The network for 'regulation of endothelial cell apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of endothelial cell apoptotic process

Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.

NameDescriptionProbabilityFunc Analog Organism
CASP8caspase 8, apoptosis-related cysteine peptidase0.947
SQSTM1sequestosome 10.930
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.912
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.906
VEGFAvascular endothelial growth factor A0.819
TEKTEK tyrosine kinase, endothelial0.800
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.755
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.729
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.727
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.684
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.677
FGAfibrinogen alpha chain0.673
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.671
CFLARCASP8 and FADD-like apoptosis regulator0.663
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.649
TAL1T-cell acute lymphocytic leukemia 10.626
FASFas (TNF receptor superfamily, member 6)0.615
FGBfibrinogen beta chain0.611
SHC1SHC (Src homology 2 domain containing) transforming protein 10.600
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.571
TRAF5TNF receptor-associated factor 50.534
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.510
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.490
CASP10caspase 10, apoptosis-related cysteine peptidase0.438
KEAP1kelch-like ECH-associated protein 10.435
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.428
AXLAXL receptor tyrosine kinase0.425
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.409
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.360
CDH5cadherin 5, type 2 (vascular endothelium)0.351
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.305
LATlinker for activation of T cells0.303
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.295
SH3KBP1SH3-domain kinase binding protein 10.292
FGGfibrinogen gamma chain0.284
TRAF6TNF receptor-associated factor 60.264
TRAF1TNF receptor-associated factor 10.263
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.259
SOS1son of sevenless homolog 1 (Drosophila)0.240
BCAR1breast cancer anti-estrogen resistance 10.228
TNFtumor necrosis factor0.219
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.206
PLAUplasminogen activator, urokinase0.180
FYNFYN oncogene related to SRC, FGR, YES0.171
EGFRepidermal growth factor receptor0.168
PTPRBprotein tyrosine phosphatase, receptor type, B0.155
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.143
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.143
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.138
TNFAIP3tumor necrosis factor, alpha-induced protein 30.135
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.134
MAP3K8mitogen-activated protein kinase kinase kinase 80.127
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.126
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.126
FADDFas (TNFRSF6)-associated via death domain0.125
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.121
TRAF3TNF receptor-associated factor 30.116
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.115
NFE2L2nuclear factor (erythroid-derived 2)-like 20.112
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.110
PLATplasminogen activator, tissue0.109
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.100
BIRC3baculoviral IAP repeat containing 30.099
PRKCZprotein kinase C, zeta0.096
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.092
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.086
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.086
TRAF2TNF receptor-associated factor 20.080
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.078
ANGPT2angiopoietin 20.077
CRPC-reactive protein, pentraxin-related0.071
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.069
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.068
SYKspleen tyrosine kinase0.067
TRADDTNFRSF1A-associated via death domain0.067
S100BS100 calcium binding protein B0.065
ZMYND11zinc finger, MYND-type containing 110.065
MAP3K14mitogen-activated protein kinase kinase kinase 140.064
FGFR1fibroblast growth factor receptor 10.062
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.058
LAPTM5lysosomal protein transmembrane 50.057
TGFB1transforming growth factor, beta 10.056
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.055
CDCP1CUB domain containing protein 10.055
ANGPT1angiopoietin 10.054
SH3RF1SH3 domain containing ring finger 10.054
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.052
PECAM1platelet/endothelial cell adhesion molecule0.051
LRP1low density lipoprotein receptor-related protein 10.049
TNFAIP2tumor necrosis factor, alpha-induced protein 20.048
SPRR2Asmall proline-rich protein 2A0.048
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.046
TIE1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.045
KITLGKIT ligand0.045
TNIP1TNFAIP3 interacting protein 10.043
BCL3B-cell CLL/lymphoma 30.042
TNFRSF9tumor necrosis factor receptor superfamily, member 90.041
MAP2K5mitogen-activated protein kinase kinase 50.040
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fggfibrinogen gamma chain0.737
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.452
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.401
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.392
Fgafibrinogen alpha chain0.367
Cdh5cadherin 50.324
Col4a2collagen, type IV, alpha 20.241
Ptk2PTK2 protein tyrosine kinase 20.213
Vhlvon Hippel-Lindau tumor suppressor0.213
Itgb1integrin beta 1 (fibronectin receptor beta)0.204
Apoeapolipoprotein E0.156
Ric8resistance to inhibitors of cholinesterase 8 homolog (C. elegans)0.150
FasFas (TNF receptor superfamily member 6)0.145
Vegfavascular endothelial growth factor A0.139
Traf2TNF receptor-associated factor 20.134
Cd44CD44 antigen0.128
Ifngr1interferon gamma receptor 10.124
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.112
Sox18SRY-box containing gene 180.108
Pecam1platelet/endothelial cell adhesion molecule 10.104
Notch2Notch gene homolog 2 (Drosophila)0.103
Cd151CD151 antigen0.102
Ifnginterferon gamma0.094
Map3k8mitogen-activated protein kinase kinase kinase 80.094
Ambpalpha 1 microglobulin/bikunin0.092
Col3a1collagen, type III, alpha 10.085
Mmp9matrix metallopeptidase 90.085
Bcl2B-cell leukemia/lymphoma 20.083
Arhgef2rho/rac guanine nucleotide exchange factor (GEF) 20.078
Ccl2chemokine (C-C motif) ligand 20.072
Lama2laminin, alpha 20.071
Lyz2lysozyme 20.071
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.070
Flt4FMS-like tyrosine kinase 40.069
Tekendothelial-specific receptor tyrosine kinase0.067
Mt2metallothionein 20.061
Vegfcvascular endothelial growth factor C0.060
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.059
Nf1neurofibromatosis 10.058
Grb2growth factor receptor bound protein 20.056
Mt1metallothionein 10.055
Shhsonic hedgehog0.053
Kdrkinase insert domain protein receptor0.047
Esamendothelial cell-specific adhesion molecule0.046
Gdf10growth differentiation factor 100.045
Hmox1heme oxygenase (decycling) 10.045
Col6a3collagen, type VI, alpha 30.044
Icam2intercellular adhesion molecule 20.038
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.038
Sdprserum deprivation response0.038
Flt1FMS-like tyrosine kinase 10.037
Timp3tissue inhibitor of metalloproteinase 30.037
Apcadenomatosis polyposis coli0.037
Ptprbprotein tyrosine phosphatase, receptor type, B0.037
Birc3baculoviral IAP repeat-containing 30.037
Traf6TNF receptor-associated factor 60.037
Clec14aC-type lectin domain family 14, member a0.035
Fgfr1fibroblast growth factor receptor 10.034
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.033
Akap12A kinase (PRKA) anchor protein (gravin) 120.033
Tnfaip3tumor necrosis factor, alpha-induced protein 30.032
Tlr4toll-like receptor 40.031
Pzppregnancy zone protein0.030
Cd5lCD5 antigen-like0.030
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.030
Ppargperoxisome proliferator activated receptor gamma0.029
Nid1nidogen 10.029
Vav2vav 2 oncogene0.029
Arap3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 30.029
VwfVon Willebrand factor homolog0.028
BtkBruton agammaglobulinemia tyrosine kinase0.027
Mfap2microfibrillar-associated protein 20.027
Itga5integrin alpha 5 (fibronectin receptor alpha)0.027
Prkcdprotein kinase C, delta0.027
Vdrvitamin D receptor0.026
Stab1stabilin 10.026
Hsd11b2hydroxysteroid 11-beta dehydrogenase 20.026
Mdm2transformed mouse 3T3 cell double minute 20.026
Smad3MAD homolog 3 (Drosophila)0.025
Angptl4angiopoietin-like 40.025
ItkIL2-inducible T-cell kinase0.024
Tnip1TNFAIP3 interacting protein 10.024
Mcammelanoma cell adhesion molecule0.024
Fgbfibrinogen beta chain0.024
Tmem204transmembrane protein 2040.024
Gcgroup specific component0.023
Fcgr2bFc receptor, IgG, low affinity IIb0.023
Thbs2thrombospondin 20.023
Rasip1Ras interacting protein 10.023
Cd40CD40 antigen0.023
NynrinNYN domain and retroviral integrase containing0.023
C3complement component 30.023
Maffv-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)0.023
Tgfb1transforming growth factor, beta 10.022
Mysm1myb-like, SWIRM and MPN domains 10.022
Rhojras homolog gene family, member J0.022
Angptl3angiopoietin-like 30.022
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Kng1kininogen 10.170
Fgafibrinogen alpha chain0.169
C4bpacomplement component 4 binding protein, alpha0.167
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.105
Ccl2chemokine (C-C motif) ligand 20.093
Fggfibrinogen gamma chain0.081
Apobapolipoprotein B0.067
Leprleptin receptor0.065
Ambpalpha-1-microglobulin/bikunin precursor0.055
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.050
Apoa1apolipoprotein A-I0.047
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.043
Pdk4pyruvate dehydrogenase kinase, isozyme 40.041
Fabp1fatty acid binding protein 1, liver0.038
Anxa4annexin A40.034
MdficMyoD family inhibitor domain containing0.031
Cr1lcomplement component (3b/4b) receptor 1-like0.030
Apohapolipoprotein H (beta-2-glycoprotein I)0.029
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.028
Adora2aadenosine A2a receptor0.028
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.027
Orm1orosomucoid 10.027
Ghrgrowth hormone receptor0.026
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.026
CebpdCCAAT/enhancer binding protein (C/EBP), delta0.025
Tnftumor necrosis factor (TNF superfamily, member 2)0.025
Fetubfetuin B0.024
Il1binterleukin 1 beta0.024
Irs3insulin receptor substrate 30.024
Lamp2lysosomal-associated membrane protein 20.023
Adfpadipose differentiation related protein0.023
Frzbfrizzled-related protein0.023
Ccl3chemokine (C-C motif) ligand 30.022
Cxcl10chemokine (C-X-C motif) ligand 100.022
Tgm1transglutaminase 1, K polypeptide0.022
C4bpbcomplement component 4 binding protein, beta0.022
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.021
LOC500300similar to hypothetical protein MGC68350.020
Angpt2angiopoietin 20.020
Pzppregnancy-zone protein0.020
Cd36CD36 molecule (thrombospondin receptor)0.020
FasFas (TNF receptor superfamily, member 6)0.020
Ier3immediate early response 30.018
Il4rainterleukin 4 receptor, alpha0.018
Anpepalanyl (membrane) aminopeptidase0.017
Il1r2interleukin 1 receptor, type II0.017
Atf3activating transcription factor 30.017
Icam1intercellular adhesion molecule 10.017
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.017
Tgfbr2transforming growth factor, beta receptor II0.017
Lgals9lectin, galactoside-binding, soluble, 90.017
Rai14retinoic acid induced 140.017
Hdac10histone deacetylase 100.016
Itih4inter alpha-trypsin inhibitor, heavy chain 40.016
Defadefensin, alpha 5, Paneth cell-specific0.016
Aldobaldolase B, fructose-bisphosphate0.016
Gja4gap junction protein, alpha 40.016
Pla1aphospholipase A1 member A0.016
Tnfrsf12atumor necrosis factor receptor superfamily, member 12a0.016
RGD1311307similar to 1300014I06Rik protein0.015
PawrPRKC, apoptosis, WT1, regulator0.015
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.015
Sulf1sulfatase 10.015
Slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.015
Ptgfrprostaglandin F receptor0.015
Plaurplasminogen activator, urokinase receptor0.014
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.014
Btg1B-cell translocation gene 1, anti-proliferative0.014
Kng2kininogen 20.014
Vnn1vanin 10.014
Il13ra1interleukin 13 receptor, alpha 10.014
Bdkrb2bradykinin receptor B20.014
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.014
Cyr61cysteine-rich, angiogenic inducer, 610.014
Il15interleukin 150.013
LOC684996similar to chromosome 7 open reading frame 110.013
F2coagulation factor II (thrombin)0.013
Hdac7histone deacetylase 70.013
Tor1aip2torsin A interacting protein 20.013
LOC293989cytochrome P450-like0.013
Hspa12bheat shock protein 12B0.013
PVRpoliovirus receptor0.013
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.013
Cercamcerebral endothelial cell adhesion molecule0.013
Ier5limmediate early response 5-like0.012
S100a8S100 calcium binding protein A80.012
Sepp1selenoprotein P, plasma, 10.012
Rararetinoic acid receptor, alpha0.012
Baatbile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)0.012
Igf2insulin-like growth factor 20.012
Sox17SRY (sex determining region Y)-box 170.012
Lama5laminin, alpha 50.012
Runx1runt-related transcription factor 10.012
Apoa2apolipoprotein A-II0.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism