The network for 'histone serine phosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone serine phosphorylation

The modification of histones by addition of a phosphate group to a serine residue.

Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MAPK14mitogen-activated protein kinase 140.993
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.922
INCENPinner centromere protein antigens 135/155kDa0.906
CDK1cyclin-dependent kinase 10.860
BIRC5baculoviral IAP repeat containing 50.852
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.831
AURKAaurora kinase A0.795
MAPK1mitogen-activated protein kinase 10.719
HTThuntingtin0.618
GAS2L3growth arrest-specific 2 like 30.604
PLK1polo-like kinase 10.573
MAPK3mitogen-activated protein kinase 30.524
PRMT6protein arginine methyltransferase 60.465
CDCA8cell division cycle associated 80.365
COASYCoA synthase0.282
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.266
CDK2cyclin-dependent kinase 20.241
GSK3Bglycogen synthase kinase 3 beta0.225
RCC1regulator of chromosome condensation 10.211
HNRNPABheterogeneous nuclear ribonucleoprotein A/B0.206
RNF19Aring finger protein 19A0.203
PTTG1pituitary tumor-transforming 10.190
CDC20cell division cycle 20 homolog (S. cerevisiae)0.182
PIAS4protein inhibitor of activated STAT, 40.181
RICTORRPTOR independent companion of MTOR, complex 20.174
EEF2Keukaryotic elongation factor-2 kinase0.170
CCNA2cyclin A20.169
CDKN3cyclin-dependent kinase inhibitor 30.165
PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.165
MAPK8mitogen-activated protein kinase 80.160
ACACAacetyl-CoA carboxylase alpha0.145
DUSP1dual specificity phosphatase 10.137
TP53tumor protein p530.136
NEK2NIMA (never in mitosis gene a)-related kinase 20.126
PDK1pyruvate dehydrogenase kinase, isozyme 10.123
CCDC101coiled-coil domain containing 1010.116
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.114
PRKAG2protein kinase, AMP-activated, gamma 2 non-catalytic subunit0.107
DUSP3dual specificity phosphatase 30.088
SETD7SET domain containing (lysine methyltransferase) 70.088
TTKTTK protein kinase0.087
C19orf46chromosome 19 open reading frame 460.078
SGOL1shugoshin-like 1 (S. pombe)0.076
AURKBaurora kinase B0.074
PDPK13-phosphoinositide dependent protein kinase-10.070
MAPTmicrotubule-associated protein tau0.068
ITSN1intersectin 1 (SH3 domain protein)0.063
CCNB2cyclin B20.061
NCLnucleolin0.060
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.056
PRKCAprotein kinase C, alpha0.055
MAP3K7mitogen-activated protein kinase kinase kinase 70.055
UBE2Cubiquitin-conjugating enzyme E2C0.054
HMGB1high mobility group box 10.054
CDC25Ccell division cycle 25 homolog C (S. pombe)0.052
FZD5frizzled homolog 5 (Drosophila)0.051
MAP2K1mitogen-activated protein kinase kinase 10.051
ING5inhibitor of growth family, member 50.050
SMSspermine synthase0.050
KIF2Ckinesin family member 2C0.043
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.042
CDC27cell division cycle 27 homolog (S. cerevisiae)0.042
DUSP7dual specificity phosphatase 70.041
LMO4LIM domain only 40.040
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.038
MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)0.038
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 10.038
C10orf116chromosome 10 open reading frame 1160.038
DDAH2dimethylarginine dimethylaminohydrolase 20.037
EP300E1A binding protein p3000.036
MPP1membrane protein, palmitoylated 1, 55kDa0.035
ZNF746zinc finger protein 7460.035
DHX34DEAH (Asp-Glu-Ala-His) box polypeptide 340.034
GTSE1G-2 and S-phase expressed 10.034
PTPRRprotein tyrosine phosphatase, receptor type, R0.033
SMAD7SMAD family member 70.032
FNIP1folliculin interacting protein 10.032
HOXB7homeobox B70.032
MAP2K4mitogen-activated protein kinase kinase 40.030
VRK2vaccinia related kinase 20.029
CCNE1cyclin E10.028
PSRC1proline/serine-rich coiled-coil 10.028
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.027
CDCA5cell division cycle associated 50.027
TBCDtubulin folding cofactor D0.027
ILVBLilvB (bacterial acetolactate synthase)-like0.026
CKS2CDC28 protein kinase regulatory subunit 20.026
CHEK2CHK2 checkpoint homolog (S. pombe)0.026
PTPRJprotein tyrosine phosphatase, receptor type, J0.026
C6orf136chromosome 6 open reading frame 1360.026
PPIDpeptidylprolyl isomerase D0.025
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.025
PKMYT1protein kinase, membrane associated tyrosine/threonine 10.024
MTORmechanistic target of rapamycin (serine/threonine kinase)0.024
MKNK1MAP kinase interacting serine/threonine kinase 10.024
PRKAA1protein kinase, AMP-activated, alpha 1 catalytic subunit0.024
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.023
EIF3Ceukaryotic translation initiation factor 3, subunit C0.023
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.023
CLTCclathrin, heavy chain (Hc)0.021
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cdk1cyclin-dependent kinase 10.998
Ccna2cyclin A20.973
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.956
Prc1protein regulator of cytokinesis 10.925
Birc5baculoviral IAP repeat-containing 50.908
Ccnb2cyclin B20.885
Kif20akinesin family member 20A0.846
Kif22kinesin family member 220.602
Ube2cubiquitin-conjugating enzyme E2C0.575
Ckap2cytoskeleton associated protein 20.510
Cdca8cell division cycle associated 80.505
Ccnb1cyclin B10.467
Racgap1Rac GTPase-activating protein 10.392
Plk1polo-like kinase 1 (Drosophila)0.376
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.346
Ect2ect2 oncogene0.324
Mki67antigen identified by monoclonal antibody Ki 670.324
H2afxH2A histone family, member X0.299
Cks2CDC28 protein kinase regulatory subunit 20.280
Ncaphnon-SMC condensin I complex, subunit H0.219
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.183
Kif11kinesin family member 110.174
Rrm2ribonucleotide reductase M20.162
Aurkaaurora kinase A0.159
Hmmrhyaluronan mediated motility receptor (RHAMM)0.125
Cenpacentromere protein A0.123
PbkPDZ binding kinase0.108
Dlgap5discs, large (Drosophila) homolog-associated protein 50.097
Cdkn3cyclin-dependent kinase inhibitor 30.094
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.090
Aurkbaurora kinase B0.090
Cdc25ccell division cycle 25 homolog C (S. pombe)0.090
Kif2ckinesin family member 2C0.087
Kif23kinesin family member 230.084
Cdca5cell division cycle associated 50.073
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.070
Ccdc99coiled-coil domain containing 990.069
Kif4kinesin family member 40.069
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.066
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.060
Top2atopoisomerase (DNA) II alpha0.055
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.052
2810417H13RikRIKEN cDNA 2810417H13 gene0.033
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.032
Anlnanillin, actin binding protein0.023
Tk1thymidine kinase 10.022
Melkmaternal embryonic leucine zipper kinase0.018
Tacc3transforming, acidic coiled-coil containing protein 30.018
Cep55centrosomal protein 550.014
Gsg2germ cell-specific gene 20.013
Ccnfcyclin F0.013
Ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.013
Fam64afamily with sequence similarity 64, member A0.011
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.011
Tcf19transcription factor 190.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Racgap1Rac GTPase-activating protein 10.399
Top2atopoisomerase (DNA) II alpha0.318
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.291
Hmmrhyaluronan mediated motility receptor (RHAMM)0.286
RGD1564560similar to RCK0.250
Kifc1kinesin family member C10.208
Cdk1cyclin-dependent kinase 10.185
Prc1protein regulator of cytokinesis 10.131
Traf4af1TRAF4 associated factor 10.115
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.064
Pttg1pituitary tumor-transforming 10.056
Rab14RAB14, member RAS oncogene family0.054
Fen1flap structure-specific endonuclease 10.050
Ccnb1cyclin B10.050
LOC100366119Mpv17 transgene, kidney disease mutant-like (predicted)-like0.049
Kif2ckinesin family member 2C0.039
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.033
Ube2cubiquitin-conjugating enzyme E2C0.028
Stmn1stathmin 10.025
Kif22kinesin family member 220.024
Plk4polo-like kinase 4 (Drosophila)0.023
Mcm7minichromosome maintenance complex component 70.023
Birc5baculoviral IAP repeat-containing 50.022
Spag5sperm associated antigen 50.021
Ccnb2cyclin B20.020
Cdca8cell division cycle associated 80.020
Tymsthymidylate synthetase0.019
Kif4kinesin family member 40.019
Rrm2ribonucleotide reductase M20.017
Prim2primase, DNA, polypeptide 20.015
Zfp91zinc finger protein 910.014
Espl1extra spindle pole bodies homolog 1 (S. cerevisiae)0.014
Rbm9RNA binding motif protein 90.013
Aurkaaurora kinase A0.012
Rad51ap1RAD51 associated protein 10.012
Cdkn3cyclin-dependent kinase inhibitor 30.011
Mcm6minichromosome maintenance complex component 60.011
Aurkbaurora kinase B0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism