene0.013
Oprl1opiate receptor-like 10.013
Bin2bridging integrator 20.013
Npffr1neuropeptide FF receptor 10.012
Sellselectin L0.012
Ugt8UDP glycosyltransferase 80.012
Cpxm2carboxypeptidase X (M14 family), member 20.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism