The network for 'regulation of oxidative phosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of oxidative phosphorylation

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.

NameDescriptionProbabilityFunc Analog Organism
EIF3Keukaryotic translation initiation factor 3, subunit K0.267
PDZD11PDZ domain containing 110.220
TUFMTu translation elongation factor, mitochondrial0.146
EIF4A1eukaryotic translation initiation factor 4A10.120
APEX1APEX nuclease (multifunctional DNA repair enzyme) 10.108
PHBprohibitin0.093
YBX1Y box binding protein 10.089
AHCYadenosylhomocysteinase0.084
MRPL4mitochondrial ribosomal protein L40.080
C1QBPcomplement component 1, q subcomponent binding protein0.076
PTDSS1phosphatidylserine synthase 10.075
GRPEL1GrpE-like 1, mitochondrial (E. coli)0.055
HDAC1histone deacetylase 10.054
VDAC2voltage-dependent anion channel 20.052
TOMM22translocase of outer mitochondrial membrane 22 homolog (yeast)0.050
MRPS7mitochondrial ribosomal protein S70.045
TRAP1TNF receptor-associated protein 10.045
BIN1bridging integrator 10.043
EIF3Ieukaryotic translation initiation factor 3, subunit I0.041
POLR2Fpolymerase (RNA) II (DNA directed) polypeptide F0.041
ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.034
ENO1enolase 1, (alpha)0.030
PRMT1protein arginine methyltransferase 10.027
NME1-NME2NME1-NME2 readthrough0.027
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.026
MRPL12mitochondrial ribosomal protein L120.026
GPIglucose-6-phosphate isomerase0.025
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.025
CHD4chromodomain helicase DNA binding protein 40.024
AK2adenylate kinase 20.023
PABPC4poly(A) binding protein, cytoplasmic 4 (inducible form)0.022
IMPDH2IMP (inosine 5'-monophosphate) dehydrogenase 20.021
MLXMAX-like protein X0.021
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.020
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 50.019
SOD1superoxide dismutase 1, soluble0.018
SIGMAR1sigma non-opioid intracellular receptor 10.018
HUWE1HECT, UBA and WWE domain containing 10.018
URODuroporphyrinogen decarboxylase0.017
MMS19MMS19 nucleotide excision repair homolog (S. cerevisiae)0.017
DAXXdeath-domain associated protein0.017
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.016
MTA1metastasis associated 10.016
MRPL24mitochondrial ribosomal protein L240.016
EIF3CLeukaryotic translation initiation factor 3, subunit C-like0.016
CECR5cat eye syndrome chromosome region, candidate 50.016
MRPL16mitochondrial ribosomal protein L160.015
BIDBH3 interacting domain death agonist0.015
MAXMYC associated factor X0.014
MRPL23mitochondrial ribosomal protein L230.014
SP1Sp1 transcription factor0.013
FXNfrataxin0.012
GOT2glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)0.012
NDUFA9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa0.011
PES1pescadillo homolog 1, containing BRCT domain (zebrafish)0.011
TH1LTH1-like (Drosophila)0.011
APOOapolipoprotein O0.011
HSPA8heat shock 70kDa protein 80.010
TIMM50translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)0.010
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Phbprohibitin0.333
Clppcaseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)0.311
Mrpl12mitochondrial ribosomal protein L120.284
Phb2prohibitin 20.247
Mrpl28mitochondrial ribosomal protein L280.230
Mrpl52mitochondrial ribosomal protein L520.174
Samm50sorting and assembly machinery component 50 homolog (S. cerevisiae)0.150
Ndufab1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 10.117
Mrps15mitochondrial ribosomal protein S150.095
Nop10NOP10 ribonucleoprotein homolog (yeast)0.077
Dctpp1dCTP pyrophosphatase 10.075
Mrpl11mitochondrial ribosomal protein L110.061
Park7Parkinson disease (autosomal recessive, early onset) 70.058
Pam16presequence translocase-asssociated motor 16 homolog (S. cerevisiae)0.048
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.046
Slc39a4solute carrier family 39 (zinc transporter), member 40.041
Gcshglycine cleavage system protein H (aminomethyl carrier)0.037
N6amt2N-6 adenine-specific DNA methyltransferase 2 (putative)0.036
Steap3STEAP family member 30.034
Mrps12mitochondrial ribosomal protein S120.033
Hbb-b1hemoglobin, beta adult major chain0.031
Pcsk4proprotein convertase subtilisin/kexin type 40.029
Znhit1zinc finger, HIT domain containing 10.028
Cops6COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)0.027
Mrps25mitochondrial ribosomal protein S250.027
Mrps28mitochondrial ribosomal protein S280.026
Mrpl23mitochondrial ribosomal protein L230.025
Mecrmitochondrial trans-2-enoyl-CoA reductase0.024
Atp5oATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.022
Chchd1coiled-coil-helix-coiled-coil-helix domain containing 10.021
Stoml2stomatin (Epb7.2)-like 20.020
MaxMax protein0.020
Naa10N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 100.019
Mrps17mitochondrial ribosomal protein S170.018
Tmem147transmembrane protein 1470.017
Adsladenylosuccinate lyase0.016
Slc31a1solute carrier family 31, member 10.016
Stim2stromal interaction molecule 20.015
Lsmd1LSM domain containing 10.014
Psmb3proteasome (prosome, macropain) subunit, beta type 30.014
Tomm5translocase of outer mitochondrial membrane 5 homolog (yeast)0.014
Tpi1triosephosphate isomerase 10.013
Trp53transformation related protein 530.013
Ndufa8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 80.012
Mrpl13mitochondrial ribosomal protein L130.012
Mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase0.012
Tlr4toll-like receptor 40.011
Fxnfrataxin0.011
Timm13translocase of inner mitochondrial membrane 13 homolog (yeast)0.011
Ptcd2pentatricopeptide repeat domain 20.010
Mrpl44mitochondrial ribosomal protein L440.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
PVRpoliovirus receptor0.017
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism