The network for 'negative regulation of posttranscriptional gene silencing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of posttranscriptional gene silencing

Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.

NameDescriptionProbabilityFunc Analog Organism
FOXD3forkhead box D31.000
SP1Sp1 transcription factor0.999
WWP2WW domain containing E3 ubiquitin protein ligase 20.997
PAX3paired box 30.995
SOX10SRY (sex determining region Y)-box 100.992
SOX2SRY (sex determining region Y)-box 20.972
HCFC1host cell factor C1 (VP16-accessory protein)0.875
DAZLdeleted in azoospermia-like0.840
PUM2pumilio homolog 2 (Drosophila)0.768
CSNK2Bcasein kinase 2, beta polypeptide0.749
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.595
EXOSC10exosome component 100.535
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.467
TARDBPTAR DNA binding protein0.329
MOCS3molybdenum cofactor synthesis 30.323
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.294
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.227
UPF1UPF1 regulator of nonsense transcripts homolog (yeast)0.181
MEOX2mesenchyme homeobox 20.138
CUL1cullin 10.126
HRKharakiri, BCL2 interacting protein (contains only BH3 domain)0.124
SOX21SRY (sex determining region Y)-box 210.121
DTX3Ldeltex 3-like (Drosophila)0.108
FTSJD2FtsJ methyltransferase domain containing 20.103
SOX11SRY (sex determining region Y)-box 110.091
POGZpogo transposable element with ZNF domain0.089
SMAD7SMAD family member 70.072
HOXD12homeobox D120.069
SOX1SRY (sex determining region Y)-box 10.065
NOVA2neuro-oncological ventral antigen 20.062
SH3RF3SH3 domain containing ring finger 30.059
ESR2estrogen receptor 2 (ER beta)0.057
HMGA1high mobility group AT-hook 10.057
POU3F2POU class 3 homeobox 20.056
UPF2UPF2 regulator of nonsense transcripts homolog (yeast)0.054
MOV10Mov10, Moloney leukemia virus 10, homolog (mouse)0.050
OLIG2oligodendrocyte lineage transcription factor 20.048
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.048
CHN2chimerin (chimaerin) 20.047
OTPorthopedia homeobox0.044
TOP1topoisomerase (DNA) I0.043
SH3RF1SH3 domain containing ring finger 10.042
ADARB1adenosine deaminase, RNA-specific, B10.041
FOXE1forkhead box E1 (thyroid transcription factor 2)0.040
NR0B1nuclear receptor subfamily 0, group B, member 10.040
PDLIM7PDZ and LIM domain 7 (enigma)0.039
MEX3Bmex-3 homolog B (C. elegans)0.038
LHX1LIM homeobox 10.038
POU3F3POU class 3 homeobox 30.037
CHD8chromodomain helicase DNA binding protein 80.037
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.037
SIN3ASIN3 homolog A, transcription regulator (yeast)0.036
NKX2-1NK2 homeobox 10.035
ATF7IPactivating transcription factor 7 interacting protein0.035
FHOD1formin homology 2 domain containing 10.034
ETS2v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)0.034
XIAPX-linked inhibitor of apoptosis0.034
XPO7exportin 70.033
POU4F1POU class 4 homeobox 10.032
NEUROG3neurogenin 30.031
CSNK2A2casein kinase 2, alpha prime polypeptide0.030
DZIP1DAZ interacting protein 10.029
GRIP1glutamate receptor interacting protein 10.028
NR5A1nuclear receptor subfamily 5, group A, member 10.027
ASCL1achaete-scute complex homolog 1 (Drosophila)0.025
DICER1dicer 1, ribonuclease type III0.025
ESR1estrogen receptor 10.025
POU3F4POU class 3 homeobox 40.023
OCRLoculocerebrorenal syndrome of Lowe0.023
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.023
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.022
RAXretina and anterior neural fold homeobox0.022
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.022
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.021
TLX2T-cell leukemia homeobox 20.021
NPAS1neuronal PAS domain protein 10.021
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.020
POU3F1POU class 3 homeobox 10.020
KPNA6karyopherin alpha 6 (importin alpha 7)0.020
C10orf46chromosome 10 open reading frame 460.019
NKX6-1NK6 homeobox 10.019
DIDO1death inducer-obliterator 10.019
GATA5GATA binding protein 50.019
PURBpurine-rich element binding protein B0.019
RNF114ring finger protein 1140.018
TP73tumor protein p730.018
PRMT2protein arginine methyltransferase 20.018
CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 10.018
GALR1galanin receptor 10.018
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.018
ZBTB17zinc finger and BTB domain containing 170.017
MTA2metastasis associated 1 family, member 20.017
ARFIP2ADP-ribosylation factor interacting protein 20.017
TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta)0.017
POU4F2POU class 4 homeobox 20.017
ZNF143zinc finger protein 1430.017
NHLH2nescient helix loop helix 20.016
FLNBfilamin B, beta0.016
LILRA4leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 40.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Sall4sal-like 4 (Drosophila)0.999
NanogNanog homeobox0.993
Tcfcp2l1transcription factor CP2-like 10.980
Sall1sal-like 1 (Drosophila)0.666
Nr0b1nuclear receptor subfamily 0, group B, member 10.611
Esrrbestrogen related receptor, beta0.356
Sall3sal-like 3 (Drosophila)0.140
Sh3gl2SH3-domain GRB2-like 20.110
Sox2SRY-box containing gene 20.109
RybpRING1 and YY1 binding protein0.077
Rnf2ring finger protein 20.056
Mta1metastasis associated 10.052
Arid3bAT rich interactive domain 3B (BRIGHT-like)0.050
Mta3metastasis associated 30.048
Gatad2bGATA zinc finger domain containing 2B0.047
Zfp42zinc finger protein 420.045
Zic2zinc finger protein of the cerebellum 20.035
Rcor2REST corepressor 20.035
Rfx2regulatory factor X, 2 (influences HLA class II expression)0.034
Chd4chromodomain helicase DNA binding protein 40.033
Grin2cglutamate receptor, ionotropic, NMDA2C (epsilon 3)0.030
Fbxo15F-box protein 150.027
Cubncubilin (intrinsic factor-cobalamin receptor)0.024
Ep400E1A binding protein p4000.023
Dnmt3lDNA (cytosine-5-)-methyltransferase 3-like0.023
Dmc1DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)0.023
Ybx2Y box protein 20.022
Zfp219zinc finger protein 2190.022
Actn3actinin alpha 30.022
Dmrt1doublesex and mab-3 related transcription factor 10.021
Ddx4DEAD (Asp-Glu-Ala-Asp) box polypeptide 40.021
Naa11N(alpha)-acetyltransferase 11, NatA catalytic subunit0.020
Dync1i1dynein cytoplasmic 1 intermediate chain 10.019
Myst2MYST histone acetyltransferase 20.018
Dpep3dipeptidase 30.018
Hist3h2bb-pshistone cluster 3, H2bb, pseudogene0.018
Sox15SRY-box containing gene 150.017
Cabin1calcineurin binding protein 10.017
Tsxtestis specific X-linked gene0.016
Hcfc1host cell factor C10.014
Cacnb2calcium channel, voltage-dependent, beta 2 subunit0.014
Nfrkbnuclear factor related to kappa B binding protein0.014
Stat2signal transducer and activator of transcription 20.014
Klf5Kruppel-like factor 50.014
Mesp1mesoderm posterior 10.013
Trap1atumor rejection antigen P1A0.013
Baz2abromodomain adjacent to zinc finger domain, 2A0.012
Lig3ligase III, DNA, ATP-dependent0.012
Myl10myosin, light chain 10, regulatory0.012
L3mbtl2l(3)mbt-like 2 (Drosophila)0.012
Otx2orthodenticle homolog 2 (Drosophila)0.012
Trraptransformation/transcription domain-associated protein0.011
Dppa5adevelopmental pluripotency associated 5A0.011
Fgf8fibroblast growth factor 80.011
Stat1signal transducer and activator of transcription 10.011
Ubn2ubinuclein 20.011
Pmlpromyelocytic leukemia0.010
Dusp9dual specificity phosphatase 90.010
Phlda2pleckstrin homology-like domain, family A, member 20.010
Mta2metastasis-associated gene family, member 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism