The network for 'copii coated vesicle budding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

copii coated vesicle budding

The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.

Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SEC23ASec23 homolog A (S. cerevisiae)0.717
CUL3cullin 30.523
SEC24DSEC24 family, member D (S. cerevisiae)0.460
SEC24ASEC24 family, member A (S. cerevisiae)0.346
ARF4ADP-ribosylation factor 40.070
SEC23BSec23 homolog B (S. cerevisiae)0.033
BTBD10BTB (POZ) domain containing 100.029
TMED2transmembrane emp24 domain trafficking protein 20.027
TMED10transmembrane emp24-like trafficking protein 10 (yeast)0.024
WNK4WNK lysine deficient protein kinase 40.021
ARCN1archain 10.018
GORASP2golgi reassembly stacking protein 2, 55kDa0.017
NFE2L2nuclear factor (erythroid-derived 2)-like 20.017
GOLGA2golgin A20.016
KLHL20kelch-like 20 (Drosophila)0.015
OCRLoculocerebrorenal syndrome of Lowe0.015
DAPK1death-associated protein kinase 10.015
DCUN1D1DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)0.012
USO1USO1 vesicle docking protein homolog (yeast)0.011
SEC31ASEC31 homolog A (S. cerevisiae)0.011
LMO4LIM domain only 40.011
ACBD3acyl-CoA binding domain containing 30.010
HMGCS13-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gorasp2golgi reassembly stacking protein 20.652
Copgcoatomer protein complex, subunit gamma0.483
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.251
Surf4surfeit gene 40.236
Slc35b1solute carrier family 35, member B10.220
Txndc5thioredoxin domain containing 50.212
Clptm1lCLPTM1-like0.198
Uso1USO1 homolog, vesicle docking protein (yeast)0.195
Copacoatomer protein complex subunit alpha0.193
Sec16aSEC16 homolog A (S. cerevisiae)0.187
P4hbprolyl 4-hydroxylase, beta polypeptide0.178
Sec31aSec31 homolog A (S. cerevisiae)0.155
Sec22bSEC22 vesicle trafficking protein homolog B (S. cerevisiae)0.124
Sec23aSEC23A (S. cerevisiae)0.106
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.099
Arf1ADP-ribosylation factor 10.096
GmppbGDP-mannose pyrophosphorylase B0.084
Copb1coatomer protein complex, subunit beta 10.080
Copecoatomer protein complex, subunit epsilon0.078
Tbrg1transforming growth factor beta regulated gene 10.077
Slc39a7solute carrier family 39 (zinc transporter), member 70.072
Ssr2signal sequence receptor, beta0.071
Maged1melanoma antigen, family D, 10.068
Ssr3signal sequence receptor, gamma0.065
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.063
Lrrc59leucine rich repeat containing 590.058
Sec24dSec24 related gene family, member D (S. cerevisiae)0.052
Arcn1archain 10.050
Akt1thymoma viral proto-oncogene 10.045
RhebRas homolog enriched in brain0.044
Sra1steroid receptor RNA activator 10.044
Slmapsarcolemma associated protein0.043
Calucalumenin0.043
Arl1ADP-ribosylation factor-like 10.040
Yipf5Yip1 domain family, member 50.040
Rab18RAB18, member RAS oncogene family0.039
Arhgap1Rho GTPase activating protein 10.038
Psma4proteasome (prosome, macropain) subunit, alpha type 40.038
Rpn2ribophorin II0.034
Vapavesicle-associated membrane protein, associated protein A0.033
Sel1lsel-1 suppressor of lin-12-like (C. elegans)0.032
Manfmesencephalic astrocyte-derived neurotrophic factor0.032
Prpf8pre-mRNA processing factor 80.031
Chmp1bchromatin modifying protein 1B0.029
Kdelr2KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 20.029
Erp44endoplasmic reticulum protein 440.028
Gosr2golgi SNAP receptor complex member 20.028
Chmp2achromatin modifying protein 2A0.027
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.027
Kpna1karyopherin (importin) alpha 10.027
Ddx3xDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked0.026
Hdlbphigh density lipoprotein (HDL) binding protein0.026
Creb3l2cAMP responsive element binding protein 3-like 20.025
Arfgap3ADP-ribosylation factor GTPase activating protein 30.024
Arf4ADP-ribosylation factor 40.024
Ppapdc1bphosphatidic acid phosphatase type 2 domain containing 1B0.023
Zc3h14zinc finger CCCH type containing 140.023
Papss13'-phosphoadenosine 5'-phosphosulfate synthase 10.022
Gbf1golgi-specific brefeldin A-resistance factor 10.022
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.022
Fndc3bfibronectin type III domain containing 3B0.022
Srprbsignal recognition particle receptor, B subunit0.021
Rab10RAB10, member RAS oncogene family0.021
Lman1lectin, mannose-binding, 10.021
Srp68signal recognition particle 680.021
Ostcoligosaccharyltransferase complex subunit0.021
Golga5golgi autoantigen, golgin subfamily a, 50.020
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.020
Fyttd1forty-two-three domain containing 10.020
Kctd9potassium channel tetramerisation domain containing 90.020
Osbpoxysterol binding protein0.019
Fam114a1family with sequence similarity 114, member A10.019
Ufsp2UFM1-specific peptidase 20.019
Stx5asyntaxin 5A0.019
Stx18syntaxin 180.019
Nucb1nucleobindin 10.018
Sec23bSEC23B (S. cerevisiae)0.018
C78339expressed sequence C783390.018
Mcfd2multiple coagulation factor deficiency 20.018
Gng3guanine nucleotide binding protein (G protein), gamma 30.018
Srp54csignal recognition particle 54C0.017
Tab3TGF-beta activated kinase 1/MAP3K7 binding protein 30.017
Morf4l2mortality factor 4 like 20.017
Cyb5r3cytochrome b5 reductase 30.016
Dad1defender against cell death 10.016
Oatornithine aminotransferase0.016
Kdelr3KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 30.016
Rock2Rho-associated coiled-coil containing protein kinase 20.016
Namptnicotinamide phosphoribosyltransferase0.016
Dapdeath-associated protein0.016
Spcs1signal peptidase complex subunit 1 homolog (S. cerevisiae)0.016
Armcx3armadillo repeat containing, X-linked 30.016
Tmem208transmembrane protein 2080.015
6330409N04RikRIKEN cDNA 6330409N04 gene0.015
Uba5ubiquitin-like modifier activating enzyme 50.015
Syap1synapse associated protein 10.015
Prdx3peroxiredoxin 30.015
1110067D22RikRIKEN cDNA 1110067D22 gene0.015
Prkcshprotein kinase C substrate 80K-H0.015
Supt5hsuppressor of Ty 5 homolog (S. cerevisiae)0.015
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SEC24Sec24p1.000
SEC31Sec31p0.997
SEC23Sec23p0.995
SEC16Sec16p0.844
SEC21Sec21p0.728
SFB3Sfb3p0.577
SEC13Sec13p0.467
SAR1Sar1p0.448
GRH1Grh1p0.340
SFB2Sfb2p0.294
SEC18Sec18p0.091
SED5Sed5p0.062
SEC1Sec1p0.059
SEC26Sec26p0.055
SEC4Sec4p0.031
SRD1Srd1p0.029
CRN1Crn1p0.029
LEU2Leu2p0.028
SEC20Sec20p0.028
ARG8Arg8p0.027
YLR264C-Ahypothetical protein0.024
YLR162Whypothetical protein0.023
HLJ1Hlj1p0.022
YOL038C-Ahypothetical protein0.022
GYL1Gyl1p0.022
BET3Bet3p0.021
SFT1Sft1p0.021
RET2Ret2p0.020
MER1Mer1p0.020
YIP3Yip3p0.020
ARP10Arp10p0.020
HXT3Hxt3p0.019
ACK1Ack1p0.019
YLR042Chypothetical protein0.019
SED4Sed4p0.018
CAB4Cab4p0.018
YPR157Whypothetical protein0.018
SPL2Spl2p0.018
YAR068Whypothetical protein0.018
ATP6Atp6p0.018
YKT6Ykt6p0.017
CUP1-1Cup1-1p0.016
ZPS1Zps1p0.016
OPT2Opt2p0.016
SEC7Sec7p0.015
AUA1Aua1p0.015
MF(ALPHA)2Mf(alpha)2p0.015
YBR013Chypothetical protein0.015
ALG12Alg12p0.015
FMT1Fmt1p0.014
BSC1Bsc1p0.014
YIR035Chypothetical protein0.014
ERD2Erd2p0.014
SCM4Scm4p0.014
YNL058Chypothetical protein0.014
TYE7Tye7p0.014
YLR040Chypothetical protein0.013
YOL013W-Ahypothetical protein0.013
PTR2Ptr2p0.013
CPD1Cpd1p0.013
TRS130Trs130p0.013
DIC1Dic1p0.013
ATR1Atr1p0.012
HPF1Hpf1p0.012
NRG2Nrg2p0.012
IZH4Izh4p0.012
BNA4Bna4p0.012
LRO1Lro1p0.012
SWC7Swc7p0.012
YPR096Chypothetical protein0.012
UPS3Ups3p0.012
TIR3Tir3p0.012
YHR035Whypothetical protein0.012
YAL064Whypothetical protein0.012
YJL107Chypothetical protein0.011
YAL037C-Ahypothetical protein0.011
ALT2Alt2p0.011
CRP1Crp1p0.011
YAR066Whypothetical protein0.011
MET8Met8p0.011
RNP1Rnp1p0.011
SCT1Sct1p0.011
COS12Cos12p0.011
LHS1Lhs1p0.011
YKR075Chypothetical protein0.011
CHA1Cha1p0.011
COG3Cog3p0.011
MSC7Msc7p0.010
ADH2Adh2p0.010
TSC3Tsc3p0.010
YGL006W-Ahypothetical protein0.010
REE1Ree1p0.010
DUR1,2Dur1,2p0.010
YCH1Ych1p0.010
RRT5Rrt5p0.010
YNL067W-Bhypothetical protein0.010
BOS1Bos1p0.010
ECT1Ect1p0.010