The network for 'positive regulation of tor signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of tor signaling

Any process that activates or increases the frequency, rate or extent of TOR signaling.

NameDescriptionProbabilityFunc Analog Organism
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 11.000
MTORmechanistic target of rapamycin (serine/threonine kinase)1.000
RRAGCRas-related GTP binding C1.000
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.999
RPTORregulatory associated protein of MTOR, complex 10.977
AKT1S1AKT1 substrate 1 (proline-rich)0.901
MAP3K11mitogen-activated protein kinase kinase kinase 110.843
RRAGARas-related GTP binding A0.825
C7orf59chromosome 7 open reading frame 590.720
LAMTOR3late endosomal/lysosomal adaptor, MAPK and MTOR activator 30.658
MAPKAP1mitogen-activated protein kinase associated protein 10.637
RRAGDRas-related GTP binding D0.630
DEPTORDEP domain containing MTOR-interacting protein0.599
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.579
HBXIPhepatitis B virus x interacting protein0.536
PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 10.471
AXLAXL receptor tyrosine kinase0.437
AKT1v-akt murine thymoma viral oncogene homolog 10.437
PRR5proline rich 5 (renal)0.356
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.323
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.101
UBL5ubiquitin-like 50.098
ABCF3ATP-binding cassette, sub-family F (GCN20), member 30.089
CCNT2cyclin T20.080
RHEBRas homolog enriched in brain0.076
TELO2TEL2, telomere maintenance 2, homolog (S. cerevisiae)0.055
SOS1son of sevenless homolog 1 (Drosophila)0.050
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.045
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.044
SOCS5suppressor of cytokine signaling 50.043
TRAF2TNF receptor-associated factor 20.040
PRR5Lproline rich 5 like0.035
RHEBL1Ras homolog enriched in brain like 10.034
RABIFRAB interacting factor0.029
ARHGAP5Rho GTPase activating protein 50.027
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.026
UBR1ubiquitin protein ligase E3 component n-recognin 10.024
SH3RF1SH3 domain containing ring finger 10.021
FKBP1AFK506 binding protein 1A, 12kDa0.019
ATP6V1G1ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G10.019
EIF4Eeukaryotic translation initiation factor 4E0.017
SIRT1sirtuin 10.016
TMEM160transmembrane protein 1600.015
RICTORRPTOR independent companion of MTOR, complex 20.014
BAG1BCL2-associated athanogene0.014
MAP2K1mitogen-activated protein kinase kinase 10.014
NDUFA13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.014
CSNK1G3casein kinase 1, gamma 30.013
C7orf25chromosome 7 open reading frame 250.013
LARSleucyl-tRNA synthetase0.013
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.012
FAM18B1family with sequence similarity 18, member B10.012
MAP4K3mitogen-activated protein kinase kinase kinase kinase 30.012
ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E10.011
CAPN7calpain 70.010
RAB9ARAB9A, member RAS oncogene family0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.818
RagACG11968 gene product from transcript CG11968-RA0.764
Atg6Autophagy-specific gene 60.313
CG1347CG1347 gene product from transcript CG1347-RB0.169
S6kRPS6-p70-protein kinase0.154
slikSterile20-like kinase0.125
Rab-RP4Rab-related protein 40.115
raptorCG4320 gene product from transcript CG4320-RA0.112
CG13603CG13603 gene product from transcript CG13603-RA0.102
CG6272CG6272 gene product from transcript CG6272-RA0.071
picoCG11940 gene product from transcript CG11940-RA0.063
Atg8aAutophagy-specific gene 8a0.058
vps2CG14542 gene product from transcript CG14542-RA0.051
RalaRas-related protein0.044
chicoCG5686 gene product from transcript CG5686-RB0.044
maskmultiple ankyrin repeats single KH domain0.043
Chmp1CG4108 gene product from transcript CG4108-RA0.042
CG12384CG12384 gene product from transcript CG12384-RA0.042
CG15012CG15012 gene product from transcript CG15012-RB0.039
CG6852CG6852 gene product from transcript CG6852-RB0.038
Atg7Autophagy-specific gene 70.037
RagCCG8707 gene product from transcript CG8707-RA0.037
RanBPMRan-binding protein M0.036
Ank2Ankyrin 20.036
MTF-1Metal response element-binding Transcription Factor-10.035
ninaEneither inactivation nor afterpotential E0.032
RhebCG1081 gene product from transcript CG1081-RA0.030
Atg1Autophagy-specific gene 10.030
Elongin-CElongin C0.029
eIF2B-alphaCG7883 gene product from transcript CG7883-RA0.027
Pi3K59FPhosphotidylinositol 3 kinase 59F0.026
Atg12Autophagy-specific gene 120.025
CG3837CG3837 gene product from transcript CG3837-RA0.024
VhaM9.7-1CG11589 gene product from transcript CG11589-RA0.022
CG5110CG5110 gene product from transcript CG5110-RA0.021
Pk61CProtein kinase 61C0.019
Atg4Autophagy-specific gene 40.018
upd2unpaired 20.018
CG3566CG3566 gene product from transcript CG3566-RB0.016
maf-SCG9954 gene product from transcript CG9954-RA0.016
CG10673CG10673 gene product from transcript CG10673-RA0.015
ThorCG8846 gene product from transcript CG8846-RA0.015
CG14931CG14931 gene product from transcript CG14931-RB0.014
CG6191CG6191 gene product from transcript CG6191-RA0.014
CG5161CG5161 gene product from transcript CG5161-RA0.013
AGO2Argonaute 20.013
ird1immune response deficient 10.012
Ilp6Insulin-like peptide 60.012
CG12868CG12868 gene product from transcript CG12868-RB0.012
vps24Charged multivesicular body protein 30.012
CHMP2BCharged multivesicular body protein 2b0.011
CG42863CG42863 gene product from transcript CG42863-RB0.011
Sin1SAPK-interacting protein 10.011
bossbride of sevenless0.011
ns3nucleostemin 30.011
EndoGIEndonuclease G inhibitor0.011
CG14104CG14104 gene product from transcript CG14104-RB0.010
Nedd4CG42279 gene product from transcript CG42279-RJ0.010
Axud1CG4272 gene product from transcript CG4272-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mtormechanistic target of rapamycin (serine/threonine kinase)1.000
RictorRPTOR independent companion of MTOR, complex 20.978
Mlst8MTOR associated protein, LST8 homolog (S. cerevisiae)0.571
Mapkap1mitogen-activated protein kinase associated protein 10.330
RoraRAR-related orphan receptor alpha0.259
Kitlkit ligand0.159
Hes1hairy and enhancer of split 1 (Drosophila)0.124
Fnip1folliculin interacting protein 10.124
Mpp5membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)0.101
BlnkB-cell linker0.096
Lrp8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor0.090
Vapavesicle-associated membrane protein, associated protein A0.069
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.061
Ypel3yippee-like 3 (Drosophila)0.060
Nr2e1nuclear receptor subfamily 2, group E, member 10.053
Telo2TEL2, telomere maintenance 2, homolog (S. cerevisiae)0.048
Abtb1ankyrin repeat and BTB (POZ) domain containing 10.045
Nfat5nuclear factor of activated T-cells 50.042
BrafBraf transforming gene0.042
Fcho1FCH domain only 10.041
Dab1disabled homolog 1 (Drosophila)0.041
Rptorregulatory associated protein of MTOR, complex 10.040
Arhgap9Rho GTPase activating protein 90.039
Tbc1d17TBC1 domain family, member 170.038
Bcl2B-cell leukemia/lymphoma 20.034
Crklv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.033
Wdr45WD repeat domain 450.032
Kitkit oncogene0.032
Npc1Niemann Pick type C10.031
Inpp5kinositol polyphosphate 5-phosphatase K0.031
Ezh1enhancer of zeste homolog 1 (Drosophila)0.029
Dyrk1adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a0.027
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.026
Rasgrp2RAS, guanyl releasing protein 20.026
Rab5aRAB5A, member RAS oncogene family0.026
Stat5bsignal transducer and activator of transcription 5B0.025
Fbxo11F-box protein 110.025
Nrbp2nuclear receptor binding protein 20.023
Cd2CD2 antigen0.023
Slc27a1solute carrier family 27 (fatty acid transporter), member 10.022
Ghrgrowth hormone receptor0.022
Clcn6chloride channel 60.022
Abca2ATP-binding cassette, sub-family A (ABC1), member 20.022
1700081L11RikRIKEN cDNA 1700081L11 gene0.022
Myo6myosin VI0.021
Mtmr3myotubularin related protein 30.021
Atp2a3ATPase, Ca++ transporting, ubiquitous0.021
Cdk5cyclin-dependent kinase 50.021
Mettl17methyltransferase like 170.021
Tefthyrotroph embryonic factor0.021
Akap10A kinase (PRKA) anchor protein 100.020
Sh2d3cSH2 domain containing 3C0.020
Tjp1tight junction protein 10.020
Uap1UDP-N-acetylglucosamine pyrophosphorylase 10.019
Rab1RAB1, member RAS oncogene family0.019
Mier1mesoderm induction early response 1 homolog (Xenopus laevis0.019
Plcg2phospholipase C, gamma 20.019
Cnnm3cyclin M30.019
Tnfrsf18tumor necrosis factor receptor superfamily, member 180.018
Ulk1Unc-51 like kinase 1 (C. elegans)0.018
Ahraryl-hydrocarbon receptor0.018
Clk4CDC like kinase 40.018
Gucy1b3guanylate cyclase 1, soluble, beta 30.017
Cyfip2cytoplasmic FMR1 interacting protein 20.017
Spns1spinster homolog 1 (Drosophila)0.017
Nfyanuclear transcription factor-Y alpha0.017
Slc25a38solute carrier family 25, member 380.017
Prkaa1protein kinase, AMP-activated, alpha 1 catalytic subunit0.016
Rab5bRAB5B, member RAS oncogene family0.016
Hipk1homeodomain interacting protein kinase 10.016
Zfp358zinc finger protein 3580.016
Jmyjunction-mediating and regulatory protein0.016
Rgs11regulator of G-protein signaling 110.016
Usp32ubiquitin specific peptidase 320.016
Dgkediacylglycerol kinase, epsilon0.016
Cadps2Ca2+-dependent activator protein for secretion 20.015
Nprl3nitrogen permease regulator-like 3 (S. cerevisiae)0.015
Icam2intercellular adhesion molecule 20.015
Phf1PHD finger protein 10.015
Ncoa2nuclear receptor coactivator 20.015
Mgrn1mahogunin, ring finger 10.015
Smg6Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)0.015
Ip6k1inositol hexaphosphate kinase 10.015
Gja1gap junction protein, alpha 10.015
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.015
Sav1salvador homolog 1 (Drosophila)0.014
Lef1lymphoid enhancer binding factor 10.014
Dpp7dipeptidylpeptidase 70.014
Eif2ak3eukaryotic translation initiation factor 2 alpha kinase 30.014
Scyl1SCY1-like 1 (S. cerevisiae)0.014
Vps18vacuolar protein sorting 18 (yeast)0.014
Grap2GRB2-related adaptor protein 20.014
Arrdc1arrestin domain containing 10.014
Fam189bfamily with sequence similarity 189, member B0.014
Cdc42bpaCDC42 binding protein kinase alpha0.014
Pofut1protein O-fucosyltransferase 10.014
Jhdm1djumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)0.014
Ikbkginhibitor of kappaB kinase gamma0.014
Traf6TNF receptor-associated factor 60.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cdh5cadherin 50.078
Cyyr1cysteine/tyrosine-rich 10.060
Eltd1EGF, latrophilin and seven transmembrane domain containing 10.041
Zhx1zinc fingers and homeoboxes 10.039
Map3k7ip1mitogen-activated protein kinase kinase kinase 7 interacting protein 10.028
Depdc5DEP domain containing 50.024
Mmp16matrix metallopeptidase 160.024
Gng11guanine nucleotide binding protein (G protein), gamma 110.023
Coq10acoenzyme Q10 homolog A (S. cerevisiae)0.021
TekTEK tyrosine kinase, endothelial0.019
Stard8StAR-related lipid transfer (START) domain containing 80.019
Rasgrp3RAS guanyl releasing protein 3 (calcium and DAG-regulated)0.019
Kank3KN motif and ankyrin repeat domains 30.018
Prkd3protein kinase D30.018
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.018
Sh3bp5SH3-domain binding protein 5 (BTK-associated)0.016
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.016
Elk3ELK3, ETS-domain protein0.016
Tsen54tRNA splicing endonuclease 54 homolog (S. cerevisiae)0.015
Tmem204transmembrane protein 2040.015
Adnpactivity-dependent neuroprotector homeobox0.014
Mpdzmultiple PDZ domain protein0.014
Senp6SUMO1/sentrin specific peptidase 60.013
Cgnl1cingulin-like 10.013
Kidins220kinase D-interacting substrate 2200.012
Amigo1adhesion molecule with Ig like domain 10.012
Pde2aphosphodiesterase 2A, cGMP-stimulated0.012
Plxnd1plexin D10.011
Zmym2zinc finger, MYM-type 20.011
Raf1v-raf-leukemia viral oncogene 10.011
Angpt2angiopoietin 20.011
Sept4septin 40.010
Syne1spectrin repeat containing, nuclear envelope 10.010
Ptcd2pentatricopeptide repeat domain 20.010
Vezf1vascular endothelial zinc finger 10.010
Prkar1bprotein kinase, cAMP dependent regulatory, type I, beta0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism