The network for 'saliva secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

saliva secretion

The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.

NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 20.999
FGF1fibroblast growth factor 1 (acidic)0.791
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.305
FGFR1fibroblast growth factor receptor 10.172
PKD2polycystic kidney disease 2 (autosomal dominant)0.045
ADAMTSL4ADAMTS-like 40.032
FGF8fibroblast growth factor 8 (androgen-induced)0.020
TACR1tachykinin receptor 10.016
FAM107Afamily with sequence similarity 107, member A0.013
TAC1tachykinin, precursor 10.011
FGF10fibroblast growth factor 100.011
FGFR3fibroblast growth factor receptor 30.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Chrm1cholinergic receptor, muscarinic 1, CNS0.119
Cckbrcholecystokinin B receptor0.072
Oprd1opioid receptor, delta 10.060
Rgs9regulator of G-protein signaling 90.045
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.038
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.032
Htr45 hydroxytryptamine (serotonin) receptor 40.030
Muskmuscle, skeletal, receptor tyrosine kinase0.025
Grprgastrin releasing peptide receptor0.025
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.024
Sez6seizure related gene 60.024
Cgaglycoprotein hormones, alpha subunit0.023
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.022
Drd2dopamine receptor D20.022
Zp1zona pellucida glycoprotein 10.022
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.021
Rit2Ras-like without CAAX 20.021
Dlg2discs, large homolog 2 (Drosophila)0.021
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.020
Cntn1contactin 10.019
Syn2synapsin II0.019
Cntn3contactin 30.018
Slc22a12solute carrier family 22 (organic anion/cation transporter), member 120.018
Cnr1cannabinoid receptor 1 (brain)0.017
Srcin1SRC kinase signaling inhibitor 10.017
Hrh1histamine receptor H10.017
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.016
Aff2AF4/FMR2 family, member 20.016
Gpr83G protein-coupled receptor 830.016
Rgs4regulator of G-protein signaling 40.015
Col4a3collagen, type IV, alpha 30.015
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.015
Cntn4contactin 40.014
Gabrg3gamma-aminobutyric acid (GABA) A receptor, subunit gamma 30.014
Shbgsex hormone binding globulin0.014
Kcnq2potassium voltage-gated channel, subfamily Q, member 20.013
Cacna1ecalcium channel, voltage-dependent, R type, alpha 1E subunit0.012
Neto1neuropilin (NRP) and tolloid (TLL)-like 10.012
Sftpcsurfactant associated protein C0.012
Pgrprogesterone receptor0.012
Gja5gap junction protein, alpha 50.012
Rgs8regulator of G-protein signaling 80.012
Prlhrprolactin releasing hormone receptor0.011
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.011
Drd3dopamine receptor D30.011
Grin2cglutamate receptor, ionotropic, NMDA2C (epsilon 3)0.010
Esr2estrogen receptor 2 (beta)0.010
Grem2gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.429
Olr1500olfactory receptor 15000.410
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.373
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.313
Insrrinsulin receptor-related receptor0.284
Fgf14fibroblast growth factor 140.268
Grm1glutamate receptor, metabotropic 10.196
Fgf7fibroblast growth factor 70.195
Col10a1collagen, type X, alpha 10.189
Syt8synaptotagmin VIII0.185
Mmp10matrix metallopeptidase 100.185
Cntn3contactin 3 (plasmacytoma associated)0.171
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.170
Slc8a3solute carrier family 8 (sodium/calcium exchanger), member 30.168
Kcng3potassium voltage-gated channel, subfamily G, member 30.168
Cckarcholecystokinin A receptor0.142
Il10interleukin 100.141
Fibcd1fibrinogen C domain containing 10.137
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.132
Crhbpcorticotropin releasing hormone binding protein0.130
Fosl1fos-like antigen 10.130
Pthparathyroid hormone0.129
Necab1N-terminal EF-hand calcium binding protein 10.123
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.121
Magmyelin-associated glycoprotein0.120
Chrna7cholinergic receptor, nicotinic, alpha 70.114
Fgf2fibroblast growth factor 20.113
Egr3early growth response 30.110
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.110
Csf1colony stimulating factor 1 (macrophage)0.108
Htr2a5-hydroxytryptamine (serotonin) receptor 2A0.107
Accn1amiloride-sensitive cation channel 1, neuronal0.104
Ccbp2chemokine binding protein 20.102
Gabra5gamma-aminobutyric acid (GABA) A receptor, alpha 50.100
Vipvasoactive intestinal peptide0.099
Dio2deiodinase, iodothyronine, type II0.098
Scn10asodium channel, voltage-gated, type X, alpha subunit0.096
Kalrnkalirin, RhoGEF kinase0.095
Adam3aADAM metallopeptidase domain 3A (cyritestin 1)0.094
Adam2ADAM metallopeptidase domain 20.093
Chrm1cholinergic receptor, muscarinic 10.090
Htr1f5-hydroxytryptamine (serotonin) receptor 1F0.090
Sstr1somatostatin receptor 10.090
Prol1proline rich, lacrimal 10.087
Gpr12G protein-coupled receptor 120.086
Arandrogen receptor0.085
Kcnmb1potassium large conductance calcium-activated channel, subfamily M, beta member 10.085
Il13interleukin 130.084
Mas1MAS1 oncogene0.082
Toretrispanning orphan0.081
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.080
Hdgfl1hepatoma derived growth factor-like 10.078
Calcrcalcitonin receptor0.074
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.073
Gad2glutamate decarboxylase 20.073
Trpc4transient receptor potential cation channel, subfamily C, member 40.073
Zp1zona pellucida glycoprotein 1 (sperm receptor)0.073
Chrm5cholinergic receptor, muscarinic 50.073
Adam7ADAM metallopeptidase domain 70.073
Necab2N-terminal EF-hand calcium binding protein 20.073
Srysex determining region Y0.072
Fam38bfamily with sequence similarity 38, member B0.071
Tas2r126taste receptor, type 2, member 1260.071
Spt1salivary protein 10.069
Trhthyrotropin releasing hormone0.065
Npy5rneuropeptide Y receptor Y50.064
Reg3aregenerating islet-derived 3 alpha0.064
N5DNA binding protein N50.063
CartptCART prepropeptide0.062
Olr1078olfactory receptor 10780.062
Cpa3carboxypeptidase A3, mast cell0.061
Olr1641olfactory receptor 16410.061
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.060
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.059
Plcd4phospholipase C, delta 40.059
Kcnc2potassium voltage gated channel, Shaw-related subfamily, member 20.059
Kcnk13potassium channel, subfamily K, member 130.059
Htr75-hydroxytryptamine (serotonin) receptor 70.059
Arnt2aryl hydrocarbon receptor nuclear translocator 20.059
Aqp5aquaporin 50.058
Cd40lgCD40 ligand0.058
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.058
Chrnb3cholinergic receptor, nicotinic, beta 30.057
LOC689154hypothetical protein LOC6891540.057
Adam5a disintegrin and metallopeptidase domain 50.056
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.056
Kcnab1potassium voltage-gated channel, shaker-related subfamily, beta member 10.056
Nmbrneuromedin B receptor0.055
Tnfsf4tumor necrosis factor (ligand) superfamily, member 40.055
Tacr2tachykinin receptor 20.054
Mfrpmembrane frizzled-related protein0.054
Cacng4calcium channel, voltage-dependent, gamma subunit 40.053
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.053
Vom2r53vomeronasal 2 receptor, 530.053
Tas2r123taste receptor, type 2, member 1230.052
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism