The network for 'very long chain fatty acid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

very long chain fatty acid biosynthetic process

The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22.

NameDescriptionProbabilityFunc Analog Organism
TWF2twinfilin, actin-binding protein, homolog 2 (Drosophila)0.349
SC4MOLsterol-C4-methyl oxidase-like0.256
LASS2LAG1 homolog, ceramide synthase 20.065
HMGCR3-hydroxy-3-methylglutaryl-CoA reductase0.062
SQLEsqualene epoxidase0.053
NSDHLNAD(P) dependent steroid dehydrogenase-like0.039
TSPOtranslocator protein (18kDa)0.039
IDI1isopentenyl-diphosphate delta isomerase 10.038
ORMDL2ORM1-like 2 (S. cerevisiae)0.037
FDFT1farnesyl-diphosphate farnesyltransferase 10.032
CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 10.032
DHCR2424-dehydrocholesterol reductase0.030
MFSD5major facilitator superfamily domain containing 50.029
CYB561D2cytochrome b-561 domain containing 20.029
DHCR77-dehydrocholesterol reductase0.028
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.022
CLIC1chloride intracellular channel 10.019
INSIG1insulin induced gene 10.019
ACAT2acetyl-CoA acetyltransferase 20.016
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.016
CREB3cAMP responsive element binding protein 30.012
BCAP31B-cell receptor-associated protein 310.012
FDPSfarnesyl diphosphate synthase0.011
TMBIM1transmembrane BAX inhibitor motif containing 10.011
PSENENpresenilin enhancer 2 homolog (C. elegans)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
hsd17b12ahydroxysteroid (17-beta) dehydrogenase 12a0.855
osbpl7oxysterol binding protein-like 70.729
oclnboccludin b0.381
abcb5ATP-binding cassette, sub-family B (MDR/TAP), member 50.302
elovl7bELOVL family member 7, elongation of long chain fatty acids (yeast) b0.280
fads2fatty acid desaturase 20.253
lpcat4lysophosphatidylcholine acyltransferase 40.208
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.194
slc8a1bsolute carrier family 8 (sodium/calcium exchanger), member 1b0.188
adipor1badiponectin receptor 1b0.161
elovl6lELOVL family member 6, elongation of long chain fatty acids like0.122
sh3gl1aSH3-domain GRB2-like 1a0.111
rab11alRAB11a, member RAS oncogene family, like0.108
adipor2adiponectin receptor 20.108
nos2anitric oxide synthase 2a, inducible0.105
hsd17b12bhydroxysteroid (17-beta) dehydrogenase 12b0.104
atp2b2ATPase, Ca++ transporting, plasma membrane 20.101
pcsk2proprotein convertase subtilisin/kexin type 20.097
gbgt1l4globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 40.094
stk10serine/threonine kinase 100.091
acox1acyl-Coenzyme A oxidase 1, palmitoyl0.090
tjp3tight junction protein 30.088
casrlcalcium-sensing receptor, like0.087
rp2retinitis pigmentosa 2 (X-linked recessive)0.083
gpiaglucose phosphate isomerase a0.077
trpv6transient receptor potential cation channel, subfamily V, member 60.077
lass5LAG1 homolog, ceramide synthase 5 (S. cerevisiae)0.064
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.062
abca12ATP-binding cassette, sub-family A (ABC1), member 120.060
mt2metallothionein 20.058
elovl7aELOVL family member 7, elongation of long chain fatty acids (yeast) a0.057
gperG protein-coupled estrogen receptor 10.053
cd9bCD9 antigen, b0.051
fut9fucosyltransferase 90.051
oclnaoccludin a0.050
slc2a8solute carrier family 2 (facilitated glucose transporter), member 80.050
hprt1hypoxanthine phosphoribosyltransferase 10.049
arpc1bactin related protein 2/3 complex, subunit 1B0.048
abcc1ATP-binding cassette, sub-family C, member 10.048
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.046
fa2hfatty acid 2-hydroxylase0.045
pitpnaphosphatidylinositol transfer protein, alpha0.045
ef1aelongation factor 1-alpha0.044
ildr1aimmunoglobulin-like domain containing receptor 1a0.044
slc25a14solute carrier family 25 (mitochondrial carrier, brain), member 140.043
baiap2l1aBAI1-associated protein 2-like 1a0.040
tm9sf3transmembrane 9 superfamily member 30.039
grhl3grainyhead-like 30.037
slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.037
vtg1vitellogenin 10.035
pcsk1proprotein convertase subtilisin/kexin type 10.034
rrm2bribonucleotide reductase M2 b0.031
fabp7bfatty acid binding protein 7, brain, b0.031
cldngclaudin g0.031
cyp17a1cytochrome P450, family 17, subfamily A, polypeptide 10.031
rhpn2rhophilin, Rho GTPase binding protein 20.030
rspo1R-spondin homolog (Xenopus laevis)0.030
nos2bnitric oxide synthase 2b, inducible0.030
c1galt1bcore 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b0.029
nanos3nanos homolog 30.029
grpel1GrpE-like 1, mitochondrial0.028
tm9sf4transmembrane 9 superfamily protein member 40.028
elovl2elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 20.028
cacnb2bcalcium channel, voltage-dependent, beta 2b0.028
LOC100003330melanocortin-2 receptor accessory protein 2-like0.028
adipor1aadiponectin receptor 1a0.027
cdh17cadherin 17, LI cadherin (liver-intestine)0.026
cldn2claudin 20.026
bmp15bone morphogenetic protein 150.025
mstnamyostatin a0.025
slc16a3solute carrier family 16 (monocarboxylic acid transporters), member 30.024
nr1h3nuclear receptor subfamily 1, group H, member 30.022
rgl3aral guanine nucleotide dissociation stimulator-like 3a0.022
cldnbclaudin b0.022
pnp6purine nucleoside phosphorylase 60.022
pcsk7proprotein convertase subtilisin/kexin type 70.021
ripk4receptor-interacting serine-threonine kinase 40.021
coro1acoronin, actin binding protein, 1A0.021
hprt1lhypoxanthine phosphoribosyltransferase 1, like0.021
foxo3aforkhead box O3A0.021
rln3brelaxin 3b0.021
ftr83finTRIM family, member 830.020
cxadrcoxsackie virus and adenovirus receptor0.020
grn1granulin 10.019
ptgeslprostaglandin E synthase 2-like0.019
slc2a9l1solute carrier family 2 (facilitated glucose transporter), member 9-like 10.019
pitpnbphosphotidylinositol transfer protein, beta0.019
defbl1defensin, beta-like 10.019
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.019
mbnl1muscleblind-like (Drosophila)0.019
atp2b1aATPase, Ca++ transporting, plasma membrane 1a0.019
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG16904CG16904 gene product from transcript CG16904-RA0.999
CG30008CG30008 gene product from transcript CG30008-RA0.997
CG18609CG18609 gene product from transcript CG18609-RA0.991
CG7910CG7910 gene product from transcript CG7910-RA0.913
CG15531CG15531 gene product from transcript CG15531-RB0.845
CG9459CG9459 gene product from transcript CG9459-RA0.769
CG13091CG13091 gene product from transcript CG13091-RA0.769
CG4020CG4020 gene product from transcript CG4020-RA0.553
CG9458CG9458 gene product from transcript CG9458-RA0.525
CG17560CG17560 gene product from transcript CG17560-RA0.464
Fad2CG7923 gene product from transcript CG7923-RA0.436
Cyp4g1Cytochrome P450-4g10.327
CG1443CG1443 gene product from transcript CG1443-RA0.325
CheB93aChemosensory protein B 93a0.124
CG17562CG17562 gene product from transcript CG17562-RA0.101
Sc2CG10849 gene product from transcript CG10849-RA0.093
CG11147CG11147 gene product from transcript CG11147-RA0.076
CG6660CG6660 gene product from transcript CG6660-RA0.075
CG11350CG11350 gene product from transcript CG11350-RB0.066
CG11327CG11327 gene product from transcript CG11327-RA0.066
CG4666CG4666 gene product from transcript CG4666-RA0.062
empepithelial membrane protein0.058
CG17374CG17374 gene product from transcript CG17374-RB0.054
CG8292CG8292 gene product from transcript CG8292-RA0.045
v(2)k05816CG3524 gene product from transcript CG3524-RA0.044
CG12268CG12268 gene product from transcript CG12268-RB0.042
CG34120CG34120 gene product from transcript CG34120-RC0.039
CG10175CG10175 gene product from transcript CG10175-RA0.039
CG18031CG18031 gene product from transcript CG18031-RA0.038
CG6432CG6432 gene product from transcript CG6432-RA0.037
CG1441CG1441 gene product from transcript CG1441-RB0.035
CG10097CG10097 gene product from transcript CG10097-RA0.029
CG7675CG7675 gene product from transcript CG7675-RC0.028
CG9990CG9990 gene product from transcript CG9990-RA0.027
betaTub85Dbeta-Tubulin at 85D0.027
Cpr51ACuticular protein 51A0.025
CG31860CG31860 gene product from transcript CG31860-RB0.024
CG9747CG9747 gene product from transcript CG9747-RA0.024
CG5326CG5326 gene product from transcript CG5326-RA0.019
CG6295CG6295 gene product from transcript CG6295-RA0.019
CG13618CG13618 gene product from transcript CG13618-RA0.018
CG13066CG13066 gene product from transcript CG13066-RB0.018
CG12990CG12990 gene product from transcript CG12990-RA0.018
CG1678CG1678 gene product from transcript CG1678-RA0.018
CG14196CG14196 gene product from transcript CG14196-RA0.018
Gr32aGustatory receptor 32a0.017
CG18404CG18404 gene product from transcript CG18404-RA0.017
CG8736CG8736 gene product from transcript CG8736-RB0.016
ppk25pickpocket 250.016
CG2022CG2022 gene product from transcript CG2022-RB0.016
CG3244CG3244 gene product from transcript CG3244-RA0.016
CG8927CG8927 gene product from transcript CG8927-RA0.016
CG3290CG3290 gene product from transcript CG3290-RA0.016
CG3523CG3523 gene product from transcript CG3523-RA0.015
CG2781CG2781 gene product from transcript CG2781-RA0.015
CG15358CG15358 gene product from transcript CG15358-RA0.015
CG8630CG8630 gene product from transcript CG8630-RA0.015
Lectin-galC1Galactose-specific C-type lectin0.015
CG9430CG9430 gene product from transcript CG9430-RA0.015
CAH2Carbonic anhydrase 20.014
CG6675CG6675 gene product from transcript CG6675-RB0.014
Acp62FAccessory gland peptide 62F0.014
CG7995CG7995 gene product from transcript CG7995-RC0.013
CG11878CG11878 gene product from transcript CG11878-RA0.013
CG12057CG12057 gene product from transcript CG12057-RA0.013
CG5065CG5065 gene product from transcript CG5065-RA0.013
Mst77FMale-specific transcript 77F0.012
CG3097CG3097 gene product from transcript CG3097-RA0.012
CG32154CG32154 gene product from transcript CG32154-RA0.012
ppk23pickpocket 230.012
Rcd2Reduction in Cnn dots 20.012
PebIIIEjaculatory bulb protein III0.012
CG16820CG16820 gene product from transcript CG16820-RA0.012
CG14500CG14500 gene product from transcript CG14500-RA0.012
yellow-hCG1629 gene product from transcript CG1629-RA0.012
CG33173CG33173 gene product from transcript CG33173-RA0.011
eloFelongase F0.011
CG14191CG14191 gene product from transcript CG14191-RA0.011
CG18284CG18284 gene product from transcript CG18284-RB0.011
CG33523CG33523 gene product from transcript CG33523-RD0.011
CG7724CG7724 gene product from transcript CG7724-RA0.011
klhl10CG12423 gene product from transcript CG12423-RB0.011
fzofuzzy onions0.011
CG14949CG14949 gene product from transcript CG14949-RA0.011
Phk-3Pherokine 30.011
CG11353CG11353 gene product from transcript CG11353-RA0.011
TpnC4Troponin C isoform 40.011
Jon65AiiJonah 65Aii0.011
CG5428CG5428 gene product from transcript CG5428-RB0.010
CG5107CG5107 gene product from transcript CG5107-RA0.010
CG4586CG4586 gene product from transcript CG4586-RA0.010
Cpr12ACuticular protein 12A0.010
desat1CG5887 gene product from transcript CG5887-RA0.010
Muc68DMucin 68D0.010
Npc2bNiemann-Pick type C-2b0.010
CG7916CG7916 gene product from transcript CG7916-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mlf2myeloid leukemia factor 20.101
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 10.075
Sqlesqualene epoxidase0.068
Cyp51cytochrome P450, family 510.057
Sptlc2serine palmitoyltransferase, long chain base subunit 20.055
AclyATP citrate lyase0.047
Ebpphenylalkylamine Ca2+ antagonist (emopamil) binding protein0.041
Cyb5bcytochrome b5 type B0.035
0610007P14RikRIKEN cDNA 0610007P14 gene0.034
Aesamino-terminal enhancer of split0.034
CutacutA divalent cation tolerance homolog (E. coli)0.031
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.025
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.023
Rnf5ring finger protein 50.022
Dhcr77-dehydrocholesterol reductase0.019
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.019
Aldoaaldolase A, fructose-bisphosphate0.018
Slc25a11solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 110.018
Sh3bgrl3SH3 domain binding glutamic acid-rich protein-like 30.018
Elovl6ELOVL family member 6, elongation of long chain fatty acids (yeast)0.017
Acsl5acyl-CoA synthetase long-chain family member 50.017
Idi1isopentenyl-diphosphate delta isomerase0.017
Tm7sf2transmembrane 7 superfamily member 20.016
Sc5dsterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)0.016
Asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.015
Cox8acytochrome c oxidase, subunit VIIIa0.015
Narsasparaginyl-tRNA synthetase0.015
Fis1fission 1 (mitochondrial outer membrane) homolog (yeast)0.014
Scd1stearoyl-Coenzyme A desaturase 10.014
Rab1bRAB1B, member RAS oncogene family0.014
Keg1kidney expressed gene 10.012
Sdhcsuccinate dehydrogenase complex, subunit C, integral membrane protein0.012
Pdia3protein disulfide isomerase associated 30.011
Bcap31B-cell receptor-associated protein 310.011
Dhcr2424-dehydrocholesterol reductase0.011
Acat2acetyl-Coenzyme A acetyltransferase 20.011
Slc31a1solute carrier family 31, member 10.011
Lap3leucine aminopeptidase 30.011
Lsslanosterol synthase0.010
Prox1prospero-related homeobox 10.010
Ogdhoxoglutarate dehydrogenase (lipoamide)0.010
Hsd17b7hydroxysteroid (17-beta) dehydrogenase 70.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism