The network for 'negative regulation of multi organism process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of multi organism process

Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.

NameDescriptionProbabilityFunc Analog Organism
SMAD4SMAD family member 40.987
IFI44interferon-induced protein 440.971
SP110SP110 nuclear body protein0.969
JUNjun proto-oncogene0.969
OAS12',5'-oligoadenylate synthetase 1, 40/46kDa0.967
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.951
IFIT3interferon-induced protein with tetratricopeptide repeats 30.941
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.932
TRIM21tripartite motif containing 210.931
ISG15ISG15 ubiquitin-like modifier0.916
IFITM1interferon induced transmembrane protein 1 (9-27)0.907
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.897
IFI44Linterferon-induced protein 44-like0.877
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.863
PMLpromyelocytic leukemia0.839
IFIT1interferon-induced protein with tetratricopeptide repeats 10.813
OASL2'-5'-oligoadenylate synthetase-like0.806
MYD88myeloid differentiation primary response gene (88)0.797
MDM2Mdm2 p53 binding protein homolog (mouse)0.777
IRF7interferon regulatory factor 70.773
HDAC1histone deacetylase 10.768
TGFB1transforming growth factor, beta 10.767
MX2myxovirus (influenza virus) resistance 2 (mouse)0.741
MX1myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)0.702
DTX3Ldeltex 3-like (Drosophila)0.686
STAT1signal transducer and activator of transcription 1, 91kDa0.679
JUNBjun B proto-oncogene0.674
UBE2L6ubiquitin-conjugating enzyme E2L 60.673
PLSCR1phospholipid scramblase 10.646
SP100SP100 nuclear antigen0.614
IRF9interferon regulatory factor 90.586
IFIT2interferon-induced protein with tetratricopeptide repeats 20.569
IFITM3interferon induced transmembrane protein 3 (1-8U)0.551
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.551
IFITM2interferon induced transmembrane protein 2 (1-8D)0.522
DICER1dicer 1, ribonuclease type III0.503
CXCL10chemokine (C-X-C motif) ligand 100.484
SP1Sp1 transcription factor0.455
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.454
PDIA3protein disulfide isomerase family A, member 30.449
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.419
FHL2four and a half LIM domains 20.409
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.404
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.372
CCR5chemokine (C-C motif) receptor 50.350
IFI35interferon-induced protein 350.349
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.349
UBE2Uubiquitin-conjugating enzyme E2U (putative)0.340
PARP12poly (ADP-ribose) polymerase family, member 120.339
CXCL9chemokine (C-X-C motif) ligand 90.323
FKBP1AFK506 binding protein 1A, 12kDa0.322
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.306
FOSFBJ murine osteosarcoma viral oncogene homolog0.306
TMEM173transmembrane protein 1730.302
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.298
MAVSmitochondrial antiviral signaling protein0.272
IFI6interferon, alpha-inducible protein 60.272
DDIT3DNA-damage-inducible transcript 30.266
QKIquaking homolog, KH domain RNA binding (mouse)0.265
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.263
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.262
CYLDcylindromatosis (turban tumor syndrome)0.258
TRAF6TNF receptor-associated factor 60.250
CCL4chemokine (C-C motif) ligand 40.249
NMIN-myc (and STAT) interactor0.246
BTRCbeta-transducin repeat containing0.232
USP18ubiquitin specific peptidase 180.225
CCL5chemokine (C-C motif) ligand 50.222
CCL8chemokine (C-C motif) ligand 80.218
ENGendoglin0.218
TP53tumor protein p530.203
INSRinsulin receptor0.202
GDF5growth differentiation factor 50.202
ICAM1intercellular adhesion molecule 10.195
IFIH1interferon induced with helicase C domain 10.193
OAS32'-5'-oligoadenylate synthetase 3, 100kDa0.191
IFIT5interferon-induced protein with tetratricopeptide repeats 50.191
C19orf66chromosome 19 open reading frame 660.191
SF3B2splicing factor 3b, subunit 2, 145kDa0.188
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.188
IL2RBinterleukin 2 receptor, beta0.188
XAF1XIAP associated factor 10.182
ADARadenosine deaminase, RNA-specific0.181
TRIM41tripartite motif containing 410.180
BMP2bone morphogenetic protein 20.177
GFM1G elongation factor, mitochondrial 10.168
RNF11ring finger protein 110.167
PTBP1polypyrimidine tract binding protein 10.167
MOV10Mov10, Moloney leukemia virus 10, homolog (mouse)0.167
HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)0.161
PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)0.158
RANBP3RAN binding protein 30.157
CCL2chemokine (C-C motif) ligand 20.155
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.151
SKILSKI-like oncogene0.150
CPNE6copine VI (neuronal)0.150
CXCL11chemokine (C-X-C motif) ligand 110.148
SRPK2SRSF protein kinase 20.146
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.144
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.143
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nod1nucleotide-binding oligomerization domain containing 10.017
pcsk1proprotein convertase subtilisin/kexin type 10.017
eomesaeomesodermin homolog a0.017
hoxb1bhomeo box B1b0.016
eif4e1beukaryotic translation initiation factor 4e 1b0.015
ifnphi1interferon phi 10.015
hoxa2bhomeo box A2b0.015
srsf2serine/arginine-rich splicing factor 20.015
tlr3toll-like receptor 30.014
cntn2contactin 20.014
pcsk5aproprotein convertase subtilisin/kexin type 5a0.014
s100sS100 calcium binding protein S0.014
usp10ubiquitin specific peptidase 100.014
wnt10awingless-type MMTV integration site family, member 10a0.014
tlr9toll-like receptor 90.014
fgfr1bfibroblast growth factor receptor 1b0.014
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.014
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.014
alcambactivated leukocyte cell adhesion molecule b0.014
ewsr1aEwing sarcoma breakpoint region 1a0.014
wu:fi42e03wu:fi42e030.014
arl6ip1ADP-ribosylation factor-like 6 interacting protein 10.013
hmx1H6 homeo box 10.013
hoxb2ahomeo box B2a0.013
gro2groucho 20.013
tgfbr2transforming growth factor, beta receptor II0.013
egr2aearly growth response 2a0.013
scamp2secretory carrier membrane protein 20.013
ulk2unc-51-like kinase 2 (C. elegans)0.013
pkzprotein kinase containing Z-DNA binding domains0.013
gphn2gephyrin20.013
mapkapk2amitogen-activated protein kinase-activated protein kinase 2a0.013
mxamyxovirus (influenza) resistance A0.013
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.013
tardbpTAR DNA binding protein0.013
il1binterleukin 1, beta and interleukin 1, beta0.013
synj1synaptojanin 10.013
roraaRAR-related orphan receptor A, paralog a0.013
zgc:77836zgc:778360.013
hoxb3ahomeo box B3a0.013
pl10pl100.013
angpt2angiopoietin 20.013
fzd7bfrizzled homolog 7b0.013
acvr2aactivin receptor IIa0.013
zp2.2zona pellucida glycoprotein 2.20.013
pcsk7proprotein convertase subtilisin/kexin type 70.013
zgc:103471zgc:1034710.013
slc15a1bsolute carrier family 15 (oligopeptide transporter), member 1b0.013
LOC567441interferon-induced protein with tetratricopeptide repeats 5-like0.013
arl8baADP-ribosylation factor-like 8Ba0.013
sdc2syndecan 20.013
psen1presenilin 10.013
dab1adisabled homolog 1a (Drosophila)0.013
LOC565839tumor necrosis factor alpha-induced protein 2-like0.013
fgfr3fibroblast growth factor receptor 30.013
bcl2B-cell leukemia/lymphoma 20.013
lsm14abLSM14 homolog Ab (SCD6, S. cerevisiae)0.013
LOC559914short transient receptor potential channel 2-like0.013
nr5a5nuclear receptor subfamily 5, group A, member 50.013
smek1SMEK homolog 1, suppressor of mek1 (Dictyostelium)0.013
lipclipase, hepatic0.013
rc3rabconnectin 30.013
sec24cSEC24 family, member C (S. cerevisiae)0.013
fstl1bfollistatin-like 1b0.013
luc7lLUC7-like (S. cerevisiae)0.013
LOC100000934hypothetical protein LOC1000009340.013
ripk2receptor-interacting serine-threonine kinase 20.013
LOC100333730l-rhamnose-binding lectin CSL1-like0.013
nos2anitric oxide synthase 2a, inducible0.013
sb:cb247sb:cb2470.013
syap1synapse associated protein 10.013
foxi1forkhead box I10.013
LOC567504interferon-induced protein with tetratricopeptide repeats 5-like0.013
fli1afriend leukemia integration 1a0.013
defbl3defensin, beta-like 30.013
prpf8pre-mRNA processing factor 80.013
evx1even-skipped homeobox 10.013
wu:fi38e01wu:fi38e010.013
ccna1cyclin A10.013
psmb9aproteasome (prosome, macropain) subunit, beta type, 9a0.013
camkvbCaM kinase-like vesicle-associated b0.013
her5hairy-related 50.013
esdesterase D/formylglutathione hydrolase0.013
zar1zygote arrest 10.013
gsx1GS homeobox 10.013
hnrprheterogeneous nuclear ribonucleoprotein R0.013
atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.013
ss18synovial sarcoma translocation, chromosome 18 (H. sapiens)0.013
hoxb1ahomeo box B1a0.013
hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.013
mmp9matrix metalloproteinase 90.013
grk5G protein-coupled receptor kinase 50.013
lzts2aleucine zipper, putative tumor suppressor 2a0.013
mespamesoderm posterior a0.013
zgc:56231zgc:562310.013
LOC559454glypican-5-like0.013
ints6integrator complex subunit 60.013
zp3bzona pellucida glycoprotein 3b0.013
scribscribbled homolog (Drosophila)0.013
ifng1-2interferon, gamma 1-20.013
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
RelRelish0.200
Stat92ESignal-transducer and activator of transcription protein at 92E0.088
mysmyospheroid0.071
grassGram-positive Specific Serine protease0.048
PGRP-LBPeptidoglycan recognition protein LB0.046
Pi3K92ECG4141 gene product from transcript CG4141-RB0.039
CG14614CG14614 gene product from transcript CG14614-RA0.033
PGRP-LFPeptidoglycan recognition protein LF0.033
cazcabeza0.033
bbgbig bang0.032
SPESpatzle-Processing Enzyme0.032
ChcClathrin heavy chain0.030
ph-ppolyhomeotic proximal0.028
Rab7Rab-protein 70.027
coroCG9446 gene product from transcript CG9446-RC0.027
AttAAttacin-A0.027
Patr-1Protein associated with topo II related - 10.025
PGRP-LCPeptidoglycan recognition protein LC0.025
pirkpoor Imd response upon knock-in0.023
GNBP3Gram-negative bacteria binding protein 30.023
CdsACDP diglyceride synthetase0.023
Gadd45CG11086 gene product from transcript CG11086-RA0.022
PGRP-SAPeptidoglycan recognition protein SA0.022
keykenny0.022
upd2unpaired 20.021
PvrPDGF- and VEGF-receptor related0.021
Eaat1Excitatory amino acid transporter 10.020
DabDisabled0.020
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.020
DuoxDual oxidase0.020
McrMacroglobulin complement-related0.020
vimarvisceral mesodermal armadillo-repeats0.019
mtrmmatrimony0.019
RicRas which interacts with Calmodulin0.019
CG42369CG42369 gene product from transcript CG42369-RA0.018
form3formin 30.018
stysprouty0.018
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.018
sinusinuous0.017
foxoforkhead box, sub-group O0.017
Fak56DFocal Adhesion Kinase0.017
pckpickel0.017
Sp7Serine protease 70.017
cindrCIN85 and CD2AP orthologue0.017
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.016
Rab5Rab-protein 50.016
dlpdally-like0.016
LacLachesin0.016
18w18 wheeler0.016
Sema-1bCG6446 gene product from transcript CG6446-RA0.015
kelkelch0.015
M6CG7540 gene product from transcript CG7540-RA0.015
kugkugelei0.015
hydhyperplastic discs0.015
varivaricose0.015
Aef1Adult enhancer factor 10.015
taitaiman0.015
upd3unpaired 30.014
egreiger0.014
CG10650CG10650 gene product from transcript CG10650-RA0.014
Ard1Arrest defective 10.014
StimStromal interaction molecule0.014
PGRP-SDCG7496 gene product from transcript CG7496-RA0.014
crolcrooked legs0.014
Pink1PTEN-induced putative kinase 10.014
CG16718CG16718 gene product from transcript CG16718-RA0.014
stwlstonewall0.013
PGRP-SC1bCG8577 gene product from transcript CG8577-RA0.013
CatCatalase0.013
l(2)37Cclethal (2) 37Cc0.013
miltmilton0.013
CG18594CG18594 gene product from transcript CG18594-RA0.013
Mgat1UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I0.013
psqpipsqueak0.013
rheaCG6831 gene product from transcript CG6831-RA0.013
CG13890CG13890 gene product from transcript CG13890-RA0.012
slowslowdown0.012
TSG101tumor suppressor protein 1010.012
cnccap-n-collar0.012
CG9184CG9184 gene product from transcript CG9184-RB0.012
pshpersephone0.012
Arp87CActin-related protein 87C0.012
fonfondue0.012
unkunkempt0.012
SoxNSoxNeuro0.012
Vha100-1CG1709 gene product from transcript CG1709-RF0.012
Pabp2CG2163 gene product from transcript CG2163-RA0.012
ATP7CG1886 gene product from transcript CG1886-RB0.012
NachCG8178 gene product from transcript CG8178-RA0.012
miramiranda0.012
snostrawberry notch0.012
CG6188CG6188 gene product from transcript CG6188-RA0.012
CG12004CG12004 gene product from transcript CG12004-RC0.012
futschCG34387 gene product from transcript CG34387-RC0.012
p38bCG7393 gene product from transcript CG7393-RA0.011
CG5027CG5027 gene product from transcript CG5027-RA0.011
eaterCG6124 gene product from transcript CG6124-RB0.011
CYLDcylindromatosis0.011
l(2)35Bglethal (2) 35Bg0.011
T-cp1Tcp1-like0.011
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tnftumor necrosis factor0.999
Il10interleukin 100.991
Irf7interferon regulatory factor 70.978
Parp14poly (ADP-ribose) polymerase family, member 140.972
Oasl22'-5' oligoadenylate synthetase-like 20.972
Ddx58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.947
Rtp4receptor transporter protein 40.944
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.939
Ltalymphotoxin A0.884
Stat5asignal transducer and activator of transcription 5A0.883
Oasl12'-5' oligoadenylate synthetase-like 10.870
Ifi44interferon-induced protein 440.861
Unc93b1unc-93 homolog B1 (C. elegans)0.843
Usp18ubiquitin specific peptidase 180.821
Trim30atripartite motif-containing 30A0.813
Irf1interferon regulatory factor 10.801
Slfn4schlafen 40.790
Uba7ubiquitin-like modifier activating enzyme 70.762
Mx2myxovirus (influenza virus) resistance 20.761
Oas32'-5' oligoadenylate synthetase 30.748
Stat3signal transducer and activator of transcription 30.741
Ltflactotransferrin0.734
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.729
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.726
FosFBJ osteosarcoma oncogene0.726
Trim30dtripartite motif-containing 30D0.719
Cd19CD19 antigen0.705
Oas1a2'-5' oligoadenylate synthetase 1A0.701
Ctsgcathepsin G0.695
Tor3atorsin family 3, member A0.695
Dhx58DEXH (Asp-Glu-X-His) box polypeptide 580.687
Irf9interferon regulatory factor 90.683
Oas1b2'-5' oligoadenylate synthetase 1B0.674
Map3k14mitogen-activated protein kinase kinase kinase 140.647
Ccl4chemokine (C-C motif) ligand 40.646
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.619
Rsad2radical S-adenosyl methionine domain containing 20.585
Ifitm3interferon induced transmembrane protein 30.561
FaslFas ligand (TNF superfamily, member 6)0.559
Ccl2chemokine (C-C motif) ligand 20.555
Egr1early growth response 10.543
Efnb2ephrin B20.538
Mx1myxovirus (influenza virus) resistance 10.537
Batfbasic leucine zipper transcription factor, ATF-like0.532
Ifit1interferon-induced protein with tetratricopeptide repeats 10.527
Campcathelicidin antimicrobial peptide0.515
Gbp7guanylate binding protein 70.506
Ngpneutrophilic granule protein0.498
Mapk14mitogen-activated protein kinase 140.496
Per1period homolog 1 (Drosophila)0.493
BC006779cDNA sequence BC0067790.486
Cxcl13chemokine (C-X-C motif) ligand 130.478
Zbp1Z-DNA binding protein 10.469
Ltblymphotoxin B0.463
Gm12185predicted gene 121850.459
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.458
Apoeapolipoprotein E0.436
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.432
Per2period homolog 2 (Drosophila)0.425
Oas22'-5' oligoadenylate synthetase 20.424
Pmlpromyelocytic leukemia0.418
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.412
Ifit3interferon-induced protein with tetratricopeptide repeats 30.399
Stat2signal transducer and activator of transcription 20.399
Raver2ribonucleoprotein, PTB-binding 20.384
Atf3activating transcription factor 30.381
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.379
Cxcr5chemokine (C-X-C motif) receptor 50.366
Socs3suppressor of cytokine signaling 30.351
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.343
Tlr2toll-like receptor 20.321
Samhd1SAM domain and HD domain, 10.304
Nab2Ngfi-A binding protein 20.295
Duox2dual oxidase 20.289
Ifi35interferon-induced protein 350.283
D14Ertd668eDNA segment, Chr 14, ERATO Doi 668, expressed0.282
Il4interleukin 40.278
Isg15ISG15 ubiquitin-like modifier0.278
Trp53transformation related protein 530.276
Mpomyeloperoxidase0.274
Trim21tripartite motif-containing 210.272
Rac1RAS-related C3 botulinum substrate 10.271
Klrk1killer cell lectin-like receptor subfamily K, member 10.265
Foxp3forkhead box P30.263
Ptgs2prostaglandin-endoperoxide synthase 20.254
Reg3gregenerating islet-derived 3 gamma0.254
Socs1suppressor of cytokine signaling 10.250
Cmpk2cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial0.249
Pou2af1POU domain, class 2, associating factor 10.248
Htthuntingtin0.243
Pax8paired box gene 80.241
Cxcl10chemokine (C-X-C motif) ligand 100.233
Robo3roundabout homolog 3 (Drosophila)0.228
Xcl1chemokine (C motif) ligand 10.227
Stat1signal transducer and activator of transcription 10.216
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.213
Ube2l6ubiquitin-conjugating enzyme E2L 60.208
Trim25tripartite motif-containing 250.205
Hckhemopoietic cell kinase0.205
Elaneelastase, neutrophil expressed0.203
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PTK2Ptk2p0.161
BMH1Bmh1p0.110
KDX1Kdx1p0.087
SEF1Sef1p0.073
PPZ1Ppz1p0.070
SGV1Sgv1p0.030
CDC55Cdc55p0.029
HRK1Hrk1p0.025
RLM1Rlm1p0.025
TOR1Tor1p0.024
BRO1Bro1p0.022
MKK1Mkk1p0.020
KIN1Kin1p0.020
VPS4Vps4p0.018
YJL163Chypothetical protein0.018
STE23Ste23p0.017
PPQ1Ppq1p0.017
SDS22Sds22p0.016
STE7Ste7p0.016
ROD1Rod1p0.016
GLG1Glg1p0.015
NUR1Nur1p0.014
ASK10Ask10p0.014
SSK2Ssk2p0.014
ZRG8Zrg8p0.014
HAL5Hal5p0.013
BCK1Bck1p0.012
HHF2Hhf2p0.012
SIS2Sis2p0.012
UBC1Ubc1p0.012
PTP3Ptp3p0.011
TCO89Tco89p0.010
SOK1Sok1p0.010
YPI1Ypi1p0.010