The network for 'cd8 positive alpha beta t cell activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cd8 positive alpha beta t cell activation

The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

NameDescriptionProbabilityFunc Analog Organism
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 61.000
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.999
PILRApaired immunoglobin-like type 2 receptor alpha0.998
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.993
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.993
CCL4chemokine (C-C motif) ligand 40.969
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.963
IDEinsulin-degrading enzyme0.957
IL8interleukin 80.954
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.887
CCL8chemokine (C-C motif) ligand 80.872
PTAFRplatelet-activating factor receptor0.871
TRAF1TNF receptor-associated factor 10.832
IL1Binterleukin 1, beta0.829
MEOX1mesenchyme homeobox 10.801
CXCL2chemokine (C-X-C motif) ligand 20.800
CXCL9chemokine (C-X-C motif) ligand 90.780
SIGLEC7sialic acid binding Ig-like lectin 70.773
CXCL3chemokine (C-X-C motif) ligand 30.734
CCR1chemokine (C-C motif) receptor 10.692
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.681
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.640
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.619
HLA-Amajor histocompatibility complex, class I, A0.618
CCL2chemokine (C-C motif) ligand 20.596
IL6interleukin 6 (interferon, beta 2)0.588
CCR5chemokine (C-C motif) receptor 50.580
CCL13chemokine (C-C motif) ligand 130.562
CCL5chemokine (C-C motif) ligand 50.561
HK3hexokinase 3 (white cell)0.559
EPORerythropoietin receptor0.538
HLA-Bmajor histocompatibility complex, class I, B0.487
DPP4dipeptidyl-peptidase 40.477
BCL2A1BCL2-related protein A10.415
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.393
TYMPthymidine phosphorylase0.371
PTPN6protein tyrosine phosphatase, non-receptor type 60.318
TREM1triggering receptor expressed on myeloid cells 10.300
AKT2v-akt murine thymoma viral oncogene homolog 20.286
GNLYgranulysin0.273
CXCL11chemokine (C-X-C motif) ligand 110.247
NLRP3NLR family, pyrin domain containing 30.242
CCL7chemokine (C-C motif) ligand 70.236
PRDM1PR domain containing 1, with ZNF domain0.225
CCR4chemokine (C-C motif) receptor 40.220
AOAHacyloxyacyl hydrolase (neutrophil)0.208
CCR3chemokine (C-C motif) receptor 30.201
GZMBgranzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)0.197
CXCL5chemokine (C-X-C motif) ligand 50.185
FPR3formyl peptide receptor 30.181
IL1RNinterleukin 1 receptor antagonist0.180
CCL11chemokine (C-C motif) ligand 110.171
MMP12matrix metallopeptidase 12 (macrophage elastase)0.171
RGS1regulator of G-protein signaling 10.170
IL10interleukin 100.166
IL7Rinterleukin 7 receptor0.161
AMBRA1autophagy/beclin-1 regulator 10.159
PIAS1protein inhibitor of activated STAT, 10.142
CCL3chemokine (C-C motif) ligand 30.141
IFNGinterferon, gamma0.138
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.138
CCR7chemokine (C-C motif) receptor 70.135
TNFtumor necrosis factor0.134
CXCL10chemokine (C-X-C motif) ligand 100.133
SELEselectin E0.131
LILRA3leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 30.129
IL15RAinterleukin 15 receptor, alpha0.125
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.124
LILRB4leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 40.119
BIRC3baculoviral IAP repeat containing 30.115
TNFAIP6tumor necrosis factor, alpha-induced protein 60.112
NOD2nucleotide-binding oligomerization domain containing 20.110
CCL21chemokine (C-C motif) ligand 210.105
GATA4GATA binding protein 40.105
HLA-Gmajor histocompatibility complex, class I, G0.103
CH25Hcholesterol 25-hydroxylase0.102
CCL3L3chemokine (C-C motif) ligand 3-like 30.102
CD83CD83 molecule0.101
TNFRSF9tumor necrosis factor receptor superfamily, member 90.099
SLAMF7SLAM family member 70.098
BATFbasic leucine zipper transcription factor, ATF-like0.093
TBX21T-box 210.089
SIRPB1signal-regulatory protein beta 10.088
ZC3H12Azinc finger CCCH-type containing 12A0.088
TBX5T-box 50.088
CXCL13chemokine (C-X-C motif) ligand 130.088
CCL23chemokine (C-C motif) ligand 230.086
PIK3R5phosphoinositide-3-kinase, regulatory subunit 50.083
MSCmusculin0.081
XCL2chemokine (C motif) ligand 20.080
NR4A3nuclear receptor subfamily 4, group A, member 30.078
CXCR6chemokine (C-X-C motif) receptor 60.078
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.076
CSF1colony stimulating factor 1 (macrophage)0.075
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.071
CCL22chemokine (C-C motif) ligand 220.068
C2complement component 20.066
CCL19chemokine (C-C motif) ligand 190.066
CD33CD33 molecule0.064
TMSB4Xthymosin beta 4, X-linked0.063
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.740
Pitx1paired-like homeodomain transcription factor 10.453
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.180
Stat2signal transducer and activator of transcription 20.121
Bcl2B-cell leukemia/lymphoma 20.095
Hoxa1homeobox A10.095
Bak1BCL2-antagonist/killer 10.053
Ighimmunoglobulin heavy chain complex0.045
Il27rainterleukin 27 receptor, alpha0.041
Fgfr2fibroblast growth factor receptor 20.037
Lef1lymphoid enhancer binding factor 10.035
Cd19CD19 antigen0.030
BaxBCL2-associated X protein0.030
Wt1Wilms tumor 1 homolog0.029
Tbx3T-box 30.029
Sfpi1SFFV proviral integration 10.028
Stat5bsignal transducer and activator of transcription 5B0.027
Lmx1aLIM homeobox transcription factor 1 alpha0.026
Stat5asignal transducer and activator of transcription 5A0.026
Zeb1zinc finger E-box binding homeobox 10.021
Socs1suppressor of cytokine signaling 10.019
Fgf10fibroblast growth factor 100.018
Tbx5T-box 50.018
Tcfcp2l1transcription factor CP2-like 10.016
Jag1jagged 10.015
Vangl2vang-like 2 (van gogh, Drosophila)0.015
1810019J16RikRIKEN cDNA 1810019J16 gene0.015
Trp63transformation related protein 630.014
Foxg1forkhead box G10.013
Fgfr3fibroblast growth factor receptor 30.013
Trp53transformation related protein 530.013
Pitx2paired-like homeodomain transcription factor 20.013
Irf4interferon regulatory factor 40.013
Lrp5low density lipoprotein receptor-related protein 50.012
Ttc7tetratricopeptide repeat domain 70.012
Ikzf1IKAROS family zinc finger 10.012
Wnt9bwingless-type MMTV integration site 9B0.012
Chd7chromodomain helicase DNA binding protein 70.012
Bbc3BCL2 binding component 30.011
Irf8interferon regulatory factor 80.011
Prf1perforin 1 (pore forming protein)0.011
Mcl1myeloid cell leukemia sequence 10.011
Rnf2ring finger protein 20.011
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.011
TcrbT-cell receptor beta chain0.010
TcrdT-cell receptor delta chain0.010
Bcl6B-cell leukemia/lymphoma 60.010
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism