The network for 'response to muramyl dipeptide' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to muramyl dipeptide

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.

NameDescriptionProbabilityFunc Analog Organism
BIRC3baculoviral IAP repeat containing 31.000
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.978
STAT2signal transducer and activator of transcription 2, 113kDa0.876
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.842
NOTCH3notch 30.674
NOTCH1notch 10.343
RIPK3receptor-interacting serine-threonine kinase 30.340
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.313
MARK2MAP/microtubule affinity-regulating kinase 20.301
IRF1interferon regulatory factor 10.265
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.257
TRAF1TNF receptor-associated factor 10.245
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.222
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.200
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.185
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.146
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.099
MAP3K8mitogen-activated protein kinase kinase kinase 80.094
HLA-Amajor histocompatibility complex, class I, A0.063
NOTCH2notch 20.061
JUNjun proto-oncogene0.055
TNIP2TNFAIP3 interacting protein 20.051
GBP5guanylate binding protein 50.050
JAG1jagged 10.048
TRAF3TNF receptor-associated factor 30.045
CASP7caspase 7, apoptosis-related cysteine peptidase0.037
TNFAIP3tumor necrosis factor, alpha-induced protein 30.034
TRIM21tripartite motif containing 210.033
MAP3K14mitogen-activated protein kinase kinase kinase 140.033
ACTBactin, beta0.033
ZNFX1zinc finger, NFX1-type containing 10.031
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.028
BCL3B-cell CLL/lymphoma 30.027
NCOA3nuclear receptor coactivator 30.027
PSME1proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)0.026
MAP2K6mitogen-activated protein kinase kinase 60.025
TNFtumor necrosis factor0.025
ANGangiogenin, ribonuclease, RNase A family, 50.024
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.023
MAML1mastermind-like 1 (Drosophila)0.022
EFNB2ephrin-B20.021
XIAPX-linked inhibitor of apoptosis0.021
NFKBIZnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.021
CASP9caspase 9, apoptosis-related cysteine peptidase0.021
KLF5Kruppel-like factor 5 (intestinal)0.020
RIPK2receptor-interacting serine-threonine kinase 20.020
CFLARCASP8 and FADD-like apoptosis regulator0.020
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.019
ANKRD28ankyrin repeat domain 280.019
OSBPL3oxysterol binding protein-like 30.018
TRAF2TNF receptor-associated factor 20.018
DUSP1dual specificity phosphatase 10.018
MAP2K1mitogen-activated protein kinase kinase 10.018
IRF6interferon regulatory factor 60.018
CCDC50coiled-coil domain containing 500.018
TRIM22tripartite motif containing 220.017
PRMT2protein arginine methyltransferase 20.017
IFNAR2interferon (alpha, beta and omega) receptor 20.017
MAPK1mitogen-activated protein kinase 10.017
MAP2K3mitogen-activated protein kinase kinase 30.017
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.017
IRF2interferon regulatory factor 20.016
HSPA1Lheat shock 70kDa protein 1-like0.016
BTN3A1butyrophilin, subfamily 3, member A10.016
MKNK1MAP kinase interacting serine/threonine kinase 10.016
CASP3caspase 3, apoptosis-related cysteine peptidase0.016
ZFP36L1zinc finger protein 36, C3H type-like 10.016
TSC1tuberous sclerosis 10.016
IRF8interferon regulatory factor 80.015
FOXO1forkhead box O10.015
RAI14retinoic acid induced 140.015
THRAP3thyroid hormone receptor associated protein 30.015
MKNK2MAP kinase interacting serine/threonine kinase 20.015
CD86CD86 molecule0.015
MPRIPmyosin phosphatase Rho interacting protein0.015
IL15RAinterleukin 15 receptor, alpha0.014
FAM82A2family with sequence similarity 82, member A20.014
SRGAP2SLIT-ROBO Rho GTPase activating protein 20.014
MYO1Dmyosin ID0.014
ADARadenosine deaminase, RNA-specific0.014
USP4ubiquitin specific peptidase 4 (proto-oncogene)0.014
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.014
PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)0.014
MAXMYC associated factor X0.013
RNF168ring finger protein 1680.013
TNFAIP2tumor necrosis factor, alpha-induced protein 20.013
RALGPS2Ral GEF with PH domain and SH3 binding motif 20.013
MDM2Mdm2 p53 binding protein homolog (mouse)0.013
RNF19Bring finger protein 19B0.013
YAP1Yes-associated protein 10.013
TRIM38tripartite motif containing 380.013
POLHpolymerase (DNA directed), eta0.013
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.013
CASP8caspase 8, apoptosis-related cysteine peptidase0.013
MAPK3mitogen-activated protein kinase 30.013
HMHA1histocompatibility (minor) HA-10.013
HCP5HLA complex P50.013
ETV6ets variant 60.013
EPB41L3erythrocyte membrane protein band 4.1-like 30.012
MAP3K2mitogen-activated protein kinase kinase kinase 20.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1001.000
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.999
Notch1Notch gene homolog 1 (Drosophila)0.996
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.982
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.955
Mapk14mitogen-activated protein kinase 140.867
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.752
Dll1delta-like 1 (Drosophila)0.692
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.454
Map3k14mitogen-activated protein kinase kinase kinase 140.424
Psen1presenilin 10.252
Tnftumor necrosis factor0.233
Tnip1TNFAIP3 interacting protein 10.160
Bcl3B-cell leukemia/lymphoma 30.125
Traf6TNF receptor-associated factor 60.116
Mapk11mitogen-activated protein kinase 110.071
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.071
Ikbkbinhibitor of kappaB kinase beta0.070
Ighimmunoglobulin heavy chain complex0.066
Socs1suppressor of cytokine signaling 10.065
Atf2activating transcription factor 20.056
Irf1interferon regulatory factor 10.049
Cd44CD44 antigen0.046
Psen2presenilin 20.044
Il4rainterleukin 4 receptor, alpha0.044
Notch2Notch gene homolog 2 (Drosophila)0.042
Jag2jagged 20.039
Egfl7EGF-like domain 70.030
PycardPYD and CARD domain containing0.029
Ooepoocyte expressed protein homolog (dog)0.028
Tnfaip3tumor necrosis factor, alpha-induced protein 30.026
Mapkapk2MAP kinase-activated protein kinase 20.025
Traf2TNF receptor-associated factor 20.024
Cyldcylindromatosis (turban tumor syndrome)0.022
Ikzf1IKAROS family zinc finger 10.022
Myd88myeloid differentiation primary response gene 880.021
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.020
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.020
NrarpNotch-regulated ankyrin repeat protein0.017
Bcl6B-cell leukemia/lymphoma 60.016
Cd40CD40 antigen0.014
JunbJun-B oncogene0.013
Il4interleukin 40.013
Map3k8mitogen-activated protein kinase kinase kinase 80.012
Socs3suppressor of cytokine signaling 30.012
Nlrp3NLR family, pyrin domain containing 30.012
Prkcdprotein kinase C, delta0.011
Mib1mindbomb homolog 1 (Drosophila)0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Errfi1ERBB receptor feedback inhibitor 10.205
Zfp36zinc finger protein 360.101
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.073
Junbjun B proto-oncogene0.053
Sgk1serum/glucocorticoid regulated kinase 10.038
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.024
Dusp1dual specificity phosphatase 10.020
Ddit4DNA-damage-inducible transcript 40.019
Klf6Kruppel-like factor 60.017
Rgl2ral guanine nucleotide dissociation stimulator-like 20.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism