The network for 'hippocampus development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hippocampus development

The progression of the hippocampus over time from its initial formation until its mature state.

NameDescriptionProbabilityFunc Analog Organism
HDAC1histone deacetylase 10.987
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.954
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.845
TSC2tuberous sclerosis 20.842
DLG4discs, large homolog 4 (Drosophila)0.766
RXRAretinoid X receptor, alpha0.720
BBS2Bardet-Biedl syndrome 20.685
USP46ubiquitin specific peptidase 460.620
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.613
CASP9caspase 9, apoptosis-related cysteine peptidase0.561
CDC27cell division cycle 27 homolog (S. cerevisiae)0.475
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.365
SCHIP1schwannomin interacting protein 10.352
NR4A1nuclear receptor subfamily 4, group A, member 10.333
APAF1apoptotic peptidase activating factor 10.298
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.246
NR4A2nuclear receptor subfamily 4, group A, member 20.235
BBS9Bardet-Biedl syndrome 90.227
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.188
MKL1megakaryoblastic leukemia (translocation) 10.187
RPL18Aribosomal protein L18a0.168
WWOXWW domain containing oxidoreductase0.162
XIAPX-linked inhibitor of apoptosis0.159
GSK3Bglycogen synthase kinase 3 beta0.145
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.138
SKIv-ski sarcoma viral oncogene homolog (avian)0.130
DCTN1dynactin 10.122
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.117
DLGAP1discs, large (Drosophila) homolog-associated protein 10.116
HNF4Ahepatocyte nuclear factor 4, alpha0.107
AXIN1axin 10.104
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.095
CREBBPCREB binding protein0.093
SCRIBscribbled homolog (Drosophila)0.093
ALKanaplastic lymphoma receptor tyrosine kinase0.092
MED25mediator complex subunit 250.090
LRP6low density lipoprotein receptor-related protein 60.088
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.088
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.085
NCOR2nuclear receptor corepressor 20.083
CDK5cyclin-dependent kinase 50.082
GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.081
EGR1early growth response 10.080
ZHX1zinc fingers and homeoboxes 10.078
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.077
PCM1pericentriolar material 10.076
SPRR2Asmall proline-rich protein 2A0.074
SGK3serum/glucocorticoid regulated kinase family, member 30.074
KDM6Alysine (K)-specific demethylase 6A0.074
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.074
NEDD9neural precursor cell expressed, developmentally down-regulated 90.073
MYOGmyogenin (myogenic factor 4)0.072
SIN3ASIN3 homolog A, transcription regulator (yeast)0.072
FOSFBJ murine osteosarcoma viral oncogene homolog0.070
MYOD1myogenic differentiation 10.070
HDAC2histone deacetylase 20.070
PAX8paired box 80.068
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.065
WDR48WD repeat domain 480.064
EGR3early growth response 30.063
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.063
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.062
CLIP1CAP-GLY domain containing linker protein 10.061
USP12ubiquitin specific peptidase 120.061
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.059
SPOPspeckle-type POZ protein0.058
HDAC3histone deacetylase 30.057
PDX1pancreatic and duodenal homeobox 10.053
MKL2MKL/myocardin-like 20.052
QKIquaking homolog, KH domain RNA binding (mouse)0.051
CNOT6LCCR4-NOT transcription complex, subunit 6-like0.051
FEZ1fasciculation and elongation protein zeta 1 (zygin I)0.051
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 10.050
NLGN1neuroligin 10.050
LAMA4laminin, alpha 40.049
NR5A2nuclear receptor subfamily 5, group A, member 20.049
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.048
CABLES1Cdk5 and Abl enzyme substrate 10.047
NPEPPSaminopeptidase puromycin sensitive0.047
PDE4Dphosphodiesterase 4D, cAMP-specific0.046
BBS1Bardet-Biedl syndrome 10.046
UBR1ubiquitin protein ligase E3 component n-recognin 10.044
PPARAperoxisome proliferator-activated receptor alpha0.042
ARL4DADP-ribosylation factor-like 4D0.042
BAI1brain-specific angiogenesis inhibitor 10.042
EGR2early growth response 20.041
TCF4transcription factor 40.041
LHX3LIM homeobox 30.040
PNKPpolynucleotide kinase 3'-phosphatase0.040
YAP1Yes-associated protein 10.039
DEAF1deformed epidermal autoregulatory factor 1 (Drosophila)0.038
WDR20WD repeat domain 200.038
STK36serine/threonine kinase 360.037
MAP2K4mitogen-activated protein kinase kinase 40.037
BCL6B-cell CLL/lymphoma 60.036
BIRC2baculoviral IAP repeat containing 20.036
SIX3SIX homeobox 30.035
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Otx2orthodenticle homolog 2 (Drosophila)1.000
Shhsonic hedgehog1.000
Emx1empty spiracles homolog 1 (Drosophila)0.999
Pax6paired box gene 60.997
Pax2paired box gene 20.997
Gli3GLI-Kruppel family member GLI30.996
Dab1disabled homolog 1 (Drosophila)0.989
Pax3paired box gene 30.988
Lhx1LIM homeobox protein 10.972
Rargretinoic acid receptor, gamma0.971
Lef1lymphoid enhancer binding factor 10.971
Sox2SRY-box containing gene 20.970
Ctnnb1catenin (cadherin associated protein), beta 10.970
Ascl1achaete-scute complex homolog 1 (Drosophila)0.965
Fgf10fibroblast growth factor 100.950
Msx1homeobox, msh-like 10.942
Fgf8fibroblast growth factor 80.938
Gli2GLI-Kruppel family member GLI20.935
Dlx5distal-less homeobox 50.923
Bbs4Bardet-Biedl syndrome 4 (human)0.915
Lmx1bLIM homeobox transcription factor 1 beta0.903
Foxg1forkhead box G10.890
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.884
Fgfr1fibroblast growth factor receptor 10.883
Foxc2forkhead box C20.877
Foxc1forkhead box C10.876
Adrb1adrenergic receptor, beta 10.876
Sox9SRY-box containing gene 90.870
Neurod1neurogenic differentiation 10.848
Trp63transformation related protein 630.835
Lhx5LIM homeobox protein 50.827
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.816
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.811
Fgfr2fibroblast growth factor receptor 20.802
Efnb2ephrin B20.800
Emx2empty spiracles homolog 2 (Drosophila)0.798
Hoxd13homeobox D130.794
Isl1ISL1 transcription factor, LIM/homeodomain0.778
Pou3f3POU domain, class 3, transcription factor 30.776
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.773
Hand2heart and neural crest derivatives expressed transcript 20.771
Gscgoosecoid homeobox0.763
Rspo2R-spondin 2 homolog (Xenopus laevis)0.759
Hes5hairy and enhancer of split 5 (Drosophila)0.756
Prrx1paired related homeobox 10.756
Kiss1KiSS-1 metastasis-suppressor0.755
En1engrailed 10.754
Epha4Eph receptor A40.724
Tsc2tuberous sclerosis 20.717
Atoh7atonal homolog 7 (Drosophila)0.707
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.674
Dlx1distal-less homeobox 10.674
Retret proto-oncogene0.673
Tcfap2atranscription factor AP-2, alpha0.661
Sox3SRY-box containing gene 30.652
Hoxa1homeobox A10.638
Bmp7bone morphogenetic protein 70.635
Dlx2distal-less homeobox 20.634
Neurog3neurogenin 30.626
Hoxd11homeobox D110.622
Insm1insulinoma-associated 10.617
Gdnfglial cell line derived neurotrophic factor0.616
Hoxa13homeobox A130.606
Smosmoothened homolog (Drosophila)0.589
Bmp4bone morphogenetic protein 40.572
Wnt7awingless-related MMTV integration site 7A0.562
Pitx2paired-like homeodomain transcription factor 20.558
Zfpm2zinc finger protein, multitype 20.547
Twist2twist homolog 2 (Drosophila)0.541
Adra2badrenergic receptor, alpha 2b0.540
Gata4GATA binding protein 40.537
Shc3src homology 2 domain-containing transforming protein C30.514
Hdac2histone deacetylase 20.513
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.503
Wnt6wingless-related MMTV integration site 60.499
Dlx6distal-less homeobox 60.499
Hoxa10homeobox A100.494
Pou3f2POU domain, class 3, transcription factor 20.484
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.473
Hmx3H6 homeobox 30.462
Pbx1pre B-cell leukemia transcription factor 10.461
Pthlhparathyroid hormone-like peptide0.460
Ptk7PTK7 protein tyrosine kinase 70.459
Hes1hairy and enhancer of split 1 (Drosophila)0.456
Ephb2Eph receptor B20.455
Wnt3awingless-related MMTV integration site 3A0.452
Id1inhibitor of DNA binding 10.451
Tlx3T-cell leukemia, homeobox 30.449
Tbx1T-box 10.447
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.443
Lhx3LIM homeobox protein 30.441
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.440
Phox2bpaired-like homeobox 2b0.439
Trp53transformation related protein 530.438
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.434
Mmp24matrix metallopeptidase 240.430
Rarbretinoic acid receptor, beta0.430
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Lgals3lectin, galactoside-binding, soluble, 30.177
Tlr4toll-like receptor 40.103
Neurod2neurogenic differentiation 20.094
Dlg4discs, large homolog 4 (Drosophila)0.088
Nkx6-1NK6 homeobox 10.065
Nme1non-metastatic cells 1, protein (NM23A) expressed in0.064
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.064
S100a10S100 calcium binding protein A100.061
Npy5rneuropeptide Y receptor Y50.061
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.050
DbpD site of albumin promoter (albumin D-box) binding protein0.050
Nr5a2nuclear receptor subfamily 5, group A, member 20.046
Nr4a1nuclear receptor subfamily 4, group A, member 10.045
Lrrc7leucine rich repeat containing 70.044
Hoxa2homeo box A20.043
Aqp4aquaporin 40.040
Shank1SH3 and multiple ankyrin repeat domains 10.039
Anxa2annexin A20.039
S100a11S100 calcium binding protein A11 (calizzarin)0.038
Cckbrcholecystokinin B receptor0.038
Gabbr2gamma-aminobutyric acid (GABA) B receptor 20.038
Nr4a2nuclear receptor subfamily 4, group A, member 20.035
Chrm1cholinergic receptor, muscarinic 10.034
Ppiapeptidylprolyl isomerase A (cyclophilin A)0.034
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.033
Anxa5annexin A50.033
Egr3early growth response 30.033
Ppypancreatic polypeptide0.033
Adra2cadrenergic, alpha-2C-, receptor0.032
Casp2caspase 20.032
Pgam1phosphoglycerate mutase 1 (brain)0.031
Nat1N-acetyltransferase 10.031
Acrv1acrosomal vesicle protein 10.031
Nr1d2nuclear receptor subfamily 1, group D, member 20.030
Vcsa1variable coding sequence A10.030
Olr1493olfactory receptor gene Olr14930.029
Casp3caspase 30.028
Cr1lcomplement component (3b/4b) receptor 1-like0.028
S100a6S100 calcium binding protein A60.028
Mll5myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)0.028
Myo1dmyosin ID0.028
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.027
Nr1h4nuclear receptor subfamily 1, group H, member 40.027
Gja4gap junction protein, alpha 40.027
Prdx2peroxiredoxin 20.027
Ptprcprotein tyrosine phosphatase, receptor type, C0.026
Gse1genetic suppressor element 10.026
Slc25a5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 50.025
Cd9CD9 molecule0.025
Trim29tripartite motif-containing 290.025
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.025
Jak1Janus kinase 10.025
Nr0b2nuclear receptor subfamily 0, group B, member 20.025
Actr2ARP2 actin-related protein 2 homolog (yeast)0.024
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.024
Mdh1malate dehydrogenase 1, NAD (soluble)0.024
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.024
Psmb5proteasome (prosome, macropain) subunit, beta type 50.024
Rup2urinary protein 20.023
Pou3f3POU class 3 homeobox 30.023
Ucp1uncoupling protein 1 (mitochondrial, proton carrier)0.023
Ptch1patched homolog 1 (Drosophila)0.023
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.023
Slc16a8solute carrier family 16, member 8 (monocarboxylic acid transporter 3)0.023
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.023
Ctsccathepsin C0.023
Galnt5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)0.023
Naaladl1N-acetylated alpha-linked acidic dipeptidase-like 10.023
Crhbpcorticotropin releasing hormone binding protein0.023
Arandrogen receptor0.022
Retnlaresistin like alpha0.022
Cnga2cyclic nucleotide gated channel alpha 20.022
Il12binterleukin 12B0.022
Casp7caspase 70.022
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.022
Dad1defender against cell death 10.022
Impg2interphotoreceptor matrix proteoglycan 20.022
Pompproteasome maturation protein0.021
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.021
Klk8kallikrein related-peptidase 80.021
Hrh2histamine receptor H 20.021
Camkk2calcium/calmodulin-dependent protein kinase kinase 2, beta0.021
Tnrtenascin R0.021
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.021
Csrnp2cysteine-serine-rich nuclear protein 20.020
Stx2syntaxin 20.020
Pou3f1POU class 3 homeobox 10.020
Cd36CD36 molecule (thrombospondin receptor)0.020
Svs1seminal vesicle secretory protein 10.020
Gria2glutamate receptor, ionotropic, AMPA 20.020
Ppardperoxisome proliferator-activated receptor delta0.020
Grik3glutamate receptor, ionotropic, kainate 30.020
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.020
Fgf7fibroblast growth factor 70.020
Arpc1bactin related protein 2/3 complex, subunit 1B0.020
Trpc4transient receptor potential cation channel, subfamily C, member 40.020
Dhfrdihydrofolate reductase0.020
Nrxn3neurexin 30.020
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism