The network for 'production of sirna involved in rna interference' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

production of sirna involved in rna interference

Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.

NameDescriptionProbabilityFunc Analog Organism
EIF2C1eukaryotic translation initiation factor 2C, 10.998
DICER1dicer 1, ribonuclease type III0.998
EIF2C2eukaryotic translation initiation factor 2C, 20.994
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.991
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.975
EIF2C3eukaryotic translation initiation factor 2C, 30.723
TNRC6Atrinucleotide repeat containing 6A0.406
PABPC1poly(A) binding protein, cytoplasmic 10.252
TARBP2TAR (HIV-1) RNA binding protein 20.152
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.136
GEMIN4gem (nuclear organelle) associated protein 40.129
TNRC6Ctrinucleotide repeat containing 6C0.082
THOC4THO complex 40.061
EIF2C4eukaryotic translation initiation factor 2C, 40.061
NCBP1nuclear cap binding protein subunit 1, 80kDa0.059
TNRC6Btrinucleotide repeat containing 6B0.045
CYLDcylindromatosis (turban tumor syndrome)0.029
C17orf85chromosome 17 open reading frame 850.026
EIF4G1eukaryotic translation initiation factor 4 gamma, 10.026
ZFP28zinc finger protein 28 homolog (mouse)0.026
SAMD9Lsterile alpha motif domain containing 9-like0.025
IFIT5interferon-induced protein with tetratricopeptide repeats 50.022
TRIM25tripartite motif containing 250.020
ISG15ISG15 ubiquitin-like modifier0.019
NKRFNFKB repressing factor0.019
EPSTI1epithelial stromal interaction 1 (breast)0.017
ZC3HAV1zinc finger CCCH-type, antiviral 10.016
PARNpoly(A)-specific ribonuclease (deadenylation nuclease)0.016
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.016
NCBP2nuclear cap binding protein subunit 2, 20kDa0.013
SNX5sorting nexin 50.013
PARP9poly (ADP-ribose) polymerase family, member 90.012
DTX3Ldeltex 3-like (Drosophila)0.012
HNRNPA1heterogeneous nuclear ribonucleoprotein A10.011
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.011
SAMD9sterile alpha motif domain containing 90.011
RBM8ARNA binding motif protein 8A0.011
CAND1cullin-associated and neddylation-dissociated 10.011
ZNF746zinc finger protein 7460.010
HERC5hect domain and RLD 50.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
dcr-1Protein DCR-10.111
F31C3.3Protein F31C3.30.101
spk-1Protein SPK-10.077
mcm-2Protein MCM-20.065
mix-1Protein MIX-10.065
glh-4Protein GLH-40.048
rfp-1Protein RFP-10.040
rod-1Protein ROD-10.039
C28A5.2Protein C28A5.20.029
mog-1Protein MOG-10.029
wago-2Protein WAGO-20.028
fli-1Protein FLI-10.026
B0001.2Protein B0001.20.025
ZK1098.1Protein ZK1098.10.024
unc-40Protein UNC-400.022
set-16Protein SET-160.021
rrf-1Protein RRF-10.021
rbr-2Protein RBR-20.021
kup-1Protein KUP-10.020
lin-66Protein LIN-660.020
sax-3Protein SAX-30.020
CELE_Y48B6A.1Protein Y48B6A.10.019
sacy-1Protein SACY-10.018
prg-2Protein PRG-20.017
ztf-4Protein ZTF-40.017
polq-1Protein POLQ-10.017
hpo-10Protein HPO-100.017
K02B12.5Protein K02B12.50.016
C01H6.9Protein C01H6.90.016
fzo-1Protein FZO-10.016
klp-10Protein KLP-100.016
glh-1Protein GLH-10.015
C14C10.5Protein C14C10.50.015
lea-1Protein LEA-10.014
ulp-1Protein ULP-10.014
hmp-1Protein HMP-10.014
ehbp-1Protein EHBP-10.014
hsp-4Protein HSP-40.013
ocrl-1Protein OCRL-10.013
flt-1Protein FLT-10.013
mcm-5Protein MCM-50.013
mbtr-1Protein MBTR-10.013
drh-3Protein DRH-30.013
CELE_ZK682.2Protein ZK682.20.012
F21F3.4Protein F21F3.40.012
T01D3.5Protein T01D3.50.012
D2045.2Protein D2045.20.012
swsn-4Protein SWSN-40.012
rad-50Protein RAD-500.012
F35G12.4Protein F35G12.40.011
ZC434.7Protein ZC434.70.011
drh-1Protein DRH-10.011
F36A2.13Protein F36A2.130.010
CELE_C55A6.10Protein C55A6.100.010
smg-2Protein SMG-20.010
K06A5.1Protein K06A5.10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
piwiCG6122 gene product from transcript CG6122-RA0.214
spn-Espindle E0.212
pashapartner of drosha0.172
droshaCG8730 gene product from transcript CG8730-RA0.111
Su(var)2-10Suppressor of variegation 2-100.103
MAN1CG3167 gene product from transcript CG3167-RA0.070
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.049
Ge-1CG6181 gene product from transcript CG6181-RA0.045
stilstand still0.024
Sra-1specifically Rac1-associated protein 10.023
htshu li tai shao0.021
Cap-GCG34438 gene product from transcript CG34438-RF0.021
CG8443CG8443 gene product from transcript CG8443-RA0.021
Rpd3CG7471 gene product from transcript CG7471-RA0.020
Vps16AVacuolar protein sorting 16A0.019
CG4973CG4973 gene product from transcript CG4973-RA0.019
E(var)3-9Enhancer of variegation 3-90.017
msl-3male-specific lethal 30.017
PGRP-LCPeptidoglycan recognition protein LC0.016
orboo18 RNA-binding protein0.015
CTCFCG8591 gene product from transcript CG8591-RA0.014
l(2)35Bglethal (2) 35Bg0.014
stetstem cell tumor0.013
Sam-SS-adenosylmethionine Synthetase0.012
Top2Topoisomerase 20.012
CG4771CG4771 gene product from transcript CG4771-RA0.012
tho2CG31671 gene product from transcript CG31671-RA0.012
bambag of marbles0.012
zpgzero population growth0.012
BicDBicaudal D0.011
Su(var)3-3Suppressor of variegation 3-30.011
hydhyperplastic discs0.011
r2d2CG7138 gene product from transcript CG7138-RB0.011
CG10107CG10107 gene product from transcript CG10107-RA0.011
fs(1)Ybfemale sterile (1) Yb0.010
CHORDCG6198 gene product from transcript CG6198-RA0.010
Tango6Transport and Golgi organization 60.010
nudECG8104 gene product from transcript CG8104-RB0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Brd4bromodomain containing 40.025
Ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.025
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.022
Trim32tripartite motif-containing 320.018
Apcadenomatosis polyposis coli0.011
Cfdp1craniofacial development protein 10.011
Trim25tripartite motif-containing 250.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism