The network for 'electron transport chain' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

electron transport chain

A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.

NameDescriptionProbabilityFunc Analog Organism
NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)0.512
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.433
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.358
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.355
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.315
UQCRC2ubiquinol-cytochrome c reductase core protein II0.247
NDUFS7NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)0.172
NDUFS8NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)0.162
NDUFS2NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)0.159
NDUFV2NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa0.133
HDAC1histone deacetylase 10.098
DLDdihydrolipoamide dehydrogenase0.090
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.067
COX6Ccytochrome c oxidase subunit VIc0.051
NDUFB5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa0.049
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.047
UQCRC1ubiquinol-cytochrome c reductase core protein I0.041
NDUFV1NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa0.038
NDUFA2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa0.030
SAMM50sorting and assembly machinery component 50 homolog (S. cerevisiae)0.029
ATP5C1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.027
COX5Acytochrome c oxidase subunit Va0.025
ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.024
ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B10.023
SMN1survival of motor neuron 1, telomeric0.023
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.019
COX7Bcytochrome c oxidase subunit VIIb0.019
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.019
DECR12,4-dienoyl CoA reductase 1, mitochondrial0.018
NDUFA9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa0.018
NDUFB1NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa0.015
PPARGperoxisome proliferator-activated receptor gamma0.014
ACADMacyl-CoA dehydrogenase, C-4 to C-12 straight chain0.014
ESRRGestrogen-related receptor gamma0.014
MRPL23mitochondrial ribosomal protein L230.013
FBXO7F-box protein 70.013
SNCAIPsynuclein, alpha interacting protein0.012
MDH1malate dehydrogenase 1, NAD (soluble)0.012
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 50.012
PDHXpyruvate dehydrogenase complex, component X0.011
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
F29B9.11Protein F29B9.110.155
cts-1Protein CTS-10.141
F58F12.1Protein F58F12.10.121
nuo-5Protein NUO-50.078
ucr-1Protein UCR-10.074
nuo-2Protein NUO-20.070
CELE_Y67H2A.5Protein Y67H2A.50.053
atp-5Protein ATP-50.045
clpp-1Protein CLPP-10.044
isp-1Protein ISP-10.043
C30H6.7Protein C30H6.70.038
ard-1Protein ARD-10.026
F36A2.7Protein F36A2.70.024
ucr-2.2Protein UCR-2.20.024
F44E7.5Protein F44E7.50.023
ZK809.3Protein ZK809.30.023
CELE_F59C6.5Protein F59C6.50.022
immt-1Protein IMMT-10.020
F45H10.2Protein F45H10.20.019
B0491.5Protein B0491.50.019
C34B2.8Protein C34B2.80.019
idhb-1Protein IDHB-10.017
prdx-3Protein PRDX-30.017
F42G8.10Protein F42G8.100.016
nuo-4Protein NUO-40.014
idha-1Protein IDHA-10.014
pdhb-1Protein PDHB-10.014
rpia-1Protein RPIA-10.014
dars-1Protein DARS-10.014
cyc-2.1Protein CYC-2.10.013
kin-14Protein KIN-140.013
R53.4Protein R53.40.013
tkt-1Protein TKT-10.012
mut-7Protein MUT-70.012
CELE_ZK637.2Protein ZK637.20.012
dao-5Protein DAO-50.012
syp-4Protein SYP-40.012
ncx-2Protein NCX-20.011
CELE_Y69A2AR.18Protein Y69A2AR.180.011
mrps-14Protein MRPS-140.011
pbs-6Protein PBS-60.010
F37C12.3Protein F37C12.30.010
aipl-1Protein AIPL-10.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.914
etfaelectron-transfer-flavoprotein, alpha polypeptide0.834
sdhbsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.623
uqcrc2bubiquinol-cytochrome c reductase core protein IIb0.585
ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)0.575
zgc:73198zgc:731980.568
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.519
ndufb8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 80.393
pdhbpyruvate dehydrogenase (lipoamide) beta0.392
uqcrc1ubiquinol-cytochrome c reductase core protein I0.382
zgc:66391zgc:663910.378
ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.355
ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.323
aco2aconitase 2, mitochondrial0.309
sucla2succinate-CoA ligase, ADP-forming, beta subunit0.307
zgc:64133zgc:641330.282
ndufa9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 90.270
aldh7a1aldehyde dehydrogenase 7 family, member A10.270
dlstdihydrolipoamide S-succinyltransferase0.264
phbprohibitin0.251
pdha1apyruvate dehydrogenase (lipoamide) alpha 1a0.248
uqcrc2aubiquinol-cytochrome c reductase core protein IIa0.222
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.208
lrpprcleucine-rich PPR-motif containing0.190
ivdisovaleryl Coenzyme A dehydrogenase0.182
acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.177
ndufa8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 80.177
slc25a11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.166
dldhdihydrolipoamide dehydrogenase0.163
acaa2acetyl-CoA acyltransferase 20.160
acadlacyl-Coenzyme A dehydrogenase, long chain0.149
atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.139
slc25a3bsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b0.138
atp5gATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)0.131
uqcrbubiquinol-cytochrome c reductase binding protein0.126
ndufb9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 90.122
cox8acytochrome c oxidase subunit 8a0.104
suclg1succinate-CoA ligase, GDP-forming, alpha subunit0.104
zgc:111961zgc:1119610.098
immtinner membrane protein, mitochondrial (mitofilin)0.086
ndufa6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 60.084
sdhcsuccinate dehydrogenase complex, subunit C, integral membrane protein0.073
cyc1cytochrome c-10.071
prdx3peroxiredoxin 30.071
zgc:158138zgc:1581380.070
cox4i1cytochrome c oxidase subunit IV isoform 10.068
slc2a12solute carrier family 2 (facilitated glucose transporter), member 120.061
zgc:77820zgc:778200.058
idh2isocitrate dehydrogenase 2 (NADP+), mitochondrial0.057
extl3exostoses (multiple)-like 30.056
cox7ccytochrome c oxidase, subunit VIIc0.054
gbasglioblastoma amplified sequence0.052
sarsseryl-tRNA synthetase0.052
atp5c1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.051
chchd10coiled-coil-helix-coiled-coil-helix domain containing 100.047
zgc:112340zgc:1123400.046
ldhbalactate dehydrogenase Ba0.045
zgc:73329zgc:733290.045
kdm4blysine (K)-specific demethylase 4B0.044
gpx4aglutathione peroxidase 4a0.044
hsp90a.2heat shock protein 90-alpha 20.043
got2aglutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2)0.041
sb:cb592sb:cb5920.039
ATP8ATP synthase 80.039
pccbpropionyl Coenzyme A carboxylase, beta polypeptide0.037
sps2selenophosphate synthetase 20.037
nlgn1neuroligin 10.036
mdh1amalate dehydrogenase 1a, NAD (soluble)0.035
sod1superoxide dismutase 1, soluble0.035
tpi1btriosephosphate isomerase 1b0.034
ndufab1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 10.034
pgam1bphosphoglycerate mutase 1b0.034
slco1d1solute carrier organic anion transporter family, member 1D10.033
zgc:92030zgc:920300.032
eno3enolase 3, (beta, muscle)0.032
agpat31-acylglycerol-3-phosphate O-acyltransferase 30.031
cnp2',3'-cyclic nucleotide 3' phosphodiesterase0.030
slc25a12solute carrier family 25 (mitochondrial carrier, Aralar), member 120.030
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.030
zgc:100908zgc:1009080.030
arfip2bADP-ribosylation factor interacting protein 2b0.029
atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.029
mibmind bomb0.029
tardbpTAR DNA binding protein0.029
ndufb6NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 60.028
atp5lATP synthase, H+ transporting, mitochondrial F0 complex, subunit g0.028
slc45a2solute carrier family 45, member 20.028
abcd3aATP-binding cassette, sub-family D (ALD), member 3a0.026
surf4lsurfeit gene 4, like0.026
zgc:92631zgc:926310.026
cox7a2cytochrome c oxidase, subunit VIIa 20.025
phf2PHD finger protein 20.025
atp5f1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 10.025
aldh2baldehyde dehydrogenase 2b0.024
amtaminomethyltransferase0.023
tp53tumor protein p530.023
ndufb4NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 40.023
dnm1ldynamin 1-like0.023
ocrloculocerebrorenal syndrome of Lowe0.022
fxr1fragile X mental retardation, autosomal homolog 10.022
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
porinCG6647 gene product from transcript CG6647-RA0.264
ND75NADH:ubiquinone reductase 75kD subunit precursor0.195
ATPsyn-bATP synthase, subunit b0.176
Sod2Superoxide dismutase 2 (Mn)0.170
l(2)35Dilethal (2) 35Di0.115
SdhBSuccinate dehydrogenase B0.111
CG6020CG6020 gene product from transcript CG6020-RA0.100
Pink1PTEN-induced putative kinase 10.062
ND42NADH:ubiquinone reductase 42kD subunit precursor0.050
CG12079CG12079 gene product from transcript CG12079-RA0.045
dj-1betaCG1349 gene product from transcript CG1349-RA0.041
CG8818CG8818 gene product from transcript CG8818-RA0.040
CG10664CG10664 gene product from transcript CG10664-RB0.039
parkparkin0.038
CG3683CG3683 gene product from transcript CG3683-RC0.037
ATPsyn-gammaATP synthase-gamma chain0.034
Act88FActin 88F0.033
levyCG17280 gene product from transcript CG17280-RA0.033
GpdhGlycerol 3 phosphate dehydrogenase0.033
CG3731CG3731 gene product from transcript CG3731-RA0.032
l(3)neo18lethal (3) neo180.029
AconAconitase0.028
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.026
Gpo-1Glycerophosphate oxidase-10.025
CG3192CG3192 gene product from transcript CG3192-RA0.025
CG11876CG11876 gene product from transcript CG11876-RA0.025
flnflightin0.024
TpiTriose phosphate isomerase0.024
l(1)G0334lethal (1) G03340.024
CG12203CG12203 gene product from transcript CG12203-RA0.023
PgkPhosphoglycerate kinase0.023
Mlc2Myosin light chain 20.023
OscpOligomycin sensitivity-conferring protein0.022
rho-7rhomboid-70.020
CG9350CG9350 gene product from transcript CG9350-RA0.020
CG10219CG10219 gene product from transcript CG10219-RA0.019
SdhCSuccinate dehydrogenase C0.018
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.018
NP15.6CG6008 gene product from transcript CG6008-RA0.018
slmoslowmo0.018
l(3)03670lethal (3) 036700.017
CoVaCytochrome c oxidase subunit Va0.016
CG4769CG4769 gene product from transcript CG4769-RA0.015
CG9399CG9399 gene product from transcript CG9399-RC0.014
CG12338CG12338 gene product from transcript CG12338-RA0.013
blwbellwether0.013
CG31937CG31937 gene product from transcript CG31937-RA0.013
CG9140CG9140 gene product from transcript CG9140-RA0.012
CG14290CG14290 gene product from transcript CG14290-RB0.012
uncuncoordinated0.012
l(1)G0230lethal (1) G02300.011
l(1)G0136lethal (1) G01360.011
ND23NADH:ubiquinone reductase 23kD subunit precursor0.011
l(1)G0156lethal (1) G01560.011
fblfumble0.011
Trap1CG3152 gene product from transcript CG3152-RA0.011
ScsalphaSuccinyl coenzyme A synthetase alpha subunit0.011
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Atp5f1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B10.711
Mdh1malate dehydrogenase 1, NAD (soluble)0.537
Idh3Bisocitrate dehydrogenase 3 (NAD+) beta0.365
Pdhbpyruvate dehydrogenase (lipoamide) beta0.316
Fh1fumarate hydratase 10.214
Cycscytochrome c, somatic0.186
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.137
Atp5c1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.097
Sdhdsuccinate dehydrogenase complex, subunit D, integral membrane protein0.083
Uqcrc2ubiquinol cytochrome c reductase core protein 20.057
Brp44lbrain protein 44-like0.049
Dlddihydrolipoamide dehydrogenase0.036
Slc25a5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 50.035
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.035
Cyc1cytochrome c-10.031
Slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.024
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.021
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.021
Suclg1succinate-CoA ligase, alpha subunit0.012
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SDH2Sdh2p0.996
RIP1Rip1p0.993
COR1Cor1p0.977
PET9Pet9p0.971
COX4Cox4p0.970
CYT1Cyt1p0.945
COX6Cox6p0.873
QCR2Qcr2p0.794
QCR7Qcr7p0.779
QCR8Qcr8p0.764
COX1Cox1p0.714
COX13Cox13p0.684
COX2Cox2p0.590
COX5ACox5ap0.533
COX12Cox12p0.451
COBCobp0.434
SDH3Sdh3p0.428
INH1Inh1p0.349
NDE1Nde1p0.340
TIM44Tim44p0.290
QCR9Qcr9p0.264
SDH1Sdh1p0.263
ATP6Atp6p0.196
CYC1Cyc1p0.171
ATP1Atp1p0.166
QCR10Qcr10p0.153
COX3Cox3p0.145
ODC1Odc1p0.124
ACB1Acb1p0.112
MDH1Mdh1p0.105
QCR6Qcr6p0.101
COX8Cox8p0.094
DNM1Dnm1p0.085
YGL010Whypothetical protein0.084
AI1Ai1p0.078
TIM23Tim23p0.074
ATP18Atp18p0.074
YIA6Yia6p0.068
CCC1Ccc1p0.062
YHR140Whypothetical protein0.057
BI4Bi4p0.055
ICS2Ics2p0.052
COX7Cox7p0.052
COX9Cox9p0.052
ATP20Atp20p0.050
PCL9Pcl9p0.044
YOR186Whypothetical protein0.043
YLR264C-Ahypothetical protein0.042
ATP5Atp5p0.040
SRD1Srd1p0.039
CIR2Cir2p0.036
TIM11Tim11p0.035
AIM38Aim38p0.035
ATP2Atp2p0.034
HUG1Hug1p0.034
LEU2Leu2p0.034
YNL146Whypothetical protein0.033
MER1Mer1p0.033
YEL073Chypothetical protein0.032
YCL057C-Ahypothetical protein0.032
YOL038C-Ahypothetical protein0.032
AIM33Aim33p0.031
YLR162Whypothetical protein0.029
CTR3Ctr3p0.029
ARP10Arp10p0.028
URA3Ura3p0.028
COS12Cos12p0.027
MSS51Mss51p0.027
COX14Cox14p0.027
COA3Coa3p0.027
MEP1Mep1p0.027
GLG1Glg1p0.026
OLI1F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP20.026
YLR042Chypothetical protein0.026
YLR040Chypothetical protein0.025
YBR013Chypothetical protein0.024
CUP1-1Cup1-1p0.024
RPS14BRps14bp0.024
MCH2Mch2p0.024
CPD1Cpd1p0.024
TCM62Tcm62p0.023
AGC1Agc1p0.023
GLG2Glg2p0.023
YLR132Chypothetical protein0.023
FAA1Faa1p0.023
YAR068Whypothetical protein0.023
HOR7Hor7p0.022
BI3Bi3p0.021
LSC1Lsc1p0.021
AUA1Aua1p0.020
AAC1Aac1p0.020
YJR120Whypothetical protein0.020
YOL013W-Ahypothetical protein0.020
ACH1Ach1p0.020
BSC1Bsc1p0.020
AQY1Aqy1p0.019
ZPS1Zps1p0.019
FMT1Fmt1p0.019
BNA4Bna4p0.019
HPF1Hpf1p0.019