The network for 'hormone catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hormone catabolic process

The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.

NameDescriptionProbabilityFunc Analog Organism
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.999
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.998
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.986
CCL3chemokine (C-C motif) ligand 30.806
TUBB8tubulin, beta 80.314
MTHFD1methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase0.219
GABRA3gamma-aminobutyric acid (GABA) A receptor, alpha 30.095
UGT2B15UDP glucuronosyltransferase 2 family, polypeptide B150.081
UGT2B17UDP glucuronosyltransferase 2 family, polypeptide B170.075
SEC23IPSEC23 interacting protein0.035
UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B280.030
LARP4La ribonucleoprotein domain family, member 40.029
AP3B1adaptor-related protein complex 3, beta 1 subunit0.025
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.023
SH3BGRLSH3 domain binding glutamic acid-rich protein like0.021
AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)0.020
FOLH1folate hydrolase (prostate-specific membrane antigen) 10.018
MTFR1mitochondrial fission regulator 10.018
CCDC6coiled-coil domain containing 60.018
MRVI1murine retrovirus integration site 1 homolog0.018
DNAJC10DnaJ (Hsp40) homolog, subfamily C, member 100.017
AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.017
UGGT1UDP-glucose glycoprotein glucosyltransferase 10.017
ZW10ZW10, kinetochore associated, homolog (Drosophila)0.016
IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha0.016
GUF1GUF1 GTPase homolog (S. cerevisiae)0.015
CD302CD302 molecule0.015
NR1H4nuclear receptor subfamily 1, group H, member 40.015
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.015
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.015
BDKRB2bradykinin receptor B20.015
RNASE4ribonuclease, RNase A family, 40.014
UGT2B4UDP glucuronosyltransferase 2 family, polypeptide B40.014
UGT2B10UDP glucuronosyltransferase 2 family, polypeptide B100.014
MAN1A1mannosidase, alpha, class 1A, member 10.013
NQO1NAD(P)H dehydrogenase, quinone 10.013
AADACarylacetamide deacetylase (esterase)0.013
MAPK14mitogen-activated protein kinase 140.012
HRGhistidine-rich glycoprotein0.012
FAM83Ffamily with sequence similarity 83, member F0.012
PIRpirin (iron-binding nuclear protein)0.012
RAD50RAD50 homolog (S. cerevisiae)0.012
PRLRprolactin receptor0.012
ALDH1A1aldehyde dehydrogenase 1 family, member A10.012
SLCO1B3solute carrier organic anion transporter family, member 1B30.011
CPSF2cleavage and polyadenylation specific factor 2, 100kDa0.011
LRRC31leucine rich repeat containing 310.011
RAP2BRAP2B, member of RAS oncogene family0.011
ECDecdysoneless homolog (Drosophila)0.011
SIsucrase-isomaltase (alpha-glucosidase)0.011
SLC26A3solute carrier family 26, member 30.011
CES1carboxylesterase 10.011
F13Bcoagulation factor XIII, B polypeptide0.011
NFRKBnuclear factor related to kappaB binding protein0.011
MBTPS2membrane-bound transcription factor peptidase, site 20.011
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.011
TM4SF4transmembrane 4 L six family member 40.011
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.010
TFF3trefoil factor 3 (intestinal)0.010
FRKfyn-related kinase0.010
KBTBD3kelch repeat and BTB (POZ) domain containing 30.010
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.010
BCMO1beta-carotene 15,15'-monooxygenase 10.010
ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide0.010
TSPAN8tetraspanin 80.010
HNF4Ghepatocyte nuclear factor 4, gamma0.010
METTL7Amethyltransferase like 7A0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG13310CG13310 gene product from transcript CG13310-RA0.876
Ugt35aUDP-glycosyltransferase 35a0.424
proPO-A1prophenol oxidase A10.298
CG9360CG9360 gene product from transcript CG9360-RA0.238
CG2736CG2736 gene product from transcript CG2736-RA0.215
Acph-1Acid phosphatase 10.208
NtRCG6698 gene product from transcript CG6698-RA0.204
Cyp6a21CG10247 gene product from transcript CG10247-RA0.202
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.166
CG11149CG11149 gene product from transcript CG11149-RD0.166
Jheh3Juvenile hormone epoxide hydrolase 30.162
CG33307CG33307 gene product from transcript CG33307-RA0.161
CG11147CG11147 gene product from transcript CG11147-RA0.157
MenMalic enzyme0.155
Sr-CIScavenger receptor class C, type I0.154
CG3967CG3967 gene product from transcript CG3967-RC0.153
CG5973CG5973 gene product from transcript CG5973-RA0.150
glob1globin 10.150
CG6426CG6426 gene product from transcript CG6426-RA0.143
CG1124CG1124 gene product from transcript CG1124-RA0.142
CG15096CG15096 gene product from transcript CG15096-RA0.139
CG7272CG7272 gene product from transcript CG7272-RA0.137
CG3702CG3702 gene product from transcript CG3702-RA0.136
CG8773CG8773 gene product from transcript CG8773-RB0.127
Est-6Esterase 60.126
Cyp4d21CG6730 gene product from transcript CG6730-RA0.121
Syx4Syntaxin 40.112
Aldh-IIIAldehyde dehydrogenase type III0.109
CG42807CG42807 gene product from transcript CG42807-RA0.108
CG13631CG13631 gene product from transcript CG13631-RA0.101
CG13360CG13360 gene product from transcript CG13360-RA0.100
CG17928CG17928 gene product from transcript CG17928-RA0.099
Ugt86DcCG4739 gene product from transcript CG4739-RA0.098
CG12746CG12746 gene product from transcript CG12746-RD0.096
CG14457CG14457 gene product from transcript CG14457-RA0.095
Ugt86DhCG4772 gene product from transcript CG4772-RA0.091
CG8193CG8193 gene product from transcript CG8193-RA0.090
Myo61FMyosin 61F0.090
CG6834CG6834 gene product from transcript CG6834-RA0.088
CG4721CG4721 gene product from transcript CG4721-RA0.088
Hexo2Hexosaminidase 20.087
CG4950CG4950 gene product from transcript CG4950-RB0.085
Cyp12e1CG14680 gene product from transcript CG14680-RC0.085
Cyp4e2Cytochrome P450-4e20.085
Fkbp13CG9847 gene product from transcript CG9847-RC0.084
vir-1virus-induced RNA 10.084
CG10562CG10562 gene product from transcript CG10562-RA0.082
Or22aOdorant receptor 22a0.081
sxe2sex-specific enzyme 20.081
Est-PEsterase P0.080
CG14856CG14856 gene product from transcript CG14856-RA0.080
Cyp6d4CG12800 gene product from transcript CG12800-RA0.079
CG10433CG10433 gene product from transcript CG10433-RA0.077
CG5361CG5361 gene product from transcript CG5361-RA0.077
CG15828CG15828 gene product from transcript CG15828-RC0.075
Ugt36BaCG13270 gene product from transcript CG13270-RA0.074
CG13284CG13284 gene product from transcript CG13284-RA0.073
CG3376CG3376 gene product from transcript CG3376-RB0.071
Trf4-1CG11265 gene product from transcript CG11265-RE0.069
CG5390CG5390 gene product from transcript CG5390-RA0.069
Cyp4e1Cytochrome P450-4e10.068
CG1092CG1092 gene product from transcript CG1092-RA0.067
CG6126CG6126 gene product from transcript CG6126-RA0.067
CG13875CG13875 gene product from transcript CG13875-RA0.067
CG9512CG9512 gene product from transcript CG9512-RA0.067
CG3246CG3246 gene product from transcript CG3246-RA0.066
CG10184CG10184 gene product from transcript CG10184-RA0.066
Ugt86DjCG15902 gene product from transcript CG15902-RA0.066
CG4239CG4239 gene product from transcript CG4239-RA0.066
homerCG11324 gene product from transcript CG11324-RC0.063
CG1941CG1941 gene product from transcript CG1941-RA0.063
Cyp4d14CG3540 gene product from transcript CG3540-RA0.062
Cyp12a4CG6042 gene product from transcript CG6042-RA0.062
CG9497CG9497 gene product from transcript CG9497-RA0.060
CG18507CG18507 gene product from transcript CG18507-RB0.060
MP1Melanization Protease 10.060
CG16732CG16732 gene product from transcript CG16732-RB0.059
CG4822CG4822 gene product from transcript CG4822-RB0.059
CG6910CG6910 gene product from transcript CG6910-RB0.058
CG10553CG10553 gene product from transcript CG10553-RA0.058
CG18327CG18327 gene product from transcript CG18327-RA0.057
CG13002CG13002 gene product from transcript CG13002-RA0.057
CG17026CG17026 gene product from transcript CG17026-RA0.057
CG13658CG13658 gene product from transcript CG13658-RB0.057
CG18249CG18249 gene product from transcript CG18249-RB0.057
CG10051CG10051 gene product from transcript CG10051-RA0.053
Rh50CG7499 gene product from transcript CG7499-RA0.053
PH4alphaEFBprolyl-4-hydroxylase-alpha EFB0.052
CG33012CG33012 gene product from transcript CG33012-RA0.052
CG18324CG18324 gene product from transcript CG18324-RB0.052
CG9642CG9642 gene product from transcript CG9642-RA0.051
CG9743CG9743 gene product from transcript CG9743-RA0.051
CG31103CG31103 gene product from transcript CG31103-RB0.051
Pbprp3Pheromone-binding protein-related protein 30.051
CG33120CG33120 gene product from transcript CG33120-RA0.051
CG12703CG12703 gene product from transcript CG12703-RA0.051
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ren1renin 1 structural0.234
Leprleptin receptor0.076
Agtr1aangiotensin II receptor, type 1a0.050
Glis2GLIS family zinc finger 20.036
Thrathyroid hormone receptor alpha0.030
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.028
Slc12a1solute carrier family 12, member 10.018
Aqp2aquaporin 20.017
Vav3vav 3 oncogene0.015
Vav2vav 2 oncogene0.011
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.680
Gsta5glutathione S-transferase Yc2 subunit0.669
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.560
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.427
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.401
Mgst2microsomal glutathione S-transferase 20.334
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.249
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.219
Akap14A kinase (PRKA) anchor protein 140.190
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.150
Anpepalanyl (membrane) aminopeptidase0.149
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.131
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.131
LOC494499LOC494499 protein0.114
Ugt1a5UDP glucuronosyltransferase 1 family, polypeptide A50.110
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.092
RGD1309414similar to KIAA0913 protein0.087
Nat2N-acetyltransferase 20.077
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.077
Akr1c14aldo-keto reductase family 1, member C140.074
Ugt1a3UDP glycosyltransferase 1 family, polypeptide A30.068
Sult2a2sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 20.060
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.058
PorP450 (cytochrome) oxidoreductase0.056
Ltbrlymphotoxin beta receptor (TNFR superfamily, member 3)0.051
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.047
RGD1305347similar to RIKEN cDNA 2610528J110.044
Olr1530olfactory receptor 15300.043
SnrkSNF related kinase0.037
Phexphosphate regulating endopeptidase homolog, X-linked0.036
FcgrtFc fragment of IgG, receptor, transporter, alpha0.036
Otcornithine carbamoyltransferase0.035
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.035
Nmuneuromedin U0.034
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.034
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.034
Apobapolipoprotein B0.033
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.032
Cyp3a9cytochrome P450, family 3, subfamily a, polypeptide 90.029
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.028
Olr1366olfactory receptor 13660.027
Rag1recombination activating gene 10.026
Olr1191olfactory receptor 11910.026
Metmet proto-oncogene0.026
Ddcdopa decarboxylase (aromatic L-amino acid decarboxylase)0.023
Irf2interferon regulatory factor 20.021
Chpcalcium binding protein p220.021
Gnsglucosamine (N-acetyl)-6-sulfatase0.021
Akr1d1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)0.020
Haao3-hydroxyanthranilate 3,4-dioxygenase0.020
Fabp2fatty acid binding protein 2, intestinal0.020
Ephx1epoxide hydrolase 1, microsomal0.020
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.019
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.019
Slco1a1solute carrier organic anion transporter family, member 1a10.019
Flt1FMS-related tyrosine kinase 10.019
Keg1kidney expressed gene 10.019
Vcsa2variable coding sequence A20.018
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.017
Pctpphosphatidylcholine transfer protein0.017
Ddx4DEAD (Asp-Glu-Ala-Asp) box polypeptide 40.017
Clca4chloride channel accessory 40.016
LOC690507similar to Vomeromodulin0.016
Ces1ecarboxylesterase 1E0.016
Slc22a18solute carrier family 22, member 180.016
Pigrpolymeric immunoglobulin receptor0.016
Olr1082olfactory receptor 10820.016
Olr1347olfactory receptor 13470.016
Ugt1a2UDP glucuronosyltransferase 1 family, polypeptide A20.015
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.015
Ugt1a8UDP glycosyltransferase 1 family, polypeptide A80.015
Col4a3collagen, type IV, alpha 30.015
Olr1280olfactory receptor 12800.014
Cps1carbamoyl-phosphate synthetase 10.014
Fgf1fibroblast growth factor 10.014
Olr1226olfactory receptor 12260.014
Tbl1xr1transducin (beta)-like 1 X-linked receptor 10.013
LOC293989cytochrome P450-like0.013
Egfrepidermal growth factor receptor0.013
Fn1fibronectin 10.013
Ugt1a1UDP glucuronosyltransferase 1 family, polypeptide A10.013
L3mbtl3l(3)mbt-like 3 (Drosophila)0.013
Crygfcrystallin, gamma F0.013
Acsm2acyl-CoA synthetase medium-chain family member 20.012
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.012
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.012
Tns1tensin 10.012
Olr1697olfactory receptor 16970.012
Vom2r50vomeronasal 2 receptor, 500.012
Pttg1ippituitary tumor-transforming 1 interacting protein0.012
Enpp1ectonucleotide pyrophosphatase/phosphodiesterase 10.012
Plxnb2plexin B20.012
Adssadenylosuccinate synthase0.012
Il4rainterleukin 4 receptor, alpha0.011
Nqo1NAD(P)H dehydrogenase, quinone 10.011
Galnt1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)0.011
Il2rainterleukin 2 receptor, alpha0.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism