The network for 'prostate gland development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

prostate gland development

The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.

NameDescriptionProbabilityFunc Analog Organism
CREBBPCREB binding protein0.872
RARAretinoic acid receptor, alpha0.780
ESR1estrogen receptor 10.747
PTPN11protein tyrosine phosphatase, non-receptor type 110.682
RXRAretinoid X receptor, alpha0.667
MED25mediator complex subunit 250.660
POU3F2POU class 3 homeobox 20.522
JAG1jagged 10.471
PAX3paired box 30.454
FGF1fibroblast growth factor 1 (acidic)0.416
SMAD7SMAD family member 70.349
NCOA1nuclear receptor coactivator 10.296
FGF10fibroblast growth factor 100.261
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.245
NCOA2nuclear receptor coactivator 20.208
BMP7bone morphogenetic protein 70.207
EGFRepidermal growth factor receptor0.202
PPP5Cprotein phosphatase 5, catalytic subunit0.169
MDM2Mdm2 p53 binding protein homolog (mouse)0.166
MAML1mastermind-like 1 (Drosophila)0.160
FGFR1fibroblast growth factor receptor 10.159
TIMP2TIMP metallopeptidase inhibitor 20.158
STRADASTE20-related kinase adaptor alpha0.148
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.144
SPDEFSAM pointed domain containing ets transcription factor0.139
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.137
PPM1Fprotein phosphatase, Mg2+/Mn2+ dependent, 1F0.136
MYOD1myogenic differentiation 10.136
FOXD3forkhead box D30.134
POU5F1POU class 5 homeobox 10.130
TPP1tripeptidyl peptidase I0.111
THBS2thrombospondin 20.111
WDR83WD repeat domain 830.110
CCND1cyclin D10.110
KRT5keratin 50.107
MEOX2mesenchyme homeobox 20.105
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.101
CAV1caveolin 1, caveolae protein, 22kDa0.090
UHRF2ubiquitin-like with PHD and ring finger domains 20.088
NRIP1nuclear receptor interacting protein 10.087
IRS1insulin receptor substrate 10.086
CABLES1Cdk5 and Abl enzyme substrate 10.083
FZD1frizzled homolog 1 (Drosophila)0.082
SIAH1seven in absentia homolog 1 (Drosophila)0.081
FGF2fibroblast growth factor 2 (basic)0.081
FHL2four and a half LIM domains 20.077
MYLK2myosin light chain kinase 20.076
PHF17PHD finger protein 170.072
S100A6S100 calcium binding protein A60.072
ZBED1zinc finger, BED-type containing 10.070
YAP1Yes-associated protein 10.066
SATB2SATB homeobox 20.065
PRSS21protease, serine, 21 (testisin)0.065
RB1retinoblastoma 10.064
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.060
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.060
PURApurine-rich element binding protein A0.060
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.059
PTPN1protein tyrosine phosphatase, non-receptor type 10.059
TIMP1TIMP metallopeptidase inhibitor 10.059
SCRIBscribbled homolog (Drosophila)0.058
STRADBSTE20-related kinase adaptor beta0.057
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.055
LAMP1lysosomal-associated membrane protein 10.054
NCOA7nuclear receptor coactivator 70.054
FTH1ferritin, heavy polypeptide 10.053
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.053
ARandrogen receptor0.052
SALL2sal-like 2 (Drosophila)0.051
MARCKSL1MARCKS-like 10.050
ARNTaryl hydrocarbon receptor nuclear translocator0.050
IGF1Rinsulin-like growth factor 1 receptor0.050
NCOR2nuclear receptor corepressor 20.050
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.050
FOXA1forkhead box A10.048
KIF5Bkinesin family member 5B0.048
CRIP2cysteine-rich protein 20.048
BMPR1Abone morphogenetic protein receptor, type IA0.047
ARNTLaryl hydrocarbon receptor nuclear translocator-like0.047
NCOA6nuclear receptor coactivator 60.046
CTSDcathepsin D0.046
FGF7fibroblast growth factor 70.045
CDH3cadherin 3, type 1, P-cadherin (placental)0.045
ZFYVE9zinc finger, FYVE domain containing 90.045
JAG2jagged 20.045
RXRBretinoid X receptor, beta0.043
COL1A1collagen, type I, alpha 10.043
NEDD4neural precursor cell expressed, developmentally down-regulated 40.043
CHORDC1cysteine and histidine-rich domain (CHORD) containing 10.042
TCF4transcription factor 40.042
HOXA10homeobox A100.041
EPORerythropoietin receptor0.041
CCND3cyclin D30.041
KAT2BK(lysine) acetyltransferase 2B0.040
S100A2S100 calcium binding protein A20.040
KRT6Ckeratin 6C0.038
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ptenphosphatase and tensin homolog0.999
Fgfr2fibroblast growth factor receptor 20.999
Arandrogen receptor0.998
Pax2paired box gene 20.993
Pax8paired box gene 80.991
Gli3GLI-Kruppel family member GLI30.983
Rargretinoic acid receptor, gamma0.978
Bmp4bone morphogenetic protein 40.977
Fgfr1fibroblast growth factor receptor 10.967
Fgfr3fibroblast growth factor receptor 30.959
Ror2receptor tyrosine kinase-like orphan receptor 20.956
Gli2GLI-Kruppel family member GLI20.953
Shhsonic hedgehog0.949
Pthlhparathyroid hormone-like peptide0.934
Dlx5distal-less homeobox 50.889
Trp53transformation related protein 530.881
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.879
Fgf8fibroblast growth factor 80.851
Sox9SRY-box containing gene 90.847
Rxraretinoid X receptor alpha0.834
Wnt3awingless-related MMTV integration site 3A0.806
Pax3paired box gene 30.802
Hoxa13homeobox A130.800
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.778
Bmp7bone morphogenetic protein 70.756
Ghrgrowth hormone receptor0.736
Pax6paired box gene 60.735
Dok1docking protein 10.735
Ctnnb1catenin (cadherin associated protein), beta 10.721
Sfrp2secreted frizzled-related protein 20.699
Lmx1aLIM homeobox transcription factor 1 alpha0.680
Trp63transformation related protein 630.680
Hes1hairy and enhancer of split 1 (Drosophila)0.679
Cdkn1bcyclin-dependent kinase inhibitor 1B0.679
Foxc1forkhead box C10.649
Gata4GATA binding protein 40.648
Dkk1dickkopf homolog 1 (Xenopus laevis)0.604
Esr2estrogen receptor 2 (beta)0.592
Esr1estrogen receptor 1 (alpha)0.582
Fgf10fibroblast growth factor 100.568
Leprleptin receptor0.566
Sox7SRY-box containing gene 70.556
Fgf18fibroblast growth factor 180.552
Vangl2vang-like 2 (van gogh, Drosophila)0.551
Grb10growth factor receptor bound protein 100.551
Grb2growth factor receptor bound protein 20.550
Nr2f2nuclear receptor subfamily 2, group F, member 20.514
Pitx2paired-like homeodomain transcription factor 20.499
Sox2SRY-box containing gene 20.494
Apcadenomatosis polyposis coli0.493
Hand2heart and neural crest derivatives expressed transcript 20.487
Tcf21transcription factor 210.462
Prlrprolactin receptor0.456
Hoxd13homeobox D130.452
Nkx2-1NK2 homeobox 10.448
Stat5bsignal transducer and activator of transcription 5B0.438
Barx1BarH-like homeobox 10.427
Hoxd11homeobox D110.402
Pou3f3POU domain, class 3, transcription factor 30.395
Emx2empty spiracles homolog 2 (Drosophila)0.389
Meox2mesenchyme homeobox 20.386
Thrbthyroid hormone receptor beta0.380
Pbx1pre B-cell leukemia transcription factor 10.379
Nr2f1nuclear receptor subfamily 2, group F, member 10.342
Fgf3fibroblast growth factor 30.338
Cdx1caudal type homeobox 10.329
Pdx1pancreatic and duodenal homeobox 10.328
Sfrp1secreted frizzled-related protein 10.321
Nr5a1nuclear receptor subfamily 5, group A, member 10.320
Neurog3neurogenin 30.319
Col1a1collagen, type I, alpha 10.311
Insrinsulin receptor0.310
Fgf4fibroblast growth factor 40.303
Efnb2ephrin B20.299
Pgrprogesterone receptor0.298
Gas1growth arrest specific 10.294
Gja3gap junction protein, alpha 30.289
Tbx2T-box 20.289
Notch2Notch gene homolog 2 (Drosophila)0.280
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.278
Kiss1KiSS-1 metastasis-suppressor0.269
Hoxa11homeobox A110.269
Lhx3LIM homeobox protein 30.268
Foxa2forkhead box A20.255
Otx1orthodenticle homolog 1 (Drosophila)0.254
Npr3natriuretic peptide receptor 30.253
Stat5asignal transducer and activator of transcription 5A0.251
Alx4aristaless-like homeobox 40.251
En1engrailed 10.246
Tbx1T-box 10.245
Tgfb2transforming growth factor, beta 20.240
Egfrepidermal growth factor receptor0.237
Adra2badrenergic receptor, alpha 2b0.236
Kitkit oncogene0.234
Otx2orthodenticle homolog 2 (Drosophila)0.226
Irf9interferon regulatory factor 90.220
Wnt2bwingless related MMTV integration site 2b0.218
Inpp5dinositol polyphosphate-5-phosphatase D0.215
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
S100a10S100 calcium binding protein A100.446
S100a11S100 calcium binding protein A11 (calizzarin)0.172
Anxa2annexin A20.153
S100a6S100 calcium binding protein A60.063
Lgals3lectin, galactoside-binding, soluble, 30.051
Anxa5annexin A50.031
Timp1TIMP metallopeptidase inhibitor 10.028
DbpD site of albumin promoter (albumin D-box) binding protein0.025
Cd151CD151 molecule (Raph blood group)0.025
Anxa1annexin A10.024
Ccl2chemokine (C-C motif) ligand 20.021
Nr1d2nuclear receptor subfamily 1, group D, member 20.019
Stip1stress-induced phosphoprotein 10.017
Krt5keratin 50.016
Zfp469zinc finger protein 4690.015
Foxe3forkhead box E30.015
Mmp13matrix metallopeptidase 130.014
Serpinb1aserine (or cysteine) proteinase inhibitor, clade B, member 1a0.014
Lmnalamin A0.013
Myadmmyeloid-associated differentiation marker0.013
Gdf10growth differentiation factor 100.012
Prkcdbpprotein kinase C, delta binding protein0.012
Itgb1integrin, beta 10.011
Ctrcchymotrypsin C (caldecrin)0.011
Ctsbcathepsin B0.011
Nraddneurotrophin receptor associated death domain0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism