The network for 'central nervous system projection neuron axonogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

central nervous system projection neuron axonogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.

NameDescriptionProbabilityFunc Analog Organism
PELP1proline, glutamate and leucine rich protein 10.734
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.626
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.463
SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)0.351
DUSP1dual specificity phosphatase 10.222
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.197
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.178
SENP1SUMO1/sentrin specific peptidase 10.155
USPL1ubiquitin specific peptidase like 10.155
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.146
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.140
PTPRNprotein tyrosine phosphatase, receptor type, N0.117
DISC1disrupted in schizophrenia 10.099
CPEcarboxypeptidase E0.095
RANGAP1Ran GTPase activating protein 10.087
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.078
SAE1SUMO1 activating enzyme subunit 10.077
GRB7growth factor receptor-bound protein 70.070
MAPKAPK3mitogen-activated protein kinase-activated protein kinase 30.069
MAPK14mitogen-activated protein kinase 140.063
TCEAL5transcription elongation factor A (SII)-like 50.058
CCT8chaperonin containing TCP1, subunit 8 (theta)0.057
PFDN1prefoldin subunit 10.056
HDAC3histone deacetylase 30.054
NTN1netrin 10.052
WDR18WD repeat domain 180.046
PKM2pyruvate kinase, muscle0.046
PBX1pre-B-cell leukemia homeobox 10.037
CLIP1CAP-GLY domain containing linker protein 10.037
MYO10myosin X0.035
ATN1atrophin 10.034
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.033
RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.032
PPP2R2Cprotein phosphatase 2, regulatory subunit B, gamma0.032
NR4A3nuclear receptor subfamily 4, group A, member 30.031
NFIAnuclear factor I/A0.030
SCAND1SCAN domain containing 10.030
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.029
CDH2cadherin 2, type 1, N-cadherin (neuronal)0.028
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.028
TEX10testis expressed 100.027
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein0.025
CXXC1CXXC finger protein 10.025
RDH11retinol dehydrogenase 11 (all-trans/9-cis/11-cis)0.023
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0.023
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.023
DUSP3dual specificity phosphatase 30.022
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.021
PCDH17protocadherin 170.021
UBE3Aubiquitin protein ligase E3A0.021
PIAS4protein inhibitor of activated STAT, 40.021
PPP4R1protein phosphatase 4, regulatory subunit 10.021
DEF6differentially expressed in FDCP 6 homolog (mouse)0.020
ZNF219zinc finger protein 2190.020
EGR3early growth response 30.020
USP39ubiquitin specific peptidase 390.020
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.020
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.020
LTBP2latent transforming growth factor beta binding protein 20.019
SOX11SRY (sex determining region Y)-box 110.019
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.019
MAP2K1mitogen-activated protein kinase kinase 10.019
UBE2Mubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)0.019
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.019
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.019
DAPK1death-associated protein kinase 10.018
USP21ubiquitin specific peptidase 210.018
MAZMYC-associated zinc finger protein (purine-binding transcription factor)0.018
SPARCL1SPARC-like 1 (hevin)0.018
EDNRAendothelin receptor type A0.018
LMO2LIM domain only 2 (rhombotin-like 1)0.018
RAB14RAB14, member RAS oncogene family0.018
MEIS2Meis homeobox 20.018
GRB10growth factor receptor-bound protein 100.017
COTL1coactosin-like 1 (Dictyostelium)0.017
LAS1LLAS1-like (S. cerevisiae)0.017
NR2F1nuclear receptor subfamily 2, group F, member 10.017
FLRT2fibronectin leucine rich transmembrane protein 20.017
GNB2guanine nucleotide binding protein (G protein), beta polypeptide 20.017
SFRP1secreted frizzled-related protein 10.017
COL3A1collagen, type III, alpha 10.017
LPHN3latrophilin 30.017
PHF17PHD finger protein 170.017
SP100SP100 nuclear antigen0.016
SNRNP40small nuclear ribonucleoprotein 40kDa (U5)0.016
PRRX1paired related homeobox 10.016
GIT2G protein-coupled receptor kinase interacting ArfGAP 20.016
MFAP4microfibrillar-associated protein 40.016
ELK1ELK1, member of ETS oncogene family0.016
ARRB2arrestin, beta 20.016
FAM82A2family with sequence similarity 82, member A20.016
WDR48WD repeat domain 480.016
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.016
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.016
TNRC6Btrinucleotide repeat containing 6B0.016
COL11A1collagen, type XI, alpha 10.015
MEN1multiple endocrine neoplasia I0.015
FBLN1fibulin 10.015
MAP2K2mitogen-activated protein kinase kinase 20.015
KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.015
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ptch2patched 20.930
gli1GLI-Kruppel family member 10.890
evx1even-skipped homeobox 10.754
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.739
dbx1adeveloping brain homeobox 1a0.692
slit3slit (Drosophila) homolog 30.645
sfrp5secreted frizzled-related protein 50.531
eng1aengrailed 1a0.499
nr4a2bnuclear receptor subfamily 4, group A, member 2b0.448
lhx2bLIM homeobox 2b0.432
coe2coe20.412
wnt8bwingless-type MMTV integration site family, member 8b0.357
robo2roundabout homolog 20.321
arxaristaless related homeobox0.298
pou3f3bPOU class 3 homeobox 3b0.286
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.286
mapk1mitogen-activated protein kinase 10.283
dpysl2bdihydropyrimidinase-like 2b0.202
foxd3forkhead box D30.183
six3bsine oculis homeobox homolog 3b0.180
bocbrother of CDO0.162
epha4beph receptor A4b0.158
tbx1T-box 10.158
nr2e1nuclear receptor subfamily 2, group E, member 10.156
dlx2adistal-less homeobox gene 2a0.150
olig2oligodendrocyte lineage transcription factor 20.147
shhasonic hedgehog a0.130
barhl2BarH-like 20.126
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.123
ascl1aachaete-scute complex-like 1a (Drosophila)0.116
mapk3mitogen-activated protein kinase 30.116
pax3apaired box gene 3a0.112
tbx2bT-box 2b0.109
phox2apaired-like homeobox 2a0.105
sox21bSRY-box containing gene 21 b0.090
fgf8bfibroblast growth factor 8 b0.087
dladeltaA0.086
nkd1naked cuticle homolog 1 (Drosophila)0.084
sim1asingle-minded homolog 1a (Drosophila)0.084
nrp2bneuropilin 2b0.084
eng2aengrailed 2a0.083
sumo1SMT3 suppressor of mif two 3 homolog 1 (yeast)0.083
eng2bengrailed 2b0.082
ntn2netrin 20.081
fstl1bfollistatin-like 1b0.076
foxp2forkhead box P20.070
pou3f1POU class 3 homeobox 10.068
col14a1collagen, type XIV, alpha 10.067
gria3aglutamate receptor, ionotropic, AMPA 3a0.066
gria2aglutamate receptor, ionotropic, AMPA 2a0.065
pax6apaired box gene 6a0.062
pcdh17protocadherin 170.062
h3f3aH3 histone, family 3A0.061
tac1tachykinin 10.061
ntn1anetrin 1a0.060
cntn2contactin 20.058
neurog1neurogenin 10.058
nrp2aneuropilin 2a0.056
lhx9LIM homeobox 90.056
prrx1apaired related homeobox 1a0.054
angpt1angiopoietin 10.053
fezf2FEZ family zinc finger 20.053
nrg2aneuregulin 2a0.052
myo7aamyosin VIIAa0.052
fgfr1bfibroblast growth factor receptor 1b0.051
emx2empty spiracles homeobox 20.051
scrt2scratch homolog 2, zinc finger protein (Drosophila)0.049
gli2bGLI-Kruppel family member GLI2b0.049
nrp1bneuropilin 1b0.049
casp3acaspase 3, apoptosis-related cysteine protease a0.049
slit2slit (Drosophila) homolog 20.048
ptch1patched 10.048
capns1bcalpain, small subunit 1 b0.048
cd99l2CD99 antigen-like 20.046
gria3bglutamate receptor, ionotrophic, AMPA 3b0.046
olfm2olfactomedin 20.045
gad1bglutamate decarboxylase 1b0.044
sox9aSRY-box containing gene 9a0.042
si:dkey-24g18.2si:dkey-24g18.20.042
nrg1neuregulin 10.042
gngt2aguanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a0.042
ascl1bachaete-scute complex-like 1b (Drosophila)0.042
wnt1wingless-type MMTV integration site family, member 10.041
zic1zic family member 1 (odd-paired homolog, Drosophila)0.039
hgfahepatocyte growth factor a0.039
slit1bslit homolog 1b (Drosophila)0.039
sst1.1somatostatin 1, tandem duplicate 10.037
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.036
adcyap1badenylate cyclase activating polypeptide 1b0.036
sox10SRY-box containing gene 100.035
gria1aglutamate receptor, ionotropic, AMPA 1a0.035
scrt1ascratch homolog 1, zinc finger protein a (Drosophila)0.035
nr2f1bnuclear receptor subfamily 2, group F, member 1b0.034
slit1aslit homolog 1a (Drosophila)0.034
mapk4mitogen-activated protein kinase 40.034
esrrgaestrogen-related receptor gamma a0.034
fkbp10FK506 binding protein 100.033
tcf4transcription factor 40.033
gria4bglutamate receptor, ionotropic, AMPA 4b0.033
oprd1bopioid receptor, delta 1b0.033
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
roboroundabout0.992
lealeak0.925
commcommissureless0.761
cicubitus interruptus0.459
frafrazzled0.371
tutlturtle0.294
DscamDown syndrome cell adhesion molecule0.254
slislit0.232
hhhedgehog0.218
wgwingless0.213
ph-ppolyhomeotic proximal0.146
enengrailed0.132
ptcpatched0.126
Sema-1aCG18405 gene product from transcript CG18405-RD0.113
unc-5CG8166 gene product from transcript CG8166-RA0.106
EphEph receptor tyrosine kinase0.087
dockdreadlocks0.083
trntartan0.077
spispitz0.074
CapsCalcium activated protein for secretion0.073
CadNCadherin-N0.066
eyaeyes absent0.065
Ptp69DProtein tyrosine phosphatase 69D0.056
stanstarry night0.055
enaenabled0.053
gcmglial cells missing0.051
trioCG18214 gene product from transcript CG18214-RA0.050
ococelliless0.042
sqzsqueeze0.041
NetBNetrin-B0.039
Trim9CG31721 gene product from transcript CG31721-RB0.039
Rac1CG2248 gene product from transcript CG2248-RA0.039
lolalongitudinals lacking0.035
phopleiohomeotic0.033
robo3CG5423 gene product from transcript CG5423-RA0.032
hkbhuckebein0.030
EphrinCG1862 gene product from transcript CG1862-RA0.030
jingCG9397 gene product from transcript CG9397-RI0.029
MicalMolecule interacting with CasL0.029
drlderailed0.028
endoAendophilin A0.027
Taf1TBP-associated factor 10.026
foifear-of-intimacy0.024
grngrain0.024
Wnt5Wnt oncogene analog 50.023
midmidline0.022
tlltailless0.022
NetANetrin-A0.022
HemHEM-protein0.022
simsingle-minded0.021
invinvected0.021
Nedd4CG42279 gene product from transcript CG42279-RJ0.021
cv-ccrossveinless c0.020
emsempty spiracles0.020
CaMKIICalcium/calmodulin-dependent protein kinase II0.020
kuzkuzbanian0.020
argosCG4531 gene product from transcript CG4531-RA0.019
Wnt4Wnt oncogene analog 40.018
SnooSno oncogene0.018
knknot0.018
staistathmin0.018
Stat92ESignal-transducer and activator of transcription protein at 92E0.018
eyeyeless0.017
zfh2Zn finger homeodomain 20.017
gsbgooseberry0.017
salmspalt major0.017
brkbrinker0.017
SoxNSoxNeuro0.017
smosmoothened0.016
slp1sloppy paired 10.015
prosprospero0.015
rapretina aberrant in pattern0.015
nkdnaked cuticle0.015
osoutstretched0.014
araaraucan0.014
Sra-1specifically Rac1-associated protein 10.014
pblpebble0.014
tuptailup0.014
beat-Iabeaten path Ia0.014
form3formin 30.013
Hr51Hormone receptor 510.013
CycACyclin A0.013
otkoff-track0.012
tgotango0.012
chicchickadee0.012
Nrx-1Neurexin 10.012
babobaboon0.012
bowlbrother of odd with entrails limited0.012
Sema-2aCG4700 gene product from transcript CG4700-RC0.012
nvynervy0.011
vflvielfaltig0.011
nerfin-1nervous fingers 10.011
beta-Specbeta Spectrin0.011
LamLamin0.011
Ino80CG31212 gene product from transcript CG31212-RA0.010
DDichaete0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gli3GLI-Kruppel family member GLI31.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Epha4Eph receptor A41.000
Pax6paired box gene 60.999
Gli2GLI-Kruppel family member GLI20.999
Efnb2ephrin B20.998
Emx1empty spiracles homolog 1 (Drosophila)0.998
Ephb2Eph receptor B20.998
Shhsonic hedgehog0.997
Slit2slit homolog 2 (Drosophila)0.991
Robo1roundabout homolog 1 (Drosophila)0.991
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.990
Fgfr2fibroblast growth factor receptor 20.985
Unc5cunc-5 homolog C (C. elegans)0.982
Rargretinoic acid receptor, gamma0.981
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.973
Nfibnuclear factor I/B0.968
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.968
Dccdeleted in colorectal carcinoma0.963
Sox2SRY-box containing gene 20.958
Pax2paired box gene 20.954
Tgfb2transforming growth factor, beta 20.953
Foxc1forkhead box C10.952
Emx2empty spiracles homolog 2 (Drosophila)0.952
Pax3paired box gene 30.943
Smosmoothened homolog (Drosophila)0.942
Pbx1pre B-cell leukemia transcription factor 10.941
Tcfap2atranscription factor AP-2, alpha0.941
Sox9SRY-box containing gene 90.923
Gbx2gastrulation brain homeobox 20.922
Foxc2forkhead box C20.903
Fgf8fibroblast growth factor 80.896
Fgfr1fibroblast growth factor receptor 10.882
Foxg1forkhead box G10.875
Efnb1ephrin B10.855
Pitx2paired-like homeodomain transcription factor 20.840
Slit3slit homolog 3 (Drosophila)0.818
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.786
Jag1jagged 10.755
Tbx1T-box 10.744
Rarbretinoic acid receptor, beta0.737
Nrp1neuropilin 10.735
Rararetinoic acid receptor, alpha0.696
Neurod1neurogenic differentiation 10.689
Fgf10fibroblast growth factor 100.662
Meis2Meis homeobox 20.657
Eya1eyes absent 1 homolog (Drosophila)0.651
Vangl2vang-like 2 (van gogh, Drosophila)0.646
Dlx5distal-less homeobox 50.642
Ly6hlymphocyte antigen 6 complex, locus H0.633
En1engrailed 10.622
Robo2roundabout homolog 2 (Drosophila)0.617
Lmx1aLIM homeobox transcription factor 1 alpha0.580
Ednraendothelin receptor type A0.578
Msx1homeobox, msh-like 10.544
Chrdchordin0.542
Chd7chromodomain helicase DNA binding protein 70.530
Isl1ISL1 transcription factor, LIM/homeodomain0.528
Bocbiregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein0.527
Sox11SRY-box containing gene 110.520
Wnt5awingless-related MMTV integration site 5A0.481
Neurog2neurogenin 20.474
Lmx1bLIM homeobox transcription factor 1 beta0.462
Sema5bsema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B0.456
Lhx1LIM homeobox protein 10.451
Otx1orthodenticle homolog 1 (Drosophila)0.445
NynrinNYN domain and retroviral integrase containing0.442
Itga3integrin alpha 30.423
Gata4GATA binding protein 40.422
Arhgef12Rho guanine nucleotide exchange factor (GEF) 120.410
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.404
Tbx3T-box 30.403
Dcxdoublecortin0.389
Nr2f1nuclear receptor subfamily 2, group F, member 10.384
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.363
Ntn1netrin 10.358
Rhorhodopsin0.355
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.353
Nfianuclear factor I/A0.345
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.338
Ece1endothelin converting enzyme 10.337
Chrnb4cholinergic receptor, nicotinic, beta polypeptide 40.335
Zfpm2zinc finger protein, multitype 20.326
Nr0b1nuclear receptor subfamily 0, group B, member 10.325
Bmp7bone morphogenetic protein 70.314
Hoxa1homeobox A10.298
Nognoggin0.297
Efna2ephrin A20.289
Msx2homeobox, msh-like 20.283
Egr1early growth response 10.274
Zeb1zinc finger E-box binding homeobox 10.274
En2engrailed 20.272
Onecut1one cut domain, family member 10.269
FosFBJ osteosarcoma oncogene0.264
Isl2insulin related protein 2 (islet 2)0.263
St8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.253
Auts2autism susceptibility candidate 20.252
Bhlhe22basic helix-loop-helix family, member e220.249
Lhx9LIM homeobox protein 90.244
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.242
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism