The network for 'regulation of myeloid cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of myeloid cell differentiation

Any process that modulates the frequency, rate or extent of myeloid cell differentiation.

NameDescriptionProbabilityFunc Analog Organism
CASP8caspase 8, apoptosis-related cysteine peptidase1.000
CREBBPCREB binding protein1.000
ESR1estrogen receptor 10.997
JUNjun proto-oncogene0.995
MDM2Mdm2 p53 binding protein homolog (mouse)0.993
CCR5chemokine (C-C motif) receptor 50.986
SP1Sp1 transcription factor0.981
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.973
IL8interleukin 80.951
CASP10caspase 10, apoptosis-related cysteine peptidase0.944
FASFas (TNF receptor superfamily, member 6)0.941
TAL1T-cell acute lymphocytic leukemia 10.937
TRAF1TNF receptor-associated factor 10.935
ZNF43zinc finger protein 430.931
CASP3caspase 3, apoptosis-related cysteine peptidase0.930
SMAD4SMAD family member 40.930
CXCL2chemokine (C-X-C motif) ligand 20.909
BIRC3baculoviral IAP repeat containing 30.908
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.899
NOTCH1notch 10.894
FASLGFas ligand (TNF superfamily, member 6)0.893
PBX1pre-B-cell leukemia homeobox 10.891
XIAPX-linked inhibitor of apoptosis0.880
ARandrogen receptor0.879
CXCL9chemokine (C-X-C motif) ligand 90.861
HIST2H2BEhistone cluster 2, H2be0.827
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.819
SETD8SET domain containing (lysine methyltransferase) 80.813
CXCL3chemokine (C-X-C motif) ligand 30.802
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.801
CCL5chemokine (C-C motif) ligand 50.799
RUNX1runt-related transcription factor 10.789
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.789
IL4Rinterleukin 4 receptor0.783
HSPA1Aheat shock 70kDa protein 1A0.778
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.777
TGFB1transforming growth factor, beta 10.772
CFLARCASP8 and FADD-like apoptosis regulator0.768
PTPN6protein tyrosine phosphatase, non-receptor type 60.761
SH2D4ASH2 domain containing 4A0.757
TRAF3TNF receptor-associated factor 30.748
CXCL10chemokine (C-X-C motif) ligand 100.721
HIST1H2AJhistone cluster 1, H2aj0.714
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.714
NFE2L2nuclear factor (erythroid-derived 2)-like 20.698
HIST1H3Dhistone cluster 1, H3d0.692
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.673
HOXB5homeobox B50.671
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.668
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.649
HSPA1Bheat shock 70kDa protein 1B0.627
CCL4chemokine (C-C motif) ligand 40.617
IL2RBinterleukin 2 receptor, beta0.617
CCND1cyclin D10.616
WASLWiskott-Aldrich syndrome-like0.615
PILRApaired immunoglobin-like type 2 receptor alpha0.612
FADDFas (TNFRSF6)-associated via death domain0.611
SMAD7SMAD family member 70.609
IL1Binterleukin 1, beta0.607
HIST1H2AEhistone cluster 1, H2ae0.604
ZNF253zinc finger protein 2530.596
ZNF273zinc finger protein 2730.594
RIPK2receptor-interacting serine-threonine kinase 20.587
BMP2bone morphogenetic protein 20.584
MAPK8mitogen-activated protein kinase 80.580
IL6interleukin 6 (interferon, beta 2)0.562
HIST1H4Dhistone cluster 1, H4d0.561
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.551
SMAD2SMAD family member 20.541
JAG1jagged 10.538
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.537
ZNF675zinc finger protein 6750.535
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.520
IFNGinterferon, gamma0.512
SMAD3SMAD family member 30.501
CCR7chemokine (C-C motif) receptor 70.492
CXCL11chemokine (C-X-C motif) ligand 110.490
HDAC3histone deacetylase 30.488
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.468
JUPjunction plakoglobin0.462
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.460
CTR9Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.459
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.449
CD40CD40 molecule, TNF receptor superfamily member 50.449
HIST1H2AMhistone cluster 1, H2am0.445
PTPN1protein tyrosine phosphatase, non-receptor type 10.434
DAXXdeath-domain associated protein0.428
HIST1H2AIhistone cluster 1, H2ai0.428
ZNF708zinc finger protein 7080.396
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)0.391
BCAR1breast cancer anti-estrogen resistance 10.385
CCL20chemokine (C-C motif) ligand 200.376
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.375
HIST1H1Ehistone cluster 1, H1e0.368
JUNBjun B proto-oncogene0.365
HIST1H2BGhistone cluster 1, H2bg0.365
HIST1H2ABhistone cluster 1, H2ab0.361
HOXA10homeobox A100.358
SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)0.355
GHRgrowth hormone receptor0.354
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tal1T-cell acute lymphocytic leukemia 10.391
gata6GATA-binding protein 60.318
pax2apaired box gene 2a0.255
nf1aneurofibromin 1a0.253
hoxc8ahomeo box C8a0.206
mpxmyeloid-specific peroxidase0.202
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.180
spry4sprouty (Drosophila) homolog 40.124
hhexhematopoietically expressed homeobox0.114
mycamyelocytomatosis oncogene a0.100
hoxb5bhomeo box B5b0.093
csf1racolony stimulating factor 1 receptor, a0.086
hmgb2bhigh-mobility group box 2b0.084
wu:fv91b12wu:fv91b120.082
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.076
hoxd4ahomeo box D4a0.075
drldraculin0.073
klf4Kruppel-like factor 40.069
mef2camyocyte enhancer factor 2ca0.069
cxcr4bchemokine (C-X-C motif), receptor 4b0.068
lmo4aLIM domain only 4a0.067
hbbe1.1hemoglobin beta embryonic-1.10.065
runx1runt-related transcription factor 10.063
mitfamicrophthalmia-associated transcription factor a0.063
fn1fibronectin 10.062
dhrs3adehydrogenase/reductase (SDR family) member 3a0.060
aplnraapelin receptor a0.060
alas2aminolevulinate, delta-, synthetase 20.058
hmgb1ahigh-mobility group box 1a0.058
bmp2bbone morphogenetic protein 2b0.058
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.053
osr1odd-skipped related 1 (Drosophila)0.053
spi1lspleen focus forming virus (SFFV) proviral integration oncogene spi1 like0.052
etv2ets variant gene 20.050
lfnglunatic fringe homolog0.049
kitakit receptor a0.049
hmgb1bhigh-mobility group box 1b0.049
rag1recombination activating gene 10.047
cdx4caudal type homeo box transcription factor 40.046
plcg1phospholipase C, gamma 10.043
hmgb3ahigh-mobility group box 3a0.043
raraaretinoic acid receptor, alpha a0.041
tfebtranscription factor EB0.040
dlddeltaD0.039
tfap2atranscription factor AP-2 alpha0.037
gli2aGLI-Kruppel family member GLI2a0.037
tlr3toll-like receptor 30.037
lhcgrluteinizing hormone/choriogonadotropin receptor0.036
tlr21toll-like receptor 210.036
hmgb2ahigh-mobility group box 2a0.036
sox3SRY-box containing gene 30.036
paqr7bprogestin and adipoQ receptor family member VII, b0.035
gdf6agrowth differentiation factor 6a0.034
notch3notch homolog 30.034
rargaretinoic acid receptor gamma a0.033
hand2heart and neural crest derivatives expressed transcript 20.032
socs3asuppressor of cytokine signaling 3a0.032
f2rcoagulation factor II (thrombin) receptor0.028
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.027
mef2cbmyocyte enhancer factor 2cb0.026
tcf12transcription factor 120.025
tfe3btranscription factor binding to IGHM enhancer 3b0.025
mcoln1mucolipin 10.024
lmo2LIM domain only 2 (rhombotin-like 1)0.024
glcci1glucocorticoid induced transcript 10.024
zgc:110340zgc:1103400.024
sox2SRY-box containing gene 20.023
trim33tripartite motif-containing 330.023
ewsr1bEwing sarcoma breakpoint region 1b0.022
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.021
flot1flotillin 10.021
hbae1hemoglobin alpha embryonic-10.020
acvr2bactivin receptor IIb0.020
eporerythropoietin receptor0.020
cdk10cyclin-dependent kinase 100.020
pdcd2programmed cell death 20.019
hoxd10ahomeo box D10a0.019
cfl2lcofilin 2, like0.019
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.019
bcl2l10BCL2-like 10 (apoptosis facilitator)0.019
hbaa1hemoglobin alpha adult-10.019
ca2carbonic anhydrase II0.018
cpoxcoproporphyrinogen oxidase0.018
LOC566708FL cytokine receptor-like0.018
atf3activating transcription factor 30.018
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.018
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.018
bcl2B-cell leukemia/lymphoma 20.017
metmet proto-oncogene (hepatocyte growth factor receptor)0.017
si:dkey-12o15.1si:dkey-12o15.10.017
mmrn2amultimerin 2a0.016
sept6septin 60.016
wu:fb58e05wu:fb58e050.016
junbljun B proto-oncogene, like0.016
prox1prospero-related homeobox gene 10.016
sf3b1splicing factor 3b, subunit 10.016
enc1ectodermal-neural cortex (with BTB-like domain)0.016
cmybtranscription factor cmyb0.016
bcl2l1bcl2-like 10.016
nf1bneurofibromin 1b0.015
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.998
Ptenphosphatase and tensin homolog0.995
Notch1Notch gene homolog 1 (Drosophila)0.962
Pbx1pre B-cell leukemia transcription factor 10.959
Tgfb1transforming growth factor, beta 10.952
Ikzf1IKAROS family zinc finger 10.950
Csf1colony stimulating factor 1 (macrophage)0.948
Trp53transformation related protein 530.933
Hoxa10homeobox A100.928
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.907
Fshrfollicle stimulating hormone receptor0.906
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.902
Runx1runt related transcription factor 10.896
Hes1hairy and enhancer of split 1 (Drosophila)0.878
Fgfr2fibroblast growth factor receptor 20.864
Robo1roundabout homolog 1 (Drosophila)0.863
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.849
Hoxa5homeobox A50.844
Smad3MAD homolog 3 (Drosophila)0.837
Arandrogen receptor0.833
Cav1caveolin 1, caveolae protein0.816
Pax8paired box gene 80.805
Nos3nitric oxide synthase 3, endothelial cell0.802
Mapk14mitogen-activated protein kinase 140.801
Hoxa11homeobox A110.780
Notch2Notch gene homolog 2 (Drosophila)0.775
Kitlkit ligand0.748
Ascl1achaete-scute complex homolog 1 (Drosophila)0.744
Ctnnb1catenin (cadherin associated protein), beta 10.741
Gata1GATA binding protein 10.739
CblCasitas B-lineage lymphoma0.731
Tnftumor necrosis factor0.728
Hoxc8homeobox C80.724
Leprleptin receptor0.706
Ppargperoxisome proliferator activated receptor gamma0.704
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.696
Tal1T-cell acute lymphocytic leukemia 10.694
Pax6paired box gene 60.680
Esr1estrogen receptor 1 (alpha)0.676
Dll1delta-like 1 (Drosophila)0.666
Adam17a disintegrin and metallopeptidase domain 170.648
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.636
Prkceprotein kinase C, epsilon0.632
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.630
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.630
Epas1endothelial PAS domain protein 10.629
Hif1ahypoxia inducible factor 1, alpha subunit0.626
Ptgs2prostaglandin-endoperoxide synthase 20.612
Ptpn11protein tyrosine phosphatase, non-receptor type 110.606
Hoxb6homeobox B60.605
Pitx2paired-like homeodomain transcription factor 20.592
Il6stinterleukin 6 signal transducer0.563
Hoxa13homeobox A130.550
FasFas (TNF receptor superfamily member 6)0.545
Hoxb5homeobox B50.536
Rb1retinoblastoma 10.532
Kitkit oncogene0.531
Foxc1forkhead box C10.528
Hoxa9homeobox A90.515
Ltblymphotoxin B0.512
Inpp5dinositol polyphosphate-5-phosphatase D0.509
Tnfaip3tumor necrosis factor, alpha-induced protein 30.508
Cyldcylindromatosis (turban tumor syndrome)0.504
Hoxc4homeobox C40.503
Hoxa1homeobox A10.503
Ldb1LIM domain binding 10.500
JunJun oncogene0.499
Lmx1bLIM homeobox transcription factor 1 beta0.493
JunbJun-B oncogene0.490
Hoxb3homeobox B30.489
Ldb3LIM domain binding 30.478
Eporerythropoietin receptor0.461
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.457
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.449
Nhlh1nescient helix loop helix 10.446
Cxcr5chemokine (C-X-C motif) receptor 50.436
Rbl2retinoblastoma-like 20.433
Ptf1apancreas specific transcription factor, 1a0.429
Kiss1KiSS-1 metastasis-suppressor0.426
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.415
Atf2activating transcription factor 20.414
Id1inhibitor of DNA binding 10.410
Shox2short stature homeobox 20.409
Lef1lymphoid enhancer binding factor 10.408
Stat5bsignal transducer and activator of transcription 5B0.406
Snai1snail homolog 1 (Drosophila)0.403
Nr3c1nuclear receptor subfamily 3, group C, member 10.398
Hoxb4homeobox B40.398
Fli1Friend leukemia integration 10.395
Sox11SRY-box containing gene 110.394
Smad7MAD homolog 7 (Drosophila)0.391
Ncoa3nuclear receptor coactivator 30.389
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.386
Nr5a1nuclear receptor subfamily 5, group A, member 10.384
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.377
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.375
Hdac7histone deacetylase 70.368
Hoxb9homeobox B90.367
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.362
BtkBruton agammaglobulinemia tyrosine kinase0.359
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dusp1dual specificity phosphatase 10.429
Errfi1ERBB receptor feedback inhibitor 10.388
Zfp36zinc finger protein 360.347
C1qbcomplement component 1, q subcomponent, B chain0.186
Cd86CD86 molecule0.166
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.141
Fcn1ficolin (collagen/fibrinogen domain containing) 10.130
Atf3activating transcription factor 30.116
Ptprcprotein tyrosine phosphatase, receptor type, C0.111
Egr2early growth response 20.109
Cfpcomplement factor properdin0.099
JunJun oncogene0.099
Casp2caspase 20.088
Nkg7natural killer cell group 7 sequence0.082
Cd247Cd247 molecule0.081
Prf1perforin 1 (pore forming protein)0.077
Klf4Kruppel-like factor 4 (gut)0.077
Kcnmb1potassium large conductance calcium-activated channel, subfamily M, beta member 10.071
Egr1early growth response 10.068
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.062
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.060
Guca2aguanylate cyclase activator 2a (guanylin)0.059
Ccl3chemokine (C-C motif) ligand 30.059
Mmp3matrix metallopeptidase 30.057
Il6interleukin 60.056
Rassf5Ras association (RalGDS/AF-6) domain family member 50.056
Junbjun B proto-oncogene0.056
Ccl4chemokine (C-C motif) ligand 40.055
H2afzH2A histone family, member Z0.052
Casp3caspase 30.051
Ier2immediate early response 20.051
Apoeapolipoprotein E0.045
Il8rbinterleukin 8 receptor, beta0.045
Rgs1regulator of G-protein signaling 10.043
Klf6Kruppel-like factor 60.040
Nme1non-metastatic cells 1, protein (NM23A) expressed in0.038
Il1ainterleukin 1 alpha0.035
CblCas-Br-M (murine) ecotropic retroviral transforming sequence0.034
Igsf6immunoglobulin superfamily, member 60.032
Il2rbinterleukin 2 receptor, beta0.031
Gzmmgranzyme M (lymphocyte met-ase 1)0.031
Zcchc6zinc finger, CCHC domain containing 60.031
Apex1APEX nuclease (multifunctional DNA repair enzyme) 10.030
Irs1insulin receptor substrate 10.030
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.028
Sostsclerosteosis0.028
Gpr20G protein-coupled receptor 200.028
Zfp36l2zinc finger protein 36, C3H type-like 20.027
Cks2CDC28 protein kinase regulatory subunit 20.027
Plauplasminogen activator, urokinase0.026
Klrd1killer cell lectin-like receptor, subfamily D, member 10.025
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.025
Gfi1growth factor independent 1 transcription repressor0.025
Ssr4signal sequence receptor, delta0.025
Polr2gpolymerase (RNA) II (DNA directed) polypeptide G0.024
Taldo1transaldolase 10.024
Umoduromodulin0.024
F13a1coagulation factor XIII, A1 polypeptide0.024
Akr1c1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.024
C1qacomplement component 1, q subcomponent, A chain0.024
Klhl6kelch-like 6 (Drosophila)0.023
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.023
Vcsa2variable coding sequence A20.023
Rassf1Ras association (RalGDS/AF-6) domain family member 10.022
Gna15guanine nucleotide binding protein, alpha 150.022
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.022
Acacbacetyl-Coenzyme A carboxylase beta0.022
Kdrkinase insert domain receptor0.022
Ctsscathepsin S0.021
Sgk1serum/glucocorticoid regulated kinase 10.021
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.020
Chmp2achromatin modifying protein 2A0.020
Gzmkgranzyme K0.020
Ccr5chemokine (C-C motif) receptor 50.020
Mmp13matrix metallopeptidase 130.019
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.019
Bhlhe40basic helix-loop-helix family, member e400.019
LOC100134871beta globin minor gene0.018
Expiextracellular proteinase inhibitor0.018
Pld4phospholipase D family, member 40.018
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.018
Hist1h2bahistone cluster 1, H2ba0.018
Grm5glutamate receptor, metabotropic 50.018
Slit3slit homolog 3 (Drosophila)0.018
Reg3bregenerating islet-derived 3 beta0.017
Pla2g2aphospholipase A2, group IIA (platelets, synovial fluid)0.017
Mmp9matrix metallopeptidase 90.017
Dnase1l3deoxyribonuclease 1-like 30.017
Prl6a1prolactin family 6, subfamily a, member 10.017
RGD1359529similar to chromosome 1 open reading frame 630.017
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.016
Fosl2fos-like antigen 20.016
Vom1r100vomeronasal 1 receptor 1000.016
Cfdcomplement factor D (adipsin)0.016
Ccl7chemokine (C-C motif) ligand 70.016
Bcl2B-cell CLL/lymphoma 20.015
Gifgastric intrinsic factor0.015
Ccl19chemokine (C-C motif) ligand 190.015
Cela1chymotrypsin-like elastase family, member 10.015
RGD1565784RGD15657840.015
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism