The network for 'hemostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms


The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.

NameDescriptionProbabilityFunc Analog Organism
C1QAcomplement component 1, q subcomponent, A chain0.995
ACTBactin, beta0.985
FLNAfilamin A, alpha0.983
TEKTEK tyrosine kinase, endothelial0.982
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.979
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.968
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.962
CAV1caveolin 1, caveolae protein, 22kDa0.953
SH3BP2SH3-domain binding protein 20.941
AXLAXL receptor tyrosine kinase0.939
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.939
FGAfibrinogen alpha chain0.935
RARAretinoic acid receptor, alpha0.927
LATlinker for activation of T cells0.917
TAL1T-cell acute lymphocytic leukemia 10.895
FN1fibronectin 10.889
VCAM1vascular cell adhesion molecule 10.884
MYH9myosin, heavy chain 9, non-muscle0.826
HBA2hemoglobin, alpha 20.738
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.701
NRP1neuropilin 10.680
TLN1talin 10.678
METmet proto-oncogene (hepatocyte growth factor receptor)0.666
CRPC-reactive protein, pentraxin-related0.655
C1QBcomplement component 1, q subcomponent, B chain0.614
PF4platelet factor 40.553
CDH5cadherin 5, type 2 (vascular endothelium)0.545
SYKspleen tyrosine kinase0.537
MPEG1macrophage expressed 10.530
PCYT2phosphate cytidylyltransferase 2, ethanolamine0.525
GP1BAglycoprotein Ib (platelet), alpha polypeptide0.524
BAG3BCL2-associated athanogene 30.516
PRKCAprotein kinase C, alpha0.510
CXCL2chemokine (C-X-C motif) ligand 20.500
F13A1coagulation factor XIII, A1 polypeptide0.497
PLCG1phospholipase C, gamma 10.495
FGBfibrinogen beta chain0.464
CXCL9chemokine (C-X-C motif) ligand 90.456
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.435
POU5F1POU class 5 homeobox 10.429
PLAUplasminogen activator, urokinase0.418
FYBFYN binding protein0.400
ACTA2actin, alpha 2, smooth muscle, aorta0.386
NCF1neutrophil cytosolic factor 10.377
EGFRepidermal growth factor receptor0.370
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.369
C1QCcomplement component 1, q subcomponent, C chain0.362
CXCL10chemokine (C-X-C motif) ligand 100.361
PTRFpolymerase I and transcript release factor0.359
COL4A2collagen, type IV, alpha 20.359
PTGISprostaglandin I2 (prostacyclin) synthase0.348
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.326
CXCL5chemokine (C-X-C motif) ligand 50.323
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.318
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.315
PLATplasminogen activator, tissue0.315
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.305
CFL1cofilin 1 (non-muscle)0.300
BLOC1S1biogenesis of lysosomal organelles complex-1, subunit 10.295
ARRB1arrestin, beta 10.295
HBG2hemoglobin, gamma G0.294
MYL6myosin, light chain 6, alkali, smooth muscle and non-muscle0.293
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.291
GAS6growth arrest-specific 60.290
MED25mediator complex subunit 250.288
FYNFYN oncogene related to SRC, FGR, YES0.288
COL4A1collagen, type IV, alpha 10.281
MYH11myosin, heavy chain 11, smooth muscle0.281
CD93CD93 molecule0.273
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.268
SNAP25synaptosomal-associated protein, 25kDa0.267
HSPB7heat shock 27kDa protein family, member 7 (cardiovascular)0.266
MASP2mannan-binding lectin serine peptidase 20.266
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.265
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.243
STAB1stabilin 10.227
VAV1vav 1 guanine nucleotide exchange factor0.224
ANXA1annexin A10.223
MYL12Bmyosin, light chain 12B, regulatory0.221
CCR2chemokine (C-C motif) receptor 20.218
LGALS1lectin, galactoside-binding, soluble, 10.204
SMN1survival of motor neuron 1, telomeric0.199
TBXA2Rthromboxane A2 receptor0.198
NR2F2nuclear receptor subfamily 2, group F, member 20.197
BLOC1S2biogenesis of lysosomal organelles complex-1, subunit 20.195
VAMP3vesicle-associated membrane protein 3 (cellubrevin)0.193
SHC2SHC (Src homology 2 domain containing) transforming protein 20.188
CD163CD163 molecule0.188
TICAM2toll-like receptor adaptor molecule 20.188
SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 10.186
NR0B2nuclear receptor subfamily 0, group B, member 20.186
S100A10S100 calcium binding protein A100.185
F2coagulation factor II (thrombin)0.180
DARCDuffy blood group, chemokine receptor0.178
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pdgfaaplatelet-derived growth factor alpha a0.813
fggfibrinogen, gamma polypeptide0.648
fgafibrinogen alpha chain0.475
ambplalpha-1-microglobulin/bikunin precursor, like0.449
foxa1forkhead box A10.418
col11a1acollagen, type XI, alpha 1a0.259
dag1dystroglycan 10.256
vtnbvitronectin b0.235
fn1bfibronectin 1b0.197
lamb1alaminin, beta 1a0.185
tagln2transgelin 20.162
c9complement component 90.136
gipgastric inhibitory polypeptide0.126
slc20a1asolute carrier family 20, member 1a0.103
nr1h5nuclear receptor subfamily 1, group H, member 50.092
krt8keratin 80.083
f5coagulation factor V0.082
itih2inter-alpha (globulin) inhibitor H20.081
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.079
cfbcomplement factor B0.077
wlswntless homolog (Drosophila)0.069
rhdRh blood group, D antigen0.067
fgbfibrinogen, B beta polypeptide0.064
mpllmyeloproliferative leukemia virus oncogene, like0.063
sult2st1sulfotransferase family 2, cytosolic sulfotransferase 10.062
foxe1forkhead box E1 (thyroid transcription factor 2)0.060
surf4lsurfeit gene 4, like0.056
gna13aguanine nucleotide binding protein (G protein), alpha 13a0.055
hmcn1hemicentin 10.054
mst1macrophage stimulating 1 (hepatocyte growth factor-like)0.053
klfdKruppel-like factor d0.053
ef1aelongation factor 1-alpha0.052
itga2bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)0.050
hs6st2heparan sulfate 6-O-sulfotransferase 20.050
bmp2abone morphogenetic protein 2a0.049
sparcsecreted acidic cysteine rich glycoprotein0.046
apomapolipoprotein M0.046
cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.045
mesp2mesoderm posterior 2 homolog (mouse)0.045
col4a3collagen, type IV, alpha 30.043
col17a1acollagen, type XVII, alpha 1a0.043
LOC100003514protein kinase C alpha type-like0.042
lrrc15leucine rich repeat containing 150.041
rykreceptor-like tyrosine kinase0.039
hao1hydroxyacid oxidase (glycolate oxidase) 10.039
apoc2apolipoprotein C-II0.038
anxa11bannexin A11b0.038
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.037
col4a1collagen, type IV, alpha 10.036
pdlim1PDZ and LIM domain 1 (elfin)0.036
sdc2syndecan 20.034
sulf2lsulfatase 2, like0.033
nkx2.3NK2 transcription factor related 30.033
msxdmuscle segment homeobox D0.033
cpa5carboxypeptidase A50.031
csrnp1bcysteine-serine-rich nuclear protein 1b0.031
clec14aC-type lectin domain family 14, member A0.030
serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.030
krt18keratin 180.029
jag1bjagged 1b0.029
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.028
bfbcomplement component bfb0.028
col1a1acollagen, type I, alpha 1a0.027
fibplfibroblast growth factor (acidic) intracellular binding protein, like0.027
rnasel1ribonuclease like 10.027
igfbp7insulin-like growth factor binding protein 70.027
LOC796447hypothetical protein LOC7964470.026
rbp2bretinol binding protein 2b, cellular0.025
sec24dSEC24 family, member D (S. cerevisiae)0.025
aldh8a1aldehyde dehydrogenase 8 family, member A10.025
cfl2lcofilin 2, like0.022
ntn4netrin 40.022
dpyddihydropyrimidine dehydrogenase0.022
msxamuscle segment homeobox A0.022
mmp9matrix metalloproteinase 90.022
actn1actinin, alpha 10.022
dnmt4DNA (cytosine-5-)-methyltransferase 40.021
serpind1serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 10.021
yap1Yes-associated protein 10.020
vaspvasodilator-stimulated phosphoprotein0.020
runx1runt-related transcription factor 10.019
tlr8btoll-like receptor 8b0.019
camk2g1calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 10.018
cyp24a1cytochrome P450, family 24, subfamily A, polypeptide 10.018
gstalglutathione S-transferase, alpha-like0.018
itgb3bintegrin beta 3b0.018
anxa1aannexin A1a0.017
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Lcp3Larval cuticle protein 30.058
Cpr49AeCuticular protein 49Ae0.025
proPO-A1prophenol oxidase A10.018
CG8193CG8193 gene product from transcript CG8193-RA0.017
Spn28DSerpin 28D0.015
CG15080CG15080 gene product from transcript CG15080-RA0.014
Cpr67Fa1Cuticular protein 67Fa10.013
CG15515CG15515 gene product from transcript CG15515-RA0.013
Lcp4Larval cuticle protein 40.013
Lcp65AcCG6956 gene product from transcript CG6956-RA0.013
Lcp2Larval cuticle protein 20.011
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Hps1Hermansky-Pudlak syndrome 1 homolog (human)0.980
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.952
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.934
AxlAXL receptor tyrosine kinase0.913
Prkceprotein kinase C, epsilon0.886
Ptgs2prostaglandin-endoperoxide synthase 20.886
Ilkintegrin linked kinase0.870
Cficomplement component factor i0.844
Ap3b1adaptor-related protein complex 3, beta 1 subunit0.840
Ceacam2carcinoembryonic antigen-related cell adhesion molecule 20.821
F2coagulation factor II0.790
Hps6Hermansky-Pudlak syndrome 60.783
C3complement component 30.783
Fzd8frizzled homolog 8 (Drosophila)0.775
Rab27aRAB27A, member RAS oncogene family0.773
Hps5Hermansky-Pudlak syndrome 5 homolog (human)0.766
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.747
Ldb3LIM domain binding 30.739
Lyl1lymphoblastomic leukemia 10.726
Gp5glycoprotein 5 (platelet)0.714
Vhlvon Hippel-Lindau tumor suppressor0.707
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.688
Fggfibrinogen gamma chain0.682
P2rx1purinergic receptor P2X, ligand-gated ion channel, 10.682
Itgb1integrin beta 1 (fibronectin receptor beta)0.677
Lystlysosomal trafficking regulator0.657
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.648
Cnn2calponin 20.644
WasWiskott-Aldrich syndrome homolog (human)0.630
LOC100503041PDZ domain-containing protein 7-like0.624
Plauplasminogen activator, urokinase0.614
Apoa1apolipoprotein A-I0.611
Prkcdprotein kinase C, delta0.599
Itgb3integrin beta 30.596
Mertkc-mer proto-oncogene tyrosine kinase0.594
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.568
Alox5aparachidonate 5-lipoxygenase activating protein0.555
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.531
Cd22CD22 antigen0.529
Saa4serum amyloid A 40.510
Myo1cmyosin IC0.505
Ptpn6protein tyrosine phosphatase, non-receptor type 60.502
Timp2tissue inhibitor of metalloproteinase 20.481
S1pr2sphingosine-1-phosphate receptor 20.478
Dlg4discs, large homolog 4 (Drosophila)0.476
Nfe2l2nuclear factor, erythroid derived 2, like 20.474
Sirpasignal-regulatory protein alpha0.469
Rxraretinoid X receptor alpha0.463
Nf1neurofibromatosis 10.461
Pzppregnancy zone protein0.459
Nos3nitric oxide synthase 3, endothelial cell0.454
FasFas (TNF receptor superfamily member 6)0.446
Ppargperoxisome proliferator activated receptor gamma0.441
Ptprcprotein tyrosine phosphatase, receptor type, C0.430
Apoa5apolipoprotein A-V0.425
Fcgr3Fc receptor, IgG, low affinity III0.419
Gp9glycoprotein 9 (platelet)0.414
Hgfachepatocyte growth factor activator0.412
Vdrvitamin D receptor0.407
Mrvi1MRV integration site 10.404
Leprleptin receptor0.400
FybFYN binding protein0.399
Tln1talin 10.392
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.388
Smad4MAD homolog 4 (Drosophila)0.383
Ighimmunoglobulin heavy chain complex0.374
Adra2cadrenergic receptor, alpha 2c0.368
S100a11S100 calcium binding protein A11 (calgizzarin)0.366
Ush1gUsher syndrome 1G homolog (human)0.365
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.354
Gata1GATA binding protein 10.354
Vav1vav 1 oncogene0.352
Gcgrglucagon receptor0.345
Ambpalpha 1 microglobulin/bikunin0.341
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.340
Itga2bintegrin alpha 2b0.335
Serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.333
Mplmyeloproliferative leukemia virus oncogene0.333
Nr3c1nuclear receptor subfamily 3, group C, member 10.332
Anxa4annexin A40.330
Cav1caveolin 1, caveolae protein0.327
BtkBruton agammaglobulinemia tyrosine kinase0.327
Pou2af1POU domain, class 2, associating factor 10.325
Ncoa3nuclear receptor coactivator 30.324
Lmnalamin A0.319
1300017J02RikRIKEN cDNA 1300017J02 gene0.318
Lhx1LIM homeobox protein 10.314
Ptprjprotein tyrosine phosphatase, receptor type, J0.310
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.307
Nos2nitric oxide synthase 2, inducible0.306
Latlinker for activation of T cells0.302
Plcd1phospholipase C, delta 10.299
Wnt3awingless-related MMTV integration site 3A0.287
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
AhnakAHNAK nucleoprotein0.611
Anxa1annexin A10.574
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.471
Itgb1integrin, beta 10.451
Gcgroup specific component0.257
Pzppregnancy-zone protein0.256
S100a6S100 calcium binding protein A60.236
C1scomplement component 1, s subcomponent0.212
Anxa5annexin A50.177
B2mbeta-2 microglobulin0.151
Cd151CD151 molecule (Raph blood group)0.142
Cfbcomplement factor B0.119
C9complement component 90.110
Tagln2transgelin 20.097
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.097
Capn2calpain 20.083
Itih4inter alpha-trypsin inhibitor, heavy chain 40.070
Ptafrplatelet-activating factor receptor0.070
Clec4fC-type lectin domain family 4, member f0.066
Serpinf2serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 20.063
S100a10S100 calcium binding protein A100.063
Actbactin, beta0.061
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.057
Cma1chymase 1, mast cell0.057
Ctsccathepsin C0.057
C1rcomplement component 1, r subcomponent0.055
Cficomplement factor I0.055
Ifitm3interferon induced transmembrane protein 30.053
Plp2proteolipid protein 2 (colonic epithelium-enriched)0.051
Cd44Cd44 molecule0.050
Lmnalamin A0.049
Tpm3tropomyosin 3, gamma0.049
Stx1asyntaxin 1A (brain)0.048
Azgp1alpha-2-glycoprotein 1, zinc-binding0.048
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.046
Ctsbcathepsin B0.043
C4bcomplement component 4B (Chido blood group)0.043
Txnipthioredoxin interacting protein0.043
Cd63Cd63 molecule0.043
Flnafilamin A, alpha0.042
Map3k8mitogen-activated protein kinase kinase kinase 80.042
Agtr1aangiotensin II receptor, type 1a0.041
Cpb2carboxypeptidase B2 (plasma)0.040
Il1r1interleukin 1 receptor, type I0.037
S100a4S100 calcium-binding protein A40.036
Icam1intercellular adhesion molecule 10.035
Rhoaras homolog gene family, member A0.035
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.035
Ctsl1cathepsin L10.035
Agxt2alanine-glyoxylate aminotransferase 20.035
Myadmmyeloid-associated differentiation marker0.034
Cnn3calponin 3, acidic0.034
Myo1emyosin IE0.033
Aqp9aquaporin 90.033
Platplasminogen activator, tissue0.033
Ltbp1latent transforming growth factor beta binding protein 10.033
Ramp1receptor (G protein-coupled) activity modifying protein 10.032
LOC293989cytochrome P450-like0.032
C5ar1complement component 5a receptor 10.031
S1pr2sphingosine-1-phosphate receptor 20.031
Otcornithine carbamoyltransferase0.031
Spink1serine peptidase inhibitor, Kazal type 10.030
Inpp5dinositol polyphosphate-5-phosphatase D0.030
Serpinb6aserine (or cysteine) peptidase inhibitor, clade B, member 6a0.030
Hckhemopoietic cell kinase0.030
Pla1aphospholipase A1 member A0.030
Cr1lcomplement component (3b/4b) receptor 1-like0.029
Aebp1AE binding protein 10.029
RGD1307396similar to RIKEN cDNA 6330406I150.028
Prelpproline/arginine-rich end leucine-rich repeat protein0.028
Tpm4tropomyosin 40.028
C8bcomplement component 8, beta polypeptide0.028
Mbl2mannose-binding lectin (protein C) 20.028
TekTEK tyrosine kinase, endothelial0.027
Csrp1cysteine and glycine-rich protein 10.027
Fabp1fatty acid binding protein 1, liver0.027
Duoxa1dual oxidase maturation factor 10.027
Slco2b1solute carrier organic anion transporter family, member 2b10.027
Ccl4chemokine (C-C motif) ligand 40.026
KitlgKIT ligand0.026
Klhl6kelch-like 6 (Drosophila)0.026
Lhfplipoma HMGIC fusion partner0.026
MdficMyoD family inhibitor domain containing0.026
Rab3il1RAB3A interacting protein (rabin3)-like 10.026
Zfp36l1zinc finger protein 36, C3H type-like 10.026
C1galt1core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 10.025
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.025
Serpina11serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 110.025
Hdchistidine decarboxylase0.024
Evi2aecotropic viral integration site 2A0.024
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.024
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism