The network for 'regulation of dna templated transcription initiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of dna templated transcription initiation

Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.

NameDescriptionProbabilityFunc Analog Organism
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.616
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.451
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.400
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.269
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.246
TBPTATA box binding protein0.238
SMAD4SMAD family member 40.220
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.205
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.175
NCOA6nuclear receptor coactivator 60.155
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.144
SP1Sp1 transcription factor0.102
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.099
SKILSKI-like oncogene0.092
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.084
TBX5T-box 50.082
CTR9Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.080
SMC1Astructural maintenance of chromosomes 1A0.070
HMGB2high mobility group box 20.067
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.064
CREBBPCREB binding protein0.060
TAF1TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa0.055
SMC3structural maintenance of chromosomes 30.054
RAD21RAD21 homolog (S. pombe)0.046
NCOA1nuclear receptor coactivator 10.044
NCOR1nuclear receptor corepressor 10.042
MED25mediator complex subunit 250.040
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.040
RB1retinoblastoma 10.038
SSRP1structure specific recognition protein 10.037
ESR1estrogen receptor 10.037
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.037
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.035
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.035
SMAD9SMAD family member 90.033
RBM25RNA binding motif protein 250.030
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.029
MKL1megakaryoblastic leukemia (translocation) 10.029
RXRAretinoid X receptor, alpha0.029
ARNTaryl hydrocarbon receptor nuclear translocator0.025
TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa0.024
BAZ1Abromodomain adjacent to zinc finger domain, 1A0.023
PSMD9proteasome (prosome, macropain) 26S subunit, non-ATPase, 90.021
NCOR2nuclear receptor corepressor 20.021
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.020
HMGA1high mobility group AT-hook 10.020
SIRT1sirtuin 10.020
NUP153nucleoporin 153kDa0.019
HNRNPA2B1heterogeneous nuclear ribonucleoprotein A2/B10.019
NBNnibrin0.018
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.017
HMGB1high mobility group box 10.017
DEKDEK oncogene0.016
HDAC3histone deacetylase 30.016
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.015
TRIM33tripartite motif containing 330.015
SMAD2SMAD family member 20.015
RSRC2arginine/serine-rich coiled-coil 20.014
DCP1BDCP1 decapping enzyme homolog B (S. cerevisiae)0.014
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.014
SNW1SNW domain containing 10.014
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa0.014
HTThuntingtin0.013
KAT2BK(lysine) acetyltransferase 2B0.013
PSIP1PC4 and SFRS1 interacting protein 10.013
WAPALwings apart-like homolog (Drosophila)0.013
SFPQsplicing factor proline/glutamine-rich0.012
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.012
E2F3E2F transcription factor 30.012
LBRlamin B receptor0.012
PRPF4BPRP4 pre-mRNA processing factor 4 homolog B (yeast)0.012
BCLAF1BCL2-associated transcription factor 10.012
SMAD3SMAD family member 30.011
KLHL24kelch-like 24 (Drosophila)0.011
C10orf18chromosome 10 open reading frame 180.011
ZNF518Azinc finger protein 518A0.011
CHD1chromodomain helicase DNA binding protein 10.011
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.011
SCAF8SR-related CTD-associated factor 80.011
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
mRpL49mitochondrial ribosomal protein L490.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pax2paired box gene 20.694
Fgf8fibroblast growth factor 80.659
Shhsonic hedgehog0.561
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.512
Gata4GATA binding protein 40.506
Gli2GLI-Kruppel family member GLI20.355
Wnt3awingless-related MMTV integration site 3A0.323
Gli3GLI-Kruppel family member GLI30.295
Pax8paired box gene 80.285
Hand2heart and neural crest derivatives expressed transcript 20.274
Sox9SRY-box containing gene 90.263
Nognoggin0.253
Ptpn11protein tyrosine phosphatase, non-receptor type 110.244
Rxraretinoid X receptor alpha0.228
Foxc1forkhead box C10.175
Lhx1LIM homeobox protein 10.167
Hand1heart and neural crest derivatives expressed transcript 10.160
Vax1ventral anterior homeobox containing gene 10.143
Fgfr2fibroblast growth factor receptor 20.140
Tbx1T-box 10.114
Wnt4wingless-related MMTV integration site 40.110
Barx2BarH-like homeobox 20.104
Pitx2paired-like homeodomain transcription factor 20.098
Hoxd13homeobox D130.090
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.087
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.087
Nkx6-1NK6 homeobox 10.087
Rargretinoic acid receptor, gamma0.083
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.079
Rarbretinoic acid receptor, beta0.077
Ror2receptor tyrosine kinase-like orphan receptor 20.075
Dkk1dickkopf homolog 1 (Xenopus laevis)0.068
Usp18ubiquitin specific peptidase 180.065
Wnt6wingless-related MMTV integration site 60.062
Cct7chaperonin containing Tcp1, subunit 7 (eta)0.061
Hoxa13homeobox A130.059
Hoxd11homeobox D110.058
Stat2signal transducer and activator of transcription 20.054
Lhx3LIM homeobox protein 30.053
Gdnfglial cell line derived neurotrophic factor0.049
Ctnnb1catenin (cadherin associated protein), beta 10.047
Gata6GATA binding protein 60.047
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.046
Tbx3T-box 30.045
Scaf11SR-related CTD-associated factor 110.044
Nr5a1nuclear receptor subfamily 5, group A, member 10.042
Mesp1mesoderm posterior 10.042
Gata5GATA binding protein 50.042
Trp63transformation related protein 630.040
Tbx5T-box 50.040
Emx2empty spiracles homolog 2 (Drosophila)0.040
Barx1BarH-like homeobox 10.039
Tbrachyury0.039
Foxc2forkhead box C20.039
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.038
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.038
Emx1empty spiracles homolog 1 (Drosophila)0.038
Uba7ubiquitin-like modifier activating enzyme 70.037
Otx2orthodenticle homolog 2 (Drosophila)0.037
Efna4ephrin A40.036
Lmx1aLIM homeobox transcription factor 1 alpha0.035
TapbpTAP binding protein0.034
En1engrailed 10.034
Suz12suppressor of zeste 12 homolog (Drosophila)0.033
Isg15ISG15 ubiquitin-like modifier0.033
Rararetinoic acid receptor, alpha0.033
Tgfb2transforming growth factor, beta 20.032
Zfpm2zinc finger protein, multitype 20.032
Pax1paired box gene 10.032
Otx1orthodenticle homolog 1 (Drosophila)0.032
Foxe1forkhead box E10.032
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.031
Fgf3fibroblast growth factor 30.031
Ntf3neurotrophin 30.031
Wnt2bwingless related MMTV integration site 2b0.030
Socs1suppressor of cytokine signaling 10.030
Irf7interferon regulatory factor 70.030
Pthlhparathyroid hormone-like peptide0.029
IhhIndian hedgehog0.029
Tbx2T-box 20.028
Bmp7bone morphogenetic protein 70.028
Nkx3-2NK3 homeobox 20.028
Pitx1paired-like homeodomain transcription factor 10.027
Klklotho0.027
Irgm1immunity-related GTPase family M member 10.027
Amhanti-Mullerian hormone0.026
Col2a1collagen, type II, alpha 10.026
Arandrogen receptor0.026
Batf3basic leucine zipper transcription factor, ATF-like 30.025
Gli1GLI-Kruppel family member GLI10.025
Tcf21transcription factor 210.024
Lmx1bLIM homeobox transcription factor 1 beta0.024
Igtpinterferon gamma induced GTPase0.023
Wnt10bwingless related MMTV integration site 10b0.023
Cdx1caudal type homeobox 10.023
Hmx3H6 homeobox 30.023
Bmpr1abone morphogenetic protein receptor, type 1A0.022
Six5sine oculis-related homeobox 5 homolog (Drosophila)0.022
Foxa2forkhead box A20.022
Efnb2ephrin B20.022
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.089
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.040
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.034
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.020
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SPT16Spt16p0.820
NGG1Ngg1p0.362
SPT5Spt5p0.300
RPN2Rpn2p0.283
RPT6Rpt6p0.267
RPN1Rpn1p0.232
CHD1Chd1p0.227
CTR9Ctr9p0.197
MOT1Mot1p0.191
RSC4Rsc4p0.175
SPT6Spt6p0.170
RPT2Rpt2p0.153
RTF1Rtf1p0.147
RPN6Rpn6p0.119
RPT1Rpt1p0.118
TRA1Tra1p0.111
RPT4Rpt4p0.108
TAF6Taf6p0.106
BUR6Bur6p0.103
RFA1Rfa1p0.101
SKI3Ski3p0.089
RPN9Rpn9p0.079
SET2Set2p0.075
RPN7Rpn7p0.070
TAF12Taf12p0.064
TIF4632Tif4632p0.060
LSM4Lsm4p0.059
SUS1Sus1p0.058
HHT1Hht1p0.057
RAD23Rad23p0.057
CKA1Cka1p0.056
CKB1Ckb1p0.051
POB3Pob3p0.050
DCP1Dcp1p0.049
ADA2Ada2p0.045
IOC3Ioc3p0.045
WWM1Wwm1p0.043
INO80Ino80p0.042
SRD1Srd1p0.041
TAF5Taf5p0.040
ECM29Ecm29p0.040
LEU2Leu2p0.039
YLR264C-Ahypothetical protein0.038
TFA1Tfa1p0.037
RSC8Rsc8p0.037
YLR162Whypothetical protein0.035
TFG1Tfg1p0.035
YOL038C-Ahypothetical protein0.035
STH1Sth1p0.035
RPN3Rpn3p0.034
HXT3Hxt3p0.033
BEM2Bem2p0.033
ESF1Esf1p0.032
YIL151Chypothetical protein0.032
MF(ALPHA)2Mf(alpha)2p0.032
TAF10Taf10p0.032
MER1Mer1p0.032
SWI1Swi1p0.032
ARP10Arp10p0.031
SPL2Spl2p0.031
RPN10Rpn10p0.030
ARG8Arg8p0.030
URA3Ura3p0.030
RPT5Rpt5p0.030
SGT2Sgt2p0.030
YLR419Whypothetical protein0.029
DLS1Dls1p0.029
CHA1Cha1p0.028
SEM1Sem1p0.028
YGR017Whypothetical protein0.028
YPR157Whypothetical protein0.028
YAR068Whypothetical protein0.028
YLR042Chypothetical protein0.027
TFG2Tfg2p0.027
HOHop0.027
MF(ALPHA)1Mf(alpha)1p0.027
PRS2Prs2p0.026
ATP6Atp6p0.026
ITC1Itc1p0.026
SCM4Scm4p0.025
MCM6Mcm6p0.025
HPF1Hpf1p0.025
YBR013Chypothetical protein0.024
CUP1-1Cup1-1p0.024
AUA1Aua1p0.024
IOC2Ioc2p0.024
FMT1Fmt1p0.024
AQY2Aqy2p0.024
ZPS1Zps1p0.024
PHM6Phm6p0.023
REB1Reb1p0.023
RSC58Rsc58p0.023
YOL013W-Ahypothetical protein0.023
PRE10Pre10p0.022
DIC1Dic1p0.022
TYE7Tye7p0.022
LEO1Leo1p0.021
OPT2Opt2p0.021
RCO1Rco1p0.021
SPT15Spt15p0.021