The network for 'proteasomal ubiquitin independent protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

proteasomal ubiquitin independent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.

Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.999
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.998
PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)0.998
POMPproteasome maturation protein0.997
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.997
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.996
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.994
PSMB4proteasome (prosome, macropain) subunit, beta type, 40.994
PSME2proteasome (prosome, macropain) activator subunit 2 (PA28 beta)0.994
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.992
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.992
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.991
CUL3cullin 30.988
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.985
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.984
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.984
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.982
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.980
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.949
PSME1proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)0.938
NFE2L2nuclear factor (erythroid-derived 2)-like 20.934
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.925
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.890
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.880
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.875
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.873
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.837
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.802
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.714
PSMB10proteasome (prosome, macropain) subunit, beta type, 100.668
KEAP1kelch-like ECH-associated protein 10.649
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.598
WNK4WNK lysine deficient protein kinase 40.588
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.534
DAPK1death-associated protein kinase 10.513
PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)0.443
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.395
PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.341
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.279
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.257
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.126
NFE2L1nuclear factor (erythroid-derived 2)-like 10.126
BTBD10BTB (POZ) domain containing 100.084
PRDX1peroxiredoxin 10.082
KBTBD7kelch repeat and BTB (POZ) domain containing 70.082
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.077
SPOPspeckle-type POZ protein0.073
CSNK1A1casein kinase 1, alpha 10.069
COILcoilin0.059
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.059
RAD23ARAD23 homolog A (S. cerevisiae)0.058
SLX1BSLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)0.054
MED28mediator complex subunit 280.046
DCUN1D1DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)0.043
LNX1ligand of numb-protein X 10.041
TAP2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.038
TBCBtubulin folding cofactor B0.037
SHFM1split hand/foot malformation (ectrodactyly) type 10.032
TRIP12thyroid hormone receptor interactor 120.028
MAFKv-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)0.027
TAPBPLTAP binding protein-like0.026
NMIN-myc (and STAT) interactor0.026
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.026
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.025
BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 10.025
PRR13proline rich 130.024
DPP3dipeptidyl-peptidase 30.022
ZFAND5zinc finger, AN1-type domain 50.021
TSC22D4TSC22 domain family, member 40.021
PRMT6protein arginine methyltransferase 60.021
PPP1R14Aprotein phosphatase 1, regulatory (inhibitor) subunit 14A0.020
PFN2profilin 20.018
UCHL5ubiquitin carboxyl-terminal hydrolase L50.018
KLHDC5kelch domain containing 50.018
BAG3BCL2-associated athanogene 30.018
KLHL20kelch-like 20 (Drosophila)0.018
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.016
EIF2AK3eukaryotic translation initiation factor 2-alpha kinase 30.016
SNX20sorting nexin 200.016
DCUN1D5DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)0.015
TIAL1TIA1 cytotoxic granule-associated RNA binding protein-like 10.015
UBE2L6ubiquitin-conjugating enzyme E2L 60.015
FOXP1forkhead box P10.014
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.014
AHRaryl hydrocarbon receptor0.013
CUL1cullin 10.013
GSTO1glutathione S-transferase omega 10.013
SGMS1sphingomyelin synthase 10.012
BANPBTG3 associated nuclear protein0.012
DDIT3DNA-damage-inducible transcript 30.012
KLHL2kelch-like 2, Mayven (Drosophila)0.012
KPNA1karyopherin alpha 1 (importin alpha 5)0.012
CPSF6cleavage and polyadenylation specific factor 6, 68kDa0.012
HOOK3hook homolog 3 (Drosophila)0.012
TXNL1thioredoxin-like 10.012
ARMC8armadillo repeat containing 80.012
OSTF1osteoclast stimulating factor 10.012
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.011
TMSB10thymosin beta 100.011
FAM98Afamily with sequence similarity 98, member A0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Psma2proteasome (prosome, macropain) subunit, alpha type 21.000
Psma5proteasome (prosome, macropain) subunit, alpha type 50.998
Psmb7proteasome (prosome, macropain) subunit, beta type 70.998
Psma7proteasome (prosome, macropain) subunit, alpha type 70.992
Psma1proteasome (prosome, macropain) subunit, alpha type 10.988
Psma3proteasome (prosome, macropain) subunit, alpha type 30.978
Iqcb1IQ calmodulin-binding motif containing 10.978
Psma6proteasome (prosome, macropain) subunit, alpha type 60.952
Psmb6proteasome (prosome, macropain) subunit, beta type 60.928
Psma4proteasome (prosome, macropain) subunit, alpha type 40.910
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.909
Pompproteasome maturation protein0.845
Psmb4proteasome (prosome, macropain) subunit, beta type 40.598
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.557
Psmb3proteasome (prosome, macropain) subunit, beta type 30.453
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.408
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.380
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.284
Psmb2proteasome (prosome, macropain) subunit, beta type 20.277
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.237
Cops5COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)0.211
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.167
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.100
Timm17atranslocase of inner mitochondrial membrane 17a0.086
Parlpresenilin associated, rhomboid-like0.083
Gm10094predicted gene 100940.077
Psmb5proteasome (prosome, macropain) subunit, beta type 50.072
Prdx1peroxiredoxin 10.067
Sec13SEC13 homolog (S. cerevisiae)0.066
Hspe1heat shock protein 1 (chaperonin 10)0.061
Dcaf13DDB1 and CUL4 associated factor 130.047
Timm23translocase of inner mitochondrial membrane 23 homolog (yeast)0.039
Aimp1aminoacyl tRNA synthetase complex-interacting multifunctional protein 10.039
Psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.031
Mrpl16mitochondrial ribosomal protein L160.031
Psmc5protease (prosome, macropain) 26S subunit, ATPase 50.031
Rpl7aribosomal protein L7A0.030
Grpel1GrpE-like 1, mitochondrial0.030
Mrpl20mitochondrial ribosomal protein L200.027
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.026
Mrps18cmitochondrial ribosomal protein S18C0.025
Hprthypoxanthine guanine phosphoribosyl transferase0.023
Ufc1ubiquitin-fold modifier conjugating enzyme 10.023
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.022
Ndufa9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 90.021
Psme2proteasome (prosome, macropain) 28 subunit, beta0.020
Ppa1pyrophosphatase (inorganic) 10.019
Bud31BUD31 homolog (yeast)0.018
Arpc3actin related protein 2/3 complex, subunit 30.016
Psmb1proteasome (prosome, macropain) subunit, beta type 10.014
Snf8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.014
Nedd8neural precursor cell expressed, developmentally down-regulated gene 80.014
Pno1partner of NOB1 homolog (S. cerevisiae)0.014
Tbcbtubulin folding cofactor B0.013
Slmo2slowmo homolog 2 (Drosophila)0.012
Mmadhcmethylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria0.012
Rarsarginyl-tRNA synthetase0.012
Pdcd6programmed cell death 60.011
Sf3b5splicing factor 3b, subunit 50.011
Psme1proteasome (prosome, macropain) 28 subunit, alpha0.011
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.010
Stoml2stomatin (Epb7.2)-like 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PRE10Pre10p0.991
PUP3Pup3p0.973
PUP1Pup1p0.971
PRE2Pre2p0.954
PRE5Pre5p0.951
PRE6Pre6p0.949
PUP2Pup2p0.942
PRE7Pre7p0.911
SCL1Scl1p0.870
PRE8Pre8p0.832
PRE3Pre3p0.719
PRE1Pre1p0.647
PRE4Pre4p0.527
RPT1Rpt1p0.177
RPN7Rpn7p0.127
UMP1Ump1p0.113
RPN3Rpn3p0.090
RPN10Rpn10p0.084
ECM29Ecm29p0.063
RPN8Rpn8p0.056
PRE9Pre9p0.039
RPT6Rpt6p0.036
RPN9Rpn9p0.025
BLM10Blm10p0.025
RPN2Rpn2p0.024
SRD1Srd1p0.014
RPN11Rpn11p0.014
RPN13Rpn13p0.013
LEU2Leu2p0.013
YOL038C-Ahypothetical protein0.011
SPL2Spl2p0.011
YLR162Whypothetical protein0.011
RPT3Rpt3p0.010
MER1Mer1p0.010
ARP10Arp10p0.010
YLR264C-Ahypothetical protein0.010