The network for 'regulation of transcription factor import into nucleus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transcription factor import into nucleus

Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.

NameDescriptionProbabilityFunc Analog Organism
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.994
SMAD3SMAD family member 30.994
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.989
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.974
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.959
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.951
SMAD2SMAD family member 20.951
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.917
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.889
IL1Binterleukin 1, beta0.874
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.824
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.814
CCL4chemokine (C-C motif) ligand 40.792
SMAD1SMAD family member 10.778
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.766
TNFAIP3tumor necrosis factor, alpha-induced protein 30.724
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.691
FLNAfilamin A, alpha0.617
SH2D4ASH2 domain containing 4A0.617
SMURF2SMAD specific E3 ubiquitin protein ligase 20.612
BTRCbeta-transducin repeat containing0.552
SMAD5SMAD family member 50.523
MYD88myeloid differentiation primary response gene (88)0.522
FASFas (TNF receptor superfamily, member 6)0.520
CCR5chemokine (C-C motif) receptor 50.516
TNIP2TNFAIP3 interacting protein 20.493
CXCL3chemokine (C-X-C motif) ligand 30.491
IL8interleukin 80.459
SMAD7SMAD family member 70.443
BCL3B-cell CLL/lymphoma 30.432
FLNBfilamin B, beta0.431
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.398
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.393
FADDFas (TNFRSF6)-associated via death domain0.388
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.323
LATlinker for activation of T cells0.291
BIRC3baculoviral IAP repeat containing 30.290
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.275
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.273
CKAP5cytoskeleton associated protein 50.272
MAP3K8mitogen-activated protein kinase kinase kinase 80.255
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.231
CFLARCASP8 and FADD-like apoptosis regulator0.228
PSEN2presenilin 2 (Alzheimer disease 4)0.224
IGF1Rinsulin-like growth factor 1 receptor0.216
TNIP1TNFAIP3 interacting protein 10.212
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.211
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.208
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.202
ICAM1intercellular adhesion molecule 10.187
CYLDcylindromatosis (turban tumor syndrome)0.186
YAP1Yes-associated protein 10.178
DSG2desmoglein 20.177
MAP2K5mitogen-activated protein kinase kinase 50.168
PSEN1presenilin 10.166
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.153
CCL8chemokine (C-C motif) ligand 80.152
C3orf15chromosome 3 open reading frame 150.150
RNF31ring finger protein 310.146
TRAF1TNF receptor-associated factor 10.145
RANBP3RAN binding protein 30.140
ACTN4actinin, alpha 40.138
DCAF7DDB1 and CUL4 associated factor 70.134
SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein)0.134
BBS10Bardet-Biedl syndrome 100.134
TNFtumor necrosis factor0.131
RECQLRecQ protein-like (DNA helicase Q1-like)0.131
ZNF84zinc finger protein 840.130
ZNF260zinc finger protein 2600.130
RACGAP1Rac GTPase activating protein 10.129
CCL20chemokine (C-C motif) ligand 200.127
IL1R2interleukin 1 receptor, type II0.122
CASP8caspase 8, apoptosis-related cysteine peptidase0.121
PKD2polycystic kidney disease 2 (autosomal dominant)0.119
CCL2chemokine (C-C motif) ligand 20.117
STAT6signal transducer and activator of transcription 6, interleukin-4 induced0.113
IL1R1interleukin 1 receptor, type I0.112
CCR1chemokine (C-C motif) receptor 10.109
AXIN1axin 10.108
CXCL2chemokine (C-X-C motif) ligand 20.107
TNFRSF9tumor necrosis factor receptor superfamily, member 90.106
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.104
IL6interleukin 6 (interferon, beta 2)0.104
CXCL9chemokine (C-X-C motif) ligand 90.100
MAP3K3mitogen-activated protein kinase kinase kinase 30.098
SMAD4SMAD family member 40.098
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.094
CHUKconserved helix-loop-helix ubiquitous kinase0.094
TRIM25tripartite motif containing 250.092
IDEinsulin-degrading enzyme0.091
FBXW11F-box and WD repeat domain containing 110.090
CTNND1catenin (cadherin-associated protein), delta 10.087
RNF11ring finger protein 110.086
IRS2insulin receptor substrate 20.085
ACTN1actinin, alpha 10.084
GLI1GLI family zinc finger 10.083
PACSIN2protein kinase C and casein kinase substrate in neurons 20.081
RCN3reticulocalbin 3, EF-hand calcium binding domain0.077
ZNF585Azinc finger protein 585A0.074
TXNthioredoxin0.073
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
npp-7Protein NPP-70.012
pyr-1Protein PYR-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
perperiod0.158
Cul-2Cullin-20.098
HcfHost cell factor0.050
Pi3K92ECG4141 gene product from transcript CG4141-RB0.047
slmbsupernumerary limbs0.040
Toll-7CG8595 gene product from transcript CG8595-RA0.038
TlToll0.033
Cul-3Cullin-30.033
Act87EActin 87E0.033
GLazGlial Lazarillo0.032
ttvtout-velu0.032
Mlc1Myosin alkali light chain 10.030
CanBCalcineurin B0.028
tkvthickveins0.026
Toll-6CG7250 gene product from transcript CG7250-RA0.026
scrascraps0.025
crolcrooked legs0.024
pumpumilio0.024
Nek2CG17256 gene product from transcript CG17256-RA0.024
klgklingon0.023
Eb1CG3265 gene product from transcript CG3265-RF0.021
TolloCG6890 gene product from transcript CG6890-RA0.021
Vap-33-1CG5014 gene product from transcript CG5014-RB0.020
Eip63F-1Ecdysone-induced protein 63F 10.020
DatDopamine N acetyltransferase0.018
staistathmin0.018
l(2)gllethal (2) giant larvae0.018
Cpr62BcCuticular protein 62Bc0.017
traltrailer hitch0.017
cpacapping protein alpha0.017
CG31904CG31904 gene product from transcript CG31904-RD0.016
sdscalloped0.016
SxlSex lethal0.016
ovoCG6824 gene product from transcript CG6824-RE0.016
lkb1CG9374 gene product from transcript CG9374-RJ0.016
cicubitus interruptus0.016
Ca-P60ACalcium ATPase at 60A0.015
RnrLRibonucleoside diphosphate reductase large subunit0.015
Lis-1Lissencephaly-10.014
ecechinus0.014
hyxhyrax0.014
ensensconsin0.014
CG16718CG16718 gene product from transcript CG16718-RA0.014
Zyx102EFCG32018 gene product from transcript CG32018-RA0.014
JhI-1Juvenile hormone-inducible protein 10.014
ctpcut up0.014
CG32810CG32810 gene product from transcript CG32810-RB0.013
pr-set7CG3307 gene product from transcript CG3307-RC0.013
Spc105RSpc105-related0.013
panpangolin0.013
Eip93FCG18389 gene product from transcript CG18389-RB0.013
rho-5rhomboid-50.013
Tm2Tropomyosin 20.012
nudECG8104 gene product from transcript CG8104-RB0.012
Tbp-1Tat-binding protein-10.012
Src64BSrc oncogene at 64B0.012
CanB2Calcineurin B20.012
aretarrest0.012
Akt1CG4006 gene product from transcript CG4006-RA0.012
ArgkArginine kinase0.012
CG10414CG10414 gene product from transcript CG10414-RA0.011
forforaging0.011
ATPsyn-betaATP synthase-beta0.011
smosmoothened0.011
par-6CG5884 gene product from transcript CG5884-RA0.011
porporcupine0.011
shgshotgun0.011
dadaughterless0.011
CG5355CG5355 gene product from transcript CG5355-RA0.011
RanBPMRan-binding protein M0.011
CG4962CG4962 gene product from transcript CG4962-RA0.011
dnr1defense repressor 10.011
Pka-C1cAMP-dependent protein kinase 10.011
CG13322CG13322 gene product from transcript CG13322-RA0.011
ykiyorkie0.010
CG16885CG16885 gene product from transcript CG16885-RA0.010
RYBPRing and YY1 Binding Protein0.010
wgwingless0.010
picoCG11940 gene product from transcript CG11940-RA0.010
cutletCG33122 gene product from transcript CG33122-RA0.010
simjsimjang0.010
IppInositol polyphosphate 1-phosphatase0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tnftumor necrosis factor0.993
Trp53transformation related protein 530.989
Ctnnb1catenin (cadherin associated protein), beta 10.949
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.926
Apcadenomatosis polyposis coli0.922
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.901
Ptenphosphatase and tensin homolog0.795
Casp4caspase 4, apoptosis-related cysteine peptidase0.724
Fgfr2fibroblast growth factor receptor 20.677
Rararetinoic acid receptor, alpha0.648
Fgfr1fibroblast growth factor receptor 10.616
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.600
Lyz2lysozyme 20.587
Trp63transformation related protein 630.575
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.573
Rxraretinoid X receptor alpha0.439
Cyldcylindromatosis (turban tumor syndrome)0.410
Arandrogen receptor0.406
Cd28CD28 antigen0.369
Map3k14mitogen-activated protein kinase kinase kinase 140.367
Leprleptin receptor0.347
Casp1caspase 10.341
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)0.324
Il6stinterleukin 6 signal transducer0.254
Ikbkbinhibitor of kappaB kinase beta0.253
Stat3signal transducer and activator of transcription 30.218
Rnf31ring finger protein 310.216
EdaraddEDAR (ectodysplasin-A receptor)-associated death domain0.215
Ppp3cbprotein phosphatase 3, catalytic subunit, beta isoform0.195
Itgb1integrin beta 1 (fibronectin receptor beta)0.191
Pax8paired box gene 80.184
Gli3GLI-Kruppel family member GLI30.174
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.161
Cul3cullin 30.159
Rargretinoic acid receptor, gamma0.156
Il1r1interleukin 1 receptor, type I0.154
Edaectodysplasin-A0.152
Ncoa3nuclear receptor coactivator 30.134
Bcl2B-cell leukemia/lymphoma 20.131
Htthuntingtin0.130
Axin1axin 10.129
Sox9SRY-box containing gene 90.129
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.126
Smad3MAD homolog 3 (Drosophila)0.109
Stim2stromal interaction molecule 20.105
Il10interleukin 100.100
Vdrvitamin D receptor0.098
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.098
FasFas (TNF receptor superfamily member 6)0.097
Cux1cut-like homeobox 10.094
Csf1colony stimulating factor 1 (macrophage)0.093
Cd44CD44 antigen0.091
Il1binterleukin 1 beta0.088
Ghrgrowth hormone receptor0.087
Il7interleukin 70.083
Cav1caveolin 1, caveolae protein0.083
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.081
Cand1cullin associated and neddylation disassociated 10.080
Stat6signal transducer and activator of transcription 60.079
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.079
Gli2GLI-Kruppel family member GLI20.078
Thbs1thrombospondin 10.077
Rptorregulatory associated protein of MTOR, complex 10.075
Kpna1karyopherin (importin) alpha 10.074
Rnf115ring finger protein 1150.069
Smosmoothened homolog (Drosophila)0.068
Nos2nitric oxide synthase 2, inducible0.067
Cops2COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)0.066
Bcl3B-cell leukemia/lymphoma 30.065
Mapkap1mitogen-activated protein kinase associated protein 10.062
Psen1presenilin 10.062
Rb1retinoblastoma 10.061
Cxcr5chemokine (C-X-C motif) receptor 50.060
Arl8bADP-ribosylation factor-like 8B0.059
Nr3c1nuclear receptor subfamily 3, group C, member 10.059
Lrp6low density lipoprotein receptor-related protein 60.058
Grb10growth factor receptor bound protein 100.058
Bmp4bone morphogenetic protein 40.058
Smad2MAD homolog 2 (Drosophila)0.058
Vhlvon Hippel-Lindau tumor suppressor0.056
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.055
Emx2empty spiracles homolog 2 (Drosophila)0.053
Traf6TNF receptor-associated factor 60.052
SharpinSHANK-associated RH domain interacting protein0.052
Edarectodysplasin-A receptor0.051
Il1r2interleukin 1 receptor, type II0.050
Toxthymocyte selection-associated high mobility group box0.050
Nkx3-1NK-3 transcription factor, locus 1 (Drosophila)0.049
Yap1yes-associated protein 10.049
Eya1eyes absent 1 homolog (Drosophila)0.047
Ptpn11protein tyrosine phosphatase, non-receptor type 110.047
Ltalymphotoxin A0.047
Cbx5chromobox homolog 5 (Drosophila HP1a)0.046
Bcl6B-cell leukemia/lymphoma 60.046
Hprthypoxanthine guanine phosphoribosyl transferase0.046
Fam96afamily with sequence similarity 96, member A0.046
Myd88myeloid differentiation primary response gene 880.044
Stim1stromal interaction molecule 10.044
Tgfb1transforming growth factor, beta 10.043
Eya2eyes absent 2 homolog (Drosophila)0.043
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.014
Tnks2tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 20.012
RragaRas-related GTP binding A0.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
KSS1Kss1p0.094
CNB1Cnb1p0.085
ARP4Arp4p0.050
TCO89Tco89p0.048
TRA1Tra1p0.042
FUS3Fus3p0.042
NUP49Nup49p0.040
KDX1Kdx1p0.033
CNA1Cna1p0.032
NUP82Nup82p0.031
MSG5Msg5p0.031
NSP1Nsp1p0.030
RCN1Rcn1p0.028
KOG1Kog1p0.028
SLT2Slt2p0.026
AHP1Ahp1p0.026
ATG13Atg13p0.024
EPL1Epl1p0.023
RGD2Rgd2p0.021
EAF1Eaf1p0.021
SWC7Swc7p0.020
STT4Stt4p0.020
CRM1Crm1p0.020
CDC55Cdc55p0.019
SRD1Srd1p0.018
SRP1Srp1p0.017
YLR264C-Ahypothetical protein0.017
LEU2Leu2p0.017
RLM1Rlm1p0.017
TRX2Trx2p0.017
YLR162Whypothetical protein0.017
YPK1Ypk1p0.017
YOL038C-Ahypothetical protein0.016
ATG29Atg29p0.016
RHO1Rho1p0.016
ARP10Arp10p0.016
ALD6Ald6p0.016
MER1Mer1p0.015
SLM2Slm2p0.015
CAR1Car1p0.015
EAF3Eaf3p0.015
CUP1-1Cup1-1p0.015
YLR042Chypothetical protein0.015
SPL2Spl2p0.015
GFA1Gfa1p0.015
YPL088Whypothetical protein0.015
YIL151Chypothetical protein0.015
YLR108Chypothetical protein0.014
LUC7Luc7p0.014
ARF2Arf2p0.014
STE2Ste2p0.014
SWC3Swc3p0.014
SOD1Sod1p0.014
YPR157Whypothetical protein0.014
YBR013Chypothetical protein0.014
YAR068Whypothetical protein0.014
ECM14Ecm14p0.014
BSC1Bsc1p0.014
YIR035Chypothetical protein0.013
ARG8Arg8p0.013
UPS3Ups3p0.013
UBP11Ubp11p0.013
AUA1Aua1p0.013
CHA1Cha1p0.013
REE1Ree1p0.013
ATP6Atp6p0.013
OPT2Opt2p0.013
YNL058Chypothetical protein0.013
ZPS1Zps1p0.013
HXT3Hxt3p0.013
HPF1Hpf1p0.013
CPD1Cpd1p0.013
STE7Ste7p0.013
TYE7Tye7p0.013
URA3Ura3p0.013
PTR2Ptr2p0.013
YPL014Whypothetical protein0.013
GYL1Gyl1p0.013
CMP2Cmp2p0.013
UTR4Utr4p0.012
GPR1Gpr1p0.012
FMT1Fmt1p0.012
GCN2Gcn2p0.012
PAR32Par32p0.012
PCT1Pct1p0.012
MEP1Mep1p0.012
CMD1Cmd1p0.012
AIF1Aif1p0.012
CHS1Chs1p0.012
YOL013W-Ahypothetical protein0.012
YML003Whypothetical protein0.012
YLR040Chypothetical protein0.012
CNE1Cne1p0.012
YCH1Ych1p0.012
ATG2Atg2p0.012
FRT1Frt1p0.012
ACP1Acp1p0.012
FMN1Fmn1p0.012
PBS2Pbs2p0.012
SCM4Scm4p0.012