The network for 'regulation of calcium ion transmembrane transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of calcium ion transmembrane transport

Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.

NameDescriptionProbabilityFunc Analog Organism
GSTM1glutathione S-transferase mu 10.998
GSTM2glutathione S-transferase mu 2 (muscle)0.933
TBX5T-box 50.824
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.804
KIAA1683KIAA16830.715
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.679
CALM1calmodulin 1 (phosphorylase kinase, delta)0.613
DTNAdystrobrevin, alpha0.530
S100BS100 calcium binding protein B0.517
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.372
ARF3ADP-ribosylation factor 30.316
CRHcorticotropin releasing hormone0.284
PKD1polycystic kidney disease 1 (autosomal dominant)0.261
GSTM4glutathione S-transferase mu 40.172
ACVR1Bactivin A receptor, type IB0.149
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.149
ACTR1AARP1 actin-related protein 1 homolog A, centractin alpha (yeast)0.141
TRIM29tripartite motif containing 290.116
ADORA2Aadenosine A2a receptor0.114
GRB2growth factor receptor-bound protein 20.085
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.083
ORAI1ORAI calcium release-activated calcium modulator 10.082
MDM2Mdm2 p53 binding protein homolog (mouse)0.078
SH3BP2SH3-domain binding protein 20.066
CAPN2calpain 2, (m/II) large subunit0.063
GSTM3glutathione S-transferase mu 3 (brain)0.062
SYNMsynemin, intermediate filament protein0.059
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.057
AKAP6A kinase (PRKA) anchor protein 60.054
CAPZBcapping protein (actin filament) muscle Z-line, beta0.051
PSEN2presenilin 2 (Alzheimer disease 4)0.050
CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.050
CALCOCO2calcium binding and coiled-coil domain 20.049
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.048
TRPC1transient receptor potential cation channel, subfamily C, member 10.047
ARPC1Aactin related protein 2/3 complex, subunit 1A, 41kDa0.046
PYGMphosphorylase, glycogen, muscle0.046
MYO10myosin X0.045
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.043
MTORmechanistic target of rapamycin (serine/threonine kinase)0.041
DIAPH1diaphanous homolog 1 (Drosophila)0.041
RYR2ryanodine receptor 2 (cardiac)0.037
GNG5guanine nucleotide binding protein (G protein), gamma 50.035
GNG2guanine nucleotide binding protein (G protein), gamma 20.034
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.032
MYL3myosin, light chain 3, alkali; ventricular, skeletal, slow0.032
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.032
ZFYVE9zinc finger, FYVE domain containing 90.030
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.030
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.030
NDRG2NDRG family member 20.030
CASQ2calsequestrin 2 (cardiac muscle)0.029
EGFepidermal growth factor0.029
ATN1atrophin 10.029
UTRNutrophin0.027
NR4A3nuclear receptor subfamily 4, group A, member 30.027
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.026
GRB10growth factor receptor-bound protein 100.026
FXYD1FXYD domain containing ion transport regulator 10.026
LDB3LIM domain binding 30.026
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.024
ATP2A1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.024
GIGYF1GRB10 interacting GYF protein 10.023
SHC3SHC (Src homology 2 domain containing) transforming protein 30.023
MAPK4mitogen-activated protein kinase 40.023
APBB2amyloid beta (A4) precursor protein-binding, family B, member 20.023
MYBPC1myosin binding protein C, slow type0.022
ATP5J2ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F20.022
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)0.022
MYOM1myomesin 1, 185kDa0.022
CFL1cofilin 1 (non-muscle)0.022
LTBP4latent transforming growth factor beta binding protein 40.022
MYH6myosin, heavy chain 6, cardiac muscle, alpha0.021
HIF3Ahypoxia inducible factor 3, alpha subunit0.020
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.020
SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)0.020
CAV3caveolin 30.019
ACTC1actin, alpha, cardiac muscle 10.019
AP2M1adaptor-related protein complex 2, mu 1 subunit0.019
ABL2v-abl Abelson murine leukemia viral oncogene homolog 20.019
FAM189A2family with sequence similarity 189, member A20.019
CLTBclathrin, light chain B0.019
CKMcreatine kinase, muscle0.018
GSTM5glutathione S-transferase mu 50.018
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.018
MUSTN1musculoskeletal, embryonic nuclear protein 10.018
PTPN1protein tyrosine phosphatase, non-receptor type 10.017
ARHGEF4Rho guanine nucleotide exchange factor (GEF) 40.017
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.017
CKMT2creatine kinase, mitochondrial 2 (sarcomeric)0.017
RPS27Lribosomal protein S27-like0.017
MAP2K1mitogen-activated protein kinase kinase 10.017
AQP7aquaporin 70.017
LMOD1leiomodin 1 (smooth muscle)0.017
GNG7guanine nucleotide binding protein (G protein), gamma 70.017
TRAPPC1trafficking protein particle complex 10.017
SRPK3SRSF protein kinase 30.016
HRChistidine rich calcium binding protein0.016
SNTB1syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)0.016
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rab11Rab-protein 110.030
DlDelta0.029
escextra sexcombs0.025
eIF-4EEukaryotic initiation factor 4E0.021
DrefDNA replication-related element factor0.019
mrnmarionette0.018
armarmadillo0.017
dppdecapentaplegic0.016
saxsaxophone0.016
Nrx-IVNeurexin IV0.016
Ras85DRas oncogene at 85D0.015
E(z)Enhancer of zeste0.015
brmbrahma0.015
EgfrEpidermal growth factor receptor0.015
Rcd5Reduction in Cnn dots 50.015
NNotch0.014
l(2)03709lethal (2) 037090.014
Fcp1CG12252 gene product from transcript CG12252-RA0.014
ecdecdysoneless0.014
Pi3K92ECG4141 gene product from transcript CG4141-RB0.013
CG2182CG2182 gene product from transcript CG2182-RA0.013
TorTarget of rapamycin0.013
VangVan Gogh0.013
Saf-BScaffold attachment factor B0.012
RecQ4CG7487 gene product from transcript CG7487-RA0.012
Stat92ESignal-transducer and activator of transcription protein at 92E0.012
zf30CZinc finger protein 30C0.011
CatsupCatecholamines up0.011
mit(1)15mitotic 150.011
ptcpatched0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.712
Tbx5T-box 50.353
Spna1spectrin alpha 10.344
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.254
Ryr2ryanodine receptor 2, cardiac0.244
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.233
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.226
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.192
Ldb3LIM domain binding 30.181
Gnao1guanine nucleotide binding protein, alpha O0.163
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.158
Smyd1SET and MYND domain containing 10.155
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.152
Homer1homer homolog 1 (Drosophila)0.129
Epas1endothelial PAS domain protein 10.118
Stim1stromal interaction molecule 10.101
Casq2calsequestrin 20.094
Pax3paired box gene 30.092
Kcnq2potassium voltage-gated channel, subfamily Q, member 20.091
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.091
Grm1glutamate receptor, metabotropic 10.090
Kcnk3potassium channel, subfamily K, member 30.079
Pvalbparvalbumin0.078
Pygmmuscle glycogen phosphorylase0.073
Shc3src homology 2 domain-containing transforming protein C30.071
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.071
Sgcasarcoglycan, alpha (dystrophin-associated glycoprotein)0.071
Crhr1corticotropin releasing hormone receptor 10.068
Fgfr2fibroblast growth factor receptor 20.067
Nos1nitric oxide synthase 1, neuronal0.067
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.065
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.065
Ank1ankyrin 1, erythroid0.062
Eporerythropoietin receptor0.061
Cux2cut-like homeobox 20.061
Ghgrowth hormone0.058
Srpk3serine/arginine-rich protein specific kinase 30.058
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.058
Itpr1inositol 1,4,5-trisphosphate receptor 10.058
Ckmcreatine kinase, muscle0.057
Acheacetylcholinesterase0.057
Plcb1phospholipase C, beta 10.055
Dtnadystrobrevin alpha0.055
Spnb1spectrin beta 10.053
Foxe1forkhead box E10.053
Hpcahippocalcin0.053
Fgf22fibroblast growth factor 220.052
Inpp5jinositol polyphosphate 5-phosphatase J0.052
Cckbrcholecystokinin B receptor0.051
Vegfavascular endothelial growth factor A0.051
Chrm1cholinergic receptor, muscarinic 1, CNS0.049
Dag1dystroglycan 10.048
Rgs8regulator of G-protein signaling 80.047
AI118078expressed sequence AI1180780.047
Hand2heart and neural crest derivatives expressed transcript 20.047
Cdh15cadherin 150.046
Usp13ubiquitin specific peptidase 13 (isopeptidase T-3)0.045
Kcna7potassium voltage-gated channel, shaker-related subfamily, member 70.045
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.044
L1camL1 cell adhesion molecule0.043
Kcnj12potassium inwardly-rectifying channel, subfamily J, member 120.043
Spnb2spectrin beta 20.043
Actn2actinin alpha 20.042
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.041
Frmd5FERM domain containing 50.039
Art5ADP-ribosyltransferase 50.039
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.039
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.038
Limch1LIM and calponin homology domains 10.038
Nkx6-1NK6 homeobox 10.038
Nodalnodal0.038
St8sia5ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 50.038
Thrbthyroid hormone receptor beta0.038
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.038
Btrcbeta-transducin repeat containing protein0.037
Per3period homolog 3 (Drosophila)0.037
Fgf5fibroblast growth factor 50.037
Nrapnebulin-related anchoring protein0.037
Fgf10fibroblast growth factor 100.036
Pitx2paired-like homeodomain transcription factor 20.036
Hand1heart and neural crest derivatives expressed transcript 10.035
Sox9SRY-box containing gene 90.034
Tcf21transcription factor 210.034
Hoxd13homeobox D130.033
Mov10l1Moloney leukemia virus 10-like 10.033
Stim2stromal interaction molecule 20.032
Syncsyncoilin0.032
Nkx2-1NK2 homeobox 10.032
Map4k2mitogen-activated protein kinase kinase kinase kinase 20.032
Sept7septin 70.032
Ptprn2protein tyrosine phosphatase, receptor type, N polypeptide 20.031
Mybpc3myosin binding protein C, cardiac0.031
Casq1calsequestrin 10.031
Pip5k1bphosphatidylinositol-4-phosphate 5-kinase, type 1 beta0.030
Fgf9fibroblast growth factor 90.030
Scn5asodium channel, voltage-gated, type V, alpha0.030
Rpgrip1lRpgrip1-like0.030
Nognoggin0.029
Dmpkdystrophia myotonica-protein kinase0.029
Tuba8tubulin, alpha 80.029
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
S100a6S100 calcium binding protein A60.989
S100a10S100 calcium binding protein A100.874
Anxa1annexin A10.795
S100a4S100 calcium-binding protein A40.674
S100a9S100 calcium binding protein A90.579
S100a8S100 calcium binding protein A80.460
Lgals3lectin, galactoside-binding, soluble, 30.429
Anxa2annexin A20.426
Lgals1lectin, galactoside-binding, soluble, 10.377
Cripcysteine-rich intestinal protein0.294
S100a11S100 calcium binding protein A11 (calizzarin)0.277
Tspotranslocator protein0.274
Dynll1dynein light chain LC8-type 10.260
Pgam1phosphoglycerate mutase 1 (brain)0.199
Calm1calmodulin 10.184
Anxa5annexin A50.131
Tomm20translocase of outer mitochondrial membrane 20 homolog (yeast)0.130
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.127
AhnakAHNAK nucleoprotein0.103
Itpr1inositol 1,4,5-triphosphate receptor, type 10.100
Tuba1ctubulin, alpha 1C0.096
Sub1SUB1 homolog (S. cerevisiae)0.094
Plp2proteolipid protein 2 (colonic epithelium-enriched)0.090
Timp1TIMP metallopeptidase inhibitor 10.085
Gstm1glutathione S-transferase mu 10.084
Cdc42cell division cycle 42 (GTP binding protein)0.080
Ppiapeptidylprolyl isomerase A (cyclophilin A)0.080
Cnga1cyclic nucleotide gated channel alpha 10.077
Cstbcystatin B (stefin B)0.067
Txn1thioredoxin 10.060
Calm2calmodulin 20.060
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.057
Plp1proteolipid protein 10.051
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.048
Tmsb4xthymosin beta 4, X-linked0.048
Mgpmatrix Gla protein0.046
Vimvimentin0.041
Slc14a2solute carrier family 14 (urea transporter), member 20.037
Snap25synaptosomal-associated protein 250.035
Mbpmyelin basic protein0.033
Ank2ankyrin 2, neuronal0.033
Itga7integrin, alpha 70.033
Prkar1aprotein kinase, cAMP-dependent, regulatory, type I, alpha0.030
Pf4platelet factor 40.030
Myl6lmyosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like0.030
Atp1a2ATPase, Na+/K+ transporting, alpha 2 polypeptide0.029
Mep1ameprin 1 alpha0.029
Prdm2PR domain containing 2, with ZNF domain0.027
Sh3bgrSH3 domain binding glutamic acid-rich protein0.027
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.027
Pja2praja 2, RING-H2 motif containing0.027
Andproandrogen regulated protein0.026
Sncgsynuclein, gamma (breast cancer-specific protein 1)0.026
Nptnneuroplastin0.025
Gpx8glutathione peroxidase 80.025
Aqp4aquaporin 40.024
S100bS100 calcium binding protein B0.024
Ly6blymphocyte antigen 6 complex, locus B0.024
Aldocaldolase C, fructose-bisphosphate0.024
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.022
Asphaspartate-beta-hydroxylase0.022
Fxyd1FXYD domain-containing ion transport regulator 10.021
Gucy1b3guanylate cyclase 1, soluble, beta 30.021
Ptprdprotein tyrosine phosphatase, receptor type, D0.021
Padi2peptidyl arginine deiminase, type II0.021
Fkbp1aFK506 binding protein 1a0.020
Nexnnexilin (F actin binding protein)0.020
Pde5aphosphodiesterase 5A, cGMP-specific0.020
Gstm5glutathione S-transferase, mu 50.020
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.020
Prnpprion protein0.019
Inpp4binositol polyphosphate-4-phosphatase, type II0.019
Camk2dcalcium/calmodulin-dependent protein kinase II delta0.019
Tsc2tuberous sclerosis 20.019
Map2k1mitogen activated protein kinase kinase 10.019
Thtyrosine hydroxylase0.018
Hsbp1heat shock factor binding protein 10.018
Mpp4membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)0.018
Ebf3early B-cell factor 30.018
Pfkmphosphofructokinase, muscle0.017
Nptxrneuronal pentraxin receptor0.017
Rap1bRAP1B, member of RAS oncogene family0.017
Emp3epithelial membrane protein 30.017
Slc15a2solute carrier family 15 (H+/peptide transporter), member 20.017
Atp6v1dATPase, H+ transporting, lysosomal V1 subunit D0.017
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.017
Magmyelin-associated glycoprotein0.017
Nr3c2nuclear receptor subfamily 3, group C, member 20.016
Pitpnaphosphatidylinositol transfer protein, alpha0.016
Trhr2thyrotropin releasing hormone receptor 20.016
Dlg2discs, large homolog 2 (Drosophila)0.016
MrgprfMAS-related GPR, member F0.016
Cltcclathrin, heavy chain (Hc)0.016
Ap2a2adaptor-related protein complex 2, alpha 2 subunit0.015
Tspan7tetraspanin 70.015
Cpecarboxypeptidase E0.015
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.015
Higd1aHIG1 hypoxia inducible domain family, member 1A0.014
Rab7aRAB7A, member RAS oncogene family0.014
Scn1bsodium channel, voltage-gated, type I, beta0.014
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism