The network for 'cellular response to dna damage stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to dna damage stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

NameDescriptionProbabilityFunc Analog Organism
TP53tumor protein p531.000
BRCA1breast cancer 1, early onset1.000
MDM2Mdm2 p53 binding protein homolog (mouse)1.000
PCNAproliferating cell nuclear antigen1.000
H2AFXH2A histone family, member X1.000
CHEK1CHK1 checkpoint homolog (S. pombe)1.000
RB1retinoblastoma 11.000
BLMBloom syndrome, RecQ helicase-like1.000
PRKDCprotein kinase, DNA-activated, catalytic polypeptide1.000
CDK2cyclin-dependent kinase 21.000
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)1.000
RPA1replication protein A1, 70kDa1.000
CHEK2CHK2 checkpoint homolog (S. pombe)1.000
CREBBPCREB binding protein1.000
HDAC1histone deacetylase 11.000
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)1.000
RAD50RAD50 homolog (S. cerevisiae)1.000
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)1.000
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
PARP1poly (ADP-ribose) polymerase 11.000
MSH6mutS homolog 6 (E. coli)0.999
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.999
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.999
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.999
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.999
HNRNPKheterogeneous nuclear ribonucleoprotein K0.999
NBNnibrin0.999
E2F1E2F transcription factor 10.999
MDC1mediator of DNA-damage checkpoint 10.999
WRNWerner syndrome, RecQ helicase-like0.998
CSNK2A1casein kinase 2, alpha 1 polypeptide0.998
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.997
BRCA2breast cancer 2, early onset0.997
EGFRepidermal growth factor receptor0.996
SLX4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)0.995
CCNE1cyclin E10.995
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.995
MAPK14mitogen-activated protein kinase 140.994
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.993
EP300E1A binding protein p3000.993
TOPBP1topoisomerase (DNA) II binding protein 10.992
ATMataxia telangiectasia mutated0.991
RBBP8retinoblastoma binding protein 80.991
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.990
FANCAFanconi anemia, complementation group A0.990
CASP8caspase 8, apoptosis-related cysteine peptidase0.990
RAD1RAD1 homolog (S. pombe)0.989
XIAPX-linked inhibitor of apoptosis0.987
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.987
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.987
HIST1H3Dhistone cluster 1, H3d0.986
PMLpromyelocytic leukemia0.986
RAD18RAD18 homolog (S. cerevisiae)0.985
UBCubiquitin C0.985
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.984
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.984
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.984
CCND1cyclin D10.983
UCHL5ubiquitin carboxyl-terminal hydrolase L50.982
NCOA3nuclear receptor coactivator 30.982
DDB1damage-specific DNA binding protein 1, 127kDa0.982
RPA3replication protein A3, 14kDa0.981
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.981
DTLdenticleless homolog (Drosophila)0.981
ATRataxia telangiectasia and Rad3 related0.980
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.979
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.979
SIN3ASIN3 homolog A, transcription regulator (yeast)0.978
CDK4cyclin-dependent kinase 40.977
BCL2L1BCL2-like 10.977
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.977
HIST1H2BFhistone cluster 1, H2bf0.977
RAD51CRAD51 homolog C (S. cerevisiae)0.976
CHAF1Achromatin assembly factor 1, subunit A (p150)0.973
CCND3cyclin D30.973
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.973
CHUKconserved helix-loop-helix ubiquitous kinase0.970
MCM2minichromosome maintenance complex component 20.970
TERF2telomeric repeat binding factor 20.969
AKT1v-akt murine thymoma viral oncogene homolog 10.969
HIST1H2BDhistone cluster 1, H2bd0.966
TOP1topoisomerase (DNA) I0.964
SMC1Astructural maintenance of chromosomes 1A0.964
SIRT1sirtuin 10.961
HIST1H1Chistone cluster 1, H1c0.960
HIST1H2BGhistone cluster 1, H2bg0.960
MDM4Mdm4 p53 binding protein homolog (mouse)0.960
TFDP1transcription factor Dp-10.959
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.957
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.955
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.954
STK4serine/threonine kinase 40.953
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.952
SMC6structural maintenance of chromosomes 60.950
FEN1flap structure-specific endonuclease 10.950
BCL2B-cell CLL/lymphoma 20.949
RPA2replication protein A2, 32kDa0.947
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.947
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.946
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.945
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
his-16Protein HIS-160.843
rpt-5Protein RPT-50.668
his-3Protein HIS-30.647
his-45Protein HIS-450.576
rpn-12Protein RPN-120.440
rpt-3Protein RPT-30.426
his-29Protein HIS-290.421
his-59Protein HIS-590.420
his-1Protein HIS-10.350
his-5Protein HIS-50.339
his-47Protein HIS-470.328
CELE_Y41E3.11Protein Y41E3.110.304
his-52Protein HIS-520.296
acly-2Protein ACLY-20.294
F52B5.3Protein F52B5.30.289
his-42Protein HIS-420.269
rpn-2Protein RPN-20.247
his-51Protein HIS-510.244
npp-15Protein NPP-150.242
npl-4.2Protein NPL-4.20.230
rrf-3Protein RRF-30.220
rpn-5Protein RPN-50.216
rpn-10Protein RPN-100.211
dcr-1Protein DCR-10.207
pas-2Protein PAS-20.206
zyg-9Protein ZYG-90.203
his-39Protein HIS-390.200
mat-3Protein MAT-30.199
pas-4Protein PAS-40.195
pme-1Protein PME-10.192
F10C2.4Protein F10C2.40.189
D1081.8Protein D1081.80.184
rpn-3Protein RPN-30.183
mcm-2Protein MCM-20.182
chk-1Protein CHK-10.179
his-48Protein HIS-480.171
rpt-2Protein RPT-20.167
D2030.8Protein D2030.80.166
his-31Protein HIS-310.163
prpf-4Protein PRPF-40.157
larp-5Protein LARP-50.156
his-61Protein HIS-610.154
htz-1Protein HTZ-10.153
gpr-2Protein GPR-20.153
dnj-5Protein DNJ-50.151
F54E12.2Protein F54E12.20.150
sas-5Protein SAS-50.150
srgp-1Protein SRGP-10.145
let-502Protein LET-5020.145
his-4Protein HIS-40.144
akt-1Protein AKT-10.143
atl-1Protein ATL-10.142
his-64Protein HIS-640.142
vab-1Protein VAB-10.141
pabp-2Protein PABP-20.139
ndc-80Protein NDC-800.137
his-30Protein HIS-300.136
capg-2Protein CAPG-20.135
egl-18Protein EGL-180.135
pbs-5Protein PBS-50.134
ucr-2.3Protein UCR-2.30.133
his-63Protein HIS-630.128
his-2Protein HIS-20.126
ima-2Protein IMA-20.126
hda-1Protein HDA-10.125
Y55D9A.2Protein Y55D9A.20.123
CELE_F17C11.10Protein F17C11.100.121
H21P03.2Protein H21P03.20.121
C30A5.3Protein C30A5.30.118
mis-12Protein MIS-120.117
mcm-5Protein MCM-50.116
R04F11.3Protein R04F11.30.115
npp-9Protein NPP-90.115
prp-3Protein PRP-30.114
sid-1Protein SID-10.114
set-1Protein SET-10.114
his-6Protein HIS-60.113
cdc-48.1Protein CDC-48.10.113
his-50Protein HIS-500.112
R148.3Protein R148.30.111
Y110A7A.9Protein Y110A7A.90.111
retr-1Protein RETR-10.111
pbs-7Protein PBS-70.109
F10B5.8Protein F10B5.80.107
lea-1Protein LEA-10.107
rpn-7Protein RPN-70.107
F22H10.3Protein F22H10.30.106
R186.7Protein R186.70.104
mop-25.3Protein MOP-25.30.103
mdt-8Protein MDT-80.103
B0432.13Protein B0432.130.102
gpb-1Protein GPB-10.101
pri-2Protein PRI-20.100
CELE_Y69A2AR.16Protein Y69A2AR.160.096
nasp-1Protein NASP-10.094
R11A8.7Protein R11A8.70.094
cku-80Protein CKU-800.093
dpf-3Protein DPF-30.093
CELE_D1054.3Protein D1054.30.093
tag-307Protein TAG-3070.093
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fanciFanconi anemia, complementation group I0.454
mapk14amitogen-activated protein kinase 14a0.422
fzd7afrizzled homolog 7a0.257
ccnd1cyclin D10.227
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.219
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.208
psmb3proteasome (prosome, macropain) subunit, beta type, 30.207
brca2breast cancer 2, early onset0.203
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.193
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.193
tgif1TGFB-induced factor homeobox 10.189
pola2polymerase (DNA directed), alpha 20.187
psma8proteasome (prosome, macropain) subunit, alpha type, 80.183
psmb2proteasome (prosome, macropain) subunit, beta type, 20.174
wlswntless homolog (Drosophila)0.166
ppp4caprotein phosphatase 4 (formerly X), catalytic subunit a0.159
tagln2transgelin 20.153
aaasachalasia, adrenocortical insufficiency, alacrimia0.152
hmgb2bhigh-mobility group box 2b0.146
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.146
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.146
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.142
celf1cugbp, Elav-like family member 10.136
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.135
hat1histone acetyltransferase 10.130
fen1flap structure-specific endonuclease 10.128
cxcr4bchemokine (C-X-C motif), receptor 4b0.121
rasl11bRAS-like, family 11, member B0.116
naspnuclear autoantigenic sperm protein (histone-binding)0.114
psmb1proteasome (prosome, macropain) subunit, beta type, 10.114
bcl2l1bcl2-like 10.113
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.112
brd2abromodomain-containing 2a0.112
nr2f2nuclear receptor subfamily 2, group F, member 20.111
mapk3mitogen-activated protein kinase 30.110
psma4proteasome (prosome, macropain) subunit, alpha type, 40.107
hugHuG0.105
psmc1bproteasome (prosome, macropain) 26S subunit, ATPase, 1b0.105
ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.104
ccnl1cyclin L10.104
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.095
mmp9matrix metalloproteinase 90.092
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.091
baxabcl2-associated X protein, a0.091
ddb2damage-specific DNA binding protein 20.087
psma2proteasome (prosome, macropain) subunit, alpha type, 20.086
smc3structural maintenance of chromosomes 30.085
cry5cryptochrome 50.084
csnk1dacasein kinase 1, delta a0.083
efnb2aephrin B2a0.083
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.083
si:ch211-1n9.7si:ch211-1n9.70.080
stc1lstanniocalcin 1, like0.079
asf1bbASF1 anti-silencing function 1 homolog Bb0.079
mcl1amyeloid cell leukemia sequence 1a0.078
spry2sprouty homolog 20.078
psma5proteasome (prosome, macropain) subunit, alpha type,50.076
rfc4replication factor C (activator 1) 40.075
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.074
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.073
dusp1dual specificity phosphatase 10.071
smndc1survival motor neuron domain containing 10.068
cdh1cadherin 1, epithelial0.067
zgc:113143zgc:1131430.066
naa20N(alpha)-acetyltransferase 20, NatB catalytic subunit0.063
dab1adisabled homolog 1a (Drosophila)0.063
fancd2Fanconi anemia, complementation group D20.061
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.061
chek1CHK1 checkpoint homolog (S. pombe)0.060
pak2ap21 (CDKN1A)-activated kinase 2a0.060
bcl2B-cell leukemia/lymphoma 20.059
cdc25cell division cycle 25 homolog0.059
mycamyelocytomatosis oncogene a0.059
ccdc94coiled-coil domain containing 940.058
mmp2matrix metalloproteinase 20.058
eif4eeukaryotic translation initiation factor 4e0.058
fabp7afatty acid binding protein 7, brain, a0.057
wdhd1WD repeat and HMG-box DNA binding protein 10.056
sox4aSRY-box containing gene 4a0.056
mlh1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.055
rnaseh2aribonuclease H2, subunit A0.054
psmb4proteasome (prosome, macropain) subunit, beta type, 40.054
plxnb2aplexin b2a0.054
abcf1ATP-binding cassette, sub-family F (GCN20), member 10.054
rplp2ribosomal protein, large P20.054
lmx1b.1LIM homeobox transcription factor 1, beta 10.053
per2period homolog 2 (Drosophila)0.053
dnmt5DNA (cytosine-5-)-methyltransferase 50.053
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.052
caprin1acell cycle associated protein 1a0.052
sox7SRY-box containing gene 70.052
zgc:92648zgc:926480.052
zgc:123326zgc:1233260.052
cand1cullin-associated and neddylation-dissociated 10.052
prdm9PR domain containing 90.052
dusp6dual specificity phosphatase 60.052
hs3st3b1bheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b0.052
aurkbaurora kinase B0.051
snrpd1small nuclear ribonucleoprotein D1 polypeptide0.050
stmn1bstathmin 1b0.050
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
lokloki1.000
mus205mutagen-sensitive 2050.998
tefutelomere fusion0.997
skpACG16983 gene product from transcript CG16983-RD0.991
p53CG33336 gene product from transcript CG33336-RB0.991
Caf1Chromatin assembly factor 1 subunit0.989
hayhaywire0.988
DNApol-etaCG7143 gene product from transcript CG7143-RA0.984
mre11meiotic recombination 110.976
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.969
rad50CG6339 gene product from transcript CG6339-RD0.967
Pros29Proteasome 29kD subunit0.953
CSN4COP9 complex homolog subunit 40.949
CDC45LCG3658 gene product from transcript CG3658-RA0.944
okrokra0.939
mus308mutagen-sensitive 3080.930
Rpn9CG10230 gene product from transcript CG10230-RB0.927
sxcsuper sex combs0.904
S6kRPS6-p70-protein kinase0.897
Prosbeta2Proteasome beta2 subunit0.888
RpA-70Replication Protein A 700.883
Dcr-2Dicer-20.867
RfC4Replication factor C subunit 40.864
kiskismet0.862
RbfRetinoblastoma-family protein0.857
BRWD3CG31132 gene product from transcript CG31132-RA0.852
mus210mutagen-sensitive 2100.835
HLHm7E(spl) region transcript m70.832
E(spl)Enhancer of split0.831
spn-Bspindle B0.818
nbsCG6754 gene product from transcript CG6754-RC0.812
Prosbeta3Proteasome beta3 subunit0.812
Brca2Breast cancer 2, early onset homolog0.804
Prosbeta5Proteasome beta5 subunit0.787
Prosbeta1Proteasome beta1 subunit0.786
CkIIbetaCasein kinase II beta subunit0.772
Akt1CG4006 gene product from transcript CG4006-RA0.771
IswiImitation SWI0.766
mus101mutagen-sensitive 1010.766
bskbasket0.765
Jafrac1thioredoxin peroxidase 10.762
smt3CG4494 gene product from transcript CG4494-RA0.757
dadaughterless0.754
mei-9meiotic 90.749
Su(H)Suppressor of Hairless0.747
Pp2A-29BProtein phosphatase 2A at 29B0.740
Sin3ACG8815 gene product from transcript CG8815-RC0.729
mus201mutagen-sensitive 2010.729
Pros26Proteasome 26kD subunit0.720
Mnn1Menin 10.715
RecQ5homolog of RecQ0.694
RASSF8CG5053 gene product from transcript CG5053-RA0.684
mus301mutagen-sensitive 3010.684
panpangolin0.683
His2AvHistone H2A variant0.672
Prosalpha7Proteasome alpha7 subunit0.665
mofmales absent on the first0.655
ebiCG4063 gene product from transcript CG4063-RA0.654
MerMerlin0.652
phlpole hole0.651
MED17Mediator complex subunit 170.647
CG9772CG9772 gene product from transcript CG9772-RB0.637
DpDP transcription factor0.632
Rev1CG12189 gene product from transcript CG12189-RA0.627
nejnejire0.625
Nipped-ACG33554 gene product from transcript CG33554-RE0.625
snostrawberry notch0.623
Rpt1CG1341 gene product from transcript CG1341-RA0.611
escextra sexcombs0.603
CG5524CG5524 gene product from transcript CG5524-RA0.592
mei-41meiotic 410.591
CG5794CG5794 gene product from transcript CG5794-RB0.588
Rca1Regulator of cyclin A10.579
reptreptin0.579
Mcm7Minichromosome maintenance 70.567
CG7288CG7288 gene product from transcript CG7288-RA0.564
DNApol-alpha73DNA polymerase alpha 73kD0.553
Pi3K92ECG4141 gene product from transcript CG4141-RB0.550
keykenny0.539
CycDCyclin D0.533
lin19lin-19-like0.530
Rpn11CG18174 gene product from transcript CG18174-RA0.529
Sir2CG5216 gene product from transcript CG5216-RA0.525
RpII215RNA polymerase II 215kD subunit0.523
Su(var)2-10Suppressor of variegation 2-100.520
MBD-R2CG10042 gene product from transcript CG10042-RB0.520
Rpt4CG3455 gene product from transcript CG3455-RA0.515
Chrac-14CG13399 gene product from transcript CG13399-RA0.509
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.509
CSN6COP9 complex homolog subunit 60.507
SsrpStructure specific recognition protein0.498
SpnSpinophilin0.493
Pk61CProtein kinase 61C0.491
Nf1Neurofibromin 10.489
CG1240CG1240 gene product from transcript CG1240-RA0.484
pr-set7CG3307 gene product from transcript CG3307-RC0.481
babobaboon0.481
IncenpInner centromere protein0.475
Prosalpha5Proteasome alpha5 subunit0.473
dre4CG1828 gene product from transcript CG1828-RB0.460
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Mdm2transformed mouse 3T3 cell double minute 21.000
Ptenphosphatase and tensin homolog1.000
Brca2breast cancer 21.000
Brca1breast cancer 11.000
Rb1retinoblastoma 11.000
Atmataxia telangiectasia mutated homolog (human)0.999
Cdkn1bcyclin-dependent kinase inhibitor 1B0.999
Mdm4transformed mouse 3T3 cell double minute 40.999
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.998
Ighimmunoglobulin heavy chain complex0.997
E2f1E2F transcription factor 10.997
Ctnnb1catenin (cadherin associated protein), beta 10.994
Tcf3transcription factor 30.993
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.993
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.992
Suz12suppressor of zeste 12 homolog (Drosophila)0.991
Msh2mutS homolog 2 (E. coli)0.988
Pcnaproliferating cell nuclear antigen0.988
Arntlaryl hydrocarbon receptor nuclear translocator-like0.987
Nbnnibrin0.986
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.985
Apcadenomatosis polyposis coli0.983
Tnftumor necrosis factor0.980
Cdt1chromatin licensing and DNA replication factor 10.976
Timelesstimeless homolog (Drosophila)0.975
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.973
Cdk4cyclin-dependent kinase 40.972
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.962
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.960
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.958
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.953
Mybl2myeloblastosis oncogene-like 20.949
Cdk1cyclin-dependent kinase 10.936
Map3k7mitogen-activated protein kinase kinase kinase 70.935
Mtormechanistic target of rapamycin (serine/threonine kinase)0.932
Ash2lash2 (absent, small, or homeotic)-like (Drosophila)0.932
Ikzf1IKAROS family zinc finger 10.927
Rev1REV1 homolog (S. cerevisiae)0.927
WrnWerner syndrome homolog (human)0.925
Psma5proteasome (prosome, macropain) subunit, alpha type 50.924
Clockcircadian locomotor output cycles kaput0.916
Prim1DNA primase, p49 subunit0.897
Parp1poly (ADP-ribose) polymerase family, member 10.895
Rnf2ring finger protein 20.894
Xpaxeroderma pigmentosum, complementation group A0.892
Stag1stromal antigen 10.891
Mapk8mitogen-activated protein kinase 80.889
BrafBraf transforming gene0.885
BlmBloom syndrome, RecQ helicase-like0.877
Mcl1myeloid cell leukemia sequence 10.876
BaxBCL2-associated X protein0.875
Vegfavascular endothelial growth factor A0.875
Psma4proteasome (prosome, macropain) subunit, alpha type 40.874
Usp1ubiquitin specific peptidase 10.872
Mcm5minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)0.869
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.862
Psma7proteasome (prosome, macropain) subunit, alpha type 70.860
Cdk2cyclin-dependent kinase 20.854
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.851
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.846
Psmb4proteasome (prosome, macropain) subunit, beta type 40.841
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.840
Orc1origin recognition complex, subunit 10.835
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.833
Trim28tripartite motif-containing 280.832
Psmb7proteasome (prosome, macropain) subunit, beta type 70.830
Hprthypoxanthine guanine phosphoribosyl transferase0.829
Casp4caspase 4, apoptosis-related cysteine peptidase0.829
Psmb2proteasome (prosome, macropain) subunit, beta type 20.823
Notch1Notch gene homolog 1 (Drosophila)0.821
SkilSKI-like0.819
Per1period homolog 1 (Drosophila)0.818
Atf2activating transcription factor 20.817
Psma2proteasome (prosome, macropain) subunit, alpha type 20.816
Tsc1tuberous sclerosis 10.813
Cry1cryptochrome 1 (photolyase-like)0.804
Per2period homolog 2 (Drosophila)0.800
Brd4bromodomain containing 40.798
Terf1telomeric repeat binding factor 10.798
Cdkn2acyclin-dependent kinase inhibitor 2A0.792
CtcfCCCTC-binding factor0.791
Vaspvasodilator-stimulated phosphoprotein0.790
Rbl1retinoblastoma-like 1 (p107)0.783
Mycmyelocytomatosis oncogene0.782
Hat1histone aminotransferase 10.780
Hellshelicase, lymphoid specific0.779
Chek1checkpoint kinase 1 homolog (S. pombe)0.776
Ccne1cyclin E10.775
Foxo3forkhead box O30.773
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.773
Smad4MAD homolog 4 (Drosophila)0.772
Psma1proteasome (prosome, macropain) subunit, alpha type 10.771
CrebbpCREB binding protein0.770
Pold3polymerase (DNA-directed), delta 3, accessory subunit0.759
Ikbkbinhibitor of kappaB kinase beta0.758
Wdhd1WD repeat and HMG-box DNA binding protein 10.758
Ncoa6nuclear receptor coactivator 60.756
Hmgb1high mobility group box 10.756
Rbl2retinoblastoma-like 20.747
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.231
Psmb3proteasome (prosome, macropain) subunit, beta type 30.119
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.099
Ptbp1polypyrimidine tract binding protein 10.086
Psme2proteasome (prosome, macropain) activator subunit 20.080
Psmb2proteasome (prosome, macropain) subunit, beta type 20.064
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.055
Cdk4cyclin-dependent kinase 40.045
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.040
Psma4proteasome (prosome, macropain) subunit, alpha type 40.036
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.033
Rfc4replication factor C (activator 1) 40.032
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.031
Timelesstimeless homolog (Drosophila)0.029
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.027
Oaz1ornithine decarboxylase antizyme 10.027
Stip1stress-induced phosphoprotein 10.027
Mapk1mitogen activated protein kinase 10.026
Kifc1kinesin family member C10.026
Taok1TAO kinase 10.025
Cdk2cyclin dependent kinase 20.025
Icam1intercellular adhesion molecule 10.025
Arf6ADP-ribosylation factor 60.025
Top2atopoisomerase (DNA) II alpha0.024
Tmpothymopoietin0.024
Atf2activating transcription factor 20.023
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.023
Psmb7proteasome (prosome, macropain) subunit, beta type 70.022
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.022
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.022
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.021
Ptges3prostaglandin E synthase 3 (cytosolic)0.020
Rrm2ribonucleotide reductase M20.020
Irf1interferon regulatory factor 10.020
Ube2cubiquitin-conjugating enzyme E2C0.019
Rpa2replication protein A20.018
Nsfl1cNSFL1 (p97) cofactor (p47)0.018
Creb1cAMP responsive element binding protein 10.018
Arntaryl hydrocarbon receptor nuclear translocator0.017
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.017
Cherpcalcium homeostasis endoplasmic reticulum protein0.017
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.016
Sf1splicing factor 10.016
Mdm2Mdm2 p53 binding protein homolog (mouse)0.016
Cxcl16chemokine (C-X-C motif) ligand 160.016
Foxm1forkhead box M10.016
Cand1cullin-associated and neddylation-dissociated 10.015
Tymsthymidylate synthetase0.015
Usp47ubiquitin specific peptidase 470.015
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.015
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.015
Lmnb1lamin B10.015
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.015
Psmb4proteasome (prosome, macropain) subunit, beta type 40.014
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.014
Psma5proteasome (prosome, macropain) subunit, alpha type 50.014
Psma7proteasome (prosome, macropain) subunit, alpha type 70.014
Actbactin, beta0.014
Pfn1profilin 10.014
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.014
Zfp36zinc finger protein 360.014
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.014
Ifi30interferon gamma inducible protein 300.014
Top2btopoisomerase (DNA) II beta0.014
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.013
Vcpvalosin-containing protein0.013
Ifitm3interferon induced transmembrane protein 30.013
Myo1bmyosin Ib0.013
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.013
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.013
Txnrd1thioredoxin reductase 10.013
Zc3h15zinc finger CCCH-type containing 150.013
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.013
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.013
Lbrlamin B receptor0.013
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.013
Tp53tumor protein p530.013
Timp1TIMP metallopeptidase inhibitor 10.013
Errfi1ERBB receptor feedback inhibitor 10.012
Usp9xubiquitin specific peptidase 9, X-linked0.012
Mcm6minichromosome maintenance complex component 60.012
Racgap1Rac GTPase-activating protein 10.012
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.012
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.012
Tmsb4xthymosin beta 4, X-linked0.012
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.012
B3gat1beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)0.012
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.011
Zfand6zinc finger, AN1-type domain 60.011
Socs3suppressor of cytokine signaling 30.011
Ssrp1structure specific recognition protein 10.011
Apex1APEX nuclease (multifunctional DNA repair enzyme) 10.011
Ireb2iron responsive element binding protein 20.011
Mark2MAP/microtubule affinity-regulating kinase 20.011
Actg1actin, gamma 10.011
Cops6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.010
Ubcubiquitin C0.010
Actr10actin-related protein 10 homolog (S. cerevisiae)0.010
Exoc5exocyst complex component 50.010
Raf1v-raf-leukemia viral oncogene 10.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
HHF1Hhf1p0.999
RAD50Rad50p0.999
RAD9Rad9p0.999
SRS2Srs2p0.999
RAD18Rad18p0.999
RAD24Rad24p0.998
RFA1Rfa1p0.998
RAD54Rad54p0.997
RAD1Rad1p0.997
RAD52Rad52p0.996
SMC6Smc6p0.995
POL30Pol30p0.994
RAD23Rad23p0.990
RAD5Rad5p0.988
RAD53Rad53p0.984
RAD57Rad57p0.981
MEC1Mec1p0.980
MSH6Msh6p0.980
SGS1Sgs1p0.979
DDC1Ddc1p0.977
YAP1Yap1p0.976
RAD10Rad10p0.974
YAF9Yaf9p0.974
EAF1Eaf1p0.971
MSH2Msh2p0.970
RAD14Rad14p0.970
CDC45Cdc45p0.969
PRE2Pre2p0.968
SIC1Sic1p0.966
RAD4Rad4p0.965
MCM4Mcm4p0.963
ARP4Arp4p0.959
XRS2Xrs2p0.955
PIF1Pif1p0.953
CTF4Ctf4p0.951
PMS1Pms1p0.951
RTF1Rtf1p0.947
ELG1Elg1p0.946
RAD27Rad27p0.945
MLH1Mlh1p0.941
MRC1Mrc1p0.940
REV3Rev3p0.938
HHO1Hho1p0.934
KCS1Kcs1p0.928
CLB3Clb3p0.927
RPN1Rpn1p0.920
ARP8Arp8p0.920
DMC1Dmc1p0.915
RPN10Rpn10p0.904
TEL1Tel1p0.902
MUS81Mus81p0.899
RPT6Rpt6p0.893
SMC5Smc5p0.890
RRP6Rrp6p0.885
POL31Pol31p0.881
RAD17Rad17p0.876
RFA2Rfa2p0.873
RAD16Rad16p0.870
PPH22Pph22p0.868
RAD51Rad51p0.867
POL3Pol3p0.865
DIA2Dia2p0.860
SWC4Swc4p0.852
TOR2Tor2p0.849
ESA1Esa1p0.847
MRE11Mre11p0.836
DUN1Dun1p0.835
SEM1Sem1p0.834
PSF1Psf1p0.830
UBR1Ubr1p0.829
MCM6Mcm6p0.828
POL2Pol2p0.822
RAD30Rad30p0.821
RTT109Rtt109p0.819
APN1Apn1p0.814
EAF5Eaf5p0.814
SLX4Slx4p0.808
RAD26Rad26p0.802
DCC1Dcc1p0.795
RPN12Rpn12p0.792
RAD59Rad59p0.788
NSE3Nse3p0.786
PSY2Psy2p0.775
HPR1Hpr1p0.774
RRM3Rrm3p0.772
SIR2Sir2p0.771
MEC3Mec3p0.769
CDC4Cdc4p0.768
POL32Pol32p0.764
RPT3Rpt3p0.746
GBP2Gbp2p0.743
EPL1Epl1p0.737
RPT1Rpt1p0.730
DPB11Dpb11p0.728
RSC2Rsc2p0.720
SLX8Slx8p0.715
NTG2Ntg2p0.714
PUP1Pup1p0.714
RAD3Rad3p0.713
MMS21Mms21p0.713