The network for 'spermatid differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

spermatid differentiation

The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

NameDescriptionProbabilityFunc Analog Organism
HNRNPKheterogeneous nuclear ribonucleoprotein K0.892
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.848
HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)0.847
WASLWiskott-Aldrich syndrome-like0.753
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.649
UBQLN1ubiquilin 10.631
TSKStestis-specific serine kinase substrate0.624
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.595
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.587
QKIquaking homolog, KH domain RNA binding (mouse)0.491
BCL9B-cell CLL/lymphoma 90.488
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.488
SCHIP1schwannomin interacting protein 10.456
TOP1topoisomerase (DNA) I0.433
BCL2L1BCL2-like 10.403
BRCA2breast cancer 2, early onset0.379
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.354
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.348
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.323
PEX14peroxisomal biogenesis factor 140.321
PSEN2presenilin 2 (Alzheimer disease 4)0.307
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.298
EXOC7exocyst complex component 70.297
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.289
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.270
CSNK1A1casein kinase 1, alpha 10.269
BAK1BCL2-antagonist/killer 10.262
DNM1dynamin 10.255
HGShepatocyte growth factor-regulated tyrosine kinase substrate0.254
CLCN3chloride channel 30.247
UQCRC2ubiquinol-cytochrome c reductase core protein II0.247
ELL2elongation factor, RNA polymerase II, 20.245
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.239
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.236
CDHR2cadherin-related family member 20.235
SNX9sorting nexin 90.221
NLRC4NLR family, CARD domain containing 40.220
BCL2B-cell CLL/lymphoma 20.218
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.212
BBS1Bardet-Biedl syndrome 10.210
SMURF1SMAD specific E3 ubiquitin protein ligase 10.205
BCRbreakpoint cluster region0.205
EXOC2exocyst complex component 20.201
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.200
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.199
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.194
FUBP1far upstream element (FUSE) binding protein 10.193
CENPJcentromere protein J0.190
DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.190
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.189
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.187
ATXN1ataxin 10.187
UBR1ubiquitin protein ligase E3 component n-recognin 10.184
EIF3Aeukaryotic translation initiation factor 3, subunit A0.184
DICER1dicer 1, ribonuclease type III0.179
HMGB1high mobility group box 10.175
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.174
PEX5peroxisomal biogenesis factor 50.168
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.168
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.165
CASP4caspase 4, apoptosis-related cysteine peptidase0.164
STRADASTE20-related kinase adaptor alpha0.164
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.164
MATR3matrin 30.164
TNIP2TNFAIP3 interacting protein 20.163
ATP5C1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.162
TCP1t-complex 10.160
MED28mediator complex subunit 280.159
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.157
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.156
ATP13A2ATPase type 13A20.154
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.154
TARDBPTAR DNA binding protein0.151
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.151
BBS2Bardet-Biedl syndrome 20.149
DNM2dynamin 20.149
SHFM1split hand/foot malformation (ectrodactyly) type 10.149
EIF3Feukaryotic translation initiation factor 3, subunit F0.147
LDHBlactate dehydrogenase B0.144
BCAR1breast cancer anti-estrogen resistance 10.142
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.142
ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B10.141
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.137
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.137
CADM4cell adhesion molecule 40.137
KITLGKIT ligand0.133
MAP3K11mitogen-activated protein kinase kinase kinase 110.133
EIF3Eeukaryotic translation initiation factor 3, subunit E0.130
ATP5G3ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)0.128
PSIP1PC4 and SFRS1 interacting protein 10.127
WIPF1WAS/WASL interacting protein family, member 10.126
IQGAP1IQ motif containing GTPase activating protein 10.124
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.124
CYCScytochrome c, somatic0.123
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.121
PDS5BPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.121
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.120
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cc2d2acoiled-coil and C2 domain containing 2A0.739
rhoabras homolog gene family, member Ab0.448
tbpl2TATA box binding protein like 20.425
dag1dystroglycan 10.416
hmgb2ahigh-mobility group box 2a0.328
hmgb3ahigh-mobility group box 3a0.243
lhx1aLIM homeobox 1a0.234
cdc42cell division cycle 420.233
fanclFanconi anemia, complementation group L0.232
hmgb2bhigh-mobility group box 2b0.228
lamc1laminin, gamma 10.211
brca2breast cancer 2, early onset0.207
vdac3voltage-dependent anion channel 30.182
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.174
extl3exostoses (multiple)-like 30.174
cnn2calponin 20.163
cpa5carboxypeptidase A50.157
hmgb1ahigh-mobility group box 1a0.157
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.155
ehd1EH-domain containing 10.152
tcf12transcription factor 120.147
amy2aamylase, alpha 2A; pancreatic0.145
sucla2succinate-CoA ligase, ADP-forming, beta subunit0.140
e2f5E2F transcription factor 50.134
rtcd1RNA terminal phosphate cyclase domain 10.132
flncbfilamin C, gamma b (actin binding protein 280)0.130
msnamoesin a0.126
hmgb1bhigh-mobility group box 1b0.126
ybx1Y box binding protein 10.120
lfnglunatic fringe homolog0.117
ctnnb1catenin (cadherin-associated protein), beta 10.116
mdh1bmalate dehydrogenase 1b, NAD (soluble)0.113
fabp7afatty acid binding protein 7, brain, a0.109
bcambasal cell adhesion molecule (Lutheran blood group)0.109
calm2acalmodulin 2a (phosphorylase kinase, delta)0.106
caspacaspase a0.106
tdrd1tudor domain containing 10.104
trim71tripartite motif-containing 710.104
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.103
flot1bflotillin 1b0.102
ela3lelastase 3 like0.100
btkBruton agammaglobulinemia tyrosine kinase0.100
ranbp1RAN binding protein 10.099
myd88myeloid differentiation primary response gene (88)0.099
palb2partner and localizer of BRCA20.098
lamb2laminin, beta 2 (laminin S)0.096
acsbg2acyl-CoA synthetase bubblegum family member 20.096
cpa4carboxypeptidase A40.093
hnrnph1lheterogeneous nuclear ribonucleoprotein H1, like0.091
nsa2NSA2 ribosome biogenesis homolog (S. cerevisiae)0.089
eif3s2eukaryotic translation initiation factor 3, subunit 2 beta0.089
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.088
ncapgnon-SMC condensin I complex, subunit G0.086
ahcyl2S-adenosylhomocysteine hydrolase-like 20.085
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.085
sgcesarcoglycan, epsilon0.085
odc1ornithine decarboxylase 10.085
cpb1carboxypeptidase B1 (tissue)0.085
piwil2piwi-like 2 (Drosophila)0.083
rab1aRAB1A, member RAS oncogene family0.082
cct8chaperonin containing TCP1, subunit 8 (theta)0.082
cpa1carboxypeptidase A1 (pancreatic)0.082
tpi1btriosephosphate isomerase 1b0.082
tardbpTAR DNA binding protein0.081
lama2laminin, alpha 20.081
sycp3lsynaptonemal complex protein 3 like0.081
ift57intraflagellar transport protein 570.079
kif14kinesin family member 140.076
csf3rcolony stimulating factor 3 receptor (granulocyte)0.076
eng1bengrailed 1b0.076
fb06f03high-mobility group nucleosome binding domain 1-like0.075
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.075
c6ast3six-cysteine containing astacin protease 30.074
syce2synaptonemal complex central element protein 20.074
mkksMcKusick-Kaufman syndrome0.074
fanciFanconi anemia, complementation group I0.072
tpm4tropomyosin 40.072
ssrp1bstructure specific recognition protein 1b0.072
arf2ADP-ribosylation factor 20.071
ctrb1chymotrypsinogen B10.071
pmp22aperipheral myelin protein 22a0.071
mef2camyocyte enhancer factor 2ca0.070
pak2ap21 (CDKN1A)-activated kinase 2a0.068
slc27a2solute carrier family 27 (fatty acid transporter), member 20.068
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
ChcClathrin heavy chain1.000
ctpcut up1.000
djdon juan1.000
betaTub85Dbeta-Tubulin at 85D0.999
Past1Putative Achaete Scute Target 10.999
hydhyperplastic discs0.995
Hsp83Heat shock protein 830.995
yuriyuri gagarin0.994
CG3875CG3875 gene product from transcript CG3875-RA0.993
CG7051CG7051 gene product from transcript CG7051-RA0.993
CG12214CG12214 gene product from transcript CG12214-RB0.990
Cdc42CG12530 gene product from transcript CG12530-RA0.989
kl-3male fertility factor kl30.988
CG10630CG10630 gene product from transcript CG10630-RA0.982
Cyt-c-dCytochrome c distal0.977
aopanterior open0.975
poloCG12306 gene product from transcript CG12306-RA0.964
HtrA2CG8464 gene product from transcript CG8464-RA0.956
KhcKinesin heavy chain0.952
CG5741CG5741 gene product from transcript CG5741-RC0.938
Fmr1CG6203 gene product from transcript CG6203-RC0.927
LaspCG3849 gene product from transcript CG3849-RB0.924
Rab11Rab-protein 110.915
poepurity of essence0.915
aPKCatypical protein kinase C0.903
Taf6TBP-associated factor 60.895
WASpCG1520 gene product from transcript CG1520-RA0.885
Sas-4CG10061 gene product from transcript CG10061-RA0.852
snssticks and stones0.847
Vrp1Verprolin 10.841
Trxr-1Thioredoxin reductase-10.838
Dlc90FDynein light chain 90F0.834
alphaTub84Balpha-Tubulin at 84B0.823
Rac1CG2248 gene product from transcript CG2248-RA0.818
eIF4E-3CG8023 gene product from transcript CG8023-RA0.814
sqhspaghetti squash0.809
numbCG3779 gene product from transcript CG3779-RB0.794
eIF4G2eukaryotic translation initiation factor 4G20.786
pr-set7CG3307 gene product from transcript CG3307-RC0.774
fwdfour wheel drive0.750
mbcmyoblast city0.738
Npc1aNiemann-Pick type C-1a0.720
Cdc37CG12019 gene product from transcript CG12019-RA0.687
CG3124CG3124 gene product from transcript CG3124-RA0.681
LanB1CG7123 gene product from transcript CG7123-RA0.624
CG8443CG8443 gene product from transcript CG8443-RA0.619
spag4sperm-associated antigen 40.616
porinCG6647 gene product from transcript CG6647-RA0.611
chbchromosome bows0.606
Vap-33-1CG5014 gene product from transcript CG5014-RB0.601
pAbppolyA-binding protein0.593
AnceAngiotensin converting enzyme0.590
ana1anastral spindle 10.568
PknProtein kinase related to protein kinase N0.553
CG15657CG15657 gene product from transcript CG15657-RA0.541
Roc1bCG16988 gene product from transcript CG16988-RA0.540
Prosalpha6TProteasome alpha6T subunit0.535
CG5017CG5017 gene product from transcript CG5017-RA0.521
SAKSak kinase0.515
Cog7CG31040 gene product from transcript CG31040-RA0.504
UbcD2Ubiquitin conjugating enzyme 20.498
Hsc70-4Heat shock protein cognate 40.490
Nup154Nucleoporin 1540.475
OsbpOxysterol binding protein0.465
Hsp60CCG7235 gene product from transcript CG7235-RA0.447
Rho1CG8416 gene product from transcript CG8416-RB0.426
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Bcl2B-cell leukemia/lymphoma 20.999
Ptenphosphatase and tensin homolog0.998
Fgfr2fibroblast growth factor receptor 20.986
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.980
Esr1estrogen receptor 1 (alpha)0.978
Gli3GLI-Kruppel family member GLI30.973
Sox2SRY-box containing gene 20.970
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.960
Vegfavascular endothelial growth factor A0.956
Apcadenomatosis polyposis coli0.941
Eya1eyes absent 1 homolog (Drosophila)0.919
Pax2paired box gene 20.919
Chd7chromodomain helicase DNA binding protein 70.912
Grb2growth factor receptor bound protein 20.905
Pitx2paired-like homeodomain transcription factor 20.902
Hnrpdlheterogeneous nuclear ribonucleoprotein D-like0.882
Bmp4bone morphogenetic protein 40.876
Smad4MAD homolog 4 (Drosophila)0.870
Amhr2anti-Mullerian hormone type 2 receptor0.867
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.864
Nf1neurofibromatosis 10.843
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.826
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.816
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.804
LOC100503041PDZ domain-containing protein 7-like0.804
Bbs4Bardet-Biedl syndrome 4 (human)0.797
Apaf1apoptotic peptidase activating factor 10.783
Ctnnb1catenin (cadherin associated protein), beta 10.782
Fgf10fibroblast growth factor 100.775
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.774
Rxraretinoid X receptor alpha0.760
Kdrkinase insert domain protein receptor0.759
Pax6paired box gene 60.751
Shhsonic hedgehog0.747
Zeb1zinc finger E-box binding homeobox 10.747
Itgb1integrin beta 1 (fibronectin receptor beta)0.721
Pax3paired box gene 30.702
Cftrcystic fibrosis transmembrane conductance regulator homolog0.698
Ptpn11protein tyrosine phosphatase, non-receptor type 110.693
Foxc1forkhead box C10.675
TardbpTAR DNA binding protein0.673
Otx2orthodenticle homolog 2 (Drosophila)0.656
Ddx5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.655
Gja1gap junction protein, alpha 10.653
CblCasitas B-lineage lymphoma0.649
Rb1retinoblastoma 10.634
Sox11SRY-box containing gene 110.619
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.618
Kiss1KiSS-1 metastasis-suppressor0.598
Trp53transformation related protein 530.592
Iqcb1IQ calmodulin-binding motif containing 10.549
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.529
Nos3nitric oxide synthase 3, endothelial cell0.516
Pou4f3POU domain, class 4, transcription factor 30.506
Capza1capping protein (actin filament) muscle Z-line, alpha 10.499
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.495
Gbp5guanylate binding protein 50.481
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.480
Matr3matrin 30.470
Akap4A kinase (PRKA) anchor protein 40.468
BaxBCL2-associated X protein0.458
Meox2mesenchyme homeobox 20.453
Fgfr3fibroblast growth factor receptor 30.452
Catsper1cation channel, sperm associated 10.451
Fmr1fragile X mental retardation syndrome 1 homolog0.446
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.432
Smad3MAD homolog 3 (Drosophila)0.428
Bbs2Bardet-Biedl syndrome 2 (human)0.420
Drd2dopamine receptor D20.418
Slc4a7solute carrier family 4, sodium bicarbonate cotransporter, member 70.403
Egfrepidermal growth factor receptor0.403
Ptk2PTK2 protein tyrosine kinase 20.400
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.394
Cdh23cadherin 23 (otocadherin)0.391
Pbx1pre B-cell leukemia transcription factor 10.389
Hnrnprheterogeneous nuclear ribonucleoprotein R0.389
Tcf4transcription factor 40.387
Fzd8frizzled homolog 8 (Drosophila)0.382
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.372
Hnrnpa1heterogeneous nuclear ribonucleoprotein A10.370
Raver2ribonucleoprotein, PTB-binding 20.368
Bmpr1abone morphogenetic protein receptor, type 1A0.367
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.367
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.366
Dmddystrophin, muscular dystrophy0.351
Pgrprogesterone receptor0.349
Gab2growth factor receptor bound protein 2-associated protein 20.348
Isl1ISL1 transcription factor, LIM/homeodomain0.341
Thrbthyroid hormone receptor beta0.337
Pick1protein interacting with C kinase 10.331
BrafBraf transforming gene0.326
Arandrogen receptor0.320
Msx2homeobox, msh-like 20.318
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.317
Atp1a4ATPase, Na+/K+ transporting, alpha 4 polypeptide0.316
Dhx9DEAH (Asp-Glu-Ala-His) box polypeptide 90.308
Ikzf1IKAROS family zinc finger 10.305
H3f3bH3 histone, family 3B0.304
Runx2runt related transcription factor 20.301
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RanRAN, member RAS oncogene family0.028
Tmem126atransmembrane protein 126A0.023
Timm8btranslocase of inner mitochondrial membrane 8 homolog b (yeast)0.020
LOC100359498ribosomal protein L35a-like0.020
Rpl3ribosomal protein L30.018
Ndufa2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 20.017
Mrpl22mitochondrial ribosomal protein L220.016
Rpl10aribosomal protein L10A0.013
Atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.012
Churc1churchill domain containing 10.011
Tomm7translocase of outer mitochondrial membrane 7 homolog (yeast)0.011
Ndufa6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)0.011
Ndufb5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 50.010
Phpt1phosphohistidine phosphatase 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism