The network for 'regulation of mononuclear cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mononuclear cell proliferation

Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.

NameDescriptionProbabilityFunc Analog Organism
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.997
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.992
LCKlymphocyte-specific protein tyrosine kinase0.990
FGFR2fibroblast growth factor receptor 20.982
PTPN6protein tyrosine phosphatase, non-receptor type 60.981
TRAF1TNF receptor-associated factor 10.977
LATlinker for activation of T cells0.945
BIRC3baculoviral IAP repeat containing 30.934
CD80CD80 molecule0.933
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.927
HLA-Fmajor histocompatibility complex, class I, F0.898
B2Mbeta-2-microglobulin0.896
SYKspleen tyrosine kinase0.888
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.887
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.887
ICAM1intercellular adhesion molecule 10.855
HLA-Gmajor histocompatibility complex, class I, G0.849
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.840
PTPRCprotein tyrosine phosphatase, receptor type, C0.829
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.817
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.816
HLA-Bmajor histocompatibility complex, class I, B0.803
CD2CD2 molecule0.797
BTN3A3butyrophilin, subfamily 3, member A30.797
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.776
CCR5chemokine (C-C motif) receptor 50.776
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.774
IL4Rinterleukin 4 receptor0.767
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.720
SOCS3suppressor of cytokine signaling 30.705
BTN3A1butyrophilin, subfamily 3, member A10.703
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.702
GRB2growth factor receptor-bound protein 20.644
IL10RAinterleukin 10 receptor, alpha0.644
CTLA4cytotoxic T-lymphocyte-associated protein 40.630
IL1R1interleukin 1 receptor, type I0.602
CD247CD247 molecule0.593
SHC1SHC (Src homology 2 domain containing) transforming protein 10.583
BCL2L1BCL2-like 10.578
TANKTRAF family member-associated NFKB activator0.577
JAK1Janus kinase 10.577
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.569
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.567
CXCL9chemokine (C-X-C motif) ligand 90.554
BCL2B-cell CLL/lymphoma 20.552
BTN3A2butyrophilin, subfamily 3, member A20.551
IL2RBinterleukin 2 receptor, beta0.542
ABI1abl-interactor 10.540
CD1CCD1c molecule0.534
CCL4chemokine (C-C motif) ligand 40.531
CD86CD86 molecule0.527
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.523
CCR7chemokine (C-C motif) receptor 70.518
IRF4interferon regulatory factor 40.516
IL1Binterleukin 1, beta0.501
HLA-Emajor histocompatibility complex, class I, E0.482
CD40CD40 molecule, TNF receptor superfamily member 50.482
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.472
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.457
BCL2L11BCL2-like 11 (apoptosis facilitator)0.444
HLA-Cmajor histocompatibility complex, class I, C0.443
IL8interleukin 80.439
FASLGFas ligand (TNF superfamily, member 6)0.435
PTPN22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.428
SIGLEC7sialic acid binding Ig-like lectin 70.412
EGFRepidermal growth factor receptor0.411
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.393
BRCA1breast cancer 1, early onset0.392
FGF1fibroblast growth factor 1 (acidic)0.383
TRAF3TNF receptor-associated factor 30.375
HLA-Amajor histocompatibility complex, class I, A0.374
CASP9caspase 9, apoptosis-related cysteine peptidase0.373
IL2RGinterleukin 2 receptor, gamma0.353
STAT4signal transducer and activator of transcription 40.348
TICAM2toll-like receptor adaptor molecule 20.336
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.321
SH2D1ASH2 domain containing 1A0.308
CXCL10chemokine (C-X-C motif) ligand 100.307
CD33CD33 molecule0.305
CCR1chemokine (C-C motif) receptor 10.301
IFNGinterferon, gamma0.297
CASP8caspase 8, apoptosis-related cysteine peptidase0.295
IFNGR1interferon gamma receptor 10.292
CFLARCASP8 and FADD-like apoptosis regulator0.291
CCL8chemokine (C-C motif) ligand 80.290
LTAlymphotoxin alpha (TNF superfamily, member 1)0.279
BTKBruton agammaglobulinemia tyrosine kinase0.276
TNFAIP3tumor necrosis factor, alpha-induced protein 30.274
PAX3paired box 30.272
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.271
LST1leukocyte specific transcript 10.270
PILRApaired immunoglobin-like type 2 receptor alpha0.269
MYD88myeloid differentiation primary response gene (88)0.269
IL10interleukin 100.268
IGF2insulin-like growth factor 2 (somatomedin A)0.261
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.259
SOS1son of sevenless homolog 1 (Drosophila)0.257
TFF1trefoil factor 10.255
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.247
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.245
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-DaRT1 class II, locus Da0.881
RT1-BaRT1 class II, locus Ba0.873
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.836
Cd247Cd247 molecule0.759
Cd37CD37 molecule0.714
RT1-Db1RT1 class II, locus Db10.555
RT1-BbRT1 class II, locus Bb0.533
RT1-DMbRT1 class II, locus DMb0.502
RT1-DMaRT1 class II, locus DMa0.393
Ptprcprotein tyrosine phosphatase, receptor type, C0.227
Lyz2lysozyme 20.210
Inpp5dinositol polyphosphate-5-phosphatase D0.187
Hckhemopoietic cell kinase0.147
Ciitaclass II, major histocompatibility complex, transactivator0.122
Cd44Cd44 molecule0.122
Arpc1bactin related protein 2/3 complex, subunit 1B0.118
Laptm5lysosomal protein transmembrane 50.116
Cd53Cd53 molecule0.114
Aif1allograft inflammatory factor 10.110
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.085
Il18interleukin 180.083
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.082
Il1binterleukin 1 beta0.076
Cd2Cd2 molecule0.075
Gzmkgranzyme K0.072
Serpinb1aserine (or cysteine) proteinase inhibitor, clade B, member 1a0.071
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.062
Anxa2annexin A20.060
Casp1caspase 10.054
Ccr5chemokine (C-C motif) receptor 50.053
Il6interleukin 60.053
Il10interleukin 100.051
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.050
Metmet proto-oncogene0.046
Spnsialophorin0.043
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.043
Aldh6a1aldehyde dehydrogenase 6 family, member A10.042
Csn2casein beta0.041
C1qbcomplement component 1, q subcomponent, B chain0.040
Il7rinterleukin 7 receptor0.039
Il2rbinterleukin 2 receptor, beta0.038
Cd38CD38 molecule0.038
Nkg7natural killer cell group 7 sequence0.038
Reg3gregenerating islet-derived 3 gamma0.037
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.037
Smgbneonatal submandibular gland protein B0.037
MGC112715hypothetical protein LOC6908990.037
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.036
Lcp2lymphocyte cytosolic protein 20.036
Ptger4prostaglandin E receptor 4 (subtype EP4)0.036
Cfpcomplement factor properdin0.036
Tacr2tachykinin receptor 20.035
Mmp10matrix metallopeptidase 100.035
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.035
Prss3protease, serine, 30.034
Slfn2schlafen 20.034
Scn11asodium channel, voltage-gated, type XI, alpha0.034
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.033
Napsanapsin A aspartic peptidase0.033
Ctla4cytotoxic T-lymphocyte-associated protein 40.031
Vipvasoactive intestinal peptide0.030
Cd5Cd5 molecule0.030
Il1rl1interleukin 1 receptor-like 10.030
Gpr20G protein-coupled receptor 200.030
Lcp1lymphocyte cytosolic protein 10.029
Il1r1interleukin 1 receptor, type I0.029
Tas2r123taste receptor, type 2, member 1230.029
Lef1lymphoid enhancer binding factor 10.029
Pde3aphosphodiesterase 3A, cGMP inhibited0.029
Arhgap4Rho GTPase activating protein 40.027
Krt14keratin 140.027
Ctsscathepsin S0.027
Ptpn6protein tyrosine phosphatase, non-receptor type 60.027
Socs3suppressor of cytokine signaling 30.027
Retret proto-oncogene0.026
Prl7a4prolactin family 7, subfamily a, member 40.026
Grngranulin0.026
Sellselectin L0.026
Cd4Cd4 molecule0.025
Map4k1mitogen activated protein kinase kinase kinase kinase 10.025
Ccl3chemokine (C-C motif) ligand 30.025
Psd4pleckstrin and Sec7 domain containing 40.025
Capgcapping protein (actin filament), gelsolin-like0.025
Bin2bridging integrator 20.025
Hpxhemopexin0.024
Cd86CD86 molecule0.024
Fgfr2fibroblast growth factor receptor 20.024
Cd22CD22 molecule0.024
Calcrlcalcitonin receptor-like0.024
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.024
Ncr1natural cytotoxicity triggering receptor 10.023
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.023
Sash3SAM and SH3 domain containing 30.023
Pmfbp1polyamine modulated factor 1 binding protein 10.023
Anxa1annexin A10.023
Fam108b1family with sequence similarity 108, member B10.022
Vav1vav 1 guanine nucleotide exchange factor0.022
Impg2interphotoreceptor matrix proteoglycan 20.022
MosMoloney sarcoma oncogene0.022
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.022
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism