The network for 'positive regulation of tyrosine phosphorylation of stat5 protein' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of tyrosine phosphorylation of stat5 protein

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat5 protein.

NameDescriptionProbabilityFunc Analog Organism
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1.000
EGFRepidermal growth factor receptor1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.997
SHC1SHC (Src homology 2 domain containing) transforming protein 10.987
GRB2growth factor receptor-bound protein 20.985
LATlinker for activation of T cells0.973
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.961
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.952
GH1growth hormone 10.946
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.819
ITGB1BP3integrin beta 1 binding protein 30.779
SOS1son of sevenless homolog 1 (Drosophila)0.769
IGF1Rinsulin-like growth factor 1 receptor0.764
CSH1chorionic somatomammotropin hormone 1 (placental lactogen)0.762
IL23Ainterleukin 23, alpha subunit p190.758
INSRinsulin receptor0.754
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.677
SYKspleen tyrosine kinase0.673
VEGFAvascular endothelial growth factor A0.669
GAB1GRB2-associated binding protein 10.653
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.634
CSHL1chorionic somatomammotropin hormone-like 10.472
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.436
IL4Rinterleukin 4 receptor0.415
PLCG1phospholipase C, gamma 10.398
CSH2chorionic somatomammotropin hormone 20.352
PTPN1protein tyrosine phosphatase, non-receptor type 10.336
JAK2Janus kinase 20.328
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.324
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.321
GHRgrowth hormone receptor0.286
GAB2GRB2-associated binding protein 20.283
PTPRBprotein tyrosine phosphatase, receptor type, B0.233
SOCS3suppressor of cytokine signaling 30.230
FYNFYN oncogene related to SRC, FGR, YES0.216
CDH5cadherin 5, type 2 (vascular endothelium)0.208
IRS1insulin receptor substrate 10.192
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.183
NRP1neuropilin 10.137
GH2growth hormone 20.136
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.136
FGFR1fibroblast growth factor receptor 10.134
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.133
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.132
NTRK1neurotrophic tyrosine kinase, receptor, type 10.129
EPORerythropoietin receptor0.119
PTPN11protein tyrosine phosphatase, non-receptor type 110.114
CMIPc-Maf-inducing protein0.106
METmet proto-oncogene (hepatocyte growth factor receptor)0.100
PGFplacental growth factor0.093
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.081
KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.077
JAK1Janus kinase 10.077
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.074
CSF2RAcolony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)0.071
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.067
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.065
VAV1vav 1 guanine nucleotide exchange factor0.054
SOCS1suppressor of cytokine signaling 10.049
PTPN6protein tyrosine phosphatase, non-receptor type 60.048
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.043
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.043
PTPRJprotein tyrosine phosphatase, receptor type, J0.041
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.038
SH3BP2SH3-domain binding protein 20.038
IGF2Rinsulin-like growth factor 2 receptor0.036
IL12Ainterleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)0.035
SLASrc-like-adaptor0.032
CNTFciliary neurotrophic factor0.032
PDGFAplatelet-derived growth factor alpha polypeptide0.031
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.029
KITLGKIT ligand0.028
SH3KBP1SH3-domain kinase binding protein 10.026
FAF1Fas (TNFRSF6) associated factor 10.026
SHC2SHC (Src homology 2 domain containing) transforming protein 20.025
UBASH3Bubiquitin associated and SH3 domain containing B0.025
PECAM1platelet/endothelial cell adhesion molecule0.024
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide0.023
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.021
CD28CD28 molecule0.020
LIFleukemia inhibitory factor (cholinergic differentiation factor)0.020
STAT5Asignal transducer and activator of transcription 5A0.020
DDR2discoidin domain receptor tyrosine kinase 20.019
BCAR1breast cancer anti-estrogen resistance 10.017
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.016
LDLRlow density lipoprotein receptor0.016
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.016
CD247CD247 molecule0.015
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.014
PDGFCplatelet derived growth factor C0.014
ITGB1BP1integrin beta 1 binding protein 10.013
ABL2v-abl Abelson murine leukemia viral oncogene homolog 20.013
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.012
IL6Rinterleukin 6 receptor0.012
IL2RGinterleukin 2 receptor, gamma0.012
JAK3Janus kinase 30.012
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.011
HCKhemopoietic cell kinase0.011
TEKTEK tyrosine kinase, endothelial0.011
SOS2son of sevenless homolog 2 (Drosophila)0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Inpp5dinositol polyphosphate-5-phosphatase D0.924
Ikzf1IKAROS family zinc finger 10.860
Rag1recombination activating gene 10.854
Ptpn11protein tyrosine phosphatase, non-receptor type 110.852
Ptprcprotein tyrosine phosphatase, receptor type, C0.752
Tnftumor necrosis factor0.560
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.556
Foxp3forkhead box P30.389
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.377
Esr1estrogen receptor 1 (alpha)0.365
CblCasitas B-lineage lymphoma0.318
Ptenphosphatase and tensin homolog0.313
Cd19CD19 antigen0.277
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.259
Il4interleukin 40.233
Foxn1forkhead box N10.226
Il2rginterleukin 2 receptor, gamma chain0.202
Csf1colony stimulating factor 1 (macrophage)0.171
Stat3signal transducer and activator of transcription 30.169
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.167
FasFas (TNF receptor superfamily member 6)0.145
Trp53transformation related protein 530.143
Nrg1neuregulin 10.121
Grb2growth factor receptor bound protein 20.118
Il10interleukin 100.117
Lcklymphocyte protein tyrosine kinase0.111
Ifnginterferon gamma0.104
Retret proto-oncogene0.087
WasWiskott-Aldrich syndrome homolog (human)0.081
FynFyn proto-oncogene0.074
Csf1rcolony stimulating factor 1 receptor0.070
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.065
Col1a1collagen, type I, alpha 10.064
Dok2docking protein 20.061
Cd247CD247 antigen0.059
Prf1perforin 1 (pore forming protein)0.058
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.057
TcraT-cell receptor alpha chain0.053
Nr3c1nuclear receptor subfamily 3, group C, member 10.047
Itgb1integrin beta 1 (fibronectin receptor beta)0.045
Cd22CD22 antigen0.044
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.042
Lyz2lysozyme 20.042
BlnkB-cell linker0.042
Fcgr2bFc receptor, IgG, low affinity IIb0.040
Ccr6chemokine (C-C motif) receptor 60.037
Dok1docking protein 10.037
Ptk2PTK2 protein tyrosine kinase 20.036
Ntf3neurotrophin 30.036
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.035
Il6stinterleukin 6 signal transducer0.034
Plcg2phospholipase C, gamma 20.031
Eporerythropoietin receptor0.030
MefvMediterranean fever0.028
Kitlkit ligand0.028
Cdkn1bcyclin-dependent kinase inhibitor 1B0.027
Stat5bsignal transducer and activator of transcription 5B0.026
Phox2bpaired-like homeobox 2b0.026
Kitkit oncogene0.025
Stat5asignal transducer and activator of transcription 5A0.025
Il2interleukin 20.025
Map3k14mitogen-activated protein kinase kinase kinase 140.025
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.024
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.023
Ighimmunoglobulin heavy chain complex0.022
Nos3nitric oxide synthase 3, endothelial cell0.022
Itgb2integrin beta 20.021
S1pr1sphingosine-1-phosphate receptor 10.020
Hcls1hematopoietic cell specific Lyn substrate 10.020
Jak2Janus kinase 20.020
Ghrgrowth hormone receptor0.020
Ptpreprotein tyrosine phosphatase, receptor type, E0.019
Ptpn6protein tyrosine phosphatase, non-receptor type 60.019
Leprleptin receptor0.019
Il27rainterleukin 27 receptor, alpha0.018
Mmp9matrix metallopeptidase 90.018
Esr2estrogen receptor 2 (beta)0.018
Vangl2vang-like 2 (van gogh, Drosophila)0.016
Stat6signal transducer and activator of transcription 60.016
Cd4CD4 antigen0.016
Sykbspleen tyrosine kinase0.016
Rasal3RAS protein activator like 30.016
Il2rbinterleukin 2 receptor, beta chain0.015
Adam17a disintegrin and metallopeptidase domain 170.015
Cd180CD180 antigen0.015
Tgfb1transforming growth factor, beta 10.015
Clnkcytokine-dependent hematopoietic cell linker0.015
Cd40CD40 antigen0.014
Rac2RAS-related C3 botulinum substrate 20.014
Itgalintegrin alpha L0.014
Apcadenomatosis polyposis coli0.014
Egfrepidermal growth factor receptor0.013
BtkBruton agammaglobulinemia tyrosine kinase0.012
Meox2mesenchyme homeobox 20.012
Rgs14regulator of G-protein signaling 140.012
Lifleukemia inhibitory factor0.012
Nf1neurofibromatosis 10.011
S1pr4sphingosine-1-phosphate receptor 40.011
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.011
Shc1src homology 2 domain-containing transforming protein C10.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism